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| 1 | Intussusception in adults:Clinical characteristics,diagnosis and operative strategies显示文摘AIM:To evaluate 20 adults with intussusception and to clarify the cause, clinical features, diagnosis, and management of this uncommon entity.METHODS: A retrospective review of patients aged >18 years with a diagnosis of intestinal intussusception between 2000 and 2008. Patients with rectal prolapse, prolapse of or around an ostomy and gastroenterostomy intussusception were excluded. RESULTS: There were 20 cases of adult intussusception. Mean age was 47.7 years. Abdominal pain, nausea, and vomiting were the most common symptoms. The majority of intussusceptions were in the small intestine (85%). There were three (15%) cases of colonic intussusception. Enteric intussusception consisted of five jejunojejunal cases, nine ileoileal, and four cases of ileocecal invagination. Among enteric intussusceptions, 14 were secondary to a benign process, and in one of these, the malignant cause was secondary to metastatic lung adenocarcinoma. All colonic lesions were malignant. All cases were treated surgically. CONCLUSION: Adult intussusception is an unusual and challenging condition and is a preoperative diagnostic problem. Treatment usually requires resection of the involved bowel segment. Reduction can be attempted in small-bowel intussusception if the segment involved is viable or malignancy is not suspected; however, a more careful approach is recommended in colonic intussusception because of a significantly higher coexistence of malignancy. | Savas Yakan Cemil Caliskan Ozer Makay Ali Galip Denecli Mustafa Ali Korkut | 2009 | World Journal of Gastroenterology2009，15，16： | 12 |
| 2 | Gallbladder polyps: Factors affecting surgical decision显示文摘AIM: To determine the factors affecting the decision to perform surgery, and the efficiency of ultrasonography (USG) in detecting gallbladder polyps (GP). METHODS: Data for 138 patients who underwent cholecystectomy between 1996 and 2012 in our clinic with a diagnosis of GP were retrospectively analyzed. Demographic data, clinical presentation, principal symptoms, ultrasonographic and histopathological findings were evaluated. Patients were evaluated in individual groups according to the age of the patients (older or younger than 50 years old) and polyp size (bigger or smaller than 10 mm) and characteristics of the polyps (pseudopolyp or real polyps). χ 2 tests were used for the statistical evaluation of the data. RESULTS: The median age was 50 (26-85) years and 91 of patients were female. Of 138 patients who underwent cholecystectomy with GP diagnosis, only 99 had a histopathologically defined polyp; 77 of them had pseudopolyps and 22 had true polyps. Twenty-one patients had adenocarcinoma. Of these 21 patients, 11 were male, their median age was 61 (40-85) years and all malignant polyps had diameters > 10 mm (P< 0.0001). Of 138 patients in whom surgery were performed, 112 had ultrasonographic polyps with diameters < 10 mm. Of the other 26 patients who also had polyps with diameters > 10 mm, 22 had true polyps. The sensitivity of USG was 84.6% for polyps with diameters > 10 mm (P < 0.0001); however it was only 66% in polyps with diameters < 10 mm. CONCLUSION: The risk of malignancy was high in the patients over 50 years old who had single polyps with diameters > 10 mm. | Pinar Sarkut Sadik Kilicturgay Ali Ozer Ersin Ozturk Tuncay Yilmazlar | 2013 | World Journal of Gastroenterology2013，19，28： | 12 |
| 3 | Factors affecting anxiety, depression, and self-care ability in patients who have undergone liver transplantation显示文摘BACKGROUND Depression,anxiety,and altered self-care ability are among the most important factors affecting the quality of life of liver transplant recipients.Depending on the severity of the underlying liver disease,signs and symptoms of anxiety and depression may become more pronounced.AIM To evaluate the factors affecting depression,anxiety and self-care abilities of liver transplant recipients.METHODS Recipients who are≥18 years and who underwent liver transplantation at Inonu University Liver Transplantation Institute were included in this descriptive and cross-sectional study.Sample size analysis showed that the minimum number of recipients should be 301(confidence level=95%,confidence interval=2.5,population=1382).Three hundred and twenty recipients were