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| 1 | Concurrent use of aromatase inhibitors and hypofractionated radiation therapy显示文摘AIM: To retrospectively assess the acute and long-term toxicity using aromatase inhibitors (AI) therapy concurrently with hypofractionated radiotherapy (HFRT) in breast cancer patients. METHODS: From November 1999 to October 2007, 66 patients were treated with breast HFRT and concurrent AI. In 63 patients (95.5%), HFRT delivered a total dose of 32.5 Gy to the whole breast within 5 wk (five fractions, one fraction per week). Other fractionations were chosen in three patients for the patients' personal convenience. A subsequent boost to the tumor bed was delivered in 35 patients (53.0%). Acute toxicities were scored according to the Common Toxicity Criteria for Adverse Events v3. Late toxicity was defined as any toxicity occurring more than 6 mo after completion of HFRT and was scored according to the Late Effects Normal Tissue Task Force-Subjective, Objective, Management and Analytic scale. RESULTS: At the end of the HFRT course, 19 patients (28.8%) had no irradiation-related toxicity. Acute grade 1-2 epithelitis was observed in 46 patients (69.7%). One grade 3 toxicity (1.5%) was observed. With a median follow-up of 34 mo (range: 12-94 mo), 31 patients (47%) had no toxicity, and 35 patients (53%) presented with grade 1-2 fibrosis. No grade 3 or greater delayed toxicity was observed. CONCLUSION: We found that AI was well tolerated when given concurrently with HFRT. All toxicities were mild to moderate, and no treatment disruption was necessary. Further prospective assessment is warranted. | Cyrus Chargari Pablo Castro-Pena Ivan Toledano Marc A Bollet Alexia Savignoni Paul Cottu Fatima Laki Franois Campana Patricia De Cremoux Alain Fourquet Youlia M Kirova | 2012 | World Journal of Radiology2012，4，7： | 2 |
| 2 | Assessment of genetic relatedness of the genera ananas and pseudananas confirmed by RAPD markers 显示文摘 | DE FATIMA RUASC RUSA P M | 2001 | Euphytica2001，119，： | 1 |
| 3 | Characteriza- tion of PAR1 and FGFR1 expression in invasive breast carcino- mas : Prognostic significance显示文摘 | Tiburcio M Costa SM DE Fatima Duarte M | 2012 | Oncol Lett2012，4，4： | 1 |
| 4 | Pulmonary artery diameters in healthy fetuses from 19 to 40 weeks' gestation显示文摘 | Ruano R de Fatima Yukie Maeda M Niigaki JI | 2007 | J Ultrasound Med2007，26，3： | 1 |
| 5 | Stroke and ischemic heart mortality trends in Brazil from 1979 to 1996 显示文摘 | De Padua Mansur A De Fatima Marinho Do Souza M | 2003 | Neuroepidemiology2003，22，3： | 1 |
| 6 | Fast and efficient microwave-assisted synthesis of functionalized peptoids via Ugi reactions显示文摘 | Angelica de Fatima S Barreto O Vercillo M | 2011 | Org Biomol Chem2011，9，16： | 1 |
| 7 | Remarkable effect of Co and Mn on the activity of Fe3-xMxO4 promoted oxidation of organic contaminants in aqueous medium with H2O2 显示文摘 | Costa R C C de Fatima M Lelis F Oliveira L C A Fabrls J D Ardisson J D Rios R R V A Silva C N Lago R M | 2003 | Catal Comm2003，4，10： | 1 |
| 8 | Development of a chemically modified electrode based on carbon paste and functionalized silica gel for preconcentration and voltammetric determination of mercury (Ⅱ)显示文摘 | ALEIXO L M DE FATIMA M SOUZA B | 1993 | Analytica Chimica Acta1993，271，1： | 1 |
| 9 | Evolution of X - ray machine quality controlaccep- tance indices显示文摘 | Maria Lucia Nana Maria de Fatima A Magon Yvone M Mas- carenhas | 2009 | Journal of Applied Clinical Medical Phys- ics2009，10，4： | 1 |
| 10 | Inositol 1,4,5-trisphosphate receptor in the liver:Expression and function显示文摘The liver is a complex organ that performs several functions to maintain homeostasis.These functions are modulated by calcium,a second messenger that regulates several intracellular events.In hepatocytes and cholangiocytes,which are the epithelial cell types in the liver,inositol 1,4,5-trisphosphate(InsP3)receptors(ITPR)are the only intracellular calcium release channels.Three isoforms of the ITPR have been described,named type 1,type 2 and type 3.These ITPR isoforms are differentially expressed in liver cells where they regulate distinct physiological functions.Changes in the expression level of these receptors correlate with several liver diseases and hepatic dysfunctions.In this review,we highlight how the expression level,modulation,and localization of ITPR isoforms in hepatocytes and cholangiocytes play a role in hepatic homeostasis and liver pathology. | Fernanda de Oliveira Lemos Rodrigo M Florentino Antonio Carlos Melo Lima Filho Marcone Loiola dos Santos M Fatima Leite | 2019 | World Journal of Gastroenterology2019，25，44： | 1 |
