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| 1 | ERCP in acute pancreatitis:What takes place in routine clinical practice?显示文摘AIM:To evaluate the data from a survey carried out in Italy regarding the endoscopic approach to acute pancreatitis in order to obtain a picture of what takes place after the release of an educational project on acute pancreatitis sponsored by the Italian Association for the Study of the Pancreas.METHODS:Of the 1 173 patients enrolled in our survey,the most frequent etiological category was biliary forms(69.3%) and most patients had mild pancreatitis(85.8%).RESULTS:344/1 173(29.3%) underwent endoscopic retrograde cholangiopancreatography(ERCP).The mean interval between the onset of symptoms and ERCP was 6.7 ± 5.0 d;only 89 examinations(25.9%) were performed within 72 h from the onset of symptoms.The main indications for ERCP were suspicion of common bile duct stones(90.3%),jaundice(44.5%),clini cal worsening of acute pancreatitis(14.2%) and cho langitis(6.1%).Biliary and pancreatic ducts were visua lized in 305 patients(88.7%) and in 93 patients(27.0%) respectively.The success rate in obtaining a cholangio gram was statistically higher(P = 0.003) in patients with mild acute pancreatitis(90.6%) than in patients with severe disease(72.2%).Biliary endoscopic sphinc terotomy was performed in 295 of the 305 patients(96.7%) with no difference between mild and severe disease(P = 0.985).ERCP morbidity was 6.1% and mortality was 1.7%;the mortality was due to the complications of acute pancreatitis and not the endoscopic procedure.CONCLUSION:The results of this survey,as with those carried out in other countries,indicate a lack of compliance with the guidelines for the indications for interventional endoscopy. | Armando Gabbrielli Raffaele Pezzilli Generoso Uomo Alessandro Zerbi Luca Frulloni Paolo De Rai Laura Castoldi Guido Costamagna Claudio Bassi Valerio Di Carlo | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，9： | 14 |
| 2 | Negative capsule endoscopy in patients with obscure gastrointestinal bleeding reliable: Recurrence of bleeding on long-term follow-up显示文摘AIM: To assess the rate of recurrent bleeding of the small bowel in patients with obscure bleeding already undergone capsule endoscopy (CE) with negative results. METHODS: We reviewed the medical records related to 696 consecutive CE performed from December 2002 to January 2011, focusing our attention on patients with recurrence of obscure bleeding and negative CE. Evaluating the patient follow-up, we analyzed the recurrence rate of obscure bleeding in patient with a negative CE. Actuarial rates of rebleeding during follow-up were calculated, and factors associated with rebleeding were assessed through an univariate and multivariate analysis. A P value of less than 0.05 was regarded as statistically significant. The sensitivity, specificity, and positive and negative predictive values (PPV and NPV) of negative CE were calculated. RESULTS: Two hundred and seven out of 696 (29.7%) CE studies resulted negative in patient with obscure/overt gastrointestinal bleeding. Overall, 489 CE (70.2%) were positive studies. The median follow-up was 24 mo (range 12-36 mo). During follow-up, recurrence of obscure bleeding was observed only in 34 out of 207 negative CE patients (16.4%); 26 out of 34 with obscure overt bleeding and 8 out of 34 with obscure occult bleeding. The younger age (< 65 years) and the onset of bleeding such as melena are independent risk factors of rebleeding after a negative CE (OR = 2.6703, 95%CI: 1.1651-6.1202, P = 0.0203; OR 4.7718, 95%CI: 1.9739-11.5350, P = 0.0005). The rebleeding rate (CE+ vs CE-) was 16.4% vs 45.1% (χ 2 test, P = 0.00001). The sensitivity, specificity, and PPV and NPV were 93.8%, 100%, 100%, 80.1%, respectively. CONCLUSION: Patients with obscure gastrointestinal bleeding and negative CE had a significantly lower rebleeding rate, and further invasive investigations can be deferred. | Maria Elena Riccioni Riccardo Urgesi Rossella Cianci Gianluca Rizzo Luca D'Angelo Riccardo Marmo Guido Costamagna | 2013 | World Journal of Gastroenterology2013，19，28： | 14 |
