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| 1 | Fatty liver in hepatitis C patients post-sustained virological response with direct-acting antivirals显示文摘AIM To determine steatosis and fibrosis prevalence in hepatitis C patients after a sustained virological response achieved with direct-acting antivirals.METHODS Transient elastography with controlled attenuation parameter(CAP) was used to assess hepatic steatosis post-sustained virological response(SVR);the CAP technology was not available in the United States at study initiation.Liver stiffness/fibrosis was measured before and 47 wk after treatment completion.Patients with genotype 3 and patients with cirrhosis were excluded.RESULTS One hundred and one patients were included in the study.Post-SVR there were decreases from baseline in alanine aminotransferase(ALT)(63.1 to 17.8 U/L),aspartate aminotransferase(51.8 to 21.5 U/L) and fibrosis score(7.4 to 6.1 k Pa)(P < 0.05).Post-SVR,48 patients(47.5%) had steatosis on CAP;of these,6.25% had advanced fibrosis.Patients with steatosis had higher body mass index(29.0 vs 26.1 kg/m2),glucose(107.8 vs 96.6 mg/d L),ALT(20.4 vs 15.3 mg/d L),CAP score(296.3 vs 212.4 d B/m) and fibrosis score(7.0 vs 5.3 k Pa);P < 0.05.Interestingly,compared to baseline,both patients with and without steatosis had change in fibrosis score post-SVR(7.7 k Pa vs 7.0 k Pa and 7.0 k Pa vs 5.3 k Pa);alternatively,(P < 0.05) and therefore patients with steatosis continued to have clinically significant stiffness(≥ 7 k Pa).CONCLUSION Fatty liver is very common in hepatitis C virus(HCV) patients post-SVR.These patients continue to have elevated mean fibrosis score(≥ 7 k Pa) compared to those without fatty liver;some have advanced fibrosis.Long term follow up is needed to assess steatosis and fibrosis in HCV patients post-SVR. | Mazen Noureddin Micaela M Wong Tsuyoshi Todo Shelly C Lu Arun J Sanyal Edward A Mena | 2018 | World Journal of Gastroenterology2018,24,11: | 6 |
| 2 | Total hip arthroplasty in fused hips with spine stiffness in ankylosing spondylitis显示文摘Ankylosing spondylitis(AS)is characterized by involvement of the spine and hip joints with progressive stiffness and loss of function.Functional impairment is significant,with spine and hip involvement,and is predominantly seen in the younger age group.Total hip arthroplasty(THA)for fused hips with stiff spines in AS results in considerable improvement of mobility and function.Spine stiffness associated with AS needs evaluation before THA.Preoperative assessment with lateral spine radiographs shows loss of lumbar lordosis.Spinopelvic mobility is reduced with change in sacral slope from sitting to standing less than 10 degrees conforming to the stiff pattern.Care should be taken to reduce acetabular component anteversion at THA in these fused hips,as the posterior pelvic tilt would increase the risk of posterior impingement and anterior dislocation.Fused hips require femoral neck osteotomy,true acetabular floor identification and restoration of the hip center with horizontal and vertical offset to achieve a good functional outcome.Cementless and cemented fixation have shown comparable long-term results with the choice dependent on bone stock at THA.Risks at THA in AS include intraoperative fractures,dislocation,heterotopic ossification,among others.There is significant improvement of functional scores and quality of life following THA in these deserving young individuals with fused hips and spine stiffness. | Anil Thomas Oommen Triplicane Dwarakanathan Hariharan Viruthipadavil John Chandy Pradeep MathewPoonnoose Arun Shankar A Roncy Savio Kuruvilla Jozy Timothy | 2021 | World Journal of Orthopedics2021,12,12: | 2 |
