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| 1 | Interleukin-10 gene polymorphisms and hepatocellular carcinoma susceptibility:A meta-analysis显示文摘AIM: To assess the association between Interleu-kin-10 (IL-10) gene IL-10-1082 (G/A), IL-10-592(C/A), IL-10-819 (T/C) polymorphisms and hepatocellular carcinoma (HCC) susceptibility.METHODS: Two investigators independently searched the Medline, Embase, China National Knowledge Infrastructure, and Chinese Biomedicine Database. Summary odds ratios (ORs) and 95% conf idence intervals (95% CIs) for IL-10 polymorphisms and HCC were cal-culated in a fixed-effects model (the Mantel-Haenszel method) and a random-effects model (the DerSimonian and Laird method) when appropriate. RESULTS: This meta analysis included seven eligiblestudies, which included 1012 HCC cases and 2308 controls. Overall, IL-10-1082 G/A polymorphism was not associated with the risk of HCC (AA vs AG + GG, OR = 1.11, 95% CI = 0.90-1.37). When stratifying for ethnicity, the results were similar (Asian, OR = 1.12, 95% CI = 0.87-1.44; non-Asian, OR = 1.10, 95% CI = 0.75-1.60). In the overall analysis, the IL-10 polymorphism at position -592 (C/A) was identified as a genetic risk factor for HCC among Asians; patients carrying the IL-10-592*C allele had an increased risk of HCC (OR = 1.29, 95% CI = 1.12-1.49). No association was observed between the IL-10-819 T/C polymorphism and HCC susceptibility (TT vs TC + CC, OR = 1.02, 95% CI = 0.79-1.32).CONCLUSION: This meta-analysis suggests that IL-10-592 A/C polymorphism may be associated with HCC among Asians. IL-10-1082 G/A and IL-10-819 T/C polymorphisms were not detected to be related to the risk for HCC. | Yong-Gang Wei, Fei Liu, Bo Li, Xi Chen, Yu Ma, Lv-Nan Yan, Tian-Fu Wen, Ming-Qing Xu, Wen-Tao Wang, Jia-Yin YangYong-Gang Wei, Fei Liu, Bo Li, Xi Chen, Yu Ma, Lv-Nan Yan, Tian-Fu Wen, Ming-Qing Xu, Wen-Tao Wang, Jia-Yin Yang, Department of Liver and Vascular Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Prov- ince, China Author contributions: Wei YG and Liu F designed the study, collected and analyzed the data and wrote the manuscript Li B collected and analyzed the data and wrote the manuscript Chen X and Ma Y collected and analyzed the data Yan LN analyzed the data and contributed to the discussion Wen TF and Xu MQ revised the manuscript Wang WT and Yang JY contributed to the discussion Wei YG and Liu F contributed equally to this work. | 2011 | World Journal of Gastroenterology2011，17，34： | 3 |
| 2 | A preliminary validation of the Brief COPE instrument for assessing coping strategies among people living with HIV in China显示文摘Background:The Brief COPE instrument has been utilized to conduct research on various populations,including people living with HIV(PLWH).However,the questionnaire constructs when applied to PLWH have not been subjected to thorough factor validation.Methods:A total of 258 PLWH were recruited from two provinces of China.They answered questions involving the scales of three instruments:the Brief COPE,the Perceived Social Support Scale,and the Perceived Discrimination Scale for PLWH.Confirmatory factor analysis(CFA)and exploratory factor analysis(EFA)were conducted.Results:The CFA found a poor goodness of fit to the data.The subsequent EFA identified six preliminary factors,forming subscales with Cronbach’s alphas,which ranged from 0.61 to 0.80.Significant correlation coefficients between the subscales and measures of perceived social support and perceived discrimination were reported,giving preliminary support to the validity of the new empirical factor structure.Conclusion:This study showed that the original factor structure of the Brief COPE instrument,when applied to PLWH in China,did not fit the data.Thus,the Brief COPE should be applied to various populations and cultures with caution.The new factor structure established by the EFA is only preliminary and requires further validation. | Xiao-you Su Joseph TF Lau Winnie WS Mak KC Choi Tie-jian Feng Xi Chen Chu-liang Liu Jun Liu De Liu Lin Chen Jun-min Song Yan Zhang Guang-lu Zhao Zhang-ping Zhu Jin-quan Cheng | 2015 | Infectious Diseases of Poverty2015，4，1： | 2 |
