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| 1 | HPLC–MS and HPLC–MS/MS analysis of seven active constituents of Xiao-Xu-Ming decoction and application to a pharmacokinetic study after oral administration to rat显示文摘Xiao-xu-ming decoction(XXMD)is a traditional Chinese medicine that has been widely used to treat theoplegia and its sequelae.This paper reports the development of three separate assays based on reversed phase high-performance liquid chromatography–mass spectrometry(HPLC–MS)and HPLC–MS/MS for the determination of seven active constituents of XXMD viz oroxylin A-7-O-glucuronide,wogonoside,liquiritigenin,cimifugin,5-O-methylvisammiol,glycyrrhizic acid and glycyrrhetinic acid in rat plasma.All calibration curves were linear(r >0.99)with lower limits of quantitation(LLOQs)<12.4 ng/mL.Intra-and inter-day precisions(as relative standard deviation)were all <10.7% with recoveries in the range of 88.7–113%.In addition,the seven analytes were shown to be stable in rat plasma samples under relevant storage conditions.The validated methods were successfully applied to a pharmacokinetic study in rat after oral administration of XXMD. | Yilin Wang Chunguang Ding Caisheng Wu Kehe Du Jinlan Zhangn Hailin Qin Jinfeng Hou Guanhua Du | 2012 | Acta Pharmaceutica Sinica B2012，2，2： | 6 |
| 2 | PreventativeeffectsofGinkgobilobaextract(EGb761)onhighglucoseculturedopacityofratlens显示文摘 | LuQ YangT ZhangM DuL LiuL ZhangN etal | 2014 | PhytotherRes2014，28，5： | 1 |
| 3 | InvestigationofnitratepollutiningroundwaterduetonitrogenfertilizationinagricultureinnorthChina[J]显示文摘 | ZHANGWe山(张维理) TIANZhexu(回哲旭) ZHANGNing(张宁) etai | | 植物营养与肥料学报0，，： | 1 |
| 4 | Enhanced low tempera- ture performances of expanded commercial mesocarbon mi- crobeads (MCMB) as lithium ion battery anodes显示文摘 | Zhao G Y Wei Z H ZhangN Q | 2012 | Materials Letters2012，89，： | 1 |
| 5 | Geneticvariationsandpolymorphismsintheezringeneareassociatedwithagerelatedcataract显示文摘 | LinQ ZhouN ZhangN ZhuB HuS ZhouZ QiY | 2013 | MolVis2013，19，： | 1 |
| 6 | IntroductiontotheconceptchallengeofgenericdrugsresearchanddevelopmentandevaluationinChina显示文摘 | ZHANGN PINGQN | 2010 | 中国药学杂志2010，45，11： | 1 |
| 7 | Fffects of effects of water stresses on the expressions of functional genes, psbA, psbD and cab, for the photosystem II of different wheat varieties显示文摘 | LiuWJ YuanS ZhangN H | 2005 | 西北植物学报,2005,25(4):714-718.2005，25，4： | 1 |
| 8 | Enhanced photocatalytic activity of nanotube-like titania by sulfuric acid treatment显示文摘The TiO 2 nanotube sample was prepared via a NaOH solution in a Teflon vessel at 150℃. The as-prepared nanotubes were then treated with H 2SO 4 solutions. The TiO 2 nanotube has a crystalline structure with open-ended and multiwall morphologies. The TiO 2 nanotubes before and after surface acid treatment were characterized by X-ray diffraction(XRD), scanning electron microscopy(SEM), transmission electron microscopy(TEM) and UV-VIS dispersive energy spectrophotometry(DRS). The photocatalytic activity of the samples was evaluated by photocatalytic degradation of acid orange II in aqueous solutions. It was found that the order of photocatalytic activity was as follows: TiO 2 nanotubes treated with 1.0 mol/L H 2SO 4 solution (TiO 2(1.0M H 2SO 4) nanotubes)>TiO 2 nanotubes treated with 0.2 mol/L H 2SO 4 solution (TiO 2(0.2M H 2SO 4) nanotubes)>TiO 2 nanotubes >TiO 2 powder. This was attributed to the fact that TiO 2 nanotubes treated with H 2SO 4 was composed of smaller particles and had higher specific surface areas. Furthermore, the smaller TiO 2 particles were beneficial to the transfer and separation of photo-generated electrons and holes in the inner of and on the surface of TiO 2 particles and reduced the recombination of photo-generated electrons and holes. Acid treatment was particularly effective for TiO 2 nanotubes, this increase in activity was correlated with the concentration of H 2SO 4 solution. | YANGShao-gui QUANXie LIXin-yong FANGNing ZHANGNing ZHAOHui-min | 2005 | Journal of Environmental Sciences2005，17，2： | 1 |
| 9 | Evaluation of Cascade-Multilevel-Converter-Based STATCOM for Arc Furnace Fliker Mitigation显示文摘 | HAN Chong YANG Zhangning CHEN Bin | | 0，，02： | 1 |
| 10 | Scaling behavior in the web browser显示文摘 | ZHAOGengsheng(赵庚升) ZHANGNing(张宁) ZHOUTao(周涛) | 2009 | 统计与决策2009，27，7： | 1 |
| 11 | MicroRNA-100 promotes migration and invasion through mammalian target of rapamycin in esophageal squamous cell carcinoma显示文摘 | ZhangN FuH SongL | 2014 | Oncol Rep2014，32，14： | 1 |
| 12 | AdsorptionofgraGpheneoxide/chitosanporous materialsfor metalions显示文摘 | HeY Q ZhangN N WangX D | 2011 | ChineseChemL2011，22，7： | 1 |
| 13 | Amaizewall-associatedkinaseconfersquantitativeresistancetoheadsmut显示文摘 | ZuoW ChaoQ ZhangN etal | 2015 | NatGenet2015，47，2： | 1 |
| 14 | Field measurements of amplitude - dependent damping in a 79 - storey tall building and its effects on the structural dynamic responses 显示文摘 | Li Q S YangK ZhangN WongC K JearyA P | 2002 | Structural Design of Tall Buildings2002，11，2： | 1 |
| 15 | The effect of COD/N ratio on process performance and membrane fouling in a submerged bioreactor显示文摘 | FENGSP ZHANGN N LIU H C etal | 2012 | Desalination2012，285，： | 1 |
| 16 | Numerical simulation of cavity flow induced noise by LES and FW-H acoustic analogy 显示文摘 | ZHANGN SHEN H YAO H Z | 2010 | Journal of Hydrodynamics2010，22，5： | 1 |
| 17 | Preparation and thermal energy storage properties of paraffin/expanded graphite composite phase change material显示文摘 | ZHANG ZG ZHANGN PENGJ etal | 2012 | Applied Energy2012，91，1： | 1 |
| 18 | Clinical pharmacy 显示文摘 | WANGGF ZHANGNS SHENBY etal | 1980 | 中国药学杂志1980，15，4： | 1 |
| 19 | 显示文摘 | 陈丽(ChenL) 张宁(ZhangN) 高立军(GaoLJ) | 2011 | 南昌大学学报:理科版2011，35，： | 1 |
| 20 | Th22 in inflammatory and autoimmune dis-ease :prospects for therapeutic intervention 显示文摘 | ZhangN Pan HF Ye DQ | 2011 | Mol Cell Biochem2011，353，12： | 1 |
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