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| 1 | Standard forward-viewing colonoscopy versus full-spectrum endoscopy: an international, multicentre, randomised, tandem colonoscopy trial显示文摘 | Ian M Gralnek Peter D Siersema Zamir Halpern Ori Segol Alaa Melhem Alain Suissa Erwin Santo Alan Sloyer Jay Fenster Leon M G Moons Vincent K Dik Ralph B D’Agostino Douglas K Rex | 2014 | Lancet Oncology2014，，3： | 6 |
| 2 | Role of human cy-tochrome P4501 Al,1A2, 1BI,and 3A4 in the 2-,4_,and 16-alpha-hydroxylation of 17 beta-estradioi显示文摘 | Alaa F B Ercole L C Eleanor G R | 2001 | Metabolism2001，50，9： | 1 |
| 3 | Effects of Foliar Application with Compost Tea and Filtrate Biogas Slurry Liquid on Yield and Fruit Quality of Washington Navel Orange (Citrus sinenesis Osbeck) Trees显示文摘 | Alaa K h Omar Elsayed B Belal Abd E1-Naiem | | 0，，07： | 1 |
| 4 | Effect of extraction solvent, waste fraction and grape variety on the antimicrobial and antioxidant activities of extracts from wine residue from cool climate显示文摘 | VERN J C ALAA E A B MICHELLE M | 2012 | Food Chemistry2012，134，： | 1 |
| 5 | Surgical outcome of pulmo- nary aspergilloma 显示文摘 | ALAA B ABDEL M S A1 RADY K | 2008 | Era' J Cardio-thoracic Surg2008，34，： | 1 |
| 6 | Spatial distribution and temporal trends of polycyclic aromat- ic hydrocarbons (PAHs) in sediments from lake ma- ryut, alexandria, egypt显示文摘 | Assem O B Alaa M Terry L Wade | 2011 | Water Air Soil Pollut2011，218，： | 1 |
| 7 | Type 2 diabetes mellitus and inflammation:prospects for biomarkers of risk and nutritional intervention显示文摘 | Alaa B Amira K Pierre H | 2010 | Canada:Diabetes Metab Syndr Obes2010，26，3： | 1 |
| 8 | Age-associated changes in the expression pattem of cyclooxygenase-2 and related apoptotic markers in the cancer suseptible region of rat prostate显示文摘 | Badawi Alaa F Liu Ying yin Eledden Mazen B | 2004 | Carcinogenesis2004，，9： | 1 |
| 9 | Could ephedrine replace meperidine for preven-tion of shivering in women undergoing Cesarean Section under spinalanesthesia? A randomized study 显示文摘 | Alaa ED Rafik B | 2012 | Egyptian Journal of Anaesthesi-a2012，，28： | 1 |
| 10 | An en- ergy-efficient threshold-based clustering protocol for wireless sensor networks显示文摘 | MOHAMMAD B AI-IMAD A K ALAA E A | 2013 | Wireless Personal Commtmications2013，70，1： | 1 |
| 11 | Up-and down-regulation of longissimus tenderness parallels changes in the myofibril-bound calpain 3 protein显示文摘 | Mohammad A I Alaa E1-Din A B Bradley S | 2004 | Meat Science2004，67，3： | 1 |
| 12 | Probabilistic lifetime assessment of RC structures under coupled corrosion-fatigue deterioration processes 显示文摘 | EMILIO B A PHILIPPE B ALAA C | 2009 | Struct Safety2009，31，： | 1 |
| 13 | Serum autoantibodies in patients with primary sclerosing cholangitis显示文摘 | Paul Angulo James B Peter M.Eric Gershwin Carolee K DeSotel Yehuda Shoenfeld Alaa E.E Ahmed Keith D Lindor | 2000 | Journal of Hepatology2000，，2： | 1 |
| 14 | Ligation of the Renal Vein During Laparoscopic Nephrectomy:An Effective And Reliable Method to Replace Vascular Staplers显示文摘 | GUNTER J FARIBORZ B ALAA A | 2003 | J Urol2003，170，： | 1 |
| 15 | Ligation of the renal vein during laparoscopic nephrectomy: An effective and reliable method to replace vascular staplers显示文摘 | Gunter J Fariborz B Alaa A | 2003 | J Urol2003，170，： | 1 |
| 16 | 虹膜色素剥脱综合征和剥脱性青光眼中血清维生素D水平分析(英文)显示文摘目的:虹膜色素剥脱综合征(XFS)和剥脱性青光眼(XFG)患者与对照组血清维生素D水平比较。方法:使用液相色谱法测量25羟基维生素D血清水平。记录性别、年龄、高血压、糖尿病和缺血性心脏病病史等可变因素。结果:研究包括55例XFS/XFG患者和正常对照组60例。XFS/XFG患者较为年长(平均年龄:71.8y vs 67.5y,P=0.002)。两组性别分布相似且糖尿病、高血压和缺血性心脏病的患病率无显著性差异。XFS/XFG患者平均维生素D水平为14.7 ng/mL,正常对照组为14.9 ng/mL,两组间无显著性差异。虽然XFS/XFG组维生素D水平较低,但在对年龄、性别和医疗条件进行校正后,多变量分析显示两组之间维生素D缺乏无显著差异。结论:XFS/XFG组和正常对照组维生素D水平均较低,而XFS/XFG组低于正常对照组,两组间无明显差异。XFS和维生素D缺乏症与某些系统性疾病有共同联系。 | Wisam A Shihadeh Mustafa R A1-Hashumi Mohammed B Khali Alaa Al-Dabbagh Majd Al-Shalakhti Saied A Jaradat Yousef Khader | 2018 | 国际眼科杂志2018，18，5： | 0 |
