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1Chinese expert consensus statement on the diagnosis and treatment of fulminant myocarditis显示文摘Fulminant myocarditis is primarily caused by infection with any number of a variety of viruses. It arises quickly, progresses rapidly, and may lead to severe heart failure or circulatory failure presenting as rapid-onset hypotension and cardiogenic shock,with mortality rates as high as 50%–70%. Most importantly, there are no treatment options, guidelines or an expert consensus statement. Here, we provide the first expert consensus, the Chinese Society of Cardiology Expert Consensus Statement on the Diagnosis and Treatment of Fulminant Myocarditis, based on data from our recent clinical trial(NCT03268642). In this statement, we describe the clinical features and diagnostic criteria of fulminant myocarditis, and importantly, for the first time,we describe a new treatment regimen termed life support-based comprehensive treatment regimen. The core content of this treatment regimen includes(i) mechanical life support(applications of mechanical respirators and circulatory support systems,including intraaortic balloon pump and extracorporeal membrane oxygenation),(ii) immunological modulation by using sufficient doses of glucocorticoid, immunoglobulin and(iii) antiviral reagents using neuraminidase inhibitor. The proper application of this treatment regimen may and has helped to save the lives of many patients with fulminant myocarditis.Daowen Wang Sheng Li Jiangang Jiang Jiangtao Yan Chunxia Zhao Yan Wang Yexin Ma Hesong Zeng Xiaomei Guo Hong Wang Jiarong Tang Houjuan Zuo Li Lin Guanglin Cui Section of Precision Medicine Group of Chinese Society of Cardiology,Editorial Board of Chinese Journal of Cardiology &Working Group of Adult Fulminant Myocarditis 2019Science China(Life Sciences)2019,62,2:18
2Evaluation of Typhoon Waves Simulated by Wave Watch-Ⅲ Model in Shallow Waters Around Zhoushan Islands显示文摘In this study, we simulated typhoon waves in the shallow waters around the Zhoushan Islands using the WaveWatch-Ⅲ(WW3) model version 5.16, the latest version released by the National Oceanic and Atmospheric Administration. Specifically, we used in-situ measurements to evaluate the performance of seven packages of input/dissipation source terms in the WW3 model. We forced the WW3 model by wind fields derived from a combination of the parametric Holland model and high-resolution European Center for Medium-Range Weather Forecasts(ECMWF) wind data in a 0.125? grid, herein called H-E winds. We trained the H-E winds by fitting a shape parameter B to buoy-measured observations, which resulted in a smallest root mean square error(RMSE) of 3 m s^(-1) for B, when treated as a constant 0.4. Then, we applied the seven input/dissipation terms of WW3, labelled ST1, ST2, ST2+STAB2, ST3, ST3+STAB3, ST4, and ST6, to simulate the significant wave height(SWH) up to 5 m during typhoons Fungwong and Chan-hom around the Zhoushan Islands. We then compared the SWHs of the simulated waves with those measured by the in-situ buoys. The results indicate that the simulation using ST2 performs best with an RMSE of 0.79 m for typhoon Fung-wong and an RMSE of 1.12 m for typhoon Chan-hom. Interestingly, we found the simulated SWH results to be relatively higher than those of the observations in the area between Hangzhou Bay and the Zhoushan Islands. This behavior is worthy of further investigation in the future.SHENG Yexin SHAO Weizeng LI Shuiqing ZHANG Yuming YANG Hongwei ZUO Juncheng 2019Journal of Ocean University of China2019,18,2:9
3Probing the limits of plasmonic enhancement using a two-dimensional atomic crystal probe显示文摘Achieving larger electromagnetic enhancement using a nanogap between neighboring metallic nanostructures has been long pursued for boosting light–matter interactions.However,the quantitative probing of this enhancement is hindered by the lack of a reliable experimental method for measuring the local fields within a subnanometer gap.Here,we use layered MoS2 as a two-dimensional atomic crystal probe in nanoparticle-on-mirror nanoantennas to measure the plasmonic enhancement in the gap by quantitative surface-enhanced Raman scattering.Our designs ensure that the probe filled in the gap has a well-defined lattice orientation and thickness,enabling independent extraction of the anisotropic field enhancements.We find that the field enhancement can be safely described by pure classical electromagnetic theory when the gap distance is no<1.24 nm.For a 0.62 nm gap,the probable emergence of quantum mechanical effects renders an average electric field enhancement of 114-fold,38.4%lower than classical predictions.Wen Chen Shunping Zhang Meng Kang Weikang Liu Zhenwei Ou Yang Li Yexin Zhang Zhiqiang Guan Hongxing Xu 2018Light(Science & Applications)2018,7,1:4
