|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Exosomal PD-L1 harbors active defense function to suppress T cell killing of breast cancer cells and promote tumor growth显示文摘 | Yi Yang Chia-Wei Li Li-Chuan Chan Yongkun Wei Jung-Mao Hsu Weiya Xia Jong-Ho Cha Junwei Hou Jennifer L. Hsu Linlin Sun Mien-Chie Hung | 2018 | Cell Research2018，28，8： | 35 |
| 2 | 淀粉粒分析揭示的江苏泗洪顺山集遗址古人类植物性食物来源与石器功能显示文摘淮河上中游地区位于中国东部南北过渡带,研究资料显示,淮河上游在距今约7000年前的新石器时代中期阶段,人类主要通过采集和农作物种植两种途径获取植物性食物资源,其农业模式为稻.旱(粟、黍)混作,而淮河中游地区同时期人类的植物性食物资源获取方式及其农业发展模式与上游地区是否相同,目前尚不清楚.顺山集遗址(约8500—7000aBP)是淮河中游地区目前所见年代最早的新石器时代遗址,本文选择该遗址出土的代表性石器圆形石球、石磨盘及石锤等石制工具17件及陶釜残片29件进行了淀粉粒残留物分析.结果显示,这些器物表面的古代淀粉粒主要来源于禾本科薏苡(Coix lacryma-jobi)、小麦族(Triticeae)、水稻(Oryza sativa.)、葫芦科栝楼(Trichosanthes kirilowii)根以及1种未知的植物种属.研究结果表明,淮河中游地区在距今7000年前的新石器时代中期,人类同样依靠采集和农业种植获取植物性食物资源,但与淮河上游地区不同的是,该区域的农业模式为稻作农业.值得注意的是,不同种属来源的淀粉粒在石器和陶器表面的出现频率分析结果表明,薏苡可能是顺山集先民主要的植物性食物来源,而水稻在当时的利用程度并不高.圆形石磨球、磨盘及长柱状石锤使用面上不同种类淀粉粒的发现表明这两类石器都曾被用于加工多种植物性食物,而石斧刃端发现丰富的植物淀粉粒,表明该类工具在当时除了用于砍斫工具以外,可能也曾被用来加工食物,其功能具有一器多用的特征.本文研究结果对了解顺山集先民的生业形式与出土石器的使用功能,探明淮河中游地区新石器时代早中期人类的植物资源利用与农业发展状况等问题具有重要的科学意义. | 杨玉璋 LI WeiYa 姚凌 程至杰 罗武宏 张居中 林留根 甘恢元 闫龙 | 2016 | 中国科学:地球科学2016，46，7： | 19 |
| 3 | Palmitoylation stabilizes PD-L1 to promote breast tumor growth显示文摘Dear Editor,PD-L1 is a well-known transmembrane protein, which is highly expressed on many types of cancer cells. By binding to its receptor PD-1 on T cells, PD-L1 significantly inhibits T cells activation and activity, and thus plays a pivotal role in driving the escape of tumor cells from immune surveillance.^1. | Yi Yang Jung-Mao Hsu Linlin Sun Li-Chuan Chan Chia-Wei Li Jennifer L. Hsu Yongkun Wei Weiya Xia Junwei Hou Yufan Qiu Mien-Chie Hung | 2019 | Cell Research2019，29，1： | 14 |
| 4 | The emergence, development and regional differences of mixed farming of rice and millet in the upper and middle Huai River Valley, China显示文摘Mixed farming of rice and millet is one of the basic agricultural modes in the upper and middle Huai River Valley(HRV). According to the latest data, this agricultural mode appeared during the middle and late Peiligang Culture(7.8–7.0 ka BP) in the upper HRV, and then became a common subsistence economy in the end of the Neolithic(5.0–4.0 ka BP) in both the upper and middle HRV. However, it is still not clear how this mixed farming developed in the upper HRV after its occurrence, nor are the regional differences in the development of mixed farming between the upper and middle HRV during the Neolithic completely understood. In this paper, flotation and starch analyses were conducted on samples from eight archaeological sites in the upper and middle HRV. The results indicate that the mixed farming of rice and millet first appeared in the later phase of the middle Neolithic in the regions of the Peiligang Culture, then developed quite rapidly in the late Neolithic(6.8–5.0 ka BP), finally becoming the main subsistence economy at the end of the Neolithic in the upper HRV. However, there are obvious differences in the emergence and development of agriculture between the middle and upper HRV. Rice farming was the only agricultural system during the middle Neolithic, lasting until the end of the Neolithic, when mixed farming appeared in the middle HRV. Furthermore, although mixed farming appeared in both the upper and middle HRV during the end of the Neolithic, the roles of rice, foxtail millet and broomcorn millet in the subsistence economy were not the same. In general, millet was more widely cultivated than rice in the upper HRV, but rice occupied the same or a slightly more prominent position in the middle HRV at the end of the Neolithic. These results are significant for understanding the process of agricultural development and transformation, as well as human adaptation to climatic and cultural variability duringthe Neolithic. | YANG YuZhang CHENG ZhiJie LI WeiYa YAO Ling LI ZhanYang LUO WuHong YUAN ZengJian ZHANG Juan ZHANG JuZhong | 2016 | Science China Earth Sciences2016，59，9： | 11 |
