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| 1 | Fatty liver in hepatitis C patients post-sustained virological response with direct-acting antivirals显示文摘AIM To determine steatosis and fibrosis prevalence in hepatitis C patients after a sustained virological response achieved with direct-acting antivirals.METHODS Transient elastography with controlled attenuation parameter(CAP) was used to assess hepatic steatosis post-sustained virological response(SVR);the CAP technology was not available in the United States at study initiation.Liver stiffness/fibrosis was measured before and 47 wk after treatment completion.Patients with genotype 3 and patients with cirrhosis were excluded.RESULTS One hundred and one patients were included in the study.Post-SVR there were decreases from baseline in alanine aminotransferase(ALT)(63.1 to 17.8 U/L),aspartate aminotransferase(51.8 to 21.5 U/L) and fibrosis score(7.4 to 6.1 k Pa)(P < 0.05).Post-SVR,48 patients(47.5%) had steatosis on CAP;of these,6.25% had advanced fibrosis.Patients with steatosis had higher body mass index(29.0 vs 26.1 kg/m2),glucose(107.8 vs 96.6 mg/d L),ALT(20.4 vs 15.3 mg/d L),CAP score(296.3 vs 212.4 d B/m) and fibrosis score(7.0 vs 5.3 k Pa);P < 0.05.Interestingly,compared to baseline,both patients with and without steatosis had change in fibrosis score post-SVR(7.7 k Pa vs 7.0 k Pa and 7.0 k Pa vs 5.3 k Pa);alternatively,(P < 0.05) and therefore patients with steatosis continued to have clinically significant stiffness(≥ 7 k Pa).CONCLUSION Fatty liver is very common in hepatitis C virus(HCV) patients post-SVR.These patients continue to have elevated mean fibrosis score(≥ 7 k Pa) compared to those without fatty liver;some have advanced fibrosis.Long term follow up is needed to assess steatosis and fibrosis in HCV patients post-SVR. | Mazen Noureddin Micaela M Wong Tsuyoshi Todo Shelly C Lu Arun J Sanyal Edward A Mena | 2018 | World Journal of Gastroenterology2018，24，11： | 6 |
| 2 | A state-of-the-art review of solar passive building system for heating or cooling purpose显示文摘一座大楼里的精力的主要部分被加热消费,通气,并且空气调节(HVAC ) 。传统的加热并且冷却的系统极大地作出贡献到温室气体的排放,特别二氧化碳。四个不同方法,即, Trombe 墙,太阳的烟囱,无光的公开太阳的 fa ? 果汁饮料,和太阳的房顶,为太阳的加热被采用。同样,二主修方法,即,综合成为蒸气的冷却的成为蒸气的冷却并且造为大楼冷却被采用。因此,在这份报纸被尝试了编在一座大楼里的技术的太阳的加热并且冷却的开发。 | Arun Kumar NANDA C K PANIGRAHI | 2016 | Frontiers in Energy2016，10，3： | 3 |
| 3 | Carcinoma of the gallbladder显示文摘 | Sanjeev Misra Arun Chaturvedi Naresh C Misra Indra D Sharma | 2003 | Lancet Oncology2003，，3： | 2 |
| 4 | Pain management in mice using methanol extracts of three plants belongs to family Amaranthaceae显示文摘Objective:To investigate the analgesic activity of methanolic extract of Amaranthus viridis(A. viridis),Amaranthus caudatus(A.caudatus) and Amaranthus spinosus(A.spinosus).Methods:In this study,the analgesic activity of methanol extracts of all three plants at doses of 200 and 400 mg/kg were investigated by acetic acid-induced writhings test,hot plate test and tail immersion test for mice.Results:It was found that all the three plants showed significant pain management effect(P<0.01) at a dose of 400 mg/kg,but showed a less significant effect at a dose of 20 mg/kg in the entire tests used for evaluation of analgesic activities(P<0.05).Conclusions:Methanol extracts of A.viridis,A.caudatus and A.spinosus show potent analgesic activities,and this study provides the scientific proof for their traditional claims. | Ashok Kumar BS Lakshman K Jayaveera KN Vel Murgan C Arun Kumar PA Vinod Kumar R Meghda Hegade Sridhar SM | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，7： | 2 |
