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| 1 | Transcranial Doppler ultrasonography: From methodology to major clinical applications显示文摘Non-invasive Doppler ultrasonographic study of cerebral arteries [transcranial Doppler(TCD)] has been extensively applied on both outpatient and inpatient settings. It is performed placing a low-frequency(≤ 2 MHz) transducer on the scalp of the patient over specific acoustic windows, in order to visualize the intracranial arterial vessels and to evaluate the cerebral blood flow velocity and its alteration in many different conditions. Nowadays the most widespread indication for TCD in outpatient setting is the research of right to left shunting, responsable of so called 'paradoxical embolism', most often due to patency of foramen ovale which is responsable of the majority of cryptogenic strokes occuring in patients younger than 55 years old. TCD also allows to classify the grade of severity of such shunts using the so called 'microembolic signal grading score'. In addition TCD has found many useful applications in neurocritical care practice. It is useful on both adults and children for day-to-day bedside assessment of critical conditions including vasospasm in subarachnoidal haemorrhage(caused by aneurysm rupture or traumatic injury), traumatic brain injury, brain stem death. It is used also to evaluate cerebral hemodynamic changes after stroke. It also allows to investigate cerebral pressure autoregulation and for the clinical evaluation of cerebral autoregulatory reserve. | Antonello D'Andrea Marianna Conte Massimo Cavallaro Raffaella Scarafile Lucia Riegler Rosangela Cocchia Enrica Pezzullo Andreina Carbone Francesco Natale Giuseppe Santoro Pio Caso Maria Giovanna Russo Eduardo Bossone Raffaele Calabrò | 2016 | World Journal of Cardiology2016，8，7： | 10 |
| 2 | Stem cell treatment and cerebral palsy: Systemic review and meta-analysis显示文摘BACKGROUND Perinatal complications may result in life-long morbidities,among which cerebral palsy(CP)is the most severe motor disability.Once developed,CP is a nonprogressive disease with a prevalence of 1-2 per 1000 live births in developed countries.It demands an extensive and multidisciplinary care.Therefore,it is a challenge for our health system and a burden for patients and their families.Recently,stem cell therapy emerged as a promising treatment option and raised hope in patients and their families.AIM The aim is to evaluate the efficacy and safety of stem cell treatment in children with CP using a systematic review and meta-analysis METHODS We performed a systematic literature search on PubMed and EMBASE to find randomized controlled clinical trials(RCT)investigating the effect of stem cell transplantation in children with CP.After the review,we performed a randomeffects meta-analysis focusing on the change in gross motor function,which was quantified using the gross motor function measure.We calculated the pooled standardized mean differences of the 6-and/or 12-mo-outcome by the method of Cohen.We quantified the heterogeneity using the I-squared measure.RESULTS We identified a total of 8 RCT for a qualitative review.From the initially selected trials,5 met the criteria and were included in the meta-analysis.Patients’population ranged from 0.5 up to 35 years(n=282).We detected a significant improvement in the gross motor function with a pooled standard mean difference of 0.95(95%confidence interval:0.13-1.76)favoring the stem cell group and a high heterogeneity(I2=90.1%).Serious adverse events were rare and equally distributed among both intervention and control groups.CONCLUSION Stem cell therapy for CP compared with symptomatic standard care only,shows a significant positive effect on the gross motor function,although the magnitude of the improvement is limited.Short-term safety is present and further highquality RCTs are needed. | Simone Eggenberger Céline Boucard Andreina Schoeberlein Raphael Guzman Andreas Limacher Daniel Surbek Martin Mueller | 2019 | World Journal of Stem Cells2019，11，10： | 8 |
| 3 | ROS-induced DNA damage and PARP-1 are required for optimal induction of starvation-induced autophagy显示文摘响应滋养的应力,房间开始能导致改编或死亡的一个 autophagy 节目。位于从饥饿发信号到 autophagy 的开始下面的机制充分没被理解。在当前的学习,我们证明 PARP-1 的缺席或 inactivation 强烈推迟导致饥饿的 autophagy。我们发现了那 DNA 损坏是由 γ 测量了的导致饥饿的 autophagy 的一个早事件; -H2AX 累积和彗星试金,与在两个参数显示减小的 PARP-1 猛烈房间。在饥饿期间,导致 ROS 的 DNA 损坏激活 PARP-1,导致 ATP 弄空(在滋养的剥夺以后的一个早事件) 。PARP-1 的缺席弄钝 AMPK 激活并且阻止了 mTOR 活动的完全的损失,导致在 autophagy 的延期。PARP-1 弄空在饥饿的房间赞成 apoptosis,建议在滋养的剥夺以后的 autophagy 和 PARP-1 激活的一个支持幸存的角色。在 PARP-1 变异的老鼠的出生不满一月的婴儿使遭到了到尖锐饥饿的 vivo 结果表演,也显示缺乏的肝 autophagy,暗示为在导致饥饿的 autophagy 的 PARP-1 的一个生理的角色。因此,表明小径的 PARP 是 autophagy 承诺追随者饥饿的起始的步骤的一个关键管理者。 | Jose Manuel Rodriguez-Vargas Maria Jose Ruiz-Magana Carmen Ruiz-Ruiz Jara Majuelos-Melguizo Andreina Peralta-Lea Maria Isabel Rodriguez Jose Antonio Munoz-Gaimez Mariano Ruiz de Almodovar Eva Siles Abelardo Lopez Rivas Marja Jaattela F Javier Oliver | 2012 | Cell Research2012，22，7： | 8 |
| 4 | Cardiac damage in athlete's heart: When the “supernormal” heart fails!显示文摘Intense exercise may cause heart remodeling to compensate increases in blood pressure or volume by increasing muscle mass. Cardiac changes do not involve only the left ventricle, but all heart chambers. Physiological cardiac modeling in athletes is associated with normal or enhanced cardiac function, but recent studies have documented decrements in left ventricular function during intense exercise and the release of cardiac markers of necrosis in athlete's blood of uncertain significance. Furthermore, cardiac remodeling may predispose athletes to heart disease and result in electrical remodeling, responsible for arrhythmias. Athlete's heart is a physiological condition and does not require a specific treatment. In some conditions, it is important to differentiate the physiological adaptations from pathological conditions, such as hypertrophic cardiomyopathy, arrhythmogenic dysplasia of the right ventricle, and non-compaction myocardium, for the greater risk of sudden cardiac death of these conditions. Moreover, some drugs and performance-enhancing drugs can cause structural alterations and arrhythmias, therefore, their use should be excluded. | Andreina Carbone Antonello D’Andrea Lucia Riegler Raffaella Scarafile Enrica Pezzullo Francesca Martone Raffaella America Biagio Liccardo Maurizio Galderisi Eduardo Bossone Raffaele Calabrò | 2017 | World Journal of Cardiology2017，9，6： | 3 |
| 5 | Analysis of braincomplexity and mental disorders显示文摘 | Fem6ndez A Andreina MM Homero R | 2010 | Actas Esp Psiquiatr2010，38，4： | 1 |
| 6 | Adria mycin--induced nephrotic syndrome 显示文摘 | Bertaim T Andreina P Bid D | 1982 | Lab Invest1982，46，： | 1 |
| 7 | Massive left atrial calcification, tracheobronchopathia osteoplastica and mitral paravalvular leak associated with cardiac rheumatic disease and previous mitral valve replacement显示文摘 | Alejandro Vidal Natalia Lluberas Lucía Florio Andreina Gómez Diego Russo Valentina Agorrody Sebastián Albistur Ricardo Lluberas | 2013 | International Journal of Cardiology2013，，： | 1 |
| 8 | Soil and compost humic fractions regulate the response of Sclerotinia sclerotiorum to exogenously added allelochemical compounds显示文摘 | Elisabetta Loffredo Andreina Traversa | 2014 | Biology and Fertility of Soils2014，，： | 1 |
| 9 | Phase Transfer Nu- cleophilic Aromatic Substitution of Chromium Tricarbonyl Complexed Dichloro Benzenes with Alcohols显示文摘 | Andreina A Clara B Paola D B | 1985 | Gazz Chim Ital1985，115，10： | 1 |
| 10 | Retrospective study of a large population of patients with asymptomatic or minimally symptomatic raised serum creatine kinase levels显示文摘 | Alessandro Prelle Lucia Tancredi Monica Sciacco Luca Chiveri Giacomo P. Comi Alessandro Battistel Paola Bazzi Filippo Martinelli Boneschi Vincenzo Bagnardi Patrizia Ciscato Andreina Bordoni Franco Fortunato Sandra Strazzer Nereo Bresolin Guglielmo Scarlat | 2002 | Journal of Neurology2002，，3： | 1 |
| 11 | 脂肪移植的研究:第二部分 注射设备对脂肪物质属性的影响显示文摘目的尽管脂肪移植可以治疗多种软组织缺陷,但其结果仍有一定的不确定性。本研究中,我们将对使用一种自动、低剪切力装置或改良Coleman技术注射脂肪的物理性质进行对比。方法从9例患者处提取脂肪抽吸物,经过处理后采取改良Coleman技术或一种自动、低剪切力装置进行脂肪注射。通过一种2mm口径套管注入脂肪,并与微处理的脂肪进行对比。当组织开始失去其固态性质时,利用血流速度计测量其存储模量及剪切速率。同时,对脂肪组织的黏性进行测量,并通过载玻片实验定性评估每个治疗组的总产量。结果利用自动、低剪切力装置注射的脂肪,其物理性质与微处理的脂肪最接近。该自动装置组的脂肪存储模量(G’)比改良Coleman技术组高,而强度极限更延后。同样,测得该自动装置组的脂肪黏性与微处理组相当,比改良Coleman技术组的高。结论与改良Coleman技术相比,利用连于2mm插管的自动、低剪切力装置处理的脂肪抽吸物可以更好地保留脂肪组织完整的物理性质。本研究通过流变数据证实,该自动装置比改良Coleman技术对脂肪组织的损伤更小,其应用可能会增加移植脂肪的完整性。 | David Atashroo Jordan Raphel Michael T. Chung Kevin J. Paik Andreina Parisi-Amon Adrian McArdle Kshemendra Senarath-Yapa Elizabeth R. Zielins Ruth Tevlin Chris Duldulao Graham G. Walmsley Michael S. Hu Arash Momeni Brian Domecus Joe R. Rimsa Lauren Greenberg Geoffrey C. Gurtner Michael T. Longaker Derrick C. Wan 魏峰 高景恒 张晨 | 2014 | 中国美容整形外科杂志2014，25，10： | 1 |
| 12 | Chemical and spectroscopic characteristics of humic acids and dissolved organic matter along two Alfisol profiles显示文摘 | Andreina Traversa Valeria D Orazio Giuseppe Natale Mezzape- sa | 2014 | Chemosphere2014，，111： | 1 |
| 13 | Adriamycin induced nephrotic-syndrome in rat显示文摘 | Bertain T Andreina P BioIDetal | 1982 | Lab Invest1982，46，： | 1 |
| 14 | Flavonoids apigenin and quercetin inhibit melanoma growth and metastatic potential显示文摘 | SARA C COSMO R ANDREINA P etal | 2000 | Int J Cancer2000，87，3： | 1 |
| 15 | A Randomized Trial of Circumferential Pulmonary Vein Ablation Versus Antiarrhythmic Drug Therapy in Paroxysmal Atrial Fibrillation显示文摘 | Carlo Pappone Giuseppe Augello Simone Sala Filippo Gugliotta Gabriele Vicedomini Simone Gulletta Gabriele Paglino Patrizio Mazzone Nicoleta Sora Isabelle Greiss Andreina Santagostino Laura LiVolsi Nicola Pappone Andrea Radinovic Francesco Manguso Vincenzo | 2006 | Journal of the American College of Cardiology2006，，11： | 1 |
| 16 | Placental mesenchymal stem cells as potential autologous graft for pre- and perinatal neuroregeneration显示文摘 | C. Bettina Portmann-Lanz Andreina Schoeberlein Alexander Huber Ruth Sager Antoine Malek Wolfgang Holzgreve Daniel V. Surbek | 2006 | American Journal of Obstetrics and Gynecology2006，，3： | 1 |
| 17 | Tissue-specific engraftment after in utero transplantation of allogeneic mesenchymal stem cells into sheep fetuses 显示文摘 | Andreina S Wolfgang H Lisbeth D | 2005 | Am J Obstet Gynecol2005，192，3： | 1 |
| 18 | Bounded Sociability, Relationship Costs and Intangible Resources in Complex显示文摘 | Andreina Mandelli | 2002 | Digital Networks IT & Society Summer 20022002，1，1： | 1 |
| 19 | A new integrated silicon gate technology combining bipolar linear, CMOS logic, and DMOS power parts 显示文摘 | Andreina A Contiero C Galbiati P | 1986 | IEEE Transactions on Electron Devices1986，33，12： | 1 |
| 20 | Flavonoids apigenin and quercetin inhibitmelanoma growth and metastatic potential显示文摘 | SARA C COSMO R ANDREINA P | 2000 | Int J Cancer2000，87，3： | 1 |
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