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| 1 | Rapid measurement of indocyanine green retention by pulse spectrophotometry: a validation study in 70 patients with Child-Pugh A cirrhosis before hepatectomy for hepatocellular carcinoma显示文摘BACKGROUND: The indocyanine green (ICG) retention test is the most popular liver function test for selecting patients for major hepatectomy. Traditionally, it is done using spectrophotometry with serial blood sampling. The newly- developed pulse spectrophotometry is a faster alternative, but its accuracy on Child-Pugh A cirrhotic patients undergoing hepatectomy for hepatocellular carcinoma has not been well documented. This study aimed to assess the accuracy of the LiMON , one of the pulse spectrophotometry systems, in measuring preoperative ICG retention in these patients and to devise an easy formula for conversion of the results so that they can be compared with classical literature records where ICG retention was measured by the traditional method. METHODS: We measured the liver function of 70 Child-Pugh A cirrhotic patients before hepatectomy for hepatocellular carcinoma from September 2008 to January 2009. ICG retention at 15 minutes measured by traditional spectrophotometry (ICGR15) was compared with ICG retention at 15 minutes measured by the LiMON (ICGR15(L)). RESULTS: The median ICGR15 was 14.7% (5.6%-32%) and the median ICGR15(L) was 10.4% (1.2%-28%). The mean difference between them was -4.3606. There was a strong correlation between ICGR15 and ICGR15(L) (correlation coefficient, 0.844; 95% confidence interval, 0.762-0.899). The following formula was devised: ICGR15=1.16×ICGR15(L)+2.73.CONCLUSIONS: The LiMON provides a fast and repeatable way to measure ICG retention at 15 minutes, but with constant underestimation of the real value. Therefore, when comparing results obtained by traditional spectrophotometry and the LiMON, adjustment of results from the latter is necessary, and this can be done with a simple mathematical calculation using the above formula. | Tan To Cheung See Ching Chan Kenneth SH Chok Albert CY Chan Wan Ching Yu Ronnie TP Poon Chung Mau Lo Sheung Tat Fan | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，3： | 8 |
| 2 | Laser-assisted hatching improves clinical outcomes of vitrified -warmed blastocysts developed from low-grade cleavage-stage embryos: a prospective randomized study 显示文摘 | Wan CY Song C Diao LH | 2014 | Reprod Biomed Online2014，28，5： | 1 |
| 3 | Effects of Manganese Deficiency on Growth and Contents of Active Constituents of Glycyrrhiza uralensis Fisch显示文摘 | Wang D Wan CY Wang WQ | 2012 | Communications in Soil Science and Plant Analysis2012，43，： | 1 |
| 4 | Effects of Manganese Deficiency on Growth and Contents of Active Constituents of Glycyrrhiza uralensis Fisch显示文摘 | Wang D Wan CY Wang WQ | 2012 | Communications in Soil Science and Plant Analysis2012，43，22： | 1 |
| 5 | Neutralizing antibody response in the patients with hand,foot and mouth disease to enteroviru 71 and its clinical implications 显示文摘 | Yang CF Deng CY Wan JF | 2011 | Virology Journal2011，8，6： | 1 |
| 6 | Are there gen- der differences in coronary artery disease The Malaysian National Cardiovascular Disease Database-Percutaneous Coronary Intervention (NCVD-PCI) Registry显示文摘 | Lee CY Hairi NN Wan Ahmad WA | 2013 | PLoS One2013，8，72： | 1 |
| 7 | The use of non-invasive brain stimulation techniques to facilitate recovery from post-stroke aphasia 显示文摘 | Schlaug G Mairchina S Wan CY | 2011 | Neuropsychol Rev2011，21，3： | 1 |
| 8 | Intensive therapy in- duces contralateral white matter changes in chronic stroke patients with Broca's aphasia显示文摘 | Wan CY Zheng X Marchina S | 2014 | Brain Lang2014，136，： | 1 |
| 9 | Noutrophil separation technique for noonates显示文摘 | Alfred YC Tam CY Yeunq | 1999 | British Journal of Biomedical Science1999，56，3： | 1 |
| 10 | Comparison of IP micromobility protocols显示文摘 | Campbell AT Gomez J Kim S Wan CY Turanyi ZR Valko AG | 2002 | IEEE WirelessCommunications2002，9，1： | 1 |
| 11 | From music making to speaking: engaging the mirror neuron system in autism 显示文摘 | Wan CY Demaine K Zipse L | 2010 | Brain Res Bull2010，82，34： | 1 |
| 12 | Laser-assisted hatchingimproves clinical outcomes of vitrified-warmed blastocysts devel-oped from low-grade cleavage-stage embryos : a prospectiverandomized study显示文摘 | Wan CY Song C Diao LH | 2014 | Reprod Biomed Online2014，28，5： | 1 |
| 13 | The Therapeutic ef- fects of singing in neurological disorders显示文摘 | Wan CY Ruber T Hohmann A | 2010 | Music Percept2010，27，4： | 1 |
| 14 | Auditory-motor mappingtraining as an intervention to facilitate speech output innon-verbal children with autism: a proof of concept study 显示文摘 | Wan CY Bazen L Baars R | 2011 | PLoS One2011，6，25： | 1 |
| 15 | Specific detection of fungal pathogens by 18S rRNA gene PCR in microbial keratitis显示文摘 | Embong Z Wan Hitam WH Yean CY | 2008 | BMC Ophthalmol2008，8，： | 1 |
| 16 | 显示文摘 | Wan CY Qiao XY Zhang Y 等 | 2003 | J Appl Polym Sci2003，89，： | 1 |
| 17 | Neutrophil separation technique for neonates显示文摘 | Wan TS Tam AY Yeunq CY | 1999 | Br J Bio Sci1999，56，3： | 1 |
| 18 | Anaplastic Carcinoma of the Thyroid显示文摘 | Lo CY Lam KY Wan KY | | 0，，03： | 1 |
| 19 | Irregular poliovirus vaccination correlates to pulmonary edema of hand, foot,and mouth disease 显示文摘 | Deng CY Yang CF Wan JF | 2011 | Clin 'Vaccine Immund2011，18，9： | 1 |
| 20 | The use of non-invasive brain stimulation techniques to facilitate recovery from post-stroke aphasia显示文摘 | Schlaug G Marchina S Wan CY | 2011 | Neuropsychol Rev2011，21，3： | 1 |
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