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29篇 您的检索式：作者名="Yaeger R"

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	题名	作者	年代	出处	被引量
1	BRAF突变提示转移性结直肠癌患者转移灶切除术后预后不良显示文摘BRAF突变发生于5%~11%的转移性结直肠癌患者。该研究分析了BRAF突变患者转移灶切除术后的临床病理因素、PIK3CA突变频率以及预后情况。研究通过回顾性的对2009年至2012年单中心1941例转移性结直肠癌患者行KRAS/BRAF突变检测,共检出92例患者含BRAF突变。2011年423例BRAF野生型转移性肠癌患者作为对照组。研究发现在转移性大肠癌中,与BRAF野生型组相比,BRAF突变型与确诊时高龄、女性、肿瘤位于右侧以及低分化、粘液组织形态更加相关。 BRAF突变更多出现于肠癌分期III期、T4期患者。 PIK3C与5%的BRAF突变共存,与17%的KRAS突变共存,与4%的BRAF/KRAS共突变共存。 BRAF突变的患者一般不只局限于肝转移,更容易出现腹膜转移。研究人员进一步研究发现合并BRAF突变的转移性肠癌患者转移灶相对不容易切除,即使切除后总生存期也较短。	Yaeger R Cercek A Chou JF	2014	中华结直肠疾病电子杂志2014，3，2：	13
2	Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer显示文摘	Misale S Yaeger R Hobor S	2012	Nature2012，486，7404：	1
3	Laboratory investigation of PRRS virus infection in three swine herds显示文摘	Zemen D Neiger R Yaeger M	1993	Vet Diagn Invest1993，5，：	1
4	Immunohistochemical evalu- ation of substance P and calcitonin gene-related peptide in skin and peri- osteum after extracorporeal shock wave therapy and radial pressure wave therapy in sheep显示文摘	Abed J M McClure S R Yaeger M J	2007	Am J Vet Res2007，68，3：	1
5	Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer显示文摘	Misale S Yaeger R Hobor S	2012	Nature2012，486，7404：	1
6	Emergence of KRASmutations and acquired resistance to anti 一 EGFR therapy in color-ectal cancer显示文摘	MISALE S YAEGER R HOBOR S	2012	Nature2012，486，7404：	1
7	Emergence of KRASmutations and acquired resistance to anti-EGFR therapy in color-ectal cancer显示文摘	MISALE S YAEGER R HOBOR S	2012	Nature2012，486，7404：	1
8	Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer显示文摘	Misale S Yaeger R Hobor S	2012	Nature2012，486，7404：	1
9	Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer 显示文摘	Misale S Yaeger R Hobor S	2012	Nature2012，486，7404：	1
10	Emergence of KRAS muta- tions and acquired resistance to anti-EGFR therapy in colorectal cancer 显示文摘	Misale S Yaeger R Hobor S	2012	Nature2012，486，7404：	1
11	Emergence ofKRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer显示文摘	Misale S Yaeger R Hobor S	2012	Nature2012，486，7404：	1
12	Genomic alterations observed in colitis - associated cancers are distinct from those found in sporadic colorectal cancers and vary by type of inflammatory bowel disease 显示文摘	YAEGER R SHAH M A MILLER V A	2016	Gastroenterology2016，，：	1
13	Impact of somatic mutations on patterns of metastasis in coloreetal cancer显示文摘	Lipsyc M Yaeger R	2015	J Gastrointest Oncol2015，6，6：	1
14	Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer显示文摘	Misale S Yaeger R Hobor S	2012	Nature2012，486，7404：	1
15	Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer 显示文摘	Misale S Yaeger R Hobor S	2012	Nature2012，486，7404：	1
16	Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer 显示文摘	Misale S Yaeger R Hobor S	2012	Nature2012，486，7404：	1
17	17β-HSD 2 may be higher in African-American breast cancer and is associated with estrogen receptor-negative tumors显示文摘	Yaeger R Nolan PC Su T	2007	Cancer Genomics Proteomics2007，4，5：	1
18	Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer 显示文摘	MISALE S YAEGER R HOBOR S	2012	Nature2012，486，7404：	1
19	Character-ization of an improved extraction chromatographic materi-al for the separation and preconcentration of strontium from acidic media显示文摘	DIETZ M L YAEGER J SAJDAK J L R	2005	Separation Science and Technology2005，40，：	1
20	Possible prevention of PMWS using inactivated PCV2 vaccine in CDCD pigs显示文摘	POGRANICHNIY R YOONL K-J YAEGER M	2004	Hamburg Germany:Proceedings of the 18th IPVS Congress2004，1，：	1

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