| 3 | Capsule endoscopy in celiac disease显示文摘Video capsule endoscopy is an attractive and patient- friendly tool that provides high quality images of the small bowel. Obscure gastrointestinal bleeding is the primary and most evaluated indication to capsule endoscopy;however,indications are expanding and a small number of preliminary reports have been presented concerning the role of video capsule endoscopy in the diagnosis of celiac disease. The purpose of this review is to update the current knowledge and to hypothesize on future perspectives of the use of video capsule endoscopy in patients with celiac disease. | Cristiano Spada Maria Elena Riccioni Riccardo Urgesi Guido Costamagna | 2008 | World Journal of Gastroenterology2008，14，26： | 8 |
| 4 | 冒号囊内视镜检查法: 优点,限制和期望哪个新奇?显示文摘 Since the first reports almost ten years ago, wireless capsule endoscopy has gained new f ields of application. Colon capsule endoscopy represents a new diagnostic technology for colonic exploration. Clinical trials have shown that colon capsule endoscopy is feasible, accurate and safe in patients suffering from colonic diseases and might be a valid alternative to conventional colonoscopy in selected cases such as patients refusing conventional colonoscopy or with contraindications to colonoscopy or when colonoscopy is incomplete. Despite the enthusiasm surrounding this new technique, few clinical and randomized controlled trials are to be found in the current literature, leading to heterogeneous or controversial results. Upcoming studies are needed to prove the substantial utility of colon capsule endoscopy for colon cancer screening, especially in a low prevalence of disease population, and for other indications such as inflammatory bowel disease. Possible perspectives are critically analysed and reported in this paper. | Maria Elena Riccioni Riccardo Urgesi Rossella Cianci Alessandra Bizzotto Cristiano Spada Guido Costamagna | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，4： | 7 |
| 5 | Current status of device-assisted enteroscopy: Technical matters, indication, limits and complications显示文摘Enteroscopy, defined as direct visualization of the smallbowel with the use of a fiberoptic or capsule endoscopy, has progressed considerably over the past severalyears. The need for endoscopic access to improvediagnosis and treatment of small bowel disease hasled to the development of novel technologies one ofwhich is noninvasive, the video capsule, and a type of invasive technique, the deviceassisted enteroscopy.In particular, the device-assisted enteroscopy consiststhen of three different types of instruments all able toallow, in skilled hands, to display partially or throug-hout its extension (if necessary) the small intestine.Newer devices, double balloon, single balloon and spiral endoscopy, are just entering clinical use. The aim of this article is to review recent advances in small bowelenteroscopy, focusing on indications, modifications toimprove imaging and techniques, pitfalls, and clinical applications of the new instruments. With new technologies, the trials and tribulations of learning new endo-scopic skills and determining their role in the diagnosisand treatment of small bowel disease come. Identification of small bowel lesions has dramatically improved.Studies are underway to determine the best strategy toapply new enteroscopy technologies for the diagnosisand management of small bowel disease, particularly obscure bleeding. Vascular malformations such as angiectasis and small bowel neoplasms as adenocar cinomaor gas trointestinal stromal tumors. Complete entero-scopy of the small bowel is now possible. However, because of the length of the small bowel, endoscopic examination and the rapeutic maneuvers require significant skill, radiological assistance, the use of deep sedation with the assistance of the anesthetist. Prospective ran-domized studies are needed to guide diagnostic testing and the rapy with these new endoscopic techniques. | Riccioni Maria Elena Urgesi Riccardo Cianci Rossella Alessandra Bizzotto Galasso Domenico Costamagna Guido | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，10： | 5 |
| 6 | Endoscopic treatment of chronic pancreatitis: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline显示文摘 | J.-M. Dumonceau M. Delhaye A. Tringali J. Dominguez-Munoz J.-W. Poley M. Arvanitaki G. Costamagna F. Costea J. Devière P. Eisendrath S. Lakhtakia N. Reddy P. Fockens T. Ponchon M. Bruno | 2012 | Endoscopy2012，，08： | 5 |
| 7 | The role of K- ras gene mutation analysis in EUS-guided FNA cytology specimens for the differential diagnosis of pancreatic solid masses: a meta-analysis of prospective studies显示文摘 | Lorenzo Fuccio Cesare Hassan Liboria Laterza Loredana Correale Nico Pagano Paolo Bocus Carlo Fabbri Antonella Maimone Vincenzo Cennamo Alessandro Repici Guido Costamagna Franco Bazzoli Alberto Larghi | 2013 | Gastrointestinal Endoscopy2013，，： | 4 |
| 8 | Feasibility and yield of a novel 22-gauge histology EUS needle in patients with pancreatic masses: a multicenter prospective cohort study显示文摘 | Alberto Larghi Julio Iglesias-Garcia Jan-Werner Poley Geneviève Monges Maria Chiara Petrone Guido Rindi Ihab Abdulkader Paolo Giorgio Arcidiacono Guido Costamagna Katharina Biermann Erwan Bories Claudio Doglioni J. Enrique Dominguez-Mu?oz Cesare Hassan Ma | 2013 | Surgical Endoscopy2013，，10： | 3 |
| 9 | Successful endoscopic closure of a lateral duodenal perforation at ERCP with fibrin glue显示文摘 | Massimiliano Mutignani Federico Iacopini Stefanos Dokas Alberto Larghi Pietro Familiari Andrea Tringali Guido Costamagna | 2006 | Gastrointestinal Endoscopy2006，，4： | 2 |
| 10 | Efficacy of Endoscopic Closure of Acute Perforations of the Gastrointestinal Tract显示文摘 | Rogier P. Voermans Olivier Le Moine Daniel von Renteln Thierry Ponchon Marc Giovannini Marco Bruno Bas Weusten Stefan Seewald Guido Costamagna Pierre Deprez Paul Fockens | 2012 | Clinical Gastroenterology and Hepatology2012，，6： | 2 |
| 11 | Combined endoscopic stent insertion in malignant biliary and duodenal obstruction显示文摘 | M. Mutignani A. Tringali S. Shah V. Perri P. Familiari F. Iacopini C. Spada G. Costamagna | 2007 | Endoscopy2007，，： | 2 |
| 12 | Colon capsule endoscopy:What we know and what we would like to know显示文摘Colonoscopy is usually perceived as an invasive and potentially painful procedure,being also affected by a small,but definite,risk of major complications(cardiopulmonary complications,perforation,hemorrhage)and even mortality.To improve both acceptability and safety,Pill Cam Colon Capsule Endoscopy(CCE)(Given Imaging Ltd,Yoqneam,Israel)has been developed.CCE represents a non-invasive technique that is able to explore the colon without sedation and air insufflation.The Second Generation of Colon Capsule Endoscopy(Pill Cam Colon 2)(CCE-2)was proven to be an accurate tool to detect colonic neoplastic lesions when used in average risk individuals.To date,the evidence supports the use of CCE-2 in case of colonoscopy failure,in patients unwilling to perform colonoscopy and when colonoscopy is contraindicated.Other potential applications,such as colorectal cancer screening or diagnostic surveillance ofinflammatory bowel disease need to be clarified.In this paper,the current'state of the art',potential application of CCE and future needs are evaluated. | Cristiano Spada Federico Barbaro Gianluca Andrisani Leonardo Minelli Grazioli Cesare Hassan Isabella Costamagna Mariachiara Campanale Guido Costamagna | 2014 | World Journal of Gastroenterology2014，20，45： | 2 |
| 13 | Endoscopic retrieval of a duodenal perforating teaspoon显示文摘Foreign objects ingestion occur commonly in pediatric patients. The majority of ingested foreign bodies pass spontaneously the gastrointestinal tract and surgery is rarely required for extraction. Endoscopic removal of foreign bodies larger than 10 cm has not yet been described. We present the case of a 16 years old bulimic girl that swallowed a 12 cm long teaspoon in order to provoke vomiting. The teaspoon perforated the duodenum. However, it was removed during gastroscopy and the site of perforation was closed endoscopically. This particular case shows the importance of endoscopy for retrieval of large foreign bodies, and the possibility to endoscopically close a perforated duodenal wall. | Ivo Bokoski Andrea Tringali Rosario Landi Pietro Familiari Anna Chiara Iolanda Contini Claudio Pintus Guido Costamagna | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，4： | 2 |