| 5 | A Nonlinear Control Algorithm for Flywheel Energy Storage Systems in Discharging Mode显示文摘针对Buck-Boost变换器的非线性特征给飞轮储能系统的放电运行状态带来的控制问题,提出了电压电流双环非线性控制算法。基于输入/输出线性化理论,推导出电流内环的控制律,并证明了内动态的稳定性。电压外环采用鲁棒性强的滑模变结构控制方法,并增加限流环节,保证放电电路安全、稳定运行。在Matlab/Simulink仿真平台中搭建飞轮放电模型,对所提出非线性控制算法进行了仿真验证。仿真结果表明,相比于双环PI控制,该算法能够明显改善输出电压调节时间、超调量等动态特性,在输入电压存在大范围变化的情况下,输出电压能够保持恒定和较低的纹波系数。 | WANG Nana Li Yongli ZHANG Weiya CHANG Xiaoyong XUE Wei | 2013 | 中国电机工程学报2013，33，19： | 11 |
| 6 | Plant food sources and stone tools' function at the site of Shunshanji based on starch grain analysis显示文摘The upper-middle Huai River valley(HRV) is located in the transition zone in the middle of eastern China. Previous studies have shown that the past populations in the upper HRV obtained plant food through gathering and cultivation of both rice and millet during the middle Neolithic. However, for the middle HRV it is not very clear what methods were used by humans to obtain plant food in that time. In this paper, starch grain analysis was carried out on 17 stone tools and 29 cauldron pottery sherds unearthed at Shunshanji(8.5–7.0 kyr BP), which is known as the earliest Neolithic site in the middle HRV excavated so far. Here, ancient starches from Coix lacryma-jobi, Triticeae, Oryza sativa, Trichosanthes kirilowii and one unidentified specie were recovered. This study contributes to the limited knowledge of food strategies as observed in the middle HRV. It demonstrates that both gathering and cultivation of rice took place during the middle-Neolithic. Among the identified species, Coix lacryma-jobi appears to have been the main plant food at Shunshanji. Moreover, it is clear that Oryza sativa was not consumed as much as other plant species according to the occurrence frequency of different starch grains. Starch grains were also found on the used surfaces of grinding stone implements as well as pestles, which means that these stone tools were used for food processing. In addition, axes from Shunshanji may also have been used for food processing as well as wood working because starches were also found on the edge of axes. Information about subsistence strategies and tool use at Shunshanji will also be helpful to understanding the utilization of plants and agricultural development in the middle HRV during the early-middle Neolithic period. | YANG YuZhang LI WeiYa YAO Ling CHENG ZhiJie LUO WuHong ZHANG JuZhong LIN LiuGen GAN HuiYuan YAN Long | 2016 | Science China Earth Sciences2016，59，8： | 9 |
| 7 | Analysis of Genetic Diversity and Differentiation of Seven Stocks of Litopenaeus vannamei Using Microsatellite Markers显示文摘Seven microsatellite markers were used to evaluate the genetic diversity and differentiation of seven stocks of Litopenaeus vannamei, which were introduced from Central and South America to China. All seven microsatellite loci were polymorphic, with polymorphism information content(PIC) values ranging from 0.593 to 0.952. Totally 92 alleles were identified, and the number of alleles(Na) and effective alleles(Ne) varied between 4 and 21 and 2.7 and 14.6, respectively. Observed heterozygosity(Ho) values were lower than the expected heterozygosity(He) values(0.526–0.754), which indicated that the seven stocks possessed a rich genetic diversity. Thirty-seven tests were detected for reasonable significant deviation from Hardy-Weinberg equilibrium. Fis values were positive at five loci, suggesting that there was a relatively high degree of inbreeding within stocks. Pairwise Fst values ranged from 0.0225 to 0.151, and most of the stock pairs were moderately differentiated. Genetic distance and cluster analysis using UPGMA revealed a close genetic relationship of L. vannamei between Pop2 and Pop3. AMOVA indicated that the genetic variation among stocks(11.3%) was much lower than that within stocks(88.7%). Although the seven stocks had a certain degree of genetic differentiation and a rich genetic diversity, there is an increasing risk of decreased performance due to inbreeding in subsequent generations. | ZHANG Kai WANG Weiji LI Weiya ZHANG Quanqi KONG Jie | 2014 | Journal of Ocean University of China2014，13，4： | 7 |