4Hydrogen Effects on the Mechanical Properties of Ti-24Al-11Nb-3V-1Mo Alloy显示文摘The effects of hydrogen on the mechanical properties at room temperature of a Ti3Al based alloy Ti-24Al-11Nb-3V-1Mo have been investigated. The results show a parabolic rate relationship between the average hydrogen concentration of the alloy at constant temperature and charging time. The mechanical properties (ultimate bending strength and deflection) decrease with increasing hydrogen content in the alloy. The fractographic feature indicates that the decrease of the mechanical properties is due to the crack nucleation and propagation at the hydrideChen, Yexin Wan, Xiaojing 1998Journal of Materials Science & Technology1998,14,2:3
5Evaluation of Wind Retrieval from Co-Polarization Gaofen-3 SAR Imagery Around China Seas显示文摘Gaofen-3(GF-3) is the first Chinese space-borne satellite to carry the C-band multi-polarization synthetic aperture radar(SAR). Marine applications, i.e., winds and waves retrieved from GF-3 SAR images, have been operational since January 2017. In this study, we have collected more than 1000 quad-polarization(vertical-vertical(VV); horizontal-horizontal(HH); vertical-horizontal(VH); horizontal-vertical(HV)) GF-3 SAR images, which were acquired around the China Seas from September 2016 to September 2017. Wind streaks were visible in these images in co-polarization(VV and HH) channel. Geophysical model functions(GMFs), including the CMOD5N together with polarization ratio(PR) model and C-SARMOD, were used to retrieve winds from the collected co-polarization GF-3 SAR images. Wind directions were directly obtained from GF-3 SAR images. Then, the SAR-derived wind speeds were compared with the measurements at a 0.25? grid from the Advanced Scatterometer on board the Metop-A/B and microwave radiometer WindSAT. Based on the analysis, empirical corrections are proposed to improve the performance of the two GMFs. Results of this study show that the standard deviation of wind speed is 1.63 m s^(-1) with a 0.19 m s^(-1) bias and 1.71 m s^(-1) with a 0.26 m s^(-1) bias for VV-and HH-polarization GF-3 SAR, respectively. Our work not only systematically evaluates wind retrieval by using the two advanced GMFs and PR models but also proposes empirical corrections to improve the accuracy of wind retrievals from GF-3 SAR images around the China Seas and thus enhance the accuracy of near real-time operational SAR-derived wind products.SHAO Weizeng ZHU Shuai SUN Jian YUAN Xinzhe SHENG Yexin ZHANG Qingjun JI Qiyan 2019Journal of Ocean University of China2019,18,1:3
6Geospatial technologies for Chang’e-3 and Chang’e-4 lunar rover missions显示文摘This paper presents a brief overview of the geospatial technologies developed and applied in Chang’e-3 and Chang’e-4 lunar rover missions.Photogrammetric mapping techniques were used to produce topographic products of the landing site with meter level resolution using orbital images before landing,and to produce centimeter-resolution topographic products in near real-time after landing.Visual positioning techniques were used to determine the locations of the two landers using descent images and orbital basemaps immediately after landing.During surface operations,visual-positioning-based rover localization was performed routinely at each waypoint using Navcam images.The topographic analysis and rover localization results directly supported waypoint-to-waypoint path planning,science target selection and scientific investigations.A GIS-based digital cartography system was also developed to support rover teleoperation.Kaichang Di Zhaoqin Liu Wenhui Wan Man Peng Bin Liu Yexin Wang Sheng Gou Zongyu Yue 2020Geo-Spatial Information Science2020,23,1:3
7Dual-channel type tunable field-effect transistors based on vertical bilayer WS2(1−x)Se2x/SnS2 heterostructures显示文摘Layered semiconductor heterostructures are essential elements in modern electronic and optoelectronic devices.Dynamically engineering the composition of these heterostructures may enable the flexible design of the properties of heterostructure-based electronics and optoelectronics as well as their optimization.Here,we report for the first time a two-step chemical vapor deposition approach for a series of WS2(1−x)Se2x/SnS2 vertical heterostructures with high-quality and large areas.The steady-state photoluminescence results exhibit an obvious composition-related quenching ratio,revealing a