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| 1 | Evaluation of the weakening behavior of gas on the coal strength and its quantitative influence on the coal deformation显示文摘The coal strength and deformation properties are key factors affecting safe coal mining and highefficiency coalbed methane(CBM)development.In this paper,reconstituted coal samples are chosen to investigate the weakening behavior of gas on coal strength,meanwhile,its effects on coal deformation are quantitatively evaluated.The results indicate that the weakening degree of gas on coal strength is closely related to the confining stress and gas pressure.Compared with non-gas-saturated coals,the maximum weakening ratios of adsorbed gas to coal strength are 10.58%,18.12%,8.55%and 14.65%under the conditions of confining stress CS=3 MPa and gas pressure GP=1 MPa,CS=3 MPa and GP=2 MPa,CS=4 MPa and GP=1 MPa,and CS=4 MPa and GP=2 MPa,respectively.Furthermore,the maximum weakening ratios of free gas to coal strength are 18.27%,36.54%,14.79%and 29.58%,respectively,under above four conditions.The maximum coal bulk strain decreases as particle sizes of coal powders increase,and it has a maximum value of 0.0227 and a minimum value of 0.0191 in particle size ranges of 0.01–0.041 and 0.5–1 mm.Under the same conditions,the coal bulk strain increases with increasing gas pressure,revealing that coal deformation properties can be enhanced by gas. | Haijun Guo Kai Wang Yuchen Wu Hanlu Tang Jianguo Wu Lianhe Guan Chenyang Chang Chao Xu | 2021 | International Journal of Mining Science and Technology2021，31，3： | 2 |
| 2 | DFT study of new bipyrazole derivatives and their potential activity as corrosion inhibitors显示文摘 | Hengliang Wang Xueye Wang Hanlu Wang Ling Wang Aihong Liu | 2007 | J Mol Model2007，13，： | 1 |
| 3 | Theoretical and experimental specific capacitance of polyaniline in sulfuric acid显示文摘 | Hanlu Li Jixiao Wang Qingxian Chu Zhi Wang Fengbao Zhang Shichang Wang | 2009 | Journal of Power Sources2009，，2： | 1 |
| 4 | Expression of renal cubilin and its potential role in tubulointerstitial inflammation induced by albumin overload显示文摘 | Jurong Yang Yani He Haiying Shen Hanlu Ding Kailong Li Huiming Wang | 2008 | Frontiers of Medicine in China2008，，1： | 1 |
| 5 | Theoretical and experimental specific capacitance of polyaniline in sulfuric acid显示文摘 | Li Hanlu Wang Jixiao Chu Qinxian | 2009 | J Power Sources2009，190，： | 1 |
| 6 | Theoretical and experimental specific capacitance of polyaniline in sulfuric acid 显示文摘 | Li Hanlu Wang Jixiao Chu Qingxin | 2009 | Journal of Power Source2009，190，2： | 1 |
| 7 | Catalytic oxidative desulfurization of gasoline using phosphotungstic acid supported on MWW zeolite显示文摘Catalysts for the desulfurization of gasoline samples were synthesized via the immobilization of well-dispersed phosphotungstic acid(HPW)on Mobil compo-sition of matter-twenty-two(MWW)zeolite.Characteriza-tion results indicated that these catalysts possess a mesoporous structure with the retention of the Keggin structure of immobilized HPW.Relevant reaction para-meters influencing sulfur removal were systematically investigated,including HPW loading,catalyst dosage,temperature,initial S-concentration,molar ratio of oxidant to sulfide(O/S),volume ratio of MeCN to model oil(Ext./oil),and sulfide species.The 40 wt-%HPW/MWW catalyst exhibited the highest catalytic activity with 99.6%dibenzothiophene sulfur removal from prepared samples.The 40 wt-%HPW/MWW catalyst was recycled four times and could be easily regenerated.Finally,as an exploratory study,straight-run-gasoline and fluid catalytic cracking gasoline were employed to accurately evaluate the desulfurization performance of 40 wt-%HPW/MWW.Our research provides new insights into the development and application of catalysts for desulfurization of gasoline. | Hanlu Wang Idris Jibrin Xingye Zeng | 2020 | Frontiers of Chemical Science and Engineering2020，14，4： | 1 |
| 8 | Real-time Subsynchronous Control Interaction Monitoring Using Improved Intrinsic Time-scale Decomposition显示文摘In recent years,subsynchronous control interaction(SSCI)has frequently taken place in renewable-connected power systems.To counter this issue,utilities have been seeking tools for fast and accurate identification of SSCI events.The main challenges of SSCI monitoring are the time-varying nature and uncertain modes of SSCI events.Accordingly,this paper presents a simple but effective method that takes advantage of intrinsic time-scale decomposition(ITD).The main purpose is to improve the accuracy and robustness of ITD by incorporating the least-squares method.Results show that the proposed method strikes a good balance between dynamic performance and estimation accuracy.More importantly,the method does not require any prior information,and its performance is therefore not affected by the frequency constitution of the SSCI.Comprehensive comparative studies are conducted to demonstrate the usefulness of the method through synthetic signals,electromagnetic temporary program(EMTP)simulations,and field-recorded SSCI data.Finally,real-time simulation tests are conducted to show the feasibility of the method for real-time monitoring. | Yang Wang Hanlu Yang Xiaorong Xie Xiaomei Yang Guanrun Chen | 2023 | Journal of Modern Power Systems and Clean Energy2023，11，3： | 1 |
