|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Health risks associated with heavy metals in the drinking water of Swat,northern Pakistan显示文摘The concentrations of heavy metals such as Cd, Cr, Cu, Mn, Ni, Pb and Zn were investigated in drinking water sources(surface and groundwater) collected from Swat valley, Khyber Pakhtunkhwa, Pakistan. The potential health risks of heavy metals to the local population and their possible source apportionment were also studied. Heavy metal concentrations were analysed using atomic absorption spectrometer and compared with permissible limits set by Pakistan Environmental Protection Agency and World Health Organization. The concentrations of Cd, Cr, Ni and Pb were higher than their respective permissible limits, while Cu, Mn and Zn concentrations were observed within their respective limits. Health risk indicators such as chronic daily intake(CDI) and health risk index(HRI) were calculated for adults and children separately. CDIs and HRIs of heavy metals were found in the order of Cr > Mn >Ni > Zn > Cd > Cu > Pb and Cd > Ni > Mn > Cr > Cu > Pb > Zn, respectively. HRIs of selected heavy metals in the drinking water were less than 1, indicating no health risk to the local people. Multivariate and univariate statistical analyses showed that geologic and anthropogenic activities were the possible sources of water contamination with heavy metals in the study area. | Kifayatullah Khan Yonglong Lu Hizbullah Khan Shahida Zakir Ihsanullah Sardar Khan Akbar Ali Khan Luo Wei Tieyu Wang | 2013 | Journal of Environmental Sciences2013，25，10： | 12 |
| 2 | Development and characterization of an atorvastatin solid dispersion formulation using skimmed milk for improved oral bioavailability显示文摘Atorvastatin has low aqueous solubility resulting in low oral bioavailability(12%)and thus presents a challenge in formulating a suitable dosage form.To improve the aqueous solubility,a solid dispersion formulation of atorvasta tin was prepared by lyophilization utilising skimmed milk as a carrier.Six different formulations were prepared with varying ratios of drug and carrier and the corresponding physical mixtures were also prepared.The formation of a solid dispersion formulation was confirmed by differential scanning ca lorimetry and X-ray diffraction studies.The optimum drug-to-carrier ratio of 1:9 en hanced solubility nearly 33-fold as compared to pure drug.In vitro drug release studies exhibited a cumulative release of 83.69% as compared to 22.7% for the pure drug.Additionally,scanning electron microscopy studies suggested the conversion of crystalline atorvastatin to an amorphous form.In a Triton-induced hyperlipidemia model,a 3-fold increase in the lipid lowering potential was obtained with the reformulated drug as compared to pure drug.These results suggest that solid dispersion of atorvastatin using skimmed milk as carrier is a promising approach for oral delivery of atorvastatin. | Ankush Choudhary Avtar C.Rana Geeta Aggarwal Virender Kumar Foziyah Zakir | 2012 | Acta Pharmaceutica Sinica B2012，2，4： | 10 |
