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| 1 | Finite-time Control of Linear Singular Systems with Parametric Uncertainties and Disturbances显示文摘The concept of finite-time stability for linear singular system is induced in this paper.Finite-time control problem is considered for linear singular systems with time-varying parametricuncertainties and exogenous disturbances. The disturbance satisfies a dynamical system with para-metric uncertainties. A su?cient condition is presented for robust finite-time stabilization via statefeedback. The condition is translated to a feasibility problem involving restricted linear matrix in-equalities (LMIs). A detailed solving method is proposed for the restricted linear matrix inequalities.Finally, an example is given to show the validity of the results. | FENGJun-E WUZhen SUNJia-Bing | 2005 | 自动化学报2005，31，4： | 28 |
| 2 | 体育学博士立足于国内培养之对策显示文摘通过对我国体育学博士培养历程的回顾和现状分析,提出了体育学博士立足于国内培养的基本对策,即:不断完善和健全体育学博士培养工作制度,大力加强博士生培养工作的硬件建设及导师梯队建设;积极争取较大幅度地扩大博士生培养规模;加强宣传,广辟生源。 | Tian Maijiu Zheng Wuzhen Huang Zhuhang(Beijing University of Physical Education,Beijing 100084) | 1996 | 北京体育大学学报1996，19，4： | 14 |
| 3 | FORWARD-BACKWARD STOCHASTIC DIFFERENTIAL EQUATIONS, LINEAR QUADRATIC STOCHASTIC OPTIMAL CONTROL AND NONZERO SUM DIFFERENTIAL GAMES显示文摘In this paper, we use the solutions of forward-backward stochastic differential equations to get the explicit form of the optimal control for linear quadratic stochastic optimal control problem and the open-loop Nash equilibrium point for nonzero sum differential games problem. We also discuss the solvability of the generalized Riccati equation system and give the linear feedback regulator for the optimal control problem using the solution of this kind of Riccati equation system. | WUZhen | 2005 | Journal of Systems Science & Complexity2005，18，2： | 13 |
| 4 | Phosphorylated extracellular signal-regulated kinase up-regulated p53 expression in shikonin-induced HeLa cell apoptosis显示文摘Background The role of extracellular signal-regulated kinase 1/2 (ERK1/2) in shikonin-induced HeLa cells apoptosis remains vague. This study was to investigate the activation of caspase pathways and the role of ERK1/2 in human cervical cancer cells, HeLa, by shikonin. Methods The inhibitory effect of shikonin on the growth of HeLa cells was measured by MTT assay. Fluorescent microscopic analysis of apoptotic cells stained with 4’,6’-oliiamiclino-2-phenylindole C (DAPI) and Hoechst 33258 was carried out. Caspase-3 and -8 activities were detected using caspase-3 substrate and caspase-8 substrate as substrates, respectively. The protein levels of ERK, p53 and p-ERK were determined by Western blot analysis.Results Shikonin inhibited cell growth in a time- and dose-dependent manner. Caspase-3 and caspase-8 were activated in the apoptotic process and caspase inhibitors effectively reversed shikonin-induced apoptosis. Phosphorylation of ERK resulted in up-regulation of p53 expression, which was blocked by mitogen-activated protein kinase (MEK), inhibitor PD 98059.Conclusion Shikonin induces HeLa cell apoptosis through the ERK, p53 and caspase pathways. | WUZhen WULi-jun TASHIROShinichi ONODERASatoshi IKEJIMATakashi | 2005 | Chinese Medical Journal2005，，8： | 13 |
| 5 | A portable viable Salmonella detection device based on microfluidic chip and recombinase aided amplification显示文摘creening of foodborne pathogens is important to prevent contaminated foods from their supply chains.n this study, a portable detection device was developed for rapid, sensitive and simple detection of viable almonella using a finger-actuated microfluidic chip and an improved recombinase aided amplification (RAA) assay. Improved propidium monoazide(PMAxx) was combined with RAA to enable this device to distinguish viable bacteria from dead ones. The modification of PMAxx into dead bacteria, the magnetic xtraction of nucleic acids from viable bacteria and the RAA detection of extracted nucleic acids were performed using the microfluidic chip on its supporting device by finger press-release operations. The fluorescent signal resulting from RAA amplification of the nucleic acids was collected using a USB camera nd analyzed using a self-developed smartphone App to quantitatively determine the bacterial concenration. This device could detect Salmonella typhimurium in spiked chicken meats from 1.3 × 10^(2) CFU/m L o 1.3 × 10^(7) CFU/m L in 2 h with a lower detection limit of 130 CFU/m L, and has shown its potential for on-site detection of foodborne pathogens. | Wuzhen Qi Siyuan Wang Lei Wang Xinge Xi Shangyi Wu Yanbin Li Ming Liao Jianhan Lin | 2023 | Chinese Chemical Letters2023，34，2： | 2 |