| 9 | Unexpected phosphodiesterase activity at low pH of a dinuclear copper-13 cyclodextrin corn plex显示文摘 | ZHAO Meng WANG Hanlu MAO Zongwan | 2011 | Chemical Communication2011，47，： | 1 |
| 10 | Theoretical studies on fluorescence of phenol and 1-naphthol in both acid and alkali solutions显示文摘 | Wang Hanlu Wang Xueye | 2006 | Journal of Molecular2006，770，： | 1 |
| 11 | Design and implementation of unmanned aerial vehicle localization and light tracking system显示文摘Unmanned aerial vehicles(UAV)are applied widely and profoundly in various fields.Moreover,high-precision positioning and tracking in multiple scenarios are the core requirements for UAV usage.To ensure stable communication of UAVs in denial environments with substantial electromagnetic interference,a systematic solution is proposed based on a deep learning algorithm for target detection and visible light for UAV tracking.Considering the cost and computational power limitations on the hardware,the you only look once(YOLO)v4-Tiny model is used for static target detection of the UAV model.For UAV tracking,and a light tracker that can adjust the angle of emitted light and focus it on the target is used for dynamic tracking processing.Thus,achieving the primary conditions of UAV optical communication with good secrecy is also suitable for dynamic situations.The UAV tracker positions the UAV model by returning the coordinates and calculating the time delay,and then controls the spotlight to target the UAV.In order to facilitate the deployment of deep learning models on hardware devices,the lighter and more efficient model is selected after comparison.The trained model can achieve 99.25%accuracy on the test set.The dynamic target detection can reach 20 frames per second(FPS)on a computer with an MX520 graphics processing unit(GPU)and 6 GB of random access memory(RAM).Dynamic target detection on a Jetson Nano can reach 5.4 FPS. | Xu Ming Dong Chen Li Hanlu Luo Qiming Wang Lizi Zhang Wanru Liu Huixin | 2023 | The Journal of China Universities of Posts and Telecommunications2023，30，4： | 0 |
| 12 | Expression of renal cubilin and its potential role in tubulointerstitial inflammation induced by albumin overload显示文摘Sustained proteinuria is an independent risk factor leading to kidney fibrosis and end-stage renal fail-ure.Over-reabsorption of filtered proteins,notably albu-min,has been proved to trigger interstitial inflammation and fibrosis in proteinuric renal disease.Cubilin,an endo-cytic receptor expressed on the renal tubular brush bor-der,is responsible for albumin reabsorption in physiologic condition.However,little is known about whether it is required for activation of tubular cells induced by albu-min overload.In this work,we investigated the change of cubilin expression and its potential role in albumin-induced up-regulation of chemokines synthesis in vivo and in vitro.Twenty-six patients with nephrotic syndrome were enrolled in this study.Proximal tubule uptake of albumin,expression of apical membrane cubilin and infiltrating cells in kidney interstitium were determined by immunocytochemistry.In vitro,the transcription of cubilin in HK2 cells after exposure to albumin was ana-lyzed by real-time PCR.Endocytosis of albumin in HK2 cells was examined by fluorescent microscope.The influ-ence of inhibition of cubilin on albumin-induced expres-sions of monocyte chemoattractant protein 1(MCP-1)and regulated upon activation normal T-cell expressed and secreted(RANTES)was investigated by Western blot.The intensity of luminal cubilin and tubular accu-mulation of albumin were significantly increased in nephrotic kidneys.The expression of MCP-1 and RANTES was up-regulated,and there were spatial rela-tionships in localization between these chemokines and cubilin as well as intracellular albumin in kidney tissues.Infiltration of CD-3 and ED-1-positive cells was predom-inant in tubulointerstitial areas displaying signs of increases of cubilin expression and albumin accumula-tion.In vitro,the transcription of cubilin mRNA in HK2 cells was enhanced after 24 h exposure to albumin in a dose-dependent manner.Inhibition of endocytosis of albumin by antisense cubilin nucleotide markedly reduced expression of MCP-1 and RANTES.Cubilin was required for handling a greater amount of protein in nephrotic status and albumin-induced production of MCP-1 and RANTES by renal tubular cells,which further initiated tubulointerstitial inflammation in proteinuric disease. | Jurong YANG Yani HE Haiying SHEN Hanlu DING Kailong LI Huiming WANG | 2008 | Frontiers of Medicine2008，2，1： | 0 |
