|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Helicobacter pylori and oral pathology:Relationship with the gastric infection显示文摘Helicobacter pylori(H.pylori)has been found in the oral cavity and stomach,and its infection is one of the most frequent worldwide.We reviewed the literature and conducted a Topic Highlight,which identified studies reporting an association between H.pylori-infection in the oral cavity and H.pylori-positive stomach bacterium.This work was designed to determine whether H.pylori is the etiologic agent in periodontal disease,recurrent aphthous stomatitis(RAS),squamous cell carcinoma,burning and halitosis.Record selection focused on the highest quality studies and meta-analyses.We selected 48 articles reporting on the association between saliva and plaque and H.pylori-infection.In order to assess periodontal disease data,we included 12 clinical trials and 1 meta-analysis.We evaluated 13 published articles that addressed the potential association with RAS,and 6 with squamous cell carcinoma.Fourteen publications focused on our questions on burning and halitosis.There is a close relation between H.pylori infection in the oral cavity and the stomach.The mouth is the first extra-gastric reservoir.Regarding the role of H.pylori in the etiology of squamous cell carcinoma,no evidence is still available. | Isabel Adler Andrea Muio Silvia Aguas Laura Harada Mariana Diaz Adriana Lence Mario Labbrozzi Juan Manuel Muio Boris Elsner Alejandra Avagnina Valeria Denninghoff | 2014 | World Journal of Gastroenterology2014，20，29： | 21 |
| 2 | Small intestinal bacterial overgrowth in inactive Crohn's disease:Influence of thiopurine and biological treatment显示文摘AIM:To investigate the influence of thiopurines and biological drugs on the presence of small intestinal bacterial overgrowth(SIBO) in patients with inactive Crohn's disease(CD).METHODS:This was a prospective study in patients with CD in remission and without corticosteroid treatment,included consecutively from 2004 to 2010.SIBO was investigated using the hydrogen glucose breath test.RESULTS:One hundred and seven patients with CD in remission were included.Almost 58%of patients used maintenance immunosuppressant therapy and 19.6%used biological therapy.The prevalence of SIBO was16.8%.No association was observed between SIBO and the use of thiopurine Immunosuppressant(12/62patients),administration of biological drugs(2/21 patients),or with double treatment with an anti-tumor necrosis factor drugs plus thiopurine(1/13 patients).Half of the patients had symptoms that were suggestive of SIBO,though meteorism was the only symptom that was significantly associated with the presence of SIBO on univariate analysis(P<0.05).Multivariate analysis revealed that the presence of meteorism and a fistulizing pattern were associated with the presence of SIBO(P<0.05).CONCLUSION:Immunosuppressants and/or biological drugs do not induce SIBO in inactive CD.Fistulizing disease pattern and meteorism are associated with SIBO. | Cristina Sánchez-Montes Vicente Ortiz Guillermo Bastida Ester Rodríguez María Yago Belén Beltrán Mariam Aguas Marisa Iborra Vicente Garrigues Julio Ponce Pilar Nos | 2014 | World Journal of Gastroenterology2014，20，38： | 4 |