interviewed and 316 recipients that have answered the questionnaires accurately were analyzed.The dependent variables were the Beck Depression Scale,State-Trait Anxiety Scale(Form I and II),and Self-Care Agency Scale.The independent variables of the study were sociodemographic characteristics,biliary complications,hepatocellular carcinoma,recommending liver transplantation to other patients,and the interval of out-patient clinic visits.RESULTS Self-care ability scores were lower(P=0.002)and anxiety scores were higher(P=0.004)in recipients with biliary complications.On the other hand,in recipients with hepatocellular carcinoma,self-care scores were lower(P=0.006)while depression(P=0.003)and anxiety scores(P=0.009)were higher.Liver transplantation recipients with a monthly income<3000 Turkish liras had higher depression(P<0.001)and anxiety(P=0.003)scores.The recipients who stated that they would not recommend liver transplantation to others had lower self-care scores(P=0.002),higher depression(P<0.001),higher state anxiety(P=0.02),and trait anxiety(P<0.001)scores.CONCLUSION Presence of biliary complications and hepatocellular carcinoma,low income level,and an obligation for monthly visits to the outpatient clinic are factors that are found to affect self-care capability,depression,and anxiety. | Sami Akbulut Ali Ozer Hasan Saritas Sezai Yilmaz | 2021 | World Journal of Gastroenterology2021，27，40： | 2 |
| 4 | Attitudes,awareness,and knowledge levels of the Turkish adult population toward organ donation:Study of a nationwide survey显示文摘BACKGROUND The most important factors affecting attitudes on organ donation are socioeconomic, educational, cultural, and religious factors in many countries.AIM To evaluate the attitudes, awareness, and knowledge levels of the Turkish adult population toward organ donation.METHODS This nationwide study surveyed 3000 adults(≥ 18 years) in Turkey. To ensure a representative sample, the Nomenclature of Territorial Units for Statistics-Ⅱ(modified for Turkey) was used. Turkey was divided into 26 regions based on social, economic, and geographic criteria as identified by the Turkish Statistical Institute. A stratified sampling method was used with an even distribution of adults across cities and towns based on population data. Data were collected by the PRP Research and Consultancy Company using computer-assisted personal interviews.RESULTS Out of 3000 individuals represented in the study population, 1465(48.8%) were male and 1535(51.2%) female. The results showed that most participants were under 45 years(59.0%) and married(72.1%), some had a bachelor’s degree or higher(21.9%), and very few(1.5%) had any direct experience with organ transplantation-whether in the family, or a family member on a transplantation waiting list. Most of the study population(88.3%) had not considered donating an organ, however, most(87.9%) said that they would accept an organ from a donor if they needed one. Among the individuals surveyed, 67% were willing to donate an organ to a close relative, while 26.8% would donate an organ to an unrelated person. Only 47.2% said they had adequate information about brain death, and 85.2% refused to consent to donating organs of family members declared brain dead. Only 33.9% thought they had adequate information about organ donation. The main source of information was the television. The two main reasons for refusing organ donation were that it was too soon to think about organ donation and the importance of retaining the integrity of the dead person’s body.CONCLUSION This study showed that Turkey’s adult population has inadequate knowledge about organ donation. The study advocates for public education programs to increase awareness among the general population about legislation related to organ donation. | Sami Akbulut Ali Ozer Ayse Gokce Khaled Demyati Hasan Saritas Sezai Yilmaz | 2020 | World Journal of Clinical Cases2020，8，11： | 2 |
| 5 | Gastric Necrosis due to Acute Massive Gastric Dilatation显示文摘 | Ibrahim Aydin Ahmet Pergel Ahmet Fikret Yucel Dursun Ali Sahin Ender Ozer Yasuhiko Sugawara | 2013 | <journal-title>Case Reports in Medicine2013，，： | 1 |
| 6 | High Power Diode Laser Vaporization of the Prostate: Preliminary Results for Benign Prostatic Hyperplasia显示文摘 | Ali Erol Kamil Cam Ali Tekin Omur Memik Soner Coban Yavuz Ozer | 2009 | The Journal of Urology2009，，： | 1 |