strong coherence between the band offset and the charge transfer efficiency at the junction interface.Based on the achieved heterostructures,dual-channel backgate field-effect transistors were successfully designed and exhibited typical composition-dependent transport behaviors,and pure n-type unipolar transistors to ambipolar transistors were realized in such systems.The direct vapor growth of these novel vertical WS2(1−x)Se2x/SnS2 heterostructures could offer an interesting system for probing new physical properties and provide a series of layered heterostructures for high-quality devices.Biyuan Zheng Dong Li Chenguang Zhu Jianyue Lan Xingxia Sun Weihao Zheng Huawei Liu Xuehong Zhang Xiaoli Zhu Yexin Feng Tao Xu Litao Sun Gengzhao Xu Xiao Wang Chao Ma Anlian Pan 2020InfoMat2020,2,4:3
8Validation of significant wave height retrieval from co-polarization Chinese Gaofen-3 SAR imagery using an improved algorithm显示文摘Chinese Gaofen-3(GF-3) is the first civilian satellite to carry C-band(5.3 GHz) synthetic aperture radar(SAR).During the period of August 2016 to December 2017, 1 523 GF-3 SAR images acquired in quad-polarization(vertical-vertical(VV), horizontal-horizontal(HH), vertical-horizontal(VH), and horizontal-vertical(HV)) mode were recorded, mostly around China's seas. In our previous study, the root mean square error(RMSE) of significant wave height(SWH) was found to be around 0.58 m when compared with retrieval results from a few GF-3 SAR images in co-polarization(VV and HH) with moored measurements by using an empirical algorithm CSAR_WAVE. We collected a number of sub-scenes from these 1 523 images in the co-polarization channel,which were collocated with wind and SWH data from the European Centre for Medium-Range Weather Forecasts(ECMWF) reanalysis field at a 0.125° grid. Through the collected dataset, an improved empirical wave retrieval algorithm for GF-3 SAR in co-polarization was tuned, herein denoted as CSAR_WAVE2. An additional 92 GF-3 SAR images were implemented in order to validate CSAR_WAVE2 against SWH from altimeter Jason-2, showing an about 0.52 m RMSE of SWH for co-polarization GF-3 SAR. Therefore, we conclude that the proposed empirical algorithm has a good performance for wave retrieval from GF-3 SAR images in co-polarization.SHENG Yexin SHAO Weizeng ZHU Shuai SUN Jian YUAN Xinzhe LI Shuiqing SHI Jian ZUO Juncheng 2018Acta Oceanologica Sinica2018,37,6:3
9Landing site topographic mapping and rover localization for Chang’e-4 mission显示文摘This paper presents the techniques and results of landing-site topographic mapping and rover localization using orbital,descent and rover images in the Chang’e-4 mission.High-resolution maps of the landing site are generated from orbital and descent images.Local digital elevation models and digital orthophoto maps with 0.02 m resolution are generated at each waypoint.The location of the lander is determined as(177.588?E,45.457?S)using festure-matching techniques.The cross-site visual localization method is routinely used to localize the rover at each waypoint to reduce error accumulation from wheel slippage and IMU drift in dead reckoning.After the first five lunar days,the rover travels 186.66 m from the lander,according to the cross-site visual localization.The developed methods and results have been directly utilized to support the mission’s operations.The maps and localization information are also valuable for supporting multiple scientific explorations of the landing site.Zhaoqin LIU Kaichang DI Jian LI Jianfeng XIE Xiaofeng CUI Luhua XI Wenhui WAN Man PENG Bin LIU Yexin WANG Sheng GOU Zongyu YUE Tianyi YU Lichun LI Jia WANG Chuankai LIU Xin XIN Mengna JIA Zheng BO Jia LIU Runzhi WANG Shengli NIU Kuan ZHANG Yi YOU Bing LIU Jiangang LIU 2020Science China(Information Sciences)2020,63,4:3
10Carboxyl groups trigger the activity of carbon nanotube catalysts for the oxygen reduction reaction and agar conversion显示文摘臭氧处理是到有象 carboxyl,酚和内酯一样的各种各样的氧功能的商业多围的碳 nanotubes (CNT ) 组织的 functionalize 的一条普通的路,以便提高他们的组织上性质和化学活动。以便详细说明每个功能的组的效果,我们相关有每个组的表面密度的活动,并且发现 carboxyl 组在二重要催化反应起一个枢轴的作用,也就是电气化学的氧减小反应( ORR )和到 5-hydroxymethylfurfural ( HMF )的琼脂变换。在这些过程期间,当改进的孔允许反应物和产品的有效散开时,吸水的表面为反应底层提供一种强壮的亲密关系。而且,为琼脂变换的 functionalized CNT 的活动在反应的九个周期期间仍然保持几乎未改变。这个工作为为电气化学的 ORR 和琼脂变换反应改进 CNT 的活动加亮策略,也是的 carboxyl 富有的 CNT 的有希望的应用生产高纯净的 HMFan 的稳固的酸催化剂重要化学中介。Yexin Zhang Chunlin Chen Lixia Peng Zhongsen Ma Yajie Zhang Hengheng Xia Aili Yang Lei Wang Dang Sheng Su Jian Zhang 2015Nano Research2015,8,2:2