| 3 | Adalimumab in prevention of postoperative recurrence of Crohn's disease in high-risk patients显示文摘AIM:To evaluate the effectiveness of adalimumab in preventing recurrence after intestinal resection for Crohn's disease in high-risk patients.METHODS:A multicenter,prospective,observational study was conducted from June 2009 until June 2010.We consecutively included high-risk Crohn's disease patients who had undergone an ileal/ileocolonic resection.High-risk patients were defined as two or more criteria:smokers,penetrating pattern,one or more previous surgical resections or prior extensive resection.Subcutaneous adalimumab was administered 2 wk(± 5 d) after surgery at a dose of 40 mg eow,with an initial induction dose of 160/80 mg at weeks 0 and 2.Demographic data,previous and concomitant treatments(antibiotics,5-aminosalicylates,corticosteroids,immunomodulators or biologic therapies),smoking status at the time of diagnosis and after the index operation and number of previous resections(type and reason for surgery) were all recorded.Biological status was assessed with C-reactive protein,erythrocyte sedimentation rate and fecal calprotectin.One year(± 3 mo) after surgery,an ileocolonoscopy and/or magnetic resonance enterography was performed.Endoscopic recurrence was defined as Rutgeerts score ≥ i2.Morphological recurrence was based on magnetic resonance(MR) score ≥ MR1.RESULTS:Twenty-nine patients(55.2% males,48.3% smokers at diagnosis and 13.8% after the index operation),mean age 42.3 years and mean duration of the disease 13.8 years were included in the study.A mean of 1.76(range:1-4) resections previous to adalimumab administration and in 37.9% was considered extensive resection.51.7% had previously received infliximab.Immunomodulators were given concomitantly to 17.2% of patients.Four of the 29(13.7%) developed clinical recurrence,6/29(20.7%) endoscopic recurrence and 7/19(36.8%) morphological recurrence after 1-year.All patients with clinical recurrence showed endoscopic and morphological recurrence.A high degree of concordance was found between clinical-endoscopic recurrence(k = 0.76,P < 0.001) and clinical-morphological recurrence(k = 0.63,P = 0.003).Correlation between endoscopic and radiological findings was good(comparing the 5-point Rutgeerts score with the 4-point MR score,a score of i4 was classified as MR3,i3 as MR2,and i2-i1 as MR1)(P < 0.001,r s = 0.825).During follow-up,five(17.2%) patients needed adalimumab dose intensification(40 mg/wk);Mean time to intensification after the introduction of adalimumab treatment was 8 mo(range:5 to 11 mo).In three cases(10.3%),a biological change was needed due to a worsening of the disease after the dose intensification to 40 mg/wk.One patient suffered an adverse event.CONCLUSION:Adalimumab seems to be effective and safe in preventing postoperative recurrence in a selected group of patients who had undergone an intestinal resection for their CD. | Mariam Aguas Guillermo Bastida Elena Cerrillo Belén Beltrán Marisa Iborra Cristina Sánchez-Montes Fernando Muoz Jesús Barrio Sabino Riestra Pilar Nos | 2012 | World Journal of Gastroenterology2012，18，32： | 3 |
| 4 | Protocols implementing in a university hospital, an assessment of various methods 显示文摘 | Aguas CM Ports BM Delas AJ | 2004 | Farm Hosp2004，28，： | 1 |
| 5 | Are we ready for telemonitoring inflammatory bowel disease?A review of advances,enablers,and barriers显示文摘This review summarizes the evidence about telemonitoring in patients with inflammatory bowel disease(IBD). To give an overview of the advances performed, as well as the enablers and barriers which favoured/hindered telemonitoring implementation. We performed a literature search in Pub Med, EMBASE, MEDLINE, Cochrane Database, Web of Science and Conference Proceedings. Titles and abstracts published up to September 2022 were screened for a set of inclusion criteria: telemonitoring intervention, IBD as the main disease, and a primary study performed. Ninety-seven reports were selected for full review. Finally, 20 were included for data extraction and critical appraisal. Most studies used telemonitoring combined with tele-education, and programs evolved from home telemanagement systems towards web portals through m Health applications. Web systems demonstrated patients’ acceptance, improvement in quality of life, disease activity and