| 11 | Epigenetically reprogramming metastatic tumor cells with an embryonic microenvironment显示文摘 | Fabricio F Costa Elisabeth A Seftor Jared M Bischof Dawn A Kirschmann Luigi Strizzi Kelly Arndt Maria de Fatima Bonaldo Marcelo B Soares Mary JC Hendrix | 2009 | Epigenomics2009，，2： | 1 |
| 12 | Is it better to be rich in a poor area or poor in a rich area? A multilevel analysis of a case-control study of social determinants of tuberculosis 显示文摘 | de Alencar Ximenes RA de Fatima Pessoa Milita de Albuquerque M Souza WV | 2009 | Int J Epidemiol2009，38，5： | 1 |
| 13 | Remarkable effect of Co and Mn on the activity of Fe3-xMxO4 promoted Oxidation of organic contaminants in aqueous medium with H2O2 显示文摘 | Costa R C C De Fatima M Lelis F Oliveira L C A Fabris J D Ardisson J D Rios R R V A Silva C N Lago R M | 2003 | Catal Commun2003，4，10： | 1 |
| 14 | Remarkable effect of Co and Mn on the activity of Fe3-x MxO4 promoted oxidation of organic contaminants in aqueous medium with H2 O2 显示文摘 | Costa R C C De Fatima M Lelis F Oliveira L C A Fabris J D Ardisson J D Rios R R V A Silva C N Lago R M | 2003 | Catal Commun2003，4，10： | 1 |
| 15 | Comparison of perfusion, diffusion, and MR spectroscopy between low- grade enhancing pilocytic astrocytomas and high-grade astrocytomas显示文摘 | de Fatima Vasco Aragao M Law M Batista de Almeida D | 2014 | AJNR Am J Neuroradiol2014，35，8： | 1 |
| 16 | Stroke and ischemic heart disease mortality trends in Brazil from 1979 to 1996 显示文摘 | De Padua Mansur A De Fatima Marinho Do Souza M Iavarato D | 2003 | Neuroepidemiology2003，22，3： | 1 |
| 17 | Optic nerve infiltration by acute lymphoblastic leukernia-Mlcl contribution显示文摘 | de Fatima Soares M Braga IT da Rocha AJ Lederman HM | 2005 | Pediatr Radiol2005，35，8： | 1 |
| 18 | Nutritional intervention improves the caloric and proteic ingest- ion of head and neck cancer patients under radiotherapy显示文摘 | Goncalves Dias MC de Fatima Nunes Marucci M NadalinW | 2005 | Nutr Hosp2005，20，5： | 1 |
| 19 | Propranolol hydrochloride degradation using La@TiO_(2) functionalized with CMCD显示文摘Propranolol hydrochloride can be considered a persistent and bioaccumulative pharmaceutical in the environment.This drug and its by-products are potentially toxic and have adverse effects,since these compounds have been associated with endocrine-disrupting effects,reproductive deficiencies,embryo abnormalities and pericardial oedema.TiO_(2)–La 0.05%–carboxymethyl-β-cyclodextrin(CMCD)nanoparticles were successfully prepared by a simple two-step method,which consists of sonification and functionalization.The characterization analyses reveal that lanthanum is dispersed on the semiconductor surface,probably forming Ti–O–La bonds,which can induce oxygen vacancies and surface defects that effectively restrain the recombination of photogenerated electron/holes pairs.The efficiency of TiO_(2)–La 0.05%–CMCD samples in degradation of propranolol under UV-light irradiation is higher than that of pristine TiO_(2) within 20 min reaction,probably due to complex formation between theβ-blocker and the oligosaccharide,which allows us to propose a photocatalytic mechanism based on the formation of intermediates and competition of these compounds to the radicals and CMCD cavities. | Gustavo Lopes Colpani Vitor Follmann Santos Rubieli Carla Frezza Zeferino Micheli Zanetti Josiane Maria Muneron de Mello Luciano Luiz Silva Natan Padoin Regina de Fatima Peralta Muniz Moreira Márcio Antônio Fiori Cíntia Soaresc | 2022 | Journal of Rare Earths2022，40，4： | 0 |
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