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| 1 | 固相萃取(SPE)和衍生化条件的对GC/MS及LC/MS/MS法检测莱克多巴胺灵敏度的影响(英文)显示文摘本实验探讨影响GC/MS以及LC/MS/MS检测灵敏度的影响因素。对GC/MS法的固相萃取(SPE)和衍生化条件进行优化,测试了SPE、加热时间、温度、溶液及碱基化等因素。同时测试这些条件对LC/MC/MC法的灵敏度。结果表明,碱基化为影响GC/MS法灵敏度的主要因素,能提高灵敏度,对衍生化条件也有影响。通过对样本进行固相萃取,碱基化处理,GC/MS法的灵敏度为0.5ng/mL,LC/MC/MC法的为0.25ng/mL。采用这种更灵敏的方法,尿液中莱克多巴胺的测试窗口期可由2d提高到6d。经过优化的GC/MS法及LC/MS/MS方法灵敏度更高,适合猪尿中莱克多巴胺的检测。 | 刘晓云 何小维 王国洪 Christine Moore Cynthia Counter 杨连生 Michael Vincent James Soares | 2010 | 现代食品科技2010，26，11： | 2 |
| 2 | Incidence and Management of Life-Threatening Adverse Events During Cardiac Catheterization for Congenital Heart Disease显示文摘 | C. Huie Lin Sanjeet Hegde Audrey C. Marshall Diego Porras Kimberlee Gauvreau David T. Balzer Robert H. Beekman Alejandro Torres Julie A. Vincent John W. Moore Ralf Holzer Laurie Armsby Lisa Bergersen | 2014 | Pediatric Cardiology2014，，1： | 1 |
| 3 | Robot-assisted Laparoscopic Dismembered Pyeloplasty for Ureteropelvic Junction Obstruction: A Multi-institutional Experience显示文摘 | Ananthakrishnan Sivaraman Raymond J. Leveillee Manoj B. Patel Sanket Chauhan Jorge E. Bracho Charles R. Moore Rafael F. Coelho Kenneth J. Palmer Oscar Schatloff Vincent G. Bird Ravi Munver Vipul R. Patel | 2012 | Urology2012，，2： | 1 |
| 4 | X-ray volumetric imaging in image-guided radiotherapy: The new standard in on-treatment imaging显示文摘 | Catherine A. McBain Ann M. Henry Jonathan Sykes Ali Amer Tom Marchant Christopher M. Moore Julie Davies Julia Stratford Claire McCarthy Bridget Porritt Peter Williams Vincent S. Khoo Pat Price | 2006 | International Journal of Radiation Oncology Biology Physics2006，，2： | 1 |
| 5 | Replication and packaging of HIV envelope genes in novel adeno-associated virus vector system 显示文摘 | Vincent KA Moore GK Haigwood NL | 1990 | Vaccine1990，90，： | 1 |
| 6 | AB032. Exploring the effects of a retinal prosthesis on visual hallucinations related to Charles Bonnet syndrome显示文摘Background:A first occurrence in the province of Quebec(Canada)of the use of a retinal prosthesis system(RPS)by a patient with a Charles Bonnet syndrome(CBS)provides a rare opportunity to explore the effects of this system on visual hallucinations(VH)related to CBS.Considering that the RPS artificially induces a visual perception and that VH related to CBS occur in cases of significant vision loss,this study aimed to explore whether the recovery of a visual perception could affect the nature and frequency of VH related to CBS.Methods:This is a case study with time series and repeated experimentation:a pre-intervention measure to establish the baseline level,two implant activation periods(A1 and A2)and a post-intervention measure(3 for each activation).The study is based on a 65-year-old man with retinitis pigmentosa.He has been functionally blind for about ten years and was completely blind at the time of the study.He began to perceive VH corresponding to the CBS after a significant decrease of his visual fields.At the time of the study,these VH were frequent and often disturbing.After receiving the Argus II RPS,he participated,along with INLB staff,in an intensive rehabilitation program aiming at optimizing the use of the system.To explore the effects of the RPS,we collected visual,cognitive,and mood-related data and documented the VH using the Charles Bonnet Syndrome Screening Questionnaire(Cantin et al.,2018).Results:The visual acuity and visual field measurements show a significant improvement with the use of the RPS(visual acuity of 2.3 logMAR and visual fields of 12 degrees).Measurements of cognitive functions have shown high,stable,and close to the maximum performances.Mood data revealed low and relatively stable depression and anxiety scores over the course of the study.The documented VH showed the characteristic features of CBS.The nature and frequency of VH have varied widely over the study period.Conclusions:The RPS improved the visual perceptions of the study participant and VH that were observed correspond to the CBS definition.Despite the partial recovery of some form of visual perception induced by the RPS,the variations in the nature and frequency of the VH have occurred independently of the use of the system:therefore,they cannot be linked.While it is true that the Argus II RPS allows blind users to recover some form of visual perception,it remains very limited and the implanted subject remains functionally blind.It is then legitimate to assume that the visual perceptions generated by the implant may be insufficient to have an effect on VH related to CBS.Further studies are needed to support the conclusions of this innovative study. | Vincent Moore Marie Courchesne Mathieu Carignan Sylvie Cantin Frédérique Poncet | 2019 | Annals of Eye Science2019，，1： | 0 |
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