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| 1 | Tumor differentiation phenotype in gastric differentiated-type tumors and its relation to tumor invasion and genetic alterations显示文摘瞄准:在胃的区分类型的肿瘤澄清在肿瘤区别显型和肿瘤侵略或基因改变之间的关系。方法:我们检验了肿瘤区别在 48 个胃的腺瘤和 171 区分类型的癌的显型,在 APC 和 p53 的变化的存在,和微卫星不稳定性(MSI ) 地位。肿瘤区别显型被检验人的表示决定胃粘蛋白(HGM ) , MUC6, MUC2 和 CD10。肿瘤然后被分类进胃 --(G-) ,胃、肠混合 --( 官方补给 --) ,或肠 --( 我 --) 显型,根据上述标记的免疫确实。在 APC 和 p53 和 MSI 地位的变化的存在也在所有肿瘤被调查。结果:胃的腺瘤显著地与 CD10 表示,我显型肿瘤和 APC 变化的存在被联系,与癌相比(66.7% 对 25.1% , P <
0.0001;56.3% 对 14.6% , P <
0.0001;39.6% 对 14.0% , P <
0.0001,分别地) 并且相反地与 HGM 和 MUC6 和 p53 变化的存在的表情联系了(10.4% 对 62.6% , P <
0.0001;39.6% 对 64.3% , P = 0.003;2.0% 对 26.3% , P = 0.001,分别地) 。APC 变化的频率在比在 HGM 积极的肿瘤, MUC6 积极的肿瘤, CD10 否定的肿瘤和 G 显型肿瘤的 HGM 否定的肿瘤, MUC6 否定的肿瘤, CD10 积极的肿瘤和我显型肿瘤是显著地更高的(32.7% 对 7.1% , P <
0.0001;27.8% 对 14.0% , P = 0.0182;37.3% 对 10.4% , P <
0.0001;并且 38.5% 对 9.5% , P = 0.0017,分别地) 。MSI 的频率在比在 MUC6 否定的肿瘤, CD10 积极的肿瘤和我显型肿瘤的 MUC6 积极的肿瘤, CD10 否定的肿瘤和 G 显型肿瘤是显著地更高的(24.8% 对 6.7% , P = 0.0009;22.2% 对 8.0% , P = 0.0143;并且 28.6% 对 9.6% , P = 0.0353,分别地) 。结论:肿瘤区别显型是仔细与在胃的区分类型的肿瘤的肿瘤侵略和基因改变有关。 | Kimiyasu Yamazaki Yusuke Tajima Reiko Makino Nobukazu Nishino Shigeo Aoki Masanori Kato Masaaki Sakamoto Koji Morohara Tsutomu Kaetsu Mitsuo Kusano | 2006 | World Journal of Gastroenterology2006，12，24： | 9 |
| 2 | Sentinel Node Mapping Guided by Indocyanine Green Fluorescence Imaging in Gastric Cancer显示文摘 | Yusuke Tajima Kimiyasu Yamazaki Yuki Masuda Masanori Kato Daisuke Yasuda Takeshi Aoki Takashi Kato Masahiko Murakami Mitsuharu Miwa Mitsuo Kusano | 2009 | Annals of Surgery2009，，1： | 3 |
| 3 | Risk Factors for Lymph Node Metastasis from Gastric Cancers with Submucosal Invasion显示文摘 | Yusuke Tajima Masahiko Murakami Kimiyasu Yamazaki Yuki Masuda Shigeo Aoki Masanori Kato Atsushi Sato Satoru Goto Koji Otsuka Takashi Kato | 2010 | Annals of Surgical Oncology2010，，6： | 2 |
| 4 | Sentinel Node Mapping Guided by Indocyanine Green Fluorescence Imaging in Gastric Cancer显示文摘 | Yusuke Tajima Kimiyasu Yamazaki Yuki Masuda Masanori Kato Daisuke Yasuda Takeshi Aoki Takashi Kato Masahiko Murakami Mitsuharu Miwa Mitsuo Kusano | 2009 | Annals of Surgery2009，，1： | 1 |
| 5 | Visualization of sphingolipids and phospholipids in the fundic gland mucosa of human stomach using imaging mass spectrometry显示文摘AIM:To analyze the lipid distribution in gastric mucosae.METHODS:Imaging mass spectrometry(MS)is a useful tool to survey the distribution of biomolecules in surgical specimens.Here we used the imaging MS apparatus named i MScope to identify the dominant molecules present in the human gastric mucosa near the fundic glands.Five gastric specimens were subjected to iM Scope analysis.These specimens were also analyzed by immunohistochemistry using MUC5 AC,H(+)-K(+)-ATPaseβ Claudin18 antibodies.RESULTS:Three major molecules with m/z 725.5,780.5,and 782.5 detected in the gastric mucosa were identified as sphingomyelin(SM)(d18:1/16:0),phosphatidylcholine(PC)(16:0/18:2),and PC(16:0/18:1),respectively,through MS/MS analyses.Using immunohistological staining,SM(d18:1/16:0)signals were mainly colocalized with the foveolar epithelium marker MUC5 AC.In contrast,PC(16:0/18:2)signals were observed in the region testing positive for the fundic gland marker H(+)-K(+)-ATPaseβ.PC(16:0/18:1)signals were uniformly distributed throughout the mucosa.CONCLUSION:Our basic data will contribute to the studies of lipid species in physical and pathological conditions of the human stomach. | Nobuya Kurabe Hisaki Igarashi Ippei Ohnishi Shogo Tajima Yusuke Inoue Yoshihiko Takahashi Mitsutoshi Setou Haruhiko Sugimura | 2016 | World Journal of Gastrointestinal Pathophysiology2016，7，2： | 1 |
