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276篇 您的检索式：作者名="Aida Y"

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	题名	作者	年代	出处	被引量
1	脑缺血后N-myc下游调控基因2保护血脑屏障完整性显示文摘脑缺血后血脑屏障(BBB)的破坏与外周细胞向脑内浸润、病孔损形成与进展、以及临床病程恶化密切相关。目前BBB完整性的调控机制,尤其是在永久性缺血后的调控机制尚未明确。本研究使用小鼠永久性脑缺血模型进行相关研究,结果显示,星形胶质细胞N-myc下游调控基因2(NDRG2)可能是缺血性脑卒中后BBB通透性的调控分子,该分子与分化和应激相关。免疫组化显示,在永久性大脑中动脉闭塞(MCAO)后,NDRG2在星形胶质细胞中的表达显著增加。敲除NDRG2基因,脑梗死体积增加,免疫细胞在缺血同侧大脑半球积聚增加。MCAO后,NDRG2基因敲除小鼠缺血侧皮质的缺血灶内及灶周血管周围区域内的血清蛋白(包括纤维蛋白原和免疫球蛋白)的外渗增强此之,MCAO后NDRG2基因敲除小鼠体内基质金属蛋白酶(MMPs)的表达也显著增加。在细胞培养中,NDRG2-/-星形胶质细胞中MMP-3的表达和分泌增加,这种增加可被腺病毒介导的NDRG2再表达所逆转。综上所述,脑缺血后,星形胶质细胞内的NDRG2可能通过调节MMP的表达,而在BBB通透性的调节和免疫细胞浸润中起到重要作用。	Takarada-Iemata M Yoshikawa A Ta HM Okitani N Nishiuchi T Aida Y Kamide T Hattori T Ishii H Tamatani T Le TM Roboon J Kitao Y Matsuyama T Nakada M Hori O 聂昊	2018	神经损伤与功能重建2018，13，4：	4
2	Serum apolipoprotein B-100concentration predicts the virological response to pegylated interferon plus ribavirin combination therapy in patients infected with chronic hepatitis C virus genotype lb显示文摘	Yoshizawa K Abe H Aida Y	2013	J Med Virol2013，85，7：	1
3	Examination of Hrowizt,Howritz,and Cope's Construct of foreign language anxiety:The case of students of Japanese显示文摘	Aida Y		0，，02：	1
4	Examination of Horwitz and Cope' s Construct of Foreign Language Anxiety:The Case of Students of Japanese显示文摘	Aida Y	1994	Modem Language Journal1994，78，2：	1
5	Analysis of raw meats and fats of pigs using polymerase chain reaction for Halal authentication 显示文摘	Aida A A Che Man Y B Wong C M V L	2005	Meat Science2005，69，：	1
6	Serum immunoreactive collagen IV detected by monoclonal antibodies as a marker of severe fibrosis in patients with non-alcoholic fatty liver disease显示文摘	Aida Y Abe H Tomita Y	2015	J Gastrointestin Liver Dis2015，24，1：	1
7	Enterovims infection, CXC chemokine ligand 10 ( CXCLi0 ), and CXCR3 circuit: a mechanism of accelerated beta - cell failure in fulminant type 1 diabetes 显示文摘	TANAKA S NISHIDA Y AIDA K	2009	Diabetes2009，58，：	1
8	The relationship between serum uric acid and spirometic values in participants in a health check:the Takahata study 显示文摘	Aida Y Shibata Y Osaka D		Int J Med Sci 201 I 8(6')0，，：	1
9	Examinadon of Horwitz,Horwitz and Cope's construct of foreign language anxiety:The case of students of Japanese显示文摘	Aida Y	1994	Modem Lan-guage Journal1994，78，：	1
10	Microscopic intraosseous extension of ostensarcoma:assessment on dynamic enhanced MRI显示文摘	Iwasawa T Tanaka Y Aida N	1997	Skeletal Radiol1997，26，4：	1
11	Dehydration of d-glucose in high temperature water at pressures up to 80 MPa显示文摘	Aida T M Sato Y Watanabe M	2007	The Journal of Supercritical Flu- ids2007，40，3：	1
12	Anesthetic management with sevoflurane for internal fixation of long bone fracture in a horse 显示文摘	Ohashi N Aida H	1996	J Equine Sci1996，7，：	1
13	Production of γ-polyglutamic acid by Bacillus licheniformis A35 under denitrifying conditions显示文摘	Cheng C Asada Y Aida T	1989	Agricultural and Biological Chemistry1989，53，9：	1
14	Examination of Horwitz, Horwitz and Cope's construct of foreign language anxiety: the case of students of Japanese显示文摘	Y	1994	The Modern Language Journal1994，，78：	1
15	Identification of bovine invariant chain (Ii) gene by nucleotide sequencing 显示文摘	Niimi M Nakai Y Aida Y	1996	Biochem Biophys Res Commun1996，222，1：	1
16	The relationship between serum uric acid and spirometric values in participants in a health check:the Takahata study显示文摘	Aida Y Shibata Y Osaka D	2011	Int J Med Sci2011，8，6：	1
17	Dehydration of D - glucose in high temperature water at pressures up to 80 MPa显示文摘	Aida TM Sato Y Watanabe M Tarima K Nonaka T Hattori H	2007	Supercrit Fluids2007，40，3：	1
18	Dehydration of D-glucose in high temperature water at pressures up to 80 MPa显示文摘	Aida T M Sato Y Watanabe M	2007	Supercrit Fluids2007，40，3：	1
19	Phenitye and ontogeny of ce lls carrying atumor-associated antigen that is expressed on bovine leukemia virus-inducedlyphosarcoma显示文摘	Aida Y,Okawa K Amanuma H	1993	Cancer Res,1993，，：	1
20	Examination of Horowitz, Horowitz, and Cope Construct of Foreign Language Anxiety: The Case of Students of Japanese 显示文摘	Aida Y	1994	Modem Language Journal1994，78，2：	1

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