| 5 | Hydroxyurea treatment of sickle cell anemia in hospital - based practices 显示文摘 | Ferguson RP Arun A Carter C | 2002 | Am J Hematol2002，70，： | 1 |
| 6 | Extraction of peroxi- dase from waste Brassica aleraeea used for the treatment of aqueous phenol in synthetic waste water显示文摘 | Ashutash N D Arun C Arthanareeswaran g | 2014 | Journal of Environmental Chemical Engi ng2014，2，2： | 1 |
| 7 | Prognostic significance of elevated endothelin-1 levels in patients with colorectal cancer显示文摘 | Arun C London NJ Hemingway DM | 2004 | Int J Biol Markers2004，19，1： | 1 |
| 8 | Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity显示文摘 | Bhaskar G Arun Y Balachandran C | 2012 | Eur] Med Chern2012，51，1： | 1 |
| 9 | Endothelin-1 is a novel prognostic factor in non-small cell lung cancer显示文摘 | Arun C De Catris M Hemingway DM | 2004 | Int J Biol Markers2004，19，4： | 1 |
| 10 | Superhard nanocomposite coatings of TiN/Si3N4 prepared by reactive direct current unbalanced magnetron sputtering 显示文摘 | Harish C Barshilia Deepthi B Arun Prabhu A S | 2006 | Surface and Coatings Technology2006，201，12： | 1 |
| 11 | Defective N - acety- laspartate catabolism reduces brain acetate levels and myelin lipid synthesis in Canavan's disease 显示文摘 | Madhavarao C N Arun P Moffett J R | 2005 | Proc Natl Acad Sci U S A2005，102，14： | 1 |
| 12 | Study in sexuality of medical college students in India显示文摘 | Omprakash A Arun KS Pragti C | 2000 | Journal of Adolescent Health2000，26，： | 1 |
| 13 | Observational study of surface ozone at New Delhi ,India显示文摘 | JAIN S L ARYA B C ARUN K | 2005 | Interna- tional Journal of Remote Sensing2005，，： | 1 |
| 14 | Safe and shelf-stable natural casing using hurdle technology 显示文摘 | Chawla S P Ramesh C Arun S | 2006 | Food Control2006，17，2： | 1 |
| 15 | Carcinoma of the gallbladder显示文摘 | SANJEEV M ARUN C NARESH CM | 2003 | The Lancet Oncology2003，4，2： | 1 |
| 16 | Experimental is- in atmospheric boundary layer simulations: roughness length and integral length scale determina- tion显示文摘 | Arun K S Iyengar A K S Farell C | 2001 | Journal of Wind Engineering and Industrial Aerodynamics2001，89，： | 1 |
| 17 | Application of wastewater from paper and food seasoning industries with green manure to increase soil organic carbon: A laboratory study显示文摘 | Lin C C Arun A B Rekha P D | 2008 | Bioresour Technol2008，99，14： | 1 |
| 18 | Prognostic significance of elevated endothelin-1 levels in patients with colorectal cancer 显示文摘 | Arun C London N J Hemingway D M | 2004 | Int J Biol Markers2004，19，1： | 1 |
| 19 | Prognostic significance of elevated endothelin-1 levels in patients with eoloreetal cancer 显示文摘 | Arun C London N J Hemingway D M | 2004 | Int J Biol Markers2004，19，1： | 1 |
| 20 | Polymeric drug based on sulfanilamide: synthesis,antimicrobial and drug releasing studies显示文摘 | Umamaheswara Reddy C Arun A Amalraj A | 2007 | J Pharm Pharmacol2007，59，9： | 1 |
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