| 14 | A prospective trial comparing small bowel radiographs and video capsule endoscopy for suspected small bowel disease显示文摘 | Guido Costamagna Saumil K. Shah Maria Elena Riccioni Francesca Foschia Massimiliano Mutignani Vincenzo Perri Amorino Vecchioli Maria Gabriella Brizi Aurelio Picciocchi Pasquale Marano | 2002 | Gastroenterology2002，，4： | 2 |
| 15 | Management of duodeno-pancreato-biliary perforations after ERCP: outcomes from an Italian tertiary referral center显示文摘 | Sergio Alfieri Fausto Rosa Caterina Cina Antonio Pio Tortorelli Andrea Tringali Vincenzo Perri Guido Costamagna Giovanni Battista Doglietto | 2013 | Surgical Endoscopy2013，，6： | 2 |
| 16 | European Society of Gastrointestinal Endoscopy (ESGE): Recommendations (2009) on clinical use of video capsule endoscopy to investigate small-bowel, esophageal and colonic diseases显示文摘 | S. Ladas K. Triantafyllou C. Spada M. Riccioni J.-F. Rey Y. Niv M. Delvaux R. de Franchis G. Costamagna | 2010 | Endoscopy2010，，03： | 2 |
| 17 | 一种新颖的诊断小肠通畅功能的工具:应用设定的开放式胶囊 | Spada C. Spera G. Riccioni M. G. Costamagna 王铮 | 2005 | 世界核心医学期刊文摘(胃肠病学分册)2005，0，12： | 2 |
| 18 | Agile patency system eliminates risk of capsule retention in patients with known intestinal strictures who undergo capsule endoscopy显示文摘 | Juan M. Herrerias Jonathan A. Leighton Guido Costamagna Anthony Infantolino Rami Eliakim Doron Fischer David T. Rubin Howard D. Manten Eitan Scapa Douglas R. Morgan Ari J. Bergwerk Binyamin Koslowsky Samuel N. Adler | 2008 | Gastrointestinal Endoscopy2008，，6： | 2 |
| 19 | Comparison of two dosing regimens of gabexate in the prophylaxis of post-ERCP pancreatitis显示文摘 | Enzo Masci Giorgio Cavallini Alberto Mariani Luca Frulloni Pier Alberto Testoni Simona Curioni Alberto Tittobello Generoso Uomo Guido Costamagna Sandro Zambelli Gianpiero Macarri Paolo Innocenti Carola Dragonetti | 2003 | The American Journal of Gastroenterology2003，，10： | 2 |
| 20 | 多支架治疗慢性重症胰腺炎中难治性胰管狭窄的远期疗效显示文摘Background and Study Aims:Dominant pancreatic duct strictures located in the head of the pancreas in patients with severe chronic pancreatitis are often managed by endoscopic placement of a single plastic stent.Patients with refractory strictures after prolonged stenting require repeated stent replacement or surgical pancreaticojejunostomy.Placement of multiple plastic stents has proved effective in managing postoperative biliary strictures.The aim of this study was to investigate the feasibility,efficacy,and long-term results of multiple stenting of refractory pancreatic strictures in severe chronic pancreatitis.Patients and Methods:19 patients with severe chronic pancreatitis(16 men,three women;mean age 45 years)and with a single pancreatic stent through a refractory dominant stricture in the pancreatic head underwent the following protocol:(i)removal of the single pancreatic stent;(ii)balloon dilation of the stricture;(iii)insertion of the maximum number of stents allowed by the stricture tightness and the pancreatic duct diameter;and(iv)removal of stents after 6 to 12 months.Results:The median number of stents placed through the major or minor papilla was 3,with diameters ranging from 8.5 to 11.5 Fr and length from 4 to 7 cm.Only one patient(5.5%)had persistent stricture after multiple stenting.During a mean follow-up of 38 months after removal,84%of patients were asymptomatic,and 10.5%had symptomatic stricture recurrence.No major complications were recorded.Conclusion:Endoscopic multiple stenting of dominant pancreatic duct strictures in chronic pancreatitis is a feasible and safe technique.Multiple pancreatic stenting is promising in obtaining persistent stricture dilation on long-term follow-up in the setting of severe chronic pancreatitis. | Costamagna G. Bulajic M. Tringali A. 孟欣颖 | 2006 | 世界核心医学期刊文摘(胃肠病学分册)2006，2，9： | 2 |
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