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| 1 | Prostate cancer in Asia:A collaborative report显示文摘The incidence of prostate cancer(PCa)within Asian population used to be much lower than in the Western population;however,in recent years the incidence and mortality rate of PCa in some Asian countries have grown rapidly.This collaborative report summarized the latest epidemiology information,risk factors,and racial differences in PCa diagnosis,current status and new trends in surgery management and novel agents for castration-resistant prostate cancer.We believe such information would be helpful in clinical decision making for urologists and oncologists,health-care ministries and medical researchers. | Rui Chen Shancheng Ren 无 Ming Kwong Yiu Ng Chi Fai Wai Sam Cheng Lap Hong Ian Seiji Naito Tadashi Matsuda Elijah Kehinde Ali Kural Jason Yichun Chiu Rainy Umbas Qiang Wei Xiaolei Shi Liqun Zhou Jian Huang Yiran Huang Liping Xie Lulin Ma Changjun Yin Danfeng Xu Kexin Xu Zhangqun Ye Chunxiao Liu Dingwei Ye Xin Gao Qiang Fu Jianquan Hou Jianlin Yuan Dalin He Tiejun Pan Qiang Ding Fengshuo Jin Benkang Shi Gongxian Wang Xiuheng Liu Dongwen Wang Zhoujun Shen Xiangbo Kong Wanhai Xu Yaoliang Deng Haibo Xia Alexa NCohen Xu Gao Chuanliang Xu Yinghao Sun | 2014 | Asian Journal of Urology2014，1，1： | 13 |
| 2 | Feedback Regulation of FLC by FLOWERING LOCUS T (FT) and FD through a 5’ FLC Promoter Region in Arabidopsis显示文摘Dear Editor, Recently, it was reported that the florigenic FT protein bound to a 3’ region of the potent floral repressor FLC (FLOWERING LOCUS C) to activate the expression of long noncoding antisense RNAs known as COOLAIR and consequently repress FLC expression to control flowering time and seed dormancy in Arabidopsis (Chen and Penfield, 2018). Here, we show that FT represses FLC expression through a 5' promoter region, but not COOLAIR. | Xiao Luo Tao Chen Xiaolin Zeng Dingwei He Yuehui He | 2019 | Molecular Plant2019，12，3： | 10 |
| 3 | Shale Gas Formation and Occurrence in China: An Overview of the Current Status and Future Potential显示文摘Shale gas is one of the most promising unconventional resources both in China and abroad. It is known as a form of self-contained source-reservoir system with large and continuous dimensions. Through years of considerable exploration efforts, China has identified three large shale gas fields in the Fuling, Changning and Weiyuan areas of the Sichuan Basin, and has announced more than 540 billion m^3 of proven shale gas reserves in marine shale systems. The geological theories for shale gas development have progressed rapidly in China as well. For example, the new depositional patterns have been introduced for deciphering the paleogeography and sedimentary systems of the Wufeng shale and Longmaxi shale in the Sichuan Basin. The shale gas storage mechanism has been widely accepted as differing from conventional natural gas in that it is adsorbed on organic matter or a mineral surface or occurs as free gas trapped in pores and fractures of the shale. Significant advances in the techniques of microstructural characterization have provided new insights on how gas molecules are stored in micro- and nano-scale porous shales. Furthermore, newly-developed concepts and practices in the petroleum industry, such as hydraulic fracturing, microseismic monitoring and multiwell horizontal drilling, have made the production of this unevenly distributed but promising unconventional natural gas a reality. China has 10–36 trillion m^3 of promising shale gas among the world's whole predicted technically recoverable reserves of 206.6 trillion m^3. China is on the way to achieving its goal of an annual yield of 30–50 billion m^3 by launching more trials within shale gas projects. | ZOU Caineng YANG Zhi PAN Songqi CHEN Yanyan LIN Senhu HUANG Jinliang WU Songtao DONG Dazhong WANG Shufang LIANG Feng SUN Shasha HUANG Yong WENG Dingwei | 2016 | Acta Geologica Sinica(English Edition)2016，90，4： | 9 |