| 3 | 中、低收入国家卫生智囊团的实践影响政策变化显示文摘近年来,中、低收入国家独立卫生政策研究机构的数量与日俱增,原因在于政府研究能力有限和民主化进程中的压力。本研究的目标是:(1)调查中﹑低收入国家中卫生政策研究机构对卫生政策的议程设置﹑制定﹑执行、监管和评估所作的贡献;(2)评估包括组织形式和结构在内的哪些因素支持中﹑低收入国家的卫生政策研究机构对卫生政策发挥积极作用。本研究在孟加拉﹑加纳﹑印度﹑南非﹑乌干达和越南选取了6家卫生政策研究机构开展案例研究,研究对象包括两个非政府组织、两所大学和两个政府办政策研究机构。案例研究通过文献查阅、财务信息分析、对工作人员和其他利益相关人员进行半结构式访谈,以及对结论草案进行多次反馈等方式开展。其中有些机构对他们各自国家的政策发展作出了巨大贡献。这些机构都积极建言献策,多数从事与政策相关的研究,而开展政治对话﹑系统评价或委托性研究的机构则相对较少。这些机构所开展的工作大多以政府或出资人的需求为导向,多数机构的主要成果一般为研究报告,经常与面向政府官员的口头汇报相结合。在支持对政策的有效参与方面,有几个关键因素,其中包括支持性的政策环境﹑管理和财务的相对独立性,以及与决策者建立可增进信任和影响的密切关系。当研究机构与政府之间的正式关系未处在重要位置时,政府内部单位则面临相当大的困难。 | Sara Bennett Adrijana Corluka Jane Doherty Viroj Tangcharoensathlen Walaiporn Patcharanarumol Amar Jesani Joseph Kyabaggu Grace Namaganda A M Zakir Hussain Ama de-Graft Aikins | 2012 | 中国卫生政策研究2012，5，8： | 6 |
| 4 | Assessment of Heavy Metals in Grain Fields with Long-term Treatment of Agrochemicals and Organic Manure in Hailun City of Northeast China显示文摘Heavy metals were evaluated in the soils of grain fields in Hailun City Experimental Research Station--Chinese Academy of Sciences (CAS). Four categories of the soil samples were chosen from the fields after 19 years of treatment with chemicals, no fertilizer, organic manure, and organic manure combined with chemical fertilizer. The study revealed a prevalence of significantly high concentrations of Cu, Zn and Pb in organic manure combined with chemical fertilizer in the grain fields of black soils. The concentrations of Cu and Zn in no fertilizer treatment, chemical treatment, and organic treatment also exceeded the permissible limits. However, the concentrations of Hg and As were found to be within the safe limits in all treatments. | ZAKIR Shahidanasreen SHANG Zhanjiang XU Yanli ZHAN Lili LI Chunjie | 2011 | Journal of Northeast Agricultural University(English Edition)2011，18，2： | 4 |
| 5 | 氧化锌纳米颗粒对玉米储藏过程中微生物的抑制作用显示文摘玉米作为我国粮食储备的主要粮种之一,因其水分含量高、营养物质丰富、带菌量大等特点极易发生霉变、真菌毒素超标。本实验采用水热法优化制备了一种氧化锌纳米颗粒(zinc oxide nanoparticles,ZnO-NPs),以水为溶剂,n(Zn^(2+))∶n(OH^(-))为1∶8、水热温度120℃、恒温6 h条件下,制备的纳米颗粒为球形,采用动态光散射法测得ZnO-NPs的平均粒径为93 nm,多分散系数为0.024。X射线能谱分析、X射线衍射分析、傅里叶变换红外光谱分析等结果显示,所制备的纳米颗粒只含Zn和O两种元素,具有ZnO所特有的晶体结构和化学键特征。抑菌实验结果显示,所制备的ZnO-NPs对细菌和真菌有显著的抑制效果,玉米中添加ZnO-NPs后经过30 d的储藏,与对照组相比其菌落总数明显降低,且减缓了玉米品质劣变。研究结果表明,ZnO-NPs有助于抑制玉米储藏过程中的微生物繁殖,可为实现玉米长期安全储备过程中开发新的微生物抑制剂提供数据支撑。 | 张咚咚 胡思 Zakir HAYAT 宋慧玲 周显青 | 2021 | 食品科学2021，42，21： | 4 |
| 6 | Local site effects evaluation by surface wave and H/V survey methods in Senirkent(Isparta)region,southwestern Turkey显示文摘This study aimed to investigate the site characterization of the Senirkent Basin(Isparta)by using the microtremor(H/V)and surface wave analysis(ReMi)methods.Senirkent district,which is located on the foothill of the Kap?Mountain,are prone to seismic and landslide hazards.After the last landslip disaster(1995),the city has continued to develop on the alluvial basin.The microtremor data collected at 41 stations were analyzed.The predominant frequency and the amplification of the soil were found to be in the range of 1.8–6.6 Hz and 0.8–6.8,respectively.These are 4.0-6.8 Hz and 1-2.5 around the slope of the Kap?Mountain and 0.8-3.6 Hz and 3.0-6.6 at alluvium deposits of the valley.The ReMi data collected along 41 profiles were analyzed to obtain a Vs30 map.The soil classifications were done by using Vs30 values according to NEHRP soil classification criteria.The results showed that the southern area of the study had better soil conditions with Vs30 between 360-1160 m/s and soil class between C and B.The alluvium deposits on the north are relatively low with Vs30 in the range of 260-360 m/s and soil class D. | Mehmet Zakir Kanbur Ali Silahtar Gokhan Aktan | 2020 | Earthquake Engineering and Engineering Vibration2020，19，2： | 3 |