| 3 | Protection of mice against gastric colonization by Helicobacter pylori by single oral dose immunization with attenuated Salmonella typhimurium producing urease subunits A and B 显示文摘 | Lucas B Yan ZX Panthel K Haas R Meyer TF | 1998 | Vaccine1998，16，5： | 1 |
| 4 | Scoring selection criteria includingtotal tumour volume and pretransplant percentage of lymphocytesto predict recurrence of hepatocellular carcinoma after liver trans-plantation 显示文摘 | Li C Wen TF Yan LN | 2013 | PLoS One2013，8，72： | 1 |
| 5 | Brassiere wearing and breast cancer risk:A systematic review and meta-analysis显示文摘AIM:To evaluate existing evidence for the association between different type of brassiere exposures and the risk of breast cancer.METHODS:Ovid Medline,CINAHL,Cochrane Data Base of Systematic Reviews,Pubmed,Scopus,Proquest,Sciencedirect,Wiley Online Library,WanF ang Data,Hong Kong Index to Chinese Periodicals,China Journal Net,Chinese Medical Current Contents,Chinese Biomedical Literature Database,China Academic Journals FullText database,Taiwan Electronic Periodical Services and HyR ead; reference lists of published studies; original research studies published in English or Chinese examining the association between type and duration of brassiere-wearing and breast cancer risk.Data were abstracted by a first reviewer and verified by a second.Study quality was rated according to predefined criteria.'Fair' or 'good' quality studies were included.Results were summarised by meta-analysis whenever adequate material was available.RESULTS:Twelve case-control studies were included in the review.Meta-analysis showed brassiere wearing during sleep was associated with a 1.3 times of increased risk.The odd ratio for more than 12 h of daily brassiere use in relation to breast cancer risk was 1.08(95%CI:1.01-1.14).CONCLUSION:The present review demonstrates insufficient evidence to establish a positive association between the duration and type of brassiere wearing and breast cancer.Further research is essential; specifically,a large-scale epidemiological study of a better design is needed to examine the association between various forms of brassiere exposure in detail and breast cancer risk,with adequate control of confounding variables. | Winnie KW So Dorothy NS Chan Yan Lou Kai-Chow Choi Carmen WH Chan Kristina Shin Ava Kwong Diana TF Lee | 2015 | World Journal of Meta-Analysis2015，3，4： | 1 |
| 6 | The implication of mineral coalescence behaviour on ash formation and ash deposition during pulverized coal combustion显示文摘 | Yan L Gupta RP Wall TF | 2001 | Fuel2001，，80： | 1 |
| 7 | Activation of dopamine D2 receptor is critical for the development of form deprivation myopia in the C57BL/6 mouse显示文摘 | Huang FR Yan TF Shi FJ | 2014 | Invest Ophthalmol Vis Sci2014，55，9： | 1 |
| 8 | Image segmentation by improved level set evolution algorithm 显示文摘 | Liu HY Yan TF ChengY | 2012 | Proceeding of the ~EE In~matiorml Conference on Information and Au- tomation2012，2012，： | 1 |
| 9 | Postoperativeneutrophil-to-lymphoeyteratioplus- pXatelet-to-lymphocyteratiopredicts the outcomes of hepatocellular carcinoma 显示文摘 | Li C Wen TF Yan LN | 2015 | J Surg Res2015，198，1： | 1 |
| 10 | Multiple forms of pymphosphate:D - fructose - 6 - phosphate 1 - phosphotransferase from wheat seedlings显示文摘 | Yan TF J Tao M | 1984 | J Biol Chem1984，259，： | 1 |
| 11 | Effect of botulinum toxin type A on cerebral palsy with upper limb spasticity显示文摘 | Yans TF Fu CP Kao NT | 2000 | Am Phps Med Rehabil2000，79，1： | 1 |
| 12 | Human age related cataracts: Epigenetic suppression of the nuclear factor erythroid 2 relat- ed factor 2 mediated antioxidant system显示文摘 | Gao YX Yan Y Huang TF | 2015 | Molecular Medi- cine Reports2015，11，2： | 1 |
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