| 8 | La/Ce-codoped Bi_2O_3 composite photocatalysts with high photocatalytic performance in removal of high concentration dye显示文摘A series of La/Ce-codoped Bi_2O_3 composite photocatalysts were fabricated via hydrothermal–calcination process. The as-prepared products were intensively characterized by some physicochemical characterizations like N_2 physical adsorption, X-ray powder diffraction(XRD), scanning electron microscope(SEM), transmission electron microscope(TEM), UV–Vis diffuse reflectance(UV–Vis DRS), Fourier transform infrared spectroscopy(FT-IR),photoelectrochemical measurements, and photoluminescence(PL) spectroscopy. The characterization results indicated that La and Ce doping induced obvious crystal phase transformation in Bi_2O_3, from monoclinic to tetragonal phase. La and Ce codoping also gave rise to the obvious synergetic effects, e.g., the lattice contraction of Bi_2O_3, the decrease of crystal size and the increase of surface area. The photocatalytic performance of the prepared catalysts was evaluated by removal of dye acid orange II with high concentration under visible light irradiation. Results showed that La/Ce-codoped Bi_2O_3 displayed much higher photocatalytic performance than that of bare Bi_2O_3, single La or Ce doped Bi_2O_3 samples. The superior photocatalytic activity was mainly attributed to the improved texture and surface properties and the synergistic effects of La and Ce codoping on suppressing the recombination of photo-generated electrons(e^-) and holes(h^+). | Shuangshuang Xue Hongbo He Qizhe Fan Changlin Yu Kai Yang Weiya Huang Yang Zhou Yu Xie | 2017 | Journal of Environmental Sciences2017，29，10： | 7 |
| 9 | Identification of quantitative trait loci for four morphologic traits under water stress in rice (Oryza sativa L.)显示文摘Late season drought coinciding with the rice booting to heading stage affects the development of plant height, panicle exsertion, and flag leaf size, and causes significant yield loss. In this study, a recombinant inbred line population derived from a cross between paddy and upland cultivars was used for data collection of the morphologic traits under well water and drought stress conditions. Drought stress was applied at the stage of panicle initiation in the field in 2002 and at the booting stage in PVC pipes in 2003. The data from stress conditions and their ratios (trait measured under stress condition/trait measured under well water condition) or differences (trait measured under stress condition minus trait measured under well water condition) were used for QTL analysis. Totally, 17 and 36 QTLs for these traits were identified in 2002 and 2003, respectively, which explained a range of 2.58%-29.82% of the phenotypic variation. Among them, six QTLs were commonly identified in the two years, suggesting that the drought stress in the two years was different. The genetic basis of these traits will provide useful information for improving rice late season drought resistance, and their application as indirect indices in rice late season drought resistance screening was also discussed. | Bing Yue Weiya Xue Lijun Luo Yongzhong Xing | 2008 | Journal of Genetics and Genomics2008，35，9： | 7 |
