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34篇 您的检索式:作者名="Asleh"
    题名 作者 年代 出处 被引量
1Genetieally determined heterogeneity in hemoglobin scavenging and susceptibility to diabetic cardiovascular disease显示文摘Asleh R Marsg S Shilkrut M 0,,:1
2Poor lysosomal membrane integrity in proximal tubule cells of haptoglobin 2-2 genotype mice with diabetes mellitus显示文摘Asleh R Nakhoul FM Miller-Lotan R 0,,4:1
3Haptoglobin: basic and clinical aspects显示文摘Levy AP Asleh R Blum S 2010Antioxid Redox Signal2010,12,2:1
4Genetically determined heterogeneity in hemoglobin scavenging and susceptibility to diabetic cardiovascular disease 显示文摘Asleh R Marsh S Shilkrut M 2003Circ Res2003,92,11:1
5Correction of HDL dysfunction in individuals with Diabetes and the Haptoglobin 2-2 genotype显示文摘Asleh R Blum S Kalet-Litman S 2008Diabetes2008,57,:1
6Genetically determined heterogeneity in hemoglobin scavenging and susceptibility to diabetic cardiovascular disease显示文摘Asleh R Marsh S Shilkrut M 0,,11:1
7Genetically determined heterogeneity in hemoglobin scavenging and susceptibility to diabetic cardiovascular disease显示文摘Asleh R Marsh S Shilkrut M 2003Circ Res2003,92,11:1
8Haptoglobin polymorphism predicts 30-day mortalityand heart failure in patients with diabetes and acute myocardial infarction 显示文摘Suleiman M Aronson D Asleh R 2005Diabetes2005,54,9:1
9In vivo and in vitro studies establishing haptoglobin as a major susceptibility gene for diabetic vascular disease显示文摘Asleh R Levy A P 2005Vasc Health Rish Manaq2005,1,1:1
10Genetically determined heterogeneity in hemoglobin scavenging and susceptibility to diabetic cardiovascular disease显示文摘Asleh R Marsh S Shilkrut M 2003Circ Res2003,92,:1
11Haptoglobin genotype-and Diabetes-dependent differences in iron-mediated oxidative stress in vitro and in vivo显示文摘Asleh R Guetta J Levy AP 2005Circ Res2005,96,:1
12Haptoglobln polymorphism predicts 30-day mortality and heart failure in patients with diabetes and acute myocardial infarction 显示文摘Suleiman M Aronson D Asleh R 2005Diabetes2005,54,9:1
13Haptoglobin polymorphism predicts 30-day mortality and heart failure in patients with diabetes and acute myocardial infarction 显示文摘Suleiman M Aronson D Asleh R 2005Diabetes2005,54,9:1
14Haptoglobin: basic and clini- cal aspects 显示文摘Levy AP Asleh R Blum S 2010Antioxid Redox Signal2010,12,:1
15Haptoglobin polymorphism predicts 30-day mortality and heart failure in patients with diabetes and acute myocardial infarction显示文摘Suleiman M Aronson D Asleh R 2005Diabetes2005,54,:1
16Vitamin E and diabetic nephropathy in mice model and humans显示文摘Diabetes mellitus(DM) is associated with increased oxidative stress due to elevated glucose levels in the plasma. Glucose promotes glycosylation of both plasma and cellular proteins with increased risk for vascular events. Diabetic patients suffer from a higher incidence of cardiovascular complications such as diabetic nephropathy. Haptoglobin(Hp) is an antioxidant plasma protein which binds free hemoglobin, thus preventing heme-iron mediated oxidation. Two alleles exist at the Hp gene locus(1 and 2) encoding three possible Hp genotypes that differ in their antioxidant ability, and may respond differently to vitamin E treatment. Several clinical studies to have shown that Hp 1-1 genotype is a superior antioxidant to the Hp 2-2 genotype and Hp 2-2 genotype is associated with a higher incidence ofcardiovascular disease. Vitamin E was found to have beneficial effect in patient and mice with Hp 2-2 genotype. In this review we have summarized the results of our studies in patients with diabetic nephropathy treated with vitamin E and in diabetic mice with different haptoglobin genotypes.Nakhoul Farid Dahan Inbal Nakhoul Nakhoul Farber Evgeny Rachel Miller-Lotan Andrew P Levy Asleh Rabea 2013World Journal of Nephrology2013,2,4:1
17Haptoglobin:basic and clini-cal aspects显示文摘Levy AP Asleh R Blum S 2010Antioxid Redox Signal2010,12,2:1
18In vivo and in vitro studies establishing hap-toglobin as a major susceptibility gene for diabetic vascular dis-ease显示文摘Asleh R Levy AP 2005Vasc Health Risk Manag2005,1,1:1
19Haptoglobin: basic andclinical aspects 显示文摘Levy AP Asleh R Blum S 2010Antioxid Redox Signal2010,12,2:1
20Poor lysoso- mal membrane integrity in proximal tubule cells of hapto- globin 2- 2 genotype mice with diabetes mellitus显示文摘Asleh R Nakhoul FM Miller-Lotan R 2012Free Radic Biol Med2012,53,4:1
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