| 3 | 碱炉高效运行与维护实践显示文摘随着当前能源需求量的急速增长以及对环保要求的不断增强,造纸厂已经将安全和环保问题纳入到方针和行动的各个方面,如造纸厂着力于探索一些能够增强碱炉安全、环保、高效、高开机率的全局性改善措施。探索实践的内容如:熔融物抽取系统、自动清理风口系统、利用安全检修平台进行检修、有味气体的处理和焚烧、先进的工艺控制、先进的安全联锁等都在本文中有相关介绍。 | 于英民 Chandrasekaran R Arun A Mishra Anshul Raju R Ravishangar P S | 2013 | 中华纸业2013,34,14: | 2 |
| 4 | Hydroxyurea treatment of sickle cell anemia in hospital - based practices 显示文摘 | Ferguson RP Arun A Carter C | 2002 | Am J Hematol2002,70,: | 1 |
| 5 | A technical review on nonalcoholic fatty liver disease显示文摘 | ARUN J SANYAL A G | 2002 | Gastroenterology2002,123,: | 1 |
| 6 | Economic incentives for agricultural nonpoint source pollution control显示文摘 | Bruce A L Marc R | 1994 | Water Resources Bulletin1994,30,3: | 1 |
| 7 | Tensile and elastic properties of tri-block copolymer based on aramide end-segments and po!yethermid- segments显示文摘 | Arun A Gaymans R J | 2009 | Journal of Applied Polymer Science2009,111,4: | 1 |
| 8 | Industrial ecology framework for achieving cleaner production in the mining and minerals industry 显示文摘 | Arun J B Dirk J A van Z | 2006 | Journal of Cleaner Production2006,,34: | 1 |
| 9 | Phosphate solubilizing bacteria from subtropical soil and their tricalcium phosphate solubilizing abilities显示文摘 | CHEN Y P REKHA P D ARUN A B | 2006 | Applied Soil Ecology2006,34,1: | 1 |
| 10 | Superhard nanocomposite coatings of TiN/Si3N4 prepared by reactive direct current unbalanced magnetron sputtering 显示文摘 | Harish C Barshilia Deepthi B Arun Prabhu A S | 2006 | Surface and Coatings Technology2006,201,12: | 1 |
| 11 | Phosphate solubilizing bacteria from subtropical soil and their tricalcium phosphate solubilizing abilities显示文摘 | Chen Y P Rekha P D Arun A B | 2006 | Applied Soil Ecology2006,34,1: | 1 |
| 12 | Perceptions of Incompatibility in Customer-to-Customer Interactions:Examining Individual Level Differences显示文摘 | RAAJPOOT N A ARUN S | 2006 | Journal of Services Marketing2006,20,5: | 1 |
| 13 | Breeding crops for reduced-tillage management in the intensive,rice-wheat systems of South Asia显示文摘 | JOSHI A K CHAND R ARUN B | 2007 | Euphytica2007,153,: | 1 |
| 14 | Correlation for cylinder-to-bed heat transfer in aerated vibrated beds of small particles 显示文摘 | ECCLES E R MUJUMDAR A ARUN S | 1992 | Drying Technology1992,10,1: | 1 |
| 15 | Feasibility of Video Capsule Endoscopy in the Management of Children With Peutz-Jeghers Syndrome: A Blinded Comparison With Barium Enterography for the Detection of Small Bowel Polyps显示文摘 | Aymer Postgate Warren Hyer Robin Phillips Arun Gupta David Burling Clive Bartram Michelle Marshall Stuart Taylor Gregor Brown Gill Schofield Paul Bassett Christine Spray Aine Fitzpatrick Chris Fraser A Latchford | 2009 | Journal of Pediatric Gastroenterology and Nutrition2009,,4: | 1 |
| 16 | Cloud Computing-A Classification,Business Models,and Research Directions显示文摘 | CHRISTOF W ARUN A BENJAMIN B | 2009 | Business&Information Systems Engineering2009,1,5: | 1 |
| 17 | Study in sexuality of medical college students in India显示文摘 | Omprakash A Arun KS Pragti C | 2000 | Journal of Adolescent Health2000,26,: | 1 |
| 18 | Application of Phase Change Materials in Thermal Management of Electronies显示文摘 | Kandasarny A Ravi Wang Xiang-Qi Mujumdar Arun S | 2007 | Applied Thermal Engineering2007,27,: | 1 |
| 19 | QROCK: a quick version of the ROCK algorithm for clustering of cate- gorical data 显示文摘 | Dutta M Dakoti Mahanto A Pujari Arun K | 2005 | Pattern Recognition Letters2005,26,15: | 1 |
| 20 | Polycyclic aromatic hydrocarbons (PAHs) biodegradation by basidiomycetes fungi, pseudomonas isolate, and theircocuhures: Comparative in vivo and in silico approach 显示文摘 | ARUN A RAJA P P ARTHI R | 2008 | Applied Biochemistry and Biotechnology2008,151,23: | 1 |