| 6 | γδT17 Cells Promote the Accumulation and Expansion of Myeloid-Derived Suppressor Cells in Human Colorectal Cancer显示文摘 | Pin Wu Dang Wu Chao Ni Jun Ye Wuzhen Chen Guoming Hu Zhen Wang Changrong Wang Zhigang Zhang Wenjie Xia Zhigang Chen Ke Wang Tao Zhang Jinghong Xu Yuehua Han Ting Zhang Xianguo Wu Jianwei Wang Weihua Gong Shu Zheng Fuming Qiu Jun Yan Jian Huang | 2014 | Immunity2014，，5： | 2 |
| 7 | Arabidopsis EXTRA-LARGE G PROTEIN 1(XLG1) functions together with XLG2 and XLG3 in PAMP-triggered MAPK activation and immunity显示文摘Pattern-triggered immunity(PTI) is an essential strategy used by plants to deploy broad-spectrum resistance against pathogen attacks. Heterotrimeric G proteins have been reported to contribute to PTI.Of the three non-canonical EXTRA-LARGE G PROTEINs(XLGs) in Arabidopsis thaliana, XLG2 and XLG3 were shown to positively regulate immunity,but XLG1 was not considered to function in defense,based on the analysis of a weak xlg1 allele.In this study, we characterized the xlg1 xlg2 xlg3 triple knockout mutants generated from an xlg1 knockout allele. The strong xlg1 xlg2 xlg3 triple mutants compromised pathogen-associated molecular pattern(PAMP)-triggered activation of mitogen-activated protein kinases(MAPKs) and resistance to pathogen infection. The three XLGs interacted with MAPK cascade proteins involved in defense signaling, including the MAPK kinase kinases MAPKKK3 and MAPKKK5, the MAPK kinases MKK4 and MKK5, and the MAPKs MPK3 and MPK6. Expressing a constitutively active form of MKK4 restored MAPK activation and partially recovered the compromised disease resistance seen in the strong xlg1 xlg2 xlg3 triple mutant. Furthermore, mutations of all three XLGs largely restored the phenotype of the autoimmunity mutant bak1-interacting receptor-like kinase 1. Our study reveals that all three XLGs function redundantly in PAMP-triggered MAPK activation and plant immunity. | Yiping Wang Hailei Zhang Pengxi Wang Huan Zhong Wuzhen Liu Shoudong Zhang Liming Xiong Yingying Wu Yiji Xia | 2023 | Journal of Integrative Plant Biology2023，65，3： | 1 |
| 8 | Visual tracking based on Distribution Fields and online weighted multiple instance learning 显示文摘 | NING Jifeng SHI Wuzhen YANG Shuqin | 2013 | Image and Vision Computing(S0262-8856)2013，31，11： | 1 |
| 9 | Preparation and pharmacokinetic study of fenofibrate cubic liquid crystalline显示文摘An LCC delivery system for Fenofibrate (Fen) was developed to improve its poorly oral bioavailability. Fen-LCC preparation methods were screened, and the prepared Fen-LCC was then characterized by a polarizing microscope and transmission electron microscopy (TEM).The spray drying technique was selected to dry and solidify particles into powder. The in vitro release of Fen-LCC was measured and in vivo pharmacokinetic experiments were carried out on rats after oral administration. Particles prepared through the high-temperature input method exhibited structural characteristics of LCC, and re-dissolved particles maintained the same features. The LCC delivery system can significantly improve in vitro release outcomes. After oral administration, AUCs of the suspension and LCC systems were measured at 131.6853 μg·h/ml and 1435.72893 μg·h/ml, respectively. The spray drying process presented here better maintains cubic structures, and the LCC system significantly improves bioavailability levels. | Shijie Wei Jingbo Ren Ning Li Wuzhen Huo Chongkai Gao | 2017 | Asian Journal of Pharmaceutical Sciences2017，12，6： | 1 |
| 10 | Visual Tracking with Online Multiple Instance Learning 显示文摘 | Ning Jifeng Shi Wuzhen Yang Shuqin | 2009 | Image and Vision Computing2009，31，11： | 1 |
| 11 | Modal analysis of serpentine belt drive systems显示文摘 | ZHANG Lixin ZU Wuzhen | 1999 | Journal of Sound and Vibration1999，222，2： | 1 |
| 12 | One-to-one auto-parametric resonance in serpentine belt drive systems显示文摘 | ZHANG Lixin ZU Wuzhen | 2000 | Journal of Sound andVibration2000，232，4： | 1 |
| 13 | Dynamics of a dry friction oscillator under two-frequency excitations显示文摘 | GONG Cheng ZU Wuzhen | 2004 | Journal of Sound andVibration2004，275，： | 1 |