| 10 | Joint Impacts of SSTA in Tropical Pacific and Indian Oceans on Variations of the WPSH显示文摘Using the NCEP/NCAR reanalysis and Had ISST sea surface temperature(SST) data, the joint effects of the tropical Indian Ocean and Pacific on variations of area of the summertime western Pacific subtropical high(WPSH) for period 1980–2016 are investigated. It is demonstrated that the central tropical Indian Ocean(CTI) and central equatorial Pacific(CEP) are two key oceanic regions that affect the summertime WPSH. During autumn and winter, warm SST anomalies(SSTAs) in CEP force the Walker circulation to change anomalously, resulting in divergence anomalies over the western Pacific and Maritime Continent(MC). Due to the Gill-type response, the abnormal anticyclonic circulation is generated over the western Pacific and South China Sea(SCS). In the subsequent spring, the warm SSTAs in CEP weaken, while the SST over CTI demonstrates a lagged response to Pacific SSTA. The warm CTISSTA and CEP-SSTA cooperate with the eastward propagation of cold Kelvin waves in the western Pacific, leading to the eastward shift of the abnormal divergence center that originally locates at the western Pacific and MC. The anticyclone forced by this divergence subsequently moves eastward, leading to the intensification of the negative vorticity there. Meanwhile, warm SSTA in CTI triggers eastward propagating Kelvin waves, which lead to easterly anomalies over the equatorial Indian Ocean and Indonesia, being favorable for maintenance and intensification of the anticyclone over the SCS and western Pacific. The monsoonal meridional–vertical circulation strengthens, which is favorable for the intensification of the WPSH. Using SSTA over the two key oceanic regions as predictors, a multiple regression model is successfully constructed for prediction of WPSH area. These results are useful for our better understanding the variation mechanisms of WPSH and better predicting summer climate in East Asia. | Daili QIAN Zhaoyong GUAN Weiya TANG | 2018 | Journal of Meteorological Research2018，32，4： | 6 |
| 11 | Highly stretchable pseudocapacitors based on buckled reticulate hybrid electrodes显示文摘以便与高特定的电容和突出的 stretchability 开发优秀 pseudocapacitor 与在便携的未来和 bio-implantable 系统适用的另外的设备匹配,我们在三个重要方面上集中我们的研究:混合电影电极,在不同部件之间的接口,和在基于围单人赛的碳 nanotube/polyaniline (SWCNT/PANI ) 的 supercapacitors 的 stretchability 和电气化学的综合性能的 Stretchability 预先伸长的弹性体上的合成电影。由于中等的孔,弄弯的混合电影避免裂开它发生在常规可拉长的混合电极,和两个 435 F | Nan Zhang Pingshan Luan Weiya Zhou Qiang Zhang Le Cai Xiao Zhang Wenbin Zhou Qingxia Fan Feng Yang Duan Zhao YanchunWang Sishen Xie | 2014 | Nano Research2014，7，11： | 4 |
| 12 | Erratum to: ZnO nanorods: morphology control, optical properties, and nanodevice applications [Sci China-Phys Mech Astron, 2013, 56: 2243–2265]显示文摘In the original publication of this paper,the affiliation and superscripted number relating to the current address of the authors has been documented incorrectly.The corrected information appears in this erratum. | ZHOU WeiYa ZHANG XiaoXian ZHAO Duan GAO Min XIE SiShen | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，9： | 3 |
| 13 | Mineralization Patterns and Conditions of Lateritic Gibbsite Bauxite in Guinea显示文摘After the exploration and research of Lateritic-Gibbsite bauxite for years in Guinea, based on factors such as paleoclimate, paleogeography and parent rocks, the laterization and bauxite mineralization process of lateritic gibbsite bauxite in Guinea were analyzed. The mineralization conditions and topography were favorable for the formation of bauxite deposits on the West Africa craton of NW Africa, especially in Guinea. Through chemical and phase analysis for mineralogy and petrology of different mining area in BOKE-SANGAREDI of Guinea, the mineralization characters of different minerals were analyzed. Due to the paleoclimate and paleogeographical conditions, the parent rocks were leached of certain major elements, such as Si, K, Na, Ca and Mg. However, some elements, such as Al, Fe, and Ti, became relatively concentrated. Based on composition analyses of the bauxite and surrounding rocks, the laterization and bauxite mineralization processes are evaluated in the Boke-Sangaredi area of Guinea. | Rongliang Zhang Enpu Gong Guoku Wang Weiya Peng | 2018 | Advances in Geoscience2018，2，1： | 2 |
