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| 1 | 用RFLP方法研究陕西省主要小麦品种遗传多样性及其演变显示文摘研究用RFLP方法,对我国主要小麦产区,陕西省40年代以来广为种植的小麦品种的遗传多样性进行了研究,结果表明,占总带数26.2%的HINDII酶的RFLP带具有遗传多态性。24个小麦品种平均遗传相似系数为0.948。53.8%的探针显示了多态性。平均多态性信息含量指数为0.252。陕西省小麦品种遗传多样性以70年代为最高,之后开始降低。 | 朱列层 唐国顺 HAZEN S P KIM H S WARD R W | 1999 | 西北植物学报1999，19，2： | 11 |
| 2 | Model combining pre-transplant tumor biomarkers and tumor size shows more utility in predicting hepatocellular carcinoma recurrence and survival than the BALAD models显示文摘AIM To assess the performance of BALAD, BALAD-2 and their component biomarkers in predicting outcome of hepatocellular carcinoma(HCC) patients after liver transplant.METHODS BALAD score and BALAD-2 class are derived from bilirubin, albumin, alpha-fetoprotein(AFP), Lens culinaris agglutinin-reactive AFP(AFP-L3), and des-gammacarboxyprothrombin(DCP). Pre-transplant AFP, AFP-L3 and DCP were measured in 113 patients transplanted for HCC from 2000 to 2008. Hazard ratios(HR) for recurrence and death were calculated. Univariate and multivariate regression analyses were conducted. C-statistics were used to compare biomarker-based to predictive models. RESULTS During a median follow-up of 12.2 years, 38 patients recurred and 87 died. The HRs for recurrence in patients with elevated AFP, AFP-L3, and DCP defined by BALAD cut-off values were 2.42(1.18-5.00), 1.86(0.98-3.52), and 2.83(1.42-5.61), respectively. For BALAD, the HRs for recurrence and death per unit increased score were 1.48(1.15-1.91) and 1.59(1.28-1.97). For BALAD-2, the HRs for recurrence and death per unit increased class were 1.45(1.06-1.98) and 1.38(1.09-1.76). For recurrence prediction, the combination of three biomarkers had the highest c-statistic of 0.66 vs. 0.64, 0.61, 0.53, and 0.53 for BALAD, BALAD-2, Milan, and UCSF, respectively. Similarly, for death prediction, the combination of three biomarkers had the highest c-statistic of 0.66 vs 0.65,0.61, 0.52, and 0.50 for BALAD, BALAD-2, Milan, and UCSF. A new model combining biomarkers with tumor size at the time of transplant(S-LAD) demonstrated the highest predictive capability with c-statistics of 0.71 and 0.69 for recurrence and death. CONCLUSION BALAD and BALAD-2 are valid in transplant HCC patients, but less predictive than the three biomarkers in combination or the three biomarkers in combination with maximal tumor diameter(S-LAD). | Nicha Wongjarupong Gabriela M Negron-Ocasio Roongruedee Chaiteerakij Benyam D Addissie Essa A Mohamed Kristin C Mara William S Harmsen J Paul Theobald Brian E Peters Joseph G Balsanek Melissa M Ward Nasra H Giama Sudhakar K Venkatesh Denise M Harnois Michael R Charlton Hiroyuki Yamada Alicia Algeciras-Schimnich Melissa R Snyder Terry M Therneau Lewis R Roberts | 2018 | World Journal of Gastroenterology2018，24，12： | 5 |
| 3 | 免疫组化标记结果显示纤维板层肝癌具有肝细胞和胆管细胞分化特征显示文摘 | Ward S C Huang J Tickoo S K 樊祥山(摘译) | 2010 | 临床与实验病理学杂志2010，26，5： | 3 |
| 4 | Synthetic seismograms,a finite difference approach显示文摘 | Kelly K R Ward R W Treiter S | 1976 | Geophysics1976，41，1： | 2 |
| 5 | Interstitial cells of Cajal and electrical activity in ganglionic and aganglionic colons of mice显示文摘 | Ward S M G ershon M D Keef K | 2002 | Am J Physiol2002，283，2： | 2 |
| 6 | Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study显示文摘 | Julia Granerod Helen E Ambrose Nicholas WS Davies Jonathan P Clewley Amanda L Walsh Dilys Morgan Richard Cunningham Mark Zuckerman Ken J Mutton Tom Solomon Katherine N Ward Michael PT Lunn Sarosh R Irani Angela Vincent David WG Brown Natasha S Crowcroft | 2010 | The Lancet Infectious Diseases2010，，12： | 2 |
| 7 | Synthetic seismograms, a finite difference approach显示文摘 | Kelly K R Ward R W Treitel S | 1976 | Geophysics1976，41，： | 2 |
| 8 | Multiple evolutionary origins of knockdown resistance ( kdr ) in pyrethroid-resistant Colorado potato beetle, Leptinotarsa decemlineata显示文摘 | Frank D. Rinkevich Cathy Su Tomás A. Lazo David J. Hawthorne Ward M. Tingey Samir Naimov Jeffrey G. Scott | 2012 | Pesticide Biochemistry and Physiology2012，，3： | 2 |
| 9 | Paternal smoking, genetic polyrnorphisms in CYP1A1 and childhood leukemia risk 显示文摘 | Lee K M Ward M H Han S | 2009 | Leukemia Res2009，33，2： | 1 |
| 10 | Prospects for expanded utilization of biogas in Germany显示文摘 | POESCHL M WARD S OWENDE P | 2010 | Renewable and Sustainable Energy Reviews2010，14，7： | 1 |
| 11 | Micro T-mixer as a rapid mixing micromixer 显示文摘 | WONG S H WARD M C L WHARTON C W | 2004 | Sensors and Actuators B-Chemical2004，100，3： | 1 |
| 12 | Electromagnetic fields about a loop source of current显示文摘 | Ryu J Morrison F H Ward S H | 1970 | Geophysics1970，35，： | 1 |
| 13 | Influence of a lignin based admixture on the hydration of portland cements显示文摘 | KHALIL S M WARD M A | 1973 | Cem Concr Res1973，3，6： | 1 |
| 14 | Stearoyl-CoA desaturase mRNA is transcribed from a single gene in the ovine genome显示文摘 | WARD R J TRAVERS M T RICHARDS S E | 1998 | Biochim Biophys Acta1998，1391，： | 1 |
| 15 | Pneumonia: high-resolu tion CT findings in 114 patients显示文摘 | Reittner P Ward S Heyneman L | 2003 | Eur Radiol2003，13，3： | 1 |
| 16 | Clinical Importance of Delays in the Initiation of Appropriate Antibiotic Treatment for Ventilator-associated Pneumonia显示文摘 | Iregui M Ward S Sherman G | 2002 | Chest2002，122，1： | 1 |
| 17 | Sudden productivity collapse associated with the triassic- jurassic boundary mass extinction显示文摘 | Ward P D Haggart J W Carter E S | 2001 | Science2001，292，： | 1 |
| 18 | Exposure assessment of mycotoxins in dairy milk 显示文摘 | Coffey R Cummins E Ward S | 2009 | Food Control2009，20，3： | 1 |
| 19 | Progression of chronic renal failure on substituting a ketoacid supplement for anamino acid supplement显示文摘 | Walser M Hill S Ward L | | 0，，： | 1 |
| 20 | Discordant fetal leptin levels in monochorionic twins with chronic midtrimester twin-twin transfusion syndrome显示文摘 | Sooranna SR Ward S Bajoria R | | 0，，： | 1 |
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