| 6 | Scaling behavior of crowd flow outside a hall显示文摘 | Yusuke Tajima Takashi Nagatani | 2001 | Physica A: Statistical Mechanics and its Applications2001，，1： | 1 |
| 7 | Numerical simulation of nanoparticle pattern fabricated by electrostatic spray deposition显示文摘作为 patterning, nanoparticles 的方法在底层上扔了的 Electrospray 免职(ESD ) 由于超越另外的方法的几个优点吸引了许多注意。因为可靠数字模拟的缺乏,然而,获得为 nanoparticle 模式处理状况的最佳 ESD 就依靠试用实验。在这研究, electrospray 产生的 nanoparticle 的免职特征被使用一个三维的 Lagrangian 模型调查。包括解决方案电介质常数,三个重要进程参数在面具上使用了电压和表面电荷密度被修理 ESD 设备的几何参数考虑。模拟结果在条件下面显示出那没有一个面具,有增加溶剂电介质常数的水花直径增加,和更高应用的电压,使水花区域更宽。由在面具上改变表面电荷密度集中的可控制性被证实:面具上的更高的表面电荷密度导致更多的集中的免职。在这研究开发的数字模拟的有效性被比较与试验性的数据验证。 | Wei Wei Zhaolin Gu Sheng Wang Takeshi Fukuda Kiwamu Kase Jungmyoung Ju Yutaka Yamagata Yusuke Tajima | 2013 | Particuology2013，11，1： | 1 |
| 8 | Randomized phase II trial of first-line treatment with tailored irinotecan and S-1 therapy versus S-1 monotherapy for advanced or recurrent gastric carcinoma (JFMC31-0301)显示文摘 | Yoshito Komatsu Yutaka Takahashi Yutaka Kimura Hisashi Oda Yusuke Tajima Shigeyuki Tamura Jo Sakurai Takehiro Wakasugi Shigeru Tatebe Masahiro Takahashi Yuh Sakata Masaki Kitajima Junichi Sakamoto Shigetoyo Saji | 2011 | Anti-Cancer Drugs2011，，6： | 1 |
| 9 | A Comparative Study Between Flow Visualization and Computational Fluid Dynamic Analysis for the Sun Medical Centrifugal Blood Pump显示文摘 | Takashi Yamane ?Yusuke Miyamoto Koki Tajima | 2004 | Blackwell Publishing Artificial Organs2004，28，5： | 1 |
| 10 | Sentinel Node Mapping Guided by Indocyanine Green Fluorescence Imaging During Laparoscopic Surgery in Gastric Cancer显示文摘 | Yusuke Tajima Masahiko Murakami Kimiyasu Yamazaki Yuki Masuda Masanori Kato Atsushi Sato Satoru Goto Koji Otsuka Takashi Kato Mitsuo Kusano | 2010 | Annals of Surgical Oncology2010，，7： | 1 |
| 11 | Clogging transition of pedestrian flow in T-shaped channel 显示文摘 | Yusuke Tajima Takashi Nagatani | 2002 | Physica A2002，303，： | 1 |
| 12 | Scaling of pedestrian channel flow with a bottleneck显示文摘 | Yusuke Tajima Kouhei Takimoto Takashi Nagatani | 2001 | Physica A2001，294，： | 1 |
| 13 | Polymorphisms of GSTP1, ERCC2 and TS?3’UTR are associated with the clinicaloutcome of mFOLFOX6 in colorectal cancer patients显示文摘 | Kensuke Kumamoto Keiichiro Ishibashi Norimichi Okada Yusuke Tajima Kouki Kuwabara Yoichi Kumagai Hiroyuki Baba Norihiro Haga Hideyuki Ishida | 2013 | Oncology Letters2013，，3： | 1 |
| 14 | Control of Snow Falling Flow around NACA0015 Blade using a Plasma Electrode with Weather Resistant Design显示文摘The plasma actuation (PA) effect on the snow falling flow was investigated using a plasma electrode with weather resistant design and the natural snow wind facility of the Hokkaido University of Science. NACA0015 test blade with chord length c of 300 mm was used. Wind tunnel tests were carried out under the angle of the attack of the blade was fixed at 15 degrees, and the main flow velocity is U=5 m/s. PIV (Particle image velocimetry) measurements were conducted on various PA conditions using natural dry snowflakes as a tracer. When the actuator was driven under the condition of the fundamental frequency of F=50 kHz, and the pulsed modulated frequency f of fc/U=1 and Duty ratio (Ratio of plasma ON time to pulse duration time) =1%, movement of snowflakes was controlled the most effectively tested. It was clarified that the fundamental frequency of PA also affects the control of snow flow. Under snowfall conditions, the weather resistant designed plasma electrode has suffered no damage and operated successfully. | MATSUDA Hisashi CHIBA Takahiro YAGAMI Masaki TAJIMA Yusuke WATANABE Nobuyoshi SATO Hideaki TAKEYAMA Masafumi | 2022 | Journal of Thermal Science2022，31，1： | 0 |
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