| 7 | Cardiac Troponins I and T: Molecular Markers for Early Diagnosis, Prognosis, and Accurate Triaging of Patients with Acute Myocardial Infarction显示文摘 | Ram P. Tiwari Anubhav Jain Zakir Khan Veena Kohli R. N. Bharmal S. Kartikeyan Prakash S. Bisen | 2012 | Molecular Diagnosis & Therapy2012，，6： | 3 |
| 8 | 平行平板间导电流体的磁流体动力学稳定性(英文)显示文摘采用Chebyshev配置点法研究平行平板间的导电流体在外加横向磁场作用下的动力稳定性.通过求解广义Orr-Sommerfeld方程的特征值问题,利用QZ法获取中性曲线,详细分析时间模式下磁流体线性稳定性,研究磁场Hartmann数、Reynolds数、波数和增长率对稳定性的作用. | Zakir Hussain 刘婵 倪明玖 张年梅 | 2013 | 中国科学院研究生院学报2013，30，3： | 3 |
| 9 | Untapped demand for heritage: A contingent valuation study of Prinsep Ghat, Calcutta显示文摘 | Mousumi Dutta Sarmila Banerjee Zakir Husain | 2005 | Tourism Management2005，，1： | 2 |
| 10 | Evaluation on Heavy Metals in Black Soils of Hailun and Bayan Counties in Northeast China显示文摘The concentration of heavy metals was investigated in black soil samples collected from the fields treated with chemical in Bayan County which were from the vegetation covers,bare soil and grain fields without any chemical treatments in Hailun National Field Research Station of Agroecosystem,Chinese Academy of Sciences (CAS) in July,2009.Results showed that the presence of significantly high concentration of zinc (Zn) and lead (Pb) in soils covered with grass vegetation.However,mercury (Hg),copper (Cu),nickel (Ni),cadmium (Cd),and arsenic (As) were found within the permissible limit set by international environmental agencies. | ZAKIR Shahidanasreen | 2010 | Journal of Northeast Agricultural University(English Edition)2010，17，2： | 2 |
| 11 | Microfold-cell targeted surface engineered polymeric nanoparticles for oral immunization显示文摘 | Basant Malik Amit K. Goyal T.S. Markandeywar Goutam Rath Foziyah Zakir Suresh P. Vyas | 2012 | Journal of Drug Targeting2012，，1： | 1 |
| 12 | Testing basic peKormance of a very small wind turbine designed for multi-purposes显示文摘 | HIROYUKI HIRAHARA M ZAKIR HOSSAIN MASAAKI KAWAHASHI | 2005 | Renewable Energy2005，30，88： | 1 |
| 13 | Experimental study of heat transfer of buried finned pipe for ground source heat pump applications 显示文摘 | Ahmet Koyun Hakan Demir Zakir Torun | 2009 | International Communications in Heat and Mass Transfer2009，36，7： | 1 |
| 14 | A functional clotting assay to monitor the hirudin dosage显示文摘 | Zakir RM Hoffman W Bhatt BA | 2007 | Blood Coagul Fibrinolysis2007，18，2： | 1 |
| 15 | Afferent innervation patterns of the saccule in pigeons显示文摘 | ZAKIR M HUSS D DICKMAN J D | 2003 | J Neuro physiol2003，89，： | 1 |
| 16 | Testing basic performance of a very small wind turbine designed for multpurposes显示文摘 | Hirahara Hiroyuki Hossain M Zakir Kawahashi Masaaki | 2005 | Renewable Energy2005，30，8： | 1 |
| 17 | Molecular mechanism of intestinal permeability : interaction at tight junctions 显示文摘 | Zakir H Takashi H | 2008 | The Royal Society of Chemistry2008，54，4： | 1 |
| 18 | Comparison of maleric anhydride grafting onto powder and granular polypropylene in the melt by reactive extrusion显示文摘 | GULDOGAN Y EGRI S ZAKIR M O | 2004 | Journal of Applied Polymer Science2004，92，6： | 1 |
| 19 | Water cost and water revenues for established and rain-induced roots of Agave deserti显示文摘 | HUNT E R ZAKIR J N J D NOBEL P S | 1987 | Functional Ecology1987，1，： | 1 |
| 20 | Pharmacokimetics and toxicity of intraperitoneal cisplatin combined with regional hyperthermia显示文摘 | Zakirs EL Dewhirst MW Riviere JE | 1987 | J Clin Oncol1987，5，10： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员