11Ex vivo 3D osteocyte network construction with primary murine bone cells显示文摘Osteocytes reside as three-dimensionally(3D) networked cells in the lacunocanalicular structure of bones and regulate bone and mineral homeostasis. Despite of their important regulatory roles, in vitro studies of osteocytes have been challenging because:(1) current cell lines do not sufficiently represent the phenotypic features of mature osteocytes and(2) primary cells rapidly differentiate to osteoblasts upon isolation. In this study, we used a 3D perfusion culture approach to:(1) construct the 3D cellular network of primary murine osteocytes by biomimetic assembly with microbeads and(2) reproduce ex vivo the phenotype of primary murine osteocytes, for the first time to our best knowledge. In order to enable 3D construction with a sufficient number of viable cells, we used a proliferated osteoblastic population of healthy cells outgrown from digested bone chips. The diameter of microbeads was controlled to:(1) distribute and entrap cells within the interstitial spaces between the microbeads and(2) maintain average cell-to-cell distance to be about 19 mm. The entrapped cells formed a 3D cellular network by extending and connecting their processes through openings between the microbeads. Also, with increasing culture time, the entrapped cells exhibited the characteristic gene expressions(SOST and FGF23) and nonproliferative behavior of mature osteocytes. In contrast, 2D-cultured cells continued their osteoblastic differentiation and proliferation. This 3D biomimetic approach is expected to provide a new means of:(1) studying flow-induced shear stress on the mechanotransduction function of primary osteocytes,(2) studying physiological functions of 3D-networked osteocytes with in vitro convenience,and(3) developing clinically relevant human bone disease models.Qiaoling Sun Yexin Gu Wenting Zhang Leah Dziopa Jenny Zilberberg Woo Lee 2015Bone Research2015,3,3:2
12Sirolimus combined with oseltamivir and corticosteroid treatment for a puerpera with severe pneumonia caused by 2009 pandemic H1N1:A case report显示文摘Severe pneumonia in patients infected with the 2009 pandemic H1N1(pH1N1)virus was partially attributed to excessive immune response.Anti-virus treatment for these patients was insufficient.Here we reported the therapy effect of sirolimus,an immunosuppressor,combined with oseltamivir and corticosteroid for a puerpera with severe pneumonia caused by pH1N1 virus.This patient has infected with the pH1N1 virus in late pregnancy,and antiviral therapy was not implemented timely.She developed severe pneumonia and ARDS rapidly and need receive a cesarean section on the 39th week after pregnancy.After giving birth to a healthy baby,she received a combination of oseltamivir,sirolimus and corticosteroid,and improved in the following days.Moreover,the cytokines in serum and viral loads in BALF decreased significantly.She recovered without infectious symptoms and was discharged.Sirolimus combined with oseltamivir and corticosteroid is likely responsible for lowering the viral loads,reducing the patient's cytokine level,and further improving her clinical outcomes.It provides evidence that adjuvant treatment was beneficial to patients with severe pneumonia induced by the pH1N1 virus.Lijun Suo Xiaofeng Yu Yongfeng Hu Hongyun Cao Xiaohui Zou Peiquan Wang Tao Xu Xiangzhi Zhou Yexin Wu Lili Ren Bo Liu Bin Cao 2021Biosafety and Health2021,3,6:2
13An Automatic System of Vehicle Number-Plate Recognition Based on Neural Networks显示文摘This paper presents an automatic system of vehicle number-plate recognition based on neural networks. In this system, location of number-plate and recognition of characters in number-plate can be automatically completed. Pixel colors of Number-plate area are classified using neural network, then color features are extracted by analyzing scanning lines of the cross-section of number-plate. It takes full use of number-plate color features to locate numberplate. Characters in number-plate can be effectively recognized using the neural networks. Experimental results show that the correct rate of number.plate location is close to 100%, and the time of number-plate location is less than 1 second. Moreover, recognition rate of characters is improved due to the known number-plate type. It is also observed that this system is not sensitive to variations of weather, illumination and vehicle speed. In addition, and also the size of number-plate need not to be known in prior. This system is of crucial significance to apply and spread the automatic system of vehicle number-plate recognition.Wei Wu Dept. of Road and Traffic Engineering, Changsha Communications University, 410076, P. R. China Huang Xinhan, Wang Min & Song Yexin Dept. of Control Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, P. R. China 2001Journal of Systems Engineering and Electronics2001,12,2:2