| 4 | Percent free prostate-specific antigen for prostate cancer diagnosis in Chinese men with a PSA of 4.0-10.0 ng/mL:Results from the Chinese Prostate Cancer Consortium显示文摘Objective:To test the diagnostic performance of percent free prostate-specific antigen(%fPSA)in predicting any prostate cancer(PCa)and high-grade prostate cancer(HGPCa)in a retrospective multi-center biopsy cohort with a PSA level of 4.0e10.0 ng/mL in China.Methods:Consecutive patients with a PSA of 4.0-10.0 ng/mL who underwent transrectal ultrasound-guided biopsy were enrolled at 16 Chinese medical centers from January 1st,2010 to December 31st,2013.Total and free serum PSA determinations were performed using three types of electro-chemiluminescence immunoassays recalibrated to the World Health Organization(WHO)standard.The diagnostic accuracy of PSA,%fPSA,and %fPSA in combination with PSA(%fPSA t PSA)was determined using the area under the receiver operating characteristic(ROC)curve(AUC).Results:A total of 2310 consecutive men with PSA levels between 4.0 and 10.0 ng/mL were included,and the detection rate of PCa was 25.1%.The AUC of%fPSA and %fPSA t PSA in predicting any PCa was superior to PSA alone in men aged≥60 years(0.623 vs.0.534,p<0.0001)but not in men aged 40e59 years(0.517 vs.0.518,p=0.939).Similar result was yield in predicting HGPCa.Conclusion:In a clinical setting of Chinese men with 4.0e10.0 ng/mL PSA undergoing initial prostate biopsy,adding %fPSA to PSA can moderately improve the diagnostic accuracy for any PCa and HGPCa compared with PSA alone in patients≥60 but not in patients aged 40-59 years. | Rui Chen Liping Xie Xiaobing Cai Yiran Huang Liqun Zhou Lulin Ma Xu Gao Chuanliang Xu Shancheng Ren Pengfei Shao Danfeng Xu Kexin Xu Zhangqun Ye Chunxiao Liu Dingwei Ye Li Lu Qiang Fu Jianquan Hou Jianlin Yuan Dalin He Tie Zhou Fubo Wang Biming He Yinghao Sun | 2015 | Asian Journal of Urology2015，2，2： | 8 |
| 5 | Experimental push/pull production planning and control system显示文摘 | Wang Dingwei Chen Xianzhang Li Ying | 1996 | Production Planning & Control1996，7，3： | 1 |
| 6 | Race-specific genetic risk score is more accurate than nonrace-specific genetic risk score for predicting prostate cancer and high-grade diseases显示文摘基因风险分数(GRS ) 基于疾病联系风险的单个核苷酸多型性(SNP ) 是能被用来除了家庭历史为特定的疾病提供继承信息的一个增进知识的工具。然而,当计算 GRS 时,在一个特定的种族组被含有的 SNP 是否仅仅应该被使用,仍然是未知的。学习是为在 1338 个病人之中预言前列腺癌症(PCa ) 比较赛跑特定的 GRS 和 nonrace 特定的 GRS 的表演的这的目的在上海经历了前列腺活体检视,中国。赛跑特定的 GRS 与七 PCa 联系风险的 SNP 被计算在东方亚洲人(GRS7 ) 含有,并且 nonrace 特定的 GRS 基于 76 PCa 联系风险的 SNP 是计算的在至少一个种族组(GRS76 ) 含有。分别地, GRS7 和 GRS76 的工具在学习人口是 1.19 和 1.85。更高的 GRS7 和 GRS76 在 univariate 和 multivariate 分析是为 PCa 和高级 PCa 的独立预言者。GRS7 为区别 PCa (0.602 对 0.573 ) 和高级 PCa (0.603 对 0.575 ) 比 GRS76 在操作接收装置的曲线(AUC ) 下面有一个更好的区域但是没到达统计意义。有的 GRS7 一更好(多达 13% 在不同截止) 积极预兆的价值(PPV ) 比 GRS76。在结论,赛跑特定的 GRS 是更柔韧的并且当比用没被显示与东方亚洲人被联系的 SNP 计算的 GRS 在东方亚洲人预言 PCa 时,有更好的表演。 | Rong Na Dingwei Ye Jun Qi Fang Liu Xiaoling Lin Brian T Helfand Charles B Brendler Carly Conran Jian Gong Yishuo Wu Xu Gao Yaqing Chen S Lilly Zheng Zengnan Mo Qiang Ding Yinghao Sun Jianfeng Xu | 2016 | Asian Journal of Andrology2016，18，4： | 1 |
| 7 | Targeting the Neddylation Pathway to Suppress the Growth of Prostate Cancer Cells: Therapeutic Implication for the Men’s Cancer显示文摘 | Xiaofang Wang Lihui Li Yupei Liang Chunjie Li Hu Zhao Dingwei Ye Menghong Sun Lak Shin Jeong Yan Feng Shen Fu Lijun Jia Xiaomao Guo Zhen Chen | 2014 | BioMed Research International2014，，： | 1 |