| 7 | Effects of N-acetylcysteine on regeneration following partial hepatectomy in rats with nonalcoholic fatty liver disease显示文摘 | Mehmet Ali Uzun Neset Koksal Huseyin Kadioglu Yusuf Gunerhan Suat Aktas Nevra Dursun Ahmet Ozer Sehirli | 2009 | Surgery Today2009，，7： | 1 |
| 8 | Jejunoduodenal intussus-ception caused by a solitary polyp in a woman with Peutz - Jegherssyndrome;a case report显示文摘 | Ali Ozer Pinar Sarkut Ersin Ozturk | 2014 | J Med Case Rep2014，8，： | 1 |
| 9 | Bi- lateral Late Remote Cerebellar Hemorrhage as a Complication of a Lumbo-Peritoneal Shunt Applied After Spinal Arteriovenous Malformation Surgery 显示文摘 | Mehdi Sasani Hadi Sasani Ali F Ozer | 2010 | The Journal of Spinal Cord Medicine2010，33，1： | 1 |
| 10 | Virulence Factors and Antibiotic Resistance in Children With Helicobacter pylori Gastritis显示文摘 | Hamza Karabiber Mukadder A. Selimoglu Baris Otlu Ozge Yildirim Ali Ozer | 2014 | Journal of Pediatric Gastroenterology and Nutrition2014，，5： | 1 |
| 11 | Plasma selenium,zinc,copper and lipid levels in postmenopausal turkish women and theirrelation with osteoporosis显示文摘 | Deniz Cemgil Arikan Ayhan Coskun Ali Ozer | 2011 | Biol Trace Elem Res2011，144，： | 1 |
| 12 | Blood pressure changes in young male subjects exposed to a median altitude显示文摘 | Ali Sizlan Recai Ogur Mustafa Ozer M. Kemal Irmak | 2008 | Clinical Autonomic Research2008，，2： | 1 |
| 13 | Electrolyzed oxidizing water treatment for decontamination of raw salmon inoculated with Escherichia coli O157:H7 and Listeria monocytogenes Scott A and response surface modeling显示文摘 | Nil P. Ozer Ali Demirci | 2005 | Journal of Food Engineering2005，，3： | 1 |
| 14 | 便携式肠道超声检查对克罗恩病治疗的影响显示文摘背景:肠道超声(IUS)是评估克罗恩病的一种有效的横断面影像技术。随着技术进步,便携式超声系统的应用越来越广泛,非影像专业的临床医生使用该设备有望大大提高患者的诊治效能。本研究旨在评估胃肠科医生使用便携式超声系统进行IUS检查,作为克罗恩病患者辅助影像学检查的诊断价值。方法:117例克罗恩病患者接受了IUS检查。记录检查前后的治疗决策。主要结局指标是评估IUS检查后治疗决策的改变。以基于患者所有相关资料评估后的多学科团队讨论所制定的治疗决策作为金标准,评估基于胃肠科医生进行IUS检查后所作出治疗决策的准确性。采用克罗恩病简单内镜评分(SES-CD)评估内镜下疾病活动度。结果:IUS检查后,47例(40.2%)患者最初的治疗决策发生了改变(P=0.001)。治疗决策的准确率由63.2%提高到90.6%(P<0.001)。IUS检查后,13例患者被评估为需要急诊外科/介入干预。肠镜(SES-CD≥3)与IUS异常发现用于治疗决策的准确率分别为94%和91%,灵敏度分别为95%和94%。结论:使用便携式超声系统进行IUS检查可显著提高临床决策的准确性。若获得进一步的数据支持,该检查模式可能会成为CD治疗决策的必需。 | Can Gonen Ali Surmelioglu Koray Kochan Serhat Ozer Ekrem Aslan Metin Tilki | 2021 | Gastroenterology Report2021，9，5： | 0 |
| 15 | Attitudes, knowledge levels and behaviors of Islamic religious officials about organ donation in Turkey: National survey study显示文摘BACKGROUND The most important factors affecting the decision of organ donation are socioeconomic,educational,cultural,and religious factors.AIM To evaluate Islamic religious officials’attitudes and behaviors toward and level of knowledge on organ donation and transplantation.METHODS This study surveyed 2350 Islamic religious officials in Turkey.To ensure a representative sample,we used and modified the Nomenclature of Territorial Units for Statistics.Based on the Nomenclature of Territorial Units for Statistics-II,Turkey was divided into 26 regions.The number of Islamic religious officials in each city and town in each of the 26 regions was proportionate to the population.A stratified sampling method based on demographic factors,such as age,marital status,and educational level,was used.Data were collected by PRP Research and Consultancy Company using computer-assisted personal interviewing.RESULTS Of the 2350 religious officials surveyed,59.9%were in the age group of 35-54 years;84.7%had either a bachelor’s or a master’s degree;99.7%never donated an organ;and 75.4%were not considering donating in the future.About 22%of the religious officials said religious belief was their reason for not donating;45.3%did not indicate any reason.Although 41.5%of participants considered cadaveric organ donation as the best source of organ transplantation,36.3%deemed living donor transplantation as the best option.Meanwhile,52.9%of participants considered donating an organ from a brain dead relative in case they were asked for permission;80.1%considered donating to a relative,if necessary;81.6%considered undergoing organ transplantation,if necessary.About 83.7%of participants deemed organ donation as a proper human behavior;60.5%believed that it is allowed by Islam;55%said they preach for organ donation at their mosque;and 41.1%said their views of organ donation were influenced by their leaders in society.CONCLUSION Religious officials are unsure whether or not organ donation is respectful of their religious belief,but they consider donating an organ if a relative need to undergo organ transplantation. | Sami Akbulut Ali Ozer Betul Firinci Hasan Saritas Khaled Demyati Sezai Yilmaz | 2020 | World Journal of Clinical Cases2020，8，9： | 0 |