knowledge, with a good cost-effectiveness profile in the short-term. Initially, telemonitoring was almost restricted to ulcerative colitis, but new patient reported outcome measures, home-based tests and mobile devices favoured its expansion to different patients’ categories. However, technological and knowledge advances led to legal, ethical, economical and logistic issues. Standardization of remote healthcare is necessary, to improve the interoperability of systems as well as to address liability concerns and users’ preferences. Telemonitoring IBD is well accepted and improves clinical outcomes at a lower cost in the short-term. Funders, policymakers, providers, and patients need to align their interests to overcome the emerging barriers for its full implementation. | Javier Del Hoyo Mónica Millán Alejandro Garrido-Marín Mariam Aguas | 2023 | World Journal of Gastroenterology2023，29，7： | 1 |
| 6 | Evaluation of the Treponema pallidu m particl agglutination technique(TPPA)in the diagnosis of neurosyphilis显示文摘 | Castro R Prieto ESJoao Aguas M | 2006 | J Clin Lab Anal2006，20，6： | 1 |
| 7 | Prevalence of irritable bowel syndrome (IBS)in first- degree relatives of patients with inflammatory bowel disease ( IBD ) 显示文摘 | Aguas M Garrigues V Bastida G | 2011 | J Crohns Colitis2011，5，3： | 1 |
| 8 | Evaluation of the treponema pallidum particle agglutination technique (TPPA) in the diagnosis of neurosyphilis显示文摘 | Castro R Pricto ES Aguas MJ | 2006 | J Clin Lab Anal2006，20，6： | 1 |
| 9 | Malignant transformation of atypical oral lichen planus: a review of 32 cases 显示文摘 | Lanfranchi-Tizeira HE Aguas SC Sano SM | 2003 | Med Oral2003，8，1： | 1 |
| 10 | Detailed arrangement of the bronchial arteries in the Wistar rat:A study using vascular injection and scanning electron microscopy显示文摘 | Ferrieira P G Silva A C Aguas A P | 2001 | Eur J Anat2001，5，2： | 1 |
| 11 | The coronary circulation of the pig heart : comparison with the human heart 显示文摘 | Aguas AP Grande NR Rodrigues M | 2005 | Eur J Anat2005，9，2： | 1 |
| 12 | The concept of life cycle: an application to the tourist product显示文摘 | Goncalves V F Aguas P M | 1997 | Journal of Travel Research1997，36，3： | 1 |
| 13 | Evaluation of tile Treponema pallidum particle agglutination technique (TPPA) in the diagnosis of neurosyphilis显示文摘 | Castro R Prieto ES Aguas MJ | 2006 | Clin Lab Anal2006，20，6： | 1 |
| 14 | Malignant transformation of Atypical Oral Lichen Planus: A review of 32 cases 显示文摘 | Quarracina MC Aguas SC | 2003 | Med Oral2003，8，1： | 1 |
| 15 | Benign adenomyoep-ithelioma of the breast: a case with gross mimicking of malignancy 显示文摘 | Felipo F Del Agua C Eguizabal C Vaquero M | 2002 | Breast J2002，，8： | 1 |
| 16 | Acute toxicity of pesticides to the tropical freshwater shrimp Caridina laevis 显示文摘 | David S Nico M Agua K | 2008 | Ecotoxicology and Environmental Safety2008，69，3： | 1 |
| 17 | The concept of the life cycle:an application to the tourist product显示文摘 | Da Conceiqao Gonqalves V F Roque Aguas P M | 1997 | Journal of Travel Research1997，36，2： | 1 |
| 18 | Pseudotumoral encapsulated fat necrosis with diffuse pseudomembranous degeneration显示文摘 | Felipo F Vaquero M del Agua C | 2004 | J Cutan Pathol2004，31，8： | 1 |
| 19 | Phenotypic concordance in familial inflammatory bowel disease (IBD). Results of a nationwide IBD Spanish database显示文摘 | Eduard Cabré Míriam Ma?osa Valle García-Sánchez Ana Gutiérrez Elena Ricart Maria Esteve Jordi Guardiola Mariam Aguas Olga Merino Angel Ponferrada Javier P. Gisbert Esther Garcia-Planella Gloria Ce?a José L. Cabriada Miguel Montoro Eugeni Domènech | 2013 | Journal of Crohn’s and Colitis2013，，： | 1 |
| 20 | Metal-ferroelectric thin film devices显示文摘 | KHOLKIN A L MARTINS R AGUAS H | 2002 | J Non-Cryst Solids2002，299，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员