| 8 | Survival after radical cystectomy for bladder cancer:Multicenter comparison between minimally invasive and open approaches显示文摘Objective:To investigate oncological outcomes in patients with bladder cancer who underwent minimally invasive radical cystectomy(MIRC)or open radical cystectomy(ORC).Methods:We identified patients with bladder cancer who underwent radical cystectomy(RC)in 13 centers of the Chinese Bladder Cancer Consortium(CBCC).Perioperative outcomes were compared between MIRC and ORC.The influence of surgical approaches on overall survival(OS)and cancer-specific survival(CSS)in the entire study group and subgroups classified according to pathologic stage or lymph node(LN)status was assessed with the log-rank test.Multivariable Cox proportional hazard models were used to evaluate the association among OS,CSS and risk factors of interest.Results:Of 2098 patients who underwent RC,1243 patients underwent MIRC(1087 laparoscopic RC and 156 robotic-assisted RC,respectively),while 855 patients underwent ORC.No significant differences were noted in positive surgical margin rate and 90-day postoperative mortality rate.MIRC was associated with less estimated blood loss,more LN yield,higher rate of neobladder diversion,longer operative time,and longer length of hospital stay.There was no significant difference in OS and CSS according to surgical approaches(pZ0.653,and 0.816,respectively).Subgroup analysis revealed that OS and CSS were not significantly different regardless of the status of extravesical involvement or LN involvement.Multivariable Cox regression analyses showed that the surgical approach was not a significant predictor of OS and CSS.Conclusions:Our study showed that MIRC was comparable to conventional ORC in terms of OS and CSS. | Weibin Xie Junming Bi Qiang Wei Ping Han Dongkui Song Lei Shi Dingwei Ye Yijun Shen Xin Gou Weiyang He Shaogang Wang Zheng Liu Jinhai Fan Kaijie Wu Zhiwen Chen Xiaozhou Zhou Chuize Kong Yang Liu Chunxiao Liu Abai Xu Baiye Jin Guanghou Fu Wei Xue Haige Chen Tiejun Pan Zhong Tu Tianxin Lin Jian Huang | 2020 | Asian Journal of Urology2020，7，3： | 1 |
| 9 | Analysis of the developmental characteristics and major regulating factors of fractures in marine–continental transitional shale-gas reservoirs: A case study of the Carboniferous–Permian strata in the southeastern Ordos Basin, central China显示文摘 | Wenlong Ding Dingwei Zhu Junjie Cai Meilin Gong Fuyan Chen | 2013 | Marine and Petroleum Geology2013，，： | 1 |
| 10 | Erratum to“Immobilized laccase on magnetic nanoparticles for enhanced lignin model compounds degradation”[Chin.J.Chem.Eng.28(8)(2020)2152-2159]显示文摘The authors regret that Fig.7b in our original article was incorrectly published,which is the same as Fig.6b due to an unintentional and random error.The correct Fig.7b is shown as follows(Reusability of the immobilized laccase).The change does not affect the results and conclusions. | Xinyan Chen Bin He Mi Feng Dingwei Zhao Jian Sun | 2020 | Chinese Journal of Chemical Engineering2020，28，12： | 1 |
| 11 | Graded Mean Integra- tion Representation of Generalized Fuzzy Number 显示文摘 | Chen S H Wang Dingwei | 1999 | Journal of Chinese Fuzzy Systems1999，5，2： | 1 |
| 12 | Immobilized laccase on magnetic nanoparticles for enhanced lignin model compounds degradation显示文摘As a natural aromatic polymer,lignin has great potential but limited industrial application due to its complex chemical structure.Among strategies for lignin conversion,biodegradation has attracted promising interest recently in term of efficiency,selectivity and mild condition.In order to overcome the issues of poor stability and non-reusability of enzyme in the biodegradation of lignin,this work explored a protocol of immobilized laccase on magnetic nanoparticles(MNPs)with rough surfaces for enhanced lignin model compounds degradation.Scanning electron microscope with energy dispersive spectrometer(SEM-EDS),flourier transformation infrared spectroscopy(FTIR)and thermal gravimetric analysis(TGA)were utilized to characterize the immobilization of laccase.The results showed a maximum activity recovery of 64.7%towards laccase when it was incubated with MNPs and glutaraldehyde(GA)with concentrations of 6 mg·ml^-1and 7.5 mg·ml^-1for 5 h,respectively.The immobilized laccase showed improved thermal stability and pH tolerance compared with free laccase,and remained more than 80%of its initial activity after 20 days of storage at 4℃.In addition,about 40%residual activity of the laccase remained after 8 times cycles.Gas chromatography–mass spectrometry(GC–MS)was utilized to characterize the products of lignin model compound degradation and activation,and the efficiency of immobilized laccase was calculated to be 1–5 times that of free laccase.It was proposed that the synergistic effect between MNPs and laccase displays an important role in the enhancement of stability and activity in lignin model compound biodegradation. | Xinyan Chen Bin He Mi Feng Dingwei Zhao Jian Sun | 2020 | Chinese Journal of Chemical Engineering2020，28，8： | 1 |
| 13 | MEMS and MOEMS Gyroscopes: A Review显示文摘Micro-gyroscopes using micro-electro-mechanical system(MEMS)and micro-optoelectro-mechanical system(MOEMS)are the new-generation and recently well-developed gyroscopes produced by the combinations of the traditional gyroscope technology and MEMS/MOEMS technologies.According to the working principle and used materials,the newly-reported micro-gyroscopes in recent years include the silicon-based micromechanical vibratory gyroscope,hemispherical resonant gyroscope,piezoelectric vibratory gyroscope,suspended rotor gyroscope,microfluidic gyroscope,optical gyroscope,and atomic gyroscope.According to different sensitive structures,the silicon-based micromechanical vibratory gyroscope can also be divided into double frame type,tuning fork type,vibrating ring type,and nested ring type.For those micro-gyroscopes,in recent years,many emerging techniques are proposed and developed to enhance different aspects of performances,such as the sensitivity,angle random walk(ARW),bias instability(BI),and bandwidth.Therefore,this paper will firstly review the main performances and applications of those newly-developed MEMS/MOEMS gyroscopes,then comprehensively summarize and analyze the latest research progress of the micro-gyroscopes mentioned above,and finally discuss the future development trends of MEMS/MOEMS gyroscopes. | Wenyi HUANG Xing YAN Sengyu ZHANG Zhe LI Jamal NAHASSAN Dingwei CHEN Guangjun WEN Kai CHEN Guangwei DENG Yongjun HUANG | 2023 | Photonic Sensors2023，13，4： | 0 |
| 14 | Analysis of Buddhist sculpture art in Wei, Jin, southern and Northern Dynasties显示文摘 | ZHANG Dingwei CHEN Liesheng | 2017 | International English Education Research2017，，2： | 0 |
| 15 | THE THERMAL EFFECT OF FERRIMAGNETIC RESONANCE AND ITS PROBABLE APPLICATION IN MICROWAVE HYPERTHERMIA IN CANCER THERAPY显示文摘To improve microwave hyperthevmia in cancer therapy, the thermal effect of fer-rimagnetic resonance (FMR) during microwave irradiation was studied. Resonant temperatureelevation (RTE) of single crystal grain and polycrystal powder of resonant media was measuredalone and in imitative muscle and egg white and in mice. The results indicated that the RTE produced by FMR could be used to improve penetrationdeepness, heating selectivity and temperature distribution of microwave hyperthermia in cancertreatment. It was expected that the potential function of the FMR heating system would be ex-ploited greatly for cancer therapy, and then magnetically guided microwave hyperthermia thera-py, chemotherapy, radiotherapy and immunotherapy might he combined multiply within this sys-tem by means of the static magnetic field (SMF) and magnetic microcarrier. Limitation of reso-nant heating was also discussed in this paper. | Chen Guozhang, Wu Ganghua,Dong Dingwei Zhejiang Medical University Zhejiang Institute of Techonology | 1993 | Chinese Journal of Biomedical Engineering(English Edition)1993，2，1： | 0 |
| 16 | 全基因组关联研究发现中国人群前列腺癌两个新易感位点9q31.2和19q13.4显示文摘0前言在全球范围内,前列腺癌的发病率和病死率存在着巨大差异。该病在西方发达国家发病率最高,在非裔美国人群病死率最高,而在亚洲人群中发病率及病死率均为全球最低,提示不同人种在前列腺癌的遗传方面存在异质性。在欧美和日本人群中,全基因组关联研究(GWAS)技术已经被用于检测前列腺癌的遗传易感性位点,但至今尚无关于GWAS检测中国人群前列腺癌易感位点的报道。 | Jianfeng Xu Zengnan Mo Dingwei Ye Meilin Wang Fang Liu Guangfu Jin Chuanliang Xu Xiang Wang Qiang Shao Zhiwen Chen Zhihua Tao Jun Qi Fangjian Zhou Zhong Wang Yaowen Fu Dalin He Qiang Wei Jianming Guo Denglong Wu Xin Gao Jianlin Yuan Gongxian Wang Yong Xu Guozeng Wang Haijun Yao Pei Dong Yang Jiao Mo Shen Jin Yang Jun Ou-Yang Haