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| 1 | The Plant Vascular System: Evolution, Development and Functions显示文摘The emergence of the tracheophyte-based vascular system of land plantshad major impacts on the evolution of terrestrial biology, in general,through its role in facilitating the development of plants with increasedstature, photosynthetic output, and ability to colonize a greatly expandedrange of environmental habitats. Recently, considerable progress hasbeen made in terms of our understanding of the developmental andphysiological programs involved in the formation and function of theplant vascular system. In this review, we first examine the evolutionaryevents that gave rise to the tracheophytes, followed by analysis of thegenetic and hormonal networks that cooperate to orchestrate vasculardevelopment in the gymnosperms and angiosperms. The two essentialfunctions performed by the vascular system, namely the delivery of resources (water, essential mineralnutrients, sugars and amino acids) to the various plant organs and provision of mechanical support arenext discussed. Here, we focus on critical questions relating to structural and physiological propertiescontrolling the delivery of material through the xylem and phloem. Recent discoveries into the role ofthe vascular system as an effective long-distance communication system are next assessed in termsof the coordination of developmental, physiological and defense-related processes, at the whole-plantlevel. A concerted effort has been made to integrate all these new findings into a comprehensive pictureof the state-of-the-art in the area of plant vascular biology. Finally, areas important for future researchare highlighted in terms of their likely contribution both to basic knowledge and applications to primaryindustry. | William J. Lucas Andrew Groover Raffael Lichtenberger Kaori Furuta Shri-Ram Yadav Yk Helariutta Xin-Qiang He Hiroo Fukuda Julie Kang Siobhan M. Brady John W. Patrick John Sperry Akiko Yoshida Ana-Flor López-Millan Michael A. Grusak Pradeep Kachroo | 2013 | Journal of Integrative Plant Biology2013，55，4： | 30 |
| 2 | Liver disease in pregnancy显示文摘Liver diseases in pregnancy may be categorized into liver disorders that occur only in the setting of pregnancy and liver diseases that occur coincidentally with pregnancy. Hyperemesis gravidarum, preeclampsia/eclampsia, syndrome of hemolysis, elevated liver tests and low platelets (HELLP), acute fatty liver of pregnancy, and intrahepatic cholestasis of pregnancy are pregnancy-specific disorders that may cause elevations in liver tests and hepatic dysfunction. Chronic liver diseases, including cholestatic liver disease, autoimmune hepatitis, Wilson disease, and viral hepatitis may also be seen in pregnancy. Management of liver disease in pregnancy requires collaboration between obstetricians and gastroenterologists/hepatologists. Treatment of pregnancy-specific liver disorders usually involves delivery of the fetus and supportive care, whereas management of chronic liver disease in pregnancy is directed toward optimizing control of the liver disorder. Cirrhosis in the setting of pregnancy is less commonly observed but offers unique challenges for patients and practitioners. This article reviews the epidemiology, pathophysiology, diagnosis, and management of liver diseases seen in pregnancy. | Noel M Lee Carla W Brady | 2009 | World Journal of Gastroenterology2009，15，8： | 13 |
| 3 | Role of small bowel capsule endoscopy in the diagnosis and management of iron deficiency anemia in elderly: A comprehensive review of the current literature显示文摘Iron deficiency anemia(IDA)is common and often under recognized problem in the elderly.It may be the result of multiple factors including a bleeding lesion in the gastrointestinal tract.Twenty percent of elderly patients with IDA have a negative upper and lower endoscopy and two-thirds of these have a lesion in the small bowel(SB).Capsule endoscopy(CE)provides direct visualization of entire SB mucosa,which was not possible before.It is superior to push enteroscopy,enteroclysis and barium radiography for diagnosing clinically significant SB pathology resulting in IDA.Angioectasia is one of the commonest lesions seen on the CE in elderly with IDA.The diagnostic yield of CE for IDA progressively increases with advancing age,and is highest among patients over 85 years of age.Balloon assisted enteroscopy is used to treat the lesions seen on CE.CE has some limitations mainly lack of therapeutic capability,inability to provide precise location of the lesion and false positive results.Overall CE is a very safe and effective procedure for the evaluation of IDA in elderly. | Adnan Muhammad Gitanjali Vidyarthi Patrick Brady | 2014 | World Journal of Gastroenterology2014，20，26： | 11 |
| 4 | 儿童肥胖相关高血压显示文摘从1980年以来,儿童和青少年的肥胖率已经增长了将近2倍。据估计,目前在年龄2~19岁的儿童中,肥胖约占17%,如果按这个比例计算,在美国,有约1270万的肥胖儿童。如果再加上超重儿童,美国约有2500万的超重/肥胖儿童(占30%),这个数据是非常惊人的。除了这个数据本身,数据背后的意义更值得关注。肥胖儿童的心血管病风险明显增加:他们的收缩压、舒张压水平更高,发生血脂异常和胰岛素抵抗的比例更多。研究显示,有70%的肥胖儿童至少有1项心血管病危险因素,39%的肥胖儿童有≥2项的危险因素。 | Brady TM 张刘锋 | 2018 | 中华高血压杂志2018，26，1： | 11 |
| 5 | 一种在表面形成Al_2O_3膜的新型耐热奥氏体不锈钢显示文摘一类以在材料表面形成Al2O3膜的奥氏体不锈钢(AFA)的开发正如火如荼地在全球展开。这类合金与传统的、在其表面形成Cr2O3膜的不锈钢相比,在不牺牲其成本、蠕变抗力和可焊性等其它性能的同时具有更高的使用温度和更好的耐环境侵蚀能力。作者简要介绍了该合金的开发方法和其抗氧化和蠕变抗力方面的数据。 | BRADY MP YAMAMOTO Y MAZIASZ PJ SANTELLA ML 韦习成 | 2008 | 自然杂志2008，30，4： | 10 |
| 6 | Assessing the effects of quality, value, and customer satisfaction on consumer behavioral intentions in service environments显示文摘 | J.Joseph Cronin Michael K Brady G.Tomas M Hult | 2000 | Journal of Retailing2000，，2： | 7 |
| 7 | 新生儿重症监护室医院感染预防策略显示文摘新生儿是医院感染的易感人群,医院感染能增加新生儿重症监护室(NICU)患儿的患病率、死亡率,延长住院时间,增加医疗费用,本文阐述了关于新生儿医院感染的预防和管理策略。
一、手卫生
手卫生是医务人员洗手、卫生手消毒、外科手消毒的总称。手卫生是降低医院感染最有效的方法。以下情况应遵守手卫生:接触患儿前后;从患儿污染的部位到清洁部位;进行侵袭性操作之前;接触患儿体液、排泄物、破损的皮肤、伤口敷料之后;直接接触患儿周围环镜后;摘除无菌或被污染的手套后。 | 卜祥芳 张欣 Polin RA Denson S Brady MT | 2014 | 中国新生儿科杂志2014，29，6： | 7 |
| 8 | Modeling of fiber bridging in fluid flow for well stimulation applications显示文摘Accurate acid placement constitutes a major concern in matrix stimulation because the acid tends to penetrate the zones of least resistance while leaving the low-permeability regions of the formation untreated.Degradable materials(fibers and solid particles)have recently shown a good capability as fluid diversion to overcome the issues related to matrix stimulation.Despite the success achieved in the recent acid stimulation jobs stemming from the use of some products that rely on fiber flocculation as the main diverting mechanism,it was observed that the volume of the base fluid and the loading of the particles are not optimized.The current industry lacks a scientific design guideline because the used methodology is based on experience or empirical studies in a particular area with a particular product.It is important then to understand the fundamentals of how acid diversion works in carbonates with different diverting mechanisms and diverters.Mathematical modeling and computer simulations are effective tools to develop this understanding and are efficiently applied to new product development,new applications of existing products or usage optimization.In this work,we develop a numerical model to study fiber dynamics in fluid flow.We employ a discrete element method in which the fibers are represented by multi-rigid-body systems of interconnected spheres.The discrete fiber model is coupled with a fluid flow solver to account for the inherent simultaneous interactions.The focus of the study is on the tendency for fibers to flocculate and bridge when interacting with suspending fluids and encountering restrictions that can be representative of fractures or wormholes in carbonates.The trends of the dynamic fiber behavior under various operating conditions including fiber loading,flow rate and fluid viscosity obtained from the numerical model show consistency with experimental observations.The present numerical investigation reveals that the bridging capability of the fiber–fluid system can be enhanced by increasing the fiber loading,selecting fibers with higher stiffness,reducing the injection flow rate,reducing the suspending fluid viscosity or increasing the attractive cohesive forces among fibers by using sticky fibers. | Mehdi Ghommem Mustapha Abbad Gallyam Aidagulov Steve Dyer Dominic Brady | 2020 | Petroleum Science2020，17，3： | 4 |
| 9 | 移动机器人的运动预测控制显示文摘本文简要介绍了移动机器人的路径控制问题 ,并根据广义预测控制的概念提出了运动预测控制方法 ,对移动机器人非线性模型使用了中间变量及 | 谷东兵 胡豁生 Michael Brady | 2000 | 仪器仪表学报2000，21，2： | 4 |
