|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Trefoil factor-3 is not a useful marker of mucosal healing in Crohn's disease treated with anti-TNF-α antibodies显示文摘AIM To evaluate whether repeated serum measurements of trefoil factor-3(TFF-3)can reliably reflect mucosal healing(MH)in Crohn’s disease(CD)patients treated with anti-tumor necrosis factor-α(anti-TNF-α)antibodies.METHODS Serum TFF-3 was measured before and after antiTNF-αinduction therapy in 30 CD patients.The results were related to clinical,biochemical and endoscopic parameters.MH was defined as a≥50%decrease in Simple Endoscopic Score for Crohn’s disease(SES-CD).RESULTS SES-CD correlated significantly with CD clinical activity and several standard biochemical parameters(albumin,leukocyte and platelet counts,C-reactive protein,erythrocyte sedimentation rate,fibrinogen).In contrast,SES-CD did not correlate with TFF-3(P=0.54).Moreover,TFF-3 levels did not change significantly after therapy irrespectively of whether the patients achieved MH or not.Likewise,TFF-3 did not correlate with changes in fecal calprotectin,which has been proposed as another biochemical marker of mucosal damage in CD.CONCLUSION Serum TFF-3 is not a convenient and reliable surrogate marker of MH during therapy with TNF-αantagonists in CD. | Piotr Eder Kamila Stawczyk-Eder Katarzyna Korybalska Natasza Czepulis Joanna Luczak Liliana Lykowska-Szuber Iwona Krela-Kazmierczak Krzysztof Linke Janusz Witowski | 2017 | World Journal of Gastroenterology2017，23，1： | 3 |
| 2 | IL-17 stimu- lates intraperitoneal neutrophil infiltration through the release of GRO alpha chemokine from mesothelial cells 显示文摘 | Witowski J Pawlaczyk K Breborowicz A | 2000 | J Immunol2000，165，10： | 1 |
| 3 | StcE, a O157 : H7, specifically cleaves C1 esterase inhibitor 显示文摘 | Lathem WW Grys TE Witowski SE et metalloprotease secreted by Escherichia coli al | 2002 | Mol Microbiol2002，45，2： | 1 |
| 4 | Prolonged exposure to glucose degradation products impair viability and function of human peritoneal mesothelial cells显示文摘 | Witowski J Wisniewska J Korybalska K | 2001 | J Am Soc Nephrol2001，12，11： | 1 |
| 5 | IL-17 stimulates intraperitoneal neutrophil infiltration through the release of Croalpha chemokine from mesothelial cells显示文摘 | Witowski J Pawlaczyk K Brebarowicz A | 2000 | JImmunol2000，165，10： | 1 |
| 6 | IL-17 stim- ulates intraperitoneal neutrophil infiltration through the re-lease of Gro alpha chemokine from mesothelial cells 显示文摘 | Witowski J Pawlaczyk K Brebarowicz A | 2000 | J Immunol2000，165，10： | 1 |
| 7 | MEKK1 reg- ulates calpain - dependent proteolysis of focal adhesion proteins for rear - end detachment of migrating fi broblasts显示文摘 | CUEVAS B D ABELL A N WITOWSKY J A | 2003 | EMBO J2003，22，13： | 1 |
| 8 | Identification of IGFBP-7 by urinary proteomics as a novel prognostic marker in early acute kidney injury显示文摘 | Aregger F Uehlinger DE Witowski J | 2014 | Kidney Int2014，85，： | 1 |
| 9 | Far-infrared Magneto Absorption Studies of Zero-gap Hg1-xMnxSe Crystals显示文摘 | Witowski AM Furdyna JK | 1993 | Physical Review B1993，48，10： | 1 |
| 10 | Identification of IGFBP-7 by urinary proteomics as a novel prognostic marker in early acute kidney injury显示文摘 | Aregger F Uehlinger DE Witowski J | 2014 | Kidney Int2014，85，4： | 1 |
| 11 | Trace-level amino acid analysis by capillary liquid chromatography and application to in vivo microdialysis sampling with 10-stemporal resolution显示文摘 | Boyd BW Witowski SR Kennedy RT | 2000 | Anal Chem2000，72，4： | 1 |
| 12 | New developments in peritoneal fibroblast biology:implications for inflammation and fibrosis in peritoneal dialysis显示文摘 | Witowski J Kawka E Rudolf A | 2015 | Biomed Res Int2015，2015，13： | 1 |
| 13 | Evidence for less irritation to the peritoneal membrane in rats dialyzed with solutions low in glucose degradation products显示文摘 | Wieczorowska-Tobis K Brelinska R Witowski J | 2004 | Petit Dial Int2004，24，1： | 1 |
| 14 | Glucose-mediated induction of TGF-betal and MCP-1 in mesothelial cells in vitro is osmolality and polyol pathway dependent 显示文摘 | Wong T Y Phillips A O Witowski J | 2003 | Kidney Int2003，63，4： | 1 |
| 15 | Aquaporin water channels in water balance regulation in the kidney显示文摘 | Ksiazek K Witowski J | | 0，，12： | 1 |
| 16 | StcE, a metalloprotease secreted by Escherichia coli O157: H7, specifically cleaves CI esterase inhibitor 显示文摘 | Lathem W W Grys T E Witowski S E | 2002 | Mol Microbiol2002，45，2： | 1 |
| 17 | Acquisition of stcE, a C1 esterase inhibitor-specific metalloprotease, during the evolution of Escherichia coli O157:H7 显示文摘 | Lathem WW Bergsbaken T Witowski SE | 2003 | J Infect Dis2003，187，12： | 1 |
| 18 | Interleukin-17: a mediator of inflammatory responses 显示文摘 | Witowski J Ksiazek K Jones A | 2004 | Cell Mol Life Sci2004，61，5： | 1 |
| 19 | Interleukin-17: a mediator of inflammatory responses显示文摘 | Witowski J Ksiazek K Jorres A | 2004 | Cell Mol Life Sci2004，61，5： | 1 |
| 20 | The chemical vapour transport growth of ZnO single crystals 显示文摘 | Mycielski A Kowalczyk L Szadkowski A Chwalisz B Wysmoek A Baranowski J M Potemski M Witowski A Jaki R Barcz A Witkowska B Kaliszek W Jedrzejczak A Suchock A Lusakowska E Kaminska E | 2004 | Journal of Alloys and Compounds2004，371，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员