| 16 | Effect of the COVID-19 pandemic on patients with presumed diagnosis of acute appendicitis显示文摘BACKGROUND Acute appendicitis(AAp) is the most frequent cause of acute abdominal pain,and appendectomy is the most frequent emergency procedure that is performed worldwide.The coronavirus disease 2019(COVID-19) pandemic has caused delays in managing diseases requiring emergency approaches such as AAp and trauma.AIM To compare the demographic,clinical,and histopathological outcomes of patients with AAp who underwent appendectomy during pre-COVID-19 and COVID-19 periods.METHODS The demographic,clinical,biochemical,and histopathological parameters were evaluated and compared in patients who underwent appendectomy with the presumed diagnosis of AAp in the pre-COVID-19(October 2018-March 2020) and COVID-19(March 2020-July 2021) periods.RESULTS Admissions to our tertiary care hospital for AAp increased 44.8% in the COVID-19 period.PreCOVID-19(n = 154) and COVID-19(n = 223) periods were compared for various parameters,and we found that there were statistically significant differences in terms of variables such as procedures performed on the weekdays or weekends [odds ratio(OR):1.76;P = 0.018],presence of AAp findings on ultrasonography(OR:15.4;P < 0.001),confirmation of AAp in the histopathologic analysis(OR:2.6;P = 0.003),determination of perforation in the appendectomy specimen(OR:2.2;P = 0.004),the diameter of the appendix(P < 0.001),and hospital stay(P = 0.003).There was no statistically significant difference in terms of interval between the initiation of symptoms and admission to the hospital between the pre-COVID-19(median:24 h;interquartile range:34) and COVID-19(median:36 h;interquartile range:60) periods(P = 0.348).The interval between the initiation of symptoms until the hospital admission was significantly longer in patients with perforated AAp regardless of the COVID-19 or pre-COVID-19 status(P < 0.001).CONCLUSION The present study showed that in the COVID-19 period,the ultrasonographic determination rate of AAp,perforation rate of AAp,and duration of hospital stay increased.On the other hand,negative appendectomy rate decreased.There was no statistically significant delay in hospital admissions that would delay the diagnosis of AAp in the COVID-19 period. | Sami Akbulut Adem Tuncer Zeki Ogut Tevfik Tolga Sahin Cemalettin Koc Emek Guldogan Ertugrul Karabulut Elif Seren Tanriverdi Ali Ozer | 2022 | World Journal of Clinical Cases2022，10，29： | 0 |
| 17 | Development of a functional chocolate using gamma-amino butyric acid producer Lacticaseibacillus rhamnosus NRRL B-442显示文摘The human microbiota is influenced by the immune and nervous systems of the host.Gamma-aminobutyric acid (GABA) is known as bioactive compound and it has important physiological functions,such as anti-hypertensive and antidepressant activities.Lactic acid bacteria (LAB),especially Lactobacillus species are known as the most important GABA producers because of the food-grade nature.The purpose of this study is to develop a functional chocolate using microencapsulated GABA producer Lacticaseibacillus rhamnosus NRRL B-442 strain for patients having an anxiety disorder.Water-in-oil emulsion technique was conducted for microencapsulation using whey-pullulan complex.Microencapsulated and free L.rhamnosus cell counts were 6.75 and 7.20 log CFU/g in chocolates,respectively,at the end of 60 days.During simulated in vitro digestion analysis,survival rate of microencapsulated bacteria in chocolate samples was found at higher percentage (87%) than free bacteria (75%).Furthermore,microencapsulated L.rhamnosus did not affect the physical,chemical,and sensory properties of chocolate.Consequently,L.rhamnosus with the highest GABA producing capability may provide insight for an anxiety disorder patient,since this strain has been thought as having a therapeutic effect.A new functional food model was developed for “GutBrain Axis” phenomena since the chocolate could be accepted as a good carrier for GABA producer bacteria. | Merve Ozer Burcu Ozturk Ali Adnan Hayaloglu Sebnem Tellioglu Harsa | 2022 | Food Bioscience2022，47，3： | 0 |
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