| 14 | Optical visualization and polarized light absorption of the single-wall carbon nanotube to verify intrinsic thermal applications显示文摘The predicted extraordinary properties of carbon nanotubes(CNTs)from theoretical calculations have great potential for many applications.However,reliable experimental determination of intrinsic properties at the single-tube level is currently a matter of concern,and many challenges remain because of the unhandled and nanoscale size of individual nanotubes.Here,we demonstrated a prototype to detect the intrinsic thermal conductivity of the single-wall carbon nanotube(SWCNT)and verify the significant non-resonant optical absorption behavior on tiny nanotubes by integrating the nanotube and ice into a new core-shell design.In particular,a reversible optical visualization method based on the individual suspended ultra-long SWCNT was first developed by wrapping a nanotube with ice in the cryogenic air environment.The light-induced thermal effect on the hybrid core-shell structure was used tomelt the ice shell,which subsequently acted as a temperature sensor to verify the intrinsic thermal conductivity of the core-like nanotube.More interestingly,we successfully determined for the first time the thermal response phenomenon of the tiny absorption cross section in SWCNT in the vertical-polarization configuration and the significant non-resonant absorption behavior in the parallel-polarization configuration.These investigations will provide a better understanding for the unique optical behaviors of CNT and enable the detection of intrinsic properties of various one-dimensional nanostructures such as nanotubes,nanowires,and nanoribbons. | Xiao Zhang Li Song Le Cai Xuezeng Tian Qiang Zhang Xiaoying Qi Wenbin Zhou Nan Zhang Feng Yang Qingxia Fan Yanchun Wang Huaping Liu Xuedong Bai Weiya Zhou Sishen Xie | 2015 | Light(Science & Applications)2015，4，1： | 2 |
| 15 | Effects of AlN on the densification and mechanical properties of pressureless-sintered SiC ceramics显示文摘In the present work, Si C ceramics was fabricated with Al N using B_4 C and C as sintering aids by a solid-state pressureless-sintered method. The effects of Al N contents on the densification, mechanical properties, phase compositions, and microstructure evolutions of as-obtained Si C ceramics were thoroughly investigated. Al N was found to promote further densification of the Si C ceramics due to its evaporation over 1800 °C,transportation, and solidification in the pores resulted from Si C grain coarsening. The highest relative density of 99.65% was achieved for Si C sample with 15.0 wt% Al N by the pressureless-sintered method at 2130 °C for 1 h in Ar atmosphere. Furthermore, the fracture mechanism for Si C ceramics containing Al N tended to transfer from single transgranular fracture mode to both transgranular fracture and intergranular fracture modes when the sample with 30.0 wt% Al N sintered at 1900 °C for 1 h in Ar. Also, Si C ceramics with 30.0 wt% Al N exhibited the highest fracture toughness of 5.23 MPa m^(1/2) when sintered at 1900 °C. | Qisong Li Yujun Zhang Hongyu Gong Haibin Sun Yanxia Zhai Weiya Zhu Jie Jing | 2016 | Progress in Natural Science:Materials International2016，26，1： | 2 |
| 16 | Harnessing Knowledge from Maize and Rice Domestication for New Crop Breeding显示文摘Crop domestication has fundamentally altered the course of human history,causing a shift from huntergatherer to agricultural societies and stimulating the rise of modern civilization.A greater understanding of crop domestication would provide a theoretical basis for how we could improve current crops and develop new crops to deal with environmental challenges in a sustainable manner.Here,we provide a comprehensive summary of the similarities and differences in the domestication processes of maize and rice,two major staple food crops that feed the world.We propose that maize and rice might have evolved distinct genetic solutions toward domestication.Maize and rice domestication appears to be associated with distinct regulatory and evolutionary mechanisms.Rice domestication tended