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| 1 | Assessing liver injury associated with antimycotics:Concise literature review and clues from data mining of the FAERS database显示文摘AIM: To inform clinicians on the level of hepatotoxicrisk among antimycotics in the post-marketing setting,following the marketing suspension of oral ketocon-azole for drug-induced liver injury(DILI).METHODS: The publicly available international FAERSdatabase(2004-2011) was used to extract DILI cases(including acute liver failure events), where antimycot-ics with systemic use or potential systemic absorptionwere reported as suspect or interacting agents. The re-porting pattern was analyzed by calculating the report-ing odds ratio and corresponding 95%CI, a measure ofdisproportionality, with time-trend analysis where ap-propriate.RESULTS: From 1687284 reports submitted over the8-year period, 68115 regarded liver injury. Of these,2.9% are related to antimycotics(1964 cases, of which 112 of acute liver failure). Eleven systemic antimycotics(including ketoconazole and the newer triazole deriva-tives voriconazole and posaconazole) and terbinafine(used systemically to treat onychomicosis) generated a significant disproportionality, indicating a post-market-ing signal of risk.CONCLUSION: Virtually all antimycotics with systemic action or absorption are commonly reported in clinically significant cases of DILI. Clinicians must be aware of this aspect and monitor patients in case switch is con-sidered, especially in critical poly-treated patients under chronic treatment. | Emanuel Raschi Elisabetta Poluzzi Ariola Koci Paolo Caraceni Fabrizio De Ponti | 2014 | World Journal of Hepatology2014，6，8： | 10 |
| 2 | Serum α-fetoprotein for diagnosis of hepatocellular carcinoma in patients with chronic liver disease: influence of HBsAg and anti-HCV status显示文摘 | Franco Trevisani Paola Emanuela D’Intino Antonio Maria Morselli-Labate Giuseppe Mazzella Esterita Accogli Paolo Caraceni Marco Domenicali Stefania De Notariis Enrico Roda Mauro Bernardi | 2001 | Journal of Hepatology2001，，4： | 3 |
| 3 | The role of the endocannabinoid system in liver diseases 显示文摘 | Caraceni P Domenicali M Giannone F | 2009 | Baillieres Best Pract Res Clin Endocrinol Metab2009，23，1： | 1 |
| 4 | An international survey of cancer pain characteristics and syndromes显示文摘 | Caraceni A Russell K | 1999 | Pain1999，82，： | 1 |
| 5 | The reduced tolerance of rat fatty liver to ischemia reperfusion is associated with mitochondrial oxidative injury 显示文摘 | Caraceni P Domenicali M Vendemiale G | 2005 | J Surg Res2005，124，2： | 1 |
| 6 | The role of the endocannabinoid system in liver diseases 显示文摘 | Caraceni P Domenicali M Giannone F | 2009 | Baillieres BestPract Res Clin Endocrinol Metab2009，23，1： | 1 |
| 7 | Transthoracic electricalbi oimpedance:a non-invasive technique for the evaluation of the haemodynamic alterations in patients with liver cirrhosis显示文摘 | Dazzani F Micati M Caraceni P | | 0，，10： | 1 |
| 8 | A validation study of the WHO method for cancer pain relief 显示文摘 | Ventafridda V Tamburini M Caraceni A | 1987 | Cancer1987，59，4： | 1 |
| 9 | Transthoracic electrical bioimpedance:a non-invasive technique for the evaluation of thehaemodynamic alterations in patients with liver cirrhosis显示文摘 | Dazzani F Micati M Caraceni P | 2005 | Dig Liver Dis2005，37，10： | 1 |
| 10 | Use of opioid analgesics in the treatment of cancer pain: evidence-based recommendations from the EAPC显示文摘 | Caraceni A Hanks G Kaasa S | 2012 | Lancet Oncol2012，13，2： | 1 |
| 11 | Studies Comparing Numerical Rating Scales, Verbal Rating Scales, and Visual Analogue Scales for Assessment of Pain Intensity in Adults: A Systematic Literature Review显示文摘 | Marianne Jensen Hjermstad Peter M. Fayers Dagny F. Haugen Augusto Caraceni Geoffrey W. Hanks Jon H. Loge Robin Fainsinger Nina Aass Stein Kaasa | 2011 | Journal of Pain and Symptom Management2011，，6： | 1 |
| 12 | Sensitivity, specifici- ty,and clinical value of human papillomavirus ( HPV ) E6/E7 mRNA assay as a triage test for cervical cytology and HPV DNA test 显示文摘 | Benevolo M Vocaturo A Caraceni D | 2011 | J Clin Microbio12011，49，7： | 1 |
| 13 | Posttranscriptional changes of serum albumin: Clinical and prognostic significance in hospitalized patients with cirrhosis显示文摘 | Marco Domenicali Maurizio Baldassarre Ferdinando A Giannone Marina Naldi Marianna Mastroroberto Maurizio Biselli Maristella Laggetta Daniela Patrono Carlo Bertucci Mauro Bernardi Paolo Caraceni | 2014 | Hepatology2014，，6： | 1 |
| 14 | Increased generation of reactive oxygen species in isolated rat fatty liver during postischemic reoxygenation 显示文摘 | Nardo B Caraceni P Pasini P | 2001 | Transplantation2001，71，12： | 1 |
| 15 | Conversion ratios for opioidswitching in the treatment of cancer pain: a systematic re-view 显示文摘 | Mercadante S Caraceni A | 2011 | Palliat Med2011，25，5： | 1 |
| 16 | Prophylaxis and treatment of hepatitis B in immunocompromised patients显示文摘 | A. Marzano E. Angelucci P. Andreone M. Brunetto R. Bruno P. Burra P. Caraceni B. Daniele V. Di Marco F. Fabrizi S. Fagiuoli P. Grossi P. Lampertico R. Meliconi A. Mangia M. Puoti G. Raimondo A. Smedile | 2006 | Digestive and Liver Disease2006，，5： | 1 |
| 17 | cardio electrophysiological abnormalities in patients with cirrosis 显示文摘 | Zambruni A Trevisani F Caraceni P | 2006 | J Hepatol2006，44，5： | 1 |
| 18 | cardio electrophysi ologicaI abnormalities in patients with cirrosis显示文摘 | Zambruni A Trevisani F Caraceni P | 2006 | J Hepatol2006，44，5： | 1 |
| 19 | Use of opioid analgesics in the treatment of cancer pain:evidencebased recommendations from the EAPC显示文摘 | Caraceni A Hanks G Kaasa S | 2012 | Lancet Oncol2012，13，2： | 1 |
| 20 | Use of opioid analgesics in the treatmenl of cancer pain: evidence-based recommendations from the EAPC 显示文摘 | Caraceni A Hanks G Kaasa S | 2012 | Lancet Onco12012，13，2： | 1 |
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