| 13 | Defect detection in near-surface blind zone using Green’s function reconstruction of diffuse field sector scanning显示文摘Aiming at the problem of defect detection in the near-surface blind zone of structure,the detection method for reconstruction of Green^function by sector scanning of diffuse field is developed.Based on the theoretical analysis of the Green^function reconstruction of diffuse field sector scanning,a 5 MHz ultrasonic phased array probe is utilized to test the near-surface defects of an aluminum block.Some factors that affect the imaging results,such as the delay time,time window length and scanning methods,are further analyzed.The results show that this method can effectively detect defects from 1.5 mm to 3.0 mm in the near-surface blind zone of the aluminum block.The effective diffusion time of the sector scanning method is longer than the full matrix capture method by more than 0.5 ms.In particularly,within the effective diffusion time,as the receiving delay time and the time window length increase,the imaging quality is improved.This research work provides an effective and feasible method for ultrasonic detection of defects in the near-surface blind zone. | WANG Hanlu HE Liyuan MI Yuan WU Dawei | 2021 | Chinese Journal of Acoustics2021，40，3： | 0 |
| 14 | Prediction of lipid nanoparticles for mRNA vaccines by the machine learning algorithm显示文摘Lipid nanoparticle(LNP) is commonly used to deliver mRNA vaccines.Currently,LNP optimization primarily relies on screening ionizable lipids by traditional experiments which consumes intensive cost and time.Current study attempts to apply computational methods to accelerate the LNP development for mRNA vaccines.Firstly,325 data samples of mRNA vaccine LNP formulations with IgG titer were collected.The machine learning algorithm,lightGBM,was used to build a prediction model with good performance(R^(2)>0.87).More importantly,the critical substructures of ionizable lipids in LNPs were identified by the algorithm,which well agreed with published results.The animal experimental results showed that LNP using DLin-MC3-DMA(MC3) as ionizable lipid with an N/P ratio at 6:1 induced higher efficiency in mice than LNP with SM-102,which was consistent with the model prediction.Molecular dynamic modeling further investigated the molecular mechanism of LNPs used in the experiment.The result showed that the lipid molecules aggregated to form LNPs,and mRNA molecules twined around the LNPs.In summary,the machine learning predictive model for LNP-based mRNA vaccines was first developed,validated by experiments,and further integrated with molecular modeling.The prediction model can be used for virtual screening of LNP formulations in the future. | Wei Wang Shuo Feng Zhuyifan Ye Hanlu Gao Jinzhong Lin Defang Ouyang | 2022 | Acta Pharmaceutica Sinica B2022，12，6： | 0 |
| 15 | Advances in the research field of osteoporosis in cold areas显示文摘While osteoporosis is a chronic disease caused by multiple factors,it is also a risk factor for fractures.At present,numerous risk factors for osteoporosis and secondary fractures have been identified,including sunlight,physical fitness,gender,age,trauma,dietary habits,tobacco,alcohol,drugs,air quality,and genetics.Despite that factors such as long winters,short daylight hours,less daily physical activity,air pollution,low calcium and high salt diet,and sedentary lifestyle could negatively impact the bones of residents in the alpine regions of northern China,the direct effect of low-temperature stimulation on bone growth and development remains unclear.In this study,by reviewing current research progress related to osteoporosis and fracture risk in northern China,we proposed appropriate preventive measures for different risk factors to reduce the occurrence of osteoporosis and fracture in cold areas of northern China. | Ping Zhou Hanlu Zhang Yizhen Nie Yimeng Zhang Yongchen Wang | 2022 | Frigid Zone Medicine2022，2，1： | 0 |
| 16 | A Review of the Eco-Environmental Impacts of the South-to-North Water Diversion:Implications for Interbasin Water Transfers显示文摘Interbasin water-transfer schemes provide an engineering solution for reconciling the conflict between water demand and availability.In the context of climate change,which brings great uncertainties to water resource distribution,interbasin water transfer plays an increasingly important role in the global water–food–energy nexus.However,the transfer of water resources simultaneously changes the hydrological regime and the characteristics of local water bodies,affecting biotic communities accordingly.Compared with high economic and technical inputs water-transfer projects require,the environmental and ecological implications of water-transfer schemes have been inadequately addressed.This work selects the largest water-transfer project in China,the South-to-North Water Diversion(SNWD)Project,to critically review its eco-environmental impacts on donor and recipient basins,as well as on regions along the diversion route.The two operated routes of the SNWD Project represent two typical water diversion approaches:The Middle Route uses an excavated canal,while the East Route connects existent river channels.An overview of the eco-environmental implications of these two routes is valuable for the design and optimization of future water-transfer megaprojects. | Hanlu Yan Yuqing Lin Qiuwen Chen Jianyun Zhang Shufeng He Tao Feng Zhiyuan Wang Cheng Chen Jue Ding | 2023 | Engineering2023，，11： | 0 |
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