to select de novo,loss-of-function,coding variation,while maize domestication more frequently favored standing,gain-offunction,regulatory variation.At the gene network level,distinct genetic paths were used to acquire convergent phenotypes in maize and rice domestication,during which different central genes were utilized,orthologous genes played different evolutionary roles,and unique genes or regulatory modules were acquired for establishing new traits.Finally,we discuss how the knowledge gained from past domestication processes,together with emerging technologies,could be exploited to improve modern crop breeding and domesticate new crops to meet increasing human demands. | Qiuyue Chen Weiya Li Lubin Tan Feng Tian | 2021 | Molecular Plant2021，14，1： | 2 |
| 17 | The Crosstalk of mTOR/S6K1 and Hedgehog Pathways显示文摘 | Yan Wang Qingqing Ding Chia-Jui Yen Weiya Xia Julie G. Izzo Jing-Yu Lang Chia-Wei Li Jennifer L. Hsu Stephanie A. Miller Xuemei Wang Dung-Fang Lee Jung-Mao Hsu Longfei Huo Adam M. LaBaff Dongping Liu Tzu-Hsuan Huang Chien-Chen Lai Fuu-Jen Tsai Wei-Chao Ch | 2012 | Cancer Cell2012，，3： | 2 |
| 18 | The microRNA,miR-29c,participates in muscle development through targeting the YY1 gene and is associated with postmortem muscle pH in pigs显示文摘Previous studies indicated that miR-29c is important for muscle development in mice and human,but its role in pigs is unknown.In this study,we detected the expression of miR-29c in Meishan longissimus lumborum(LL)muscle.The results showed that miR-29c was gradually upregulated during development of skeletal muscle in pig.Moreover,the expression of YY1 and Akt3 genes,which were confirmed to be targeted by miR-29c in mice,was decreased along with muscle development.Furthermore,the expression level of miR-29c was significantly higher in adult Meishan pigs than Large White pigs,while the expression of YY1 and Akt3 genes was significantly lower in Meishan pigs.These results indicated that the expression pattern of miR-29c was opposite to that of YY1 and Akt3 genes in pigs.Also,the luciferase assay indicated that miR-29s can target the YY1 gene in pigs.In addition,we identified a T to C mutation in the primary transcript of miR-29c,which was associated with the postmortem muscle pH in pigs.Based on these results,we concluded that miR-29c is also important in skeletal muscle development of pigs. | Weiya ZHANG Wei WEI Yuanyuan ZHAO Shuhong ZHAO Xinyun LI | 2015 | Frontiers of Agricultural Science and Engineering2015，2，4： | 2 |
| 19 | Three-dimensional cellular automata based particle flow simulations of mechanical properties of talus deposit显示文摘Based on three-dimensional cellular automata (CA), a new stochastic simulation model to simulate the microstructures and particle flow of talus deposit is proposed. In addition, an auto-modeling program CARS is developed, with which numerical simulations can be conducted conveniently. For the problem of simulating mechanical behaviors of talus deposit, spatial arrangement or sphere shapes should be considered. In the new modeling method, four sphere arrangement models are developed for the particle flow simulation of talus deposit. Numerical results show that the talus deposit has the mechanical characteristics of typical stress-strain curves, as other rock-like materials. The cohesion of talus deposit decreases with increasing rock content, while the internal friction angle increases with increasing rock contents. Finally, numerical simulation is verified with the results of field test. | Linwei Wang Weiya Xu Anquan Xu | 2012 | Journal of Rock Mechanics and Geotechnical Engineering2012，4，4： | 2 |
| 20 | IκB Kinase Promotes Tumorigenesis through Inhibition of Forkhead FOXO3a显示文摘 | Mickey C.-T Hu Dung-Fang Lee Weiya Xia Leonard S Golfman Fu Ou-Yang Jer-Yen Yang Yiyu Zou Shilai Bao Norihisa Hanada Hitomi Saso Ryuji Kobayashi Mien-Chie Hung | 2004 | Cell2004，，2： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员