| 10 | Molecular biological access to the chemistry of unknown soil microbes: a new frontier for natural products显示文摘 | Jo Handelsman Michelle R. Rondon Sean F. Brady Jon Clardy Robert M. Goodman | 1998 | Chemistry & Biology1998，，10： | 2 |
| 11 | Cytokine and acute pancreatitis显示文摘 | Brady M Christmas S | 1999 | Baillieres Best Pract Res Clin Gastroenterol1999，13，2： | 2 |
| 12 | Systematic review and meta‐analysis of continuous local anaesthetic wound infiltration versus epidural analgesia for postoperative pain following abdominal surgery显示文摘 | N. T. Ventham M. Hughes S. O’Neill N. Johns R. R. Brady S. J. Wigmore | 2013 | Br J Surg2013，，10： | 2 |
| 13 | Inflammatory mediators in acute pancreatitis显示文摘 | Bhatia M Brady M | 2000 | J Pathol2000，190，2： | 2 |
| 14 | Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile:A pooled analysis显示文摘BACKGROUND The diagnosis of type 2 diabetes(T2D)in younger adults,an increasingly common public health issue,is associated with a higher risk of cardiovascular complications and mortality,which may be due to a more adverse cardiovascular risk profile in individuals diagnosed at a younger age.AIM To investigate the association between age at diagnosis and the cardiovascular risk profile in adults with T2D.METHODS A pooled dataset was used,comprised of data from five previous studies of adults with T2D,including 1409 participants of whom 196 were diagnosed with T2D under the age of 40 years.Anthropometric and blood biomarker measurements included body weight,body mass index(BMI),waist circumference,body fat percentage,glycaemic control(HbA1c),lipid profile and blood pressure.Univariable and multivariable linear regression models,adjusted for diabetes duration,sex,ethnicity and smoking status,were used to investigate the association between age at diagnosis and each cardiovascular risk factor.RESULTS A higher proportion of participants diagnosed with T2D under the age of 40 were female,current smokers and treated with glucose-lowering medications,compared to participants diagnosed later in life.Participants diagnosed with T2D under the age of 40 also had higher body weight,BMI,waist circumference and body fat percentage,in addition to a more adverse lipid profile,compared to participants diagnosed at an older age.Modelling results showed that each one year reduction in age at diagnosis was significantly associated with 0.67 kg higher body weight[95%confidence interval(CI):0.52-0.82 kg],0.18 kg/m^(2) higher BMI(95%CI:0.10-0.25)and 0.32 cm higher waist circumference(95%CI:0.14-0.49),after adjustment for duration of diabetes and other confounders.Younger age at diagnosis was also significantly associated with higher HbA1c,total cholesterol,low-density lipoprotein cholesterol and triglycerides.CONCLUSION The diagnosis of T2D earlier in life is associated with a worse cardiovascular risk factor profile,compared to those diagnosed later in life. | Mary M Barker Francesco Zaccardi Emer M Brady Gaurav S Gulsin Andrew P Hall Joseph Henson Zin ZinHtike Kamlesh Khunti Gerald P McCann Emma L Redman David R Webb Emma G Wilmot Tom Yates Jian Yeo Melanie J Davies Jack A Sargeant | 2022 | World Journal of Diabetes2022，13，3： | 2 |
| 15 | SUSAN—A New Approach to Low Level Image Processing显示文摘 | Stephen M. Smith J. Michael Brady | 1997 | International Journal of Computer Vision1997，，1： | 2 |
| 16 | Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis显示文摘 | Nagendra Singh Ashish Gurav Sathish Sivaprakasam Evan Brady Ravi Padia Huidong Shi Muthusamy Thangaraju Puttur D. Prasad Santhakumar Manicassamy David H. Munn Jeffrey R. Lee Stefan Offermanns Vadivel Ganapathy | 2014 | Immunity2014，，1： | 2 |
| 17 | Laparoscopic colectomy in obese and nonobese patients显示文摘 | Anthony J. Senagore Conor P. Delaney Khaled Madboulay Karen M. Brady C. Victor W. Fazio | 2003 | Journal of Gastrointestinal Surgery2003，，4： | 2 |
| 18 | Saliency, Scale and Image Description显示文摘 | Timor Kadir Michael Brady | 2001 | International Journal of Computer Vision2001，，2： | 2 |
| 19 | Silk fibroin microtubes for blood vessel engineering显示文摘 | Michael Lovett Christopher Cannizzaro Laurence Daheron Brady Messmer Gordana Vunjak-Novakovic David L. Kaplan | 2007 | Biomaterials2007，，35： | 2 |
| 20 | Real-time corner detection algorithm for motion estimation显示文摘 | Han Wang Michael Brady | 1995 | Image and Vision Computing1995，，9： | 2 |
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