| 14 | A lab-on-a-disc platform based on nickel nanowire net and smartphone imaging for rapid and automatic detection of foodborne bacteria显示文摘Foodborne pathogenic bacteria have been considered as a major risk factor for food safety. It is of great significance to carry out in-field screening of pathogenic bacteria to prevent the outbreaks of foodborne diseases. In this study, a portable lab-on-a-disc platform with a microfluidic disc was developed for rapid and automatic detection of Salmonella typhimurium using a nickel nanowire(Ni NW) net for effective separation of target bacteria, horseradish peroxidase nanoflowers(HRP NFs) for efficient amplification of biological signals, and a self-developed smartphone APP for accurate analysis of colorimetric images. First,the microfluidic disc was preloaded with reagents and samples and centrifuged to form one bacterial sample column, one immune Ni NW column, one HRP NF column, two washing buffer columns and one tetramethylbenzidine(TMB) column, which were separated by air gaps. Then, a rotatable magnetic field was specifically developed to assemble the Ni NWs into a net, which was automatically controlled by a stepped motor to successively pass through the sample column for specific capture of target bacteria, the HRP NF column for specific label of target bacteria, the washing columns for effective removal of sample background and non-specific binding NFs, and the TMB column for colorimetric determination of target bacteria. The color change of TMB from colorless to blue was finally analyzed using the smartphone APP to quantitatively determine the target bacteria. This lab-on-a-disc platform could detect Salmonella typhimurium from 5.6 × 10^(1) CFU/20 μL to 5.6 × 10^(5) CFU/20 μL in 1 h with a lower detection limit of 56 CFU/20 μL. The recovery of target bacteria in spiked chicken samples ranged from 97.5% to 101.8%. This portable platform integrating separation, labeling, washing, catalysis and detection onto a single disc is featured with automatic operation, fast reaction, and small size and has shown its potential for in-field detection of foodborne pathogens. | Xiaoting Huo Lei Wang Wuzhen Qi Na Rong Yingjia Liu Siyuan Wang Hong Duan Jianhan Lin | 2022 | Chinese Chemical Letters2022，33，4： | 0 |
| 15 | Diagnosis and Etiology of Secondary Infection of Escherichia coli with Rabbit Coccidiosis显示文摘In November 2012,diarrhea-predominant disease broke out in a large rabbit farm in Huaihua City,leading to mortality rate of 5. 3%. Through survey of incidence,combined with clinical symptoms,pathological changes and laboratory diagnosis,the disease was confirmed as secondary infection of E. coli with rabbit coccidiosis,and it had been controlled after drug treatment. | Luo Shimin Hu Hui Huang Guangzhong Su Wuzhen Yao Guomin Huang Minsheng Hu Yan | 2014 | Animal Husbandry and Feed Science2014，6，4： | 0 |
| 16 | Diagnosis and Etiological Analysis of Atypical Newcastle Disease in Mountain Forest Chickens in Huaihua City显示文摘The Newcastle disease is an acute infectious disease,which spreads rapidly and causes serious damage to the chicken industry.In recent years,due to various reasons,atypical,chronic Newcastle disease has appeared in several chicken farms,especially in the process of stocking in mountain forests.In this paper,the author analyzed the causes of atypical Newcastle disease occurred in mountain forest stocking chickens from a farm in Zhongfang County,Huaihua City,and proposed some control measures. | Wuzhen SU Hui HU Xiaoqin LIU Xu YANG Guangzhong HUANG | 2018 | Agricultural Biotechnology2018，7，6： | 0 |
| 17 | AN OPTION PRICING PROBLEM WITH THEUNDERLYING STOCK PAY1NG DIVIDENDS~显示文摘In this paper, a pricing problem of European call options is considered, wbete the underlying stock generates dividends d, at some fixed future dates T, before the expiration date T .without the inappropriate assumption made in that the dlvkdeMs being payed continously.The arbitrage free pricing of the option is determined via a series of partial differential equations.which is derived at the view point of backward s'tochasric differential ertuation (BBDE). It isshowed how the dividends affect the fair price of the call options. Some simulating results are alsogiven to illust rate the respective in fluence of parameters a.T.r,K.di and F1 on the option pricing. | XUWensheng Zhuangling WuZHEN | 1997 | Applied Mathematics(A Journal of Chinese Universities)1997，12，4： | 0 |
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