14Possible change on the runoff in the upper Yellow River basin under global climate change显示文摘In this study,the characteristics and changing trends of temperature,precipitation,and runoff in the upper Yellow River basin up Tangnag station are analyzed by using hydrological and meteorological data in the past 50 years from observation stations in the basin.Further,in this study,the evolving trend of runoff in the future decades is forecasted in the basin based on the method of suppositional climate scenes combination.The results indicate temperature variation in the basin has an evident positive relation with global warming,and the precipitation variations are quite complicated in the basin because of differences of located geographic positions during the past 50 years.Runoff in the basin has been decreasing continually since the end of the 1980s because the mean temperature in the basin has been rising and precipitation in the main areas of runoff formation in the basin has been decreasing.Runoff will largely decrease if precipitation decreases and temperature rises continuously,whereas runoff will increase if temperature is invariable and precipitation increases largely;the increase magnitude of runoff may be more than that of precipitation because of the synchronously increasing supply of meltwater from snow,glacier,and frozen soils in future several decades.YongChao Lan Jun Wen JunJie Chang YeXin Xu YongPing Shen XingLin Hu JinQi Lu 2009Research in Cold and Arid Regions2009,1,2:2
15The Behavior of Hydrogen in High Temperature Titanium Alloy Ti - 60 显示文摘Chen Yexin Wan Xiaojing Li Fang 2007Mater Sci Eng A2007,466,:1
16Application of large cryo- genic helium system in large scientific facilities显示文摘QiuYinan Luo Yexin Zhang Ning 2011Vacuum & Cryo- genics2011,1,:1
17Effect of oxidative stress on ventricular arrhythmia in rabbits with adriamycin-induced cardiomyopathy显示文摘Li He Jianmin Xiao Hui Fu Guangsheng Du Xing Xiao Cuntai Zhang Ye Gu Yexin Ma 2012Journal of Huazhong University of Science and Technology2012,,3:1
18Complete logic functional- ity of reconfigurable RTD circuit elements显示文摘Zheng Yexin Huang Chao 2009IEEE Trans Nanotech2009,8,5:1
19Groundwa- ter quality and pollution evaluation in Xinjiang plain area 显示文摘J1 Yuanyuan ZHOU Jinlong GAO Yexin 2014WIT Transactions on Biomedicine and Health2014,8,:1
20Dietary Litsea cubeba essential oil supplementation improves growth performance and intestinal health of weaned piglets显示文摘This paper was to determine the effects of dietary Litsea cubeba essential oil(LEO)supplementation on growth performance,immune function,antioxidant level,intestinal morphology and microbial composition in weaned piglets.One hundred and ninety-two piglets(Duroc×[Large White×Landrace])with 6.85±0.22 kg mean body weight weaned at 21 d of age were randomly assigned to 4 treatment groups with 8 replicates and were fed with a basal diet(CON)or CON diet containing 100(LLEO),200(MLEO)and 400(HLEO)mg/kg LEO.The results revealed that HLEO supplementation(P<0.05)increased the average daily gain on d 28 compared with CON.MLEO and HLEO supplementation decreased(P<0.05)feed conversion ratio.LEO-containing diets had a lower(P<0.05)diarrhea rate.Supple-mentation with HLEO increased(P<0.05)total antioxidant capacity(T-AOC)both in the serum and liver.Meanwhile,the supplementation of MLEO and HLEO resulted in higher(P<0.05)glutathione peroxidase(GPx)activities both in serum and liver.Supplementation of HLEO increased(P<0.05)serum immu-noglobulin A,immunoglobulin G and interleukin-10,whereas supplementation with MLEO and HLEO decreased(P<0.05)tumor necrosis factor-α.Villus height in the duodenum or jejunum was increased(P<0.05)in the HLEO group,and the villus height to crypt depth ratio in the jejunum was also improved(P<0.05)in the MLEO group.The addition of LEO increased(P<0.05)the richness and diversity of the microbial community in the cecum,which mainly increased the relative abundance of Oscillospir-aceae_UCG-005,Faecalibacterium,Blautia and Coprococcus.Piglets supplemented with HLEO increased(P<0.05)the concentration of short chain fatty acids(SCFA),including acetic acid in the cecum and propionic acid in the colon.In conclusion,these findings indicated that LEO supplementation improved growth performance and intestinal health in weaned piglets.Zhe Yang Fang Wang Yexin Yin Peng Huang Qian Jiang Zhimou Liu Yulong Yin Jiashun Chen 2023Animal Nutrition2023,,2:1
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