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1040篇 您的检索式：作者名="Zimmermann A"

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	题名	作者	年代	出处	被引量
1	Increased susceptibility for intrahepatic cholestasis of pregnancy and contraceptive-induced cholestasis in carriers of the 1331T>C polymorphism in the bile salt export pump显示文摘AIM: To study the association of three common ABCB11 and ABCC2 polymorphisms (ABCB11: 1331T>C V444A; ABCC2: 3563T>A V1188E and 4544G>A C1515Y) with intrahepatic cholestasis of pregnancy (ICP) and contraceptive-induced cholestasis (CIC). METHODS: ABCB11 and ABCC2 genotyping data were available from four CIC patients and from 42 and 33 ICP patients, respectively. Allele-frequencies of the studied polymorphisms were compared with those in healthy pregnant controls and Caucasian individuals. Furthermore, serum bile acid levels were correlated with the presence or absence of the 1331 C allele.RESULTS: The ABCB11 1331T>C polymorphism was significantly more frequent in cholestatic patients than in pregnant controls: C allele 76.2% (CI, 58.0-94.4) vs 51.3% (CI 35.8-66.7), respectively (P = 0.0007); and CC allele 57.1% (CI 36.0-78.3) vs 20% (CI 7.6-32.4), respectively (P = 0.0065). All four CIC patients were homozygous carriers of the C allele. In contrast, none of the studied ABCC2 polymorphism was overrepresented in ICP or CIC patients. Higher serum bile acid levels were found in carriers of the 1331CC genotype compared to carriers of the TT genotype.CONCLUSION: Our data support a role for the ABCB11 1331T>C polymorphism as a susceptibility factor for the ←←← development of estrogen-induced cholestasis, whereas no such association was found for ABCC2. Serum bile acid and γ-glutamyl transferase levels might help to distinguish ABCB4- and ABCB11-related forms of ICP and CIC.	Yvonne Meier Tina Zodan Carmen Lang Roland Zimmermann Gerd A Kullak-Ublick Peter J Meier Bruno Stieger Christiane Pauli-Magnus	2008	World Journal of Gastroenterology2008，14，1：	20
2	Connective tissue growth factor in human liver cirrhosis 显示文摘	Abou-Shady M Friess H Zimmermann A	2000	Liver2000，20，4：	1
3	Xylem water transport: is the available evidence consistent with the cohesion theory显示文摘	ZIMMERMANN U MEINZER F C BENKERT R ZHU J J SCHNEIDER H GOLDSTEIN G KUCHENBROD E HAASE A	1994	Plant Cell Environ1994，17，：	1
4	Interobserver a- greement of the TASC lI classification for supra- and infrain- guinal lesions显示文摘	Zimmermann A Wendorff H Schuster T	2010	Eur J Vasc Endovasc Surg2010，39，5：	1
5	Size separation of circulatory DNA in maternal plasma permits ready detection of fetal DNA polymorphisms显示文摘	Li Y Zimmermann B Rusterholz C Kang A Holzgreve W Hahn S	2004	Clin Chem2004，50，：	1
6	Predictive Habitat Distribution Models in Ecology显示文摘	Guisan A Zimmermann N E	2000	Ecological Modelling2000，135，：	1
7	Monolithic high-speed CMOS-photoreceiver显示文摘	H Zimmermann T Heide A Ghazi	1999	IEEE Photonics Technology Letters1999，11，2：	1
8	Increased expression of cytoskeletal, linkage, and extracellular proteins in failing human myocardium显示文摘	Heling A Zimmermann R Kostin S	2000	Circ Res2000，86，：	1
9	Functional and bi- ochemical evaluation of platelet aspirin resistance after coro- nary artery bypass surgery 显示文摘	Zimmermann N Wenk A Kim U	2003	Circulation2003，108，5：	1
10	Long-term results of five consecutive trials in childhood acute lymphoblastic leukemia performed by the ALL-BFM study group from 1981 to 2000显示文摘	Moricke A Zimmermann M Reiter A	2010	Leukemia2010，24，2：	1
11	Connective tissue growth factor in human liver cirrhosis显示文摘	Abou-Shady M Friess H Zimmermann A	2000	Liver2000，20，4：	1
12	Regulation of liver regeneration 显示文摘	Zimmermann A	2004	Neph rol Dial Transplant2004，194，：	1
13	Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase显示文摘	Haemmerle G Lass A Zimmermann R	2006	Science2006，312，5774：	1
14	In- flammation enhances car diova scular ri sk andmort alit y in hemo dialysi s 显示文摘	Zimmermann J Herrlinger S Pruy A	1999	Kidney Int1999，55，：	1
15	Mechanistically novel iron(III) transport system in Serratia marcescens 显示文摘	ZIMMERMANN L ANGERER A BRAUN V	1989	Journal of Bacteriology1989，171，：	1
16	Tuberculosis in the course of sarcoidosis treatment;is genotyping necessary for personalizedtherapy?显示文摘	Dubaniewicz A Zimmermann A Oudziak M et af	2013	Expert Eev Clin Immunol2013，9，4：	1
17	Mechanistically Novel Iron(Ⅲ) Transport System in Serratia Marcescens显示文摘	Zimmermann L Angerer A Braun V		0，，：	1
18	Assessment of primary cancers in growth hormone-treated adult hypopituitary patients:an analysis from the hypopituitary control and complications study (hypoccs)显示文摘	Child C Zimmermann A Woodmansee W		0，，02：	1
19	Heteronuclear dipolar recoupling in liquid crystals and solids by PISEMA-type pulse sequences显示文摘	Dvinskikh S V Zimmermann H Maliniak A	2003	J Magn Reson2003，164，1：	1
20	Predictive habitat distribution models in ecology显示文摘	GUISAN A ZIMMERMANN N E	2000	Ecological Modelling2000，135，：	1

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