| 17 | The Screening of Diabetes, Obesity and Hypertension Risks Associated with Hepatitis C Within the Egyptian Population in a Community Pharmacy Setting显示文摘Background:Diabetes and hypertension have been identified as risk factors for HCV complications in previous studies.This has sparked the interest in the field of prevention by identifying at-risk individuals and increasing investments for screening among pharmacists.The aim of this study was to screen for risk factors,including age,gender,BMI,hypertension,diabetes,and obesity,in Egyptian patients with HCV Methods:A prospective cross-sectional study was carried out from September 2018 to February 2019,with a total of 1,959 medical records collected.By comparing the patients'characteristics,variables related to metabolic risk,and body composition measurements,regression models have been established to determine any confounding factors.Results:The prevalence of HCV antibody was 41.0%in men and 59.0%in women.Among the variables included in the regression analysis,age,BMI,and uncontrolled hypertension were found to have statistically significant associations with diabetes in HCV positive cases(p<0.001).HCV patients>40 years old with high BMI were found to have significant associations with both,diabetes and hypertension(p<0.001).Hypertensive HCV patients were found to have significant associations with gender,age>40,and DM(p<0.001).Conclusion:HCV infection and metabolic disorders have a closed cycle relationship.Reducing the complications of DM has a promising prospective of limiting the complications of HCV . | Amira B Kassem Mohamed EA Abdelrahim Alaa Mousa Amira Harun Heba Al-husseini Salma Khaled Mahmoud Elhadidy Osama Mohamed Ibrahim | 2022 | Journal of Clinical and Nursing Research2022，6，3： | 0 |
| 18 | Identification of functional tumor necrosis factor-alpha promoter variants associated with Helicobacter pylori infection in the Sudanese population: Computational approach显示文摘BACKGROUND Helicobacter pylori(H.pylori)is a ubiquitous bacterium that affects nearly half of the world’s population with a high morbidity and mortality rate.Polymorphisms within the tumor necrosis factor-alpha(TNF-A)promoter region are considered a possible genetic basis for this disease.AIM To functionally characterize the genetic variations in the TNF-A 5’-region(-584 to+107)of Sudanese patients infected with H.pylori using in silico tools.METHODS An observational study was carried out in major public and private hospitals in Khartoum state.A total of 122 gastric biopsies were taken from patients who had been referred for endoscopy.Genomic DNA was extracted.Genotyping of the TNF-A-1030 polymorphism was performed using PCR with confronting two-pair primer to investigate its association with the susceptibility to H.pylori infection in the Sudanese population.Furthermore,Sanger sequencing was applied to detect single nucleotide polymorphisms in the 5’-region(-584 to+107)of TNF-A in H.pylori-infected patients.Bioinformatics analyses were used to predict whether these mutations would alter transcription factor binding sites or composite regulatory elements in this region.A comparative profiling analysis was conducted in 11 species using the ECR browser and multiple-sequence local alignment and visualization search engine to investigate the possible conservation.Also,a multivariate logistic regression model was constructed to estimate odds ratios and their 95%confidence intervals for the association between TNF-A-1030,sociodemographic characteristics and H.pylori infection.Differences were statistically significant if P<0.05.Statistical analyses were performed using Stata version 11 software.RESULTS A total of seven single nucleotide polymorphisms were observed in the TNF-A 5’-region of Sudanese patients infected with H.pylori.Only one of them(T>A,-76)was located at the in silico-predicted promoter region(-146 to+10),and it was predicted to alter transcription factor binding sites and composite regulatory elements.A novel mutation(A>T,+27)was detected in the 5’untranslated region,and it could affect the post-transcriptional regulatory pathways.Genotyping of TNF-A-1030 showed a lack of significant association between-1030T and susceptibility to H.pylori and gastric cancer in the studied population(P=0.1756)and(P=0.8116),respectively.However,a significant association was detected between T/C genotype and H.pylori infection(39.34%vs 19.67%,odds ratio=2.69,95%confidence interval:1.17-6.17,P=0.020).Mammalian conservation was observed for the(-146 to+10)region in chimpanzee(99.4%),rhesus monkey(95.6%),cow(91.8%),domesticated dog(89.3%),mouse(84.3%),rat(82.4%)and opossum(78%).CONCLUSION Computational analysis was a valuable method for understanding TNF-A gene expression patterns and guiding further in vitro and in vivo experimental validation. | Abeer Babiker Idris Alaa B Idris Manal A Gumaa Mohammed Babiker Idris Amanda Elgoraish Mohamed Mansour Dalia Allam Bashir MO Arbab Nazar Beirag El-Amin M Ibrahim Mohamed A Hassan | 2022 | World Journal of Gastroenterology2022，28，2： | 0 |
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