| 3 | DNA damage in exfoliated buccal cells and antioxidant status of saliva in brain tumour patients显示文摘The present investigation was carried out in exfoliated buccal cells and saliva collected from pre-operative brain tumour patients. The DNA damage in these cells was assessed by alkaline comet assay and micronucleus (MN) assay. Salivary flow rate, pH, osmolality, total antioxidant activity (AOA) and vitamin C levels were also assessed in unstimulated whole saliva of these patients. In the comet assay a significant increase in the tail length (P<0.02) was observed when control and malignant groups were compared. A significant (P<0.02) difference in tail length was also noted between benign and malignant groups. Non significant results were found when control and benign groups were compared. Further, a marked increase in % MN (P<0.002) was observed when control and benign groups were compared. A significant increase in % MN (P<0.029) was also observed in benign cases when compared to malignant tumours. No significance was obtained when % MN in control and malignant cases was compared. Moreover, salivary flow rate and pH was significantly decreased and osmolality was markedly increased in brain tumour patients. The AOA levels in saliva were markedly decreased in brain tumours and vitamin C levels exhibited no change when compared to controls. Thus, as noted above susceptibility to free radical induced DNA damage also exists in the exfoliated buccal cells conducive to the lowered salivary antioxidant status of brain tumour patients. | Revathi P Shenoy Anumeha Vatsa Swagatika Sahoo Rajashree Rana Guruprasad Nayak Poorna Bhat Guruprasad Kalthur Anjali Rao | 2010 | 海南医学院学报2010,16,10: | 0 |
| 4 | Further contribution to the Neogene petrified wood forest of Mizoram, India显示文摘Mizoram, a state situated in the northeast corner of India, is very rich in fossil woods belonging to the Tipam Group(Late Miocene-Early Pliocene in age). Four new fossil woods, namely Swintonioxylon hailakandiense Prakash & Tripathi, Bombacacioxylon tertiarum Mehrotra et al., gen. et sp. nov., Dipterocarpoxylon jammuense Guleria et al. and Bischofia palaeojavanica Awasthi are described from there. They resemble the modern taxa, namely Swintonia Griff.(Anacardiaceae), Dipterocarpus C.F. Gaertn.(Dipterocarpaceae), Bischofia Blume(Euphorbiaceae) and the taxa of the family Bombacaceae. The distribution of the modern equivalents of the present and previously described taxa indicates the existence of warm and humid climate in Mizoram during the depositional time. | MEHROTRA Rakesh Chandra TIWARI R P SRIVASTAVA Gaurav SHUKLA Anumeha | 2013 | 科学通报2013,58,S1: | 0 |
| 5 | Cenozoic flora of western India and its significance in palaeoclimatic and palaeophytogeographic interpretation显示文摘The Cenozoic flora of western India(Rajasthan and Gujarat) is adversely affected by the tectonic activity such as collision of the Indian subcontinent with the Eurasian plate which is responsible for the Himalayan and Tibetan Plateau uplift. This collision and its resultants affected the ubiquitous tropical lowland vegetation of the Indian subcontinent(including western India) and are responsible for different types of topographic regions as seen today in the Indian subcontinent. The region is important as it has witnessed a drastic change in climate of the region since the Cenozoic time and also provided opportunities to the western and eastern flora to intermingle. The main basins in western India comprising Cenozoic sequences are: Bikaner-Nagaur, Jaisalmer and Barmer in Rajasthan and Kachchh, Mainland and Saurashtra in Gujarat. These basins are very rich in lignite which is the main source of electric power generation in western India. This lignite is mainly of Eocene in age. The Cenozoic flora of western India was almost tropical growing in well drained areas as compared to arid to sub-humid regions with xeric vegetation today. The reported fossils are represented by leaves, woods, fruits and seeds. The leaves are abundant in the Palaeogene as compared to the Neogene. The Neogene period can be marked by the abundant legumes and dipterocarpaceous remains. The important families viz., Anacardiaceae, Annonaceae, Arecaceae, Calophyllaceae, Clusiaceae, Combretaceae, Euphorbiaceae, Flacourtiaceae, Icacinaceae, Lauraceae, Lythraceae, Meliaceae, Moraceae, Myrtaceae, Pandanaceae and Sonneratiaceae have been reported from the Palaeogene sediments, whereas Anacardiaceae, Araucariaceae, Arecaceae, Combretaceae, Dipterocarpaceae, Fabaceae, Lauraceae, Lecythidaceae, Lythraceae, Malvaceae, Meliaceae, Moraceae, Podocarpaceae, Rhamnaceae, Rhizophoraceae, Rutaceae, Sapindaceae and Sonneratiaceae are known from the Neogene sediments. All the recovered elements strongly indicate the presence of much better climatic conditions in the region during the Cenozoic as compared to the present. More importantly, a fossil fruit of Cocos L. described from the Eocene sediments of Rajasthan further indicates the presence of sea in the nearby area at the time of deposition of the sediments. The recovery of a few African elements from western India provides the evidence of establishment of land connections between India and Africa up to the Plio-Pleistocene through which these elements could enter the Indian subcontinent. | SHUKLA Anumeha MEHROTRA Rakesh Chandra | 2013 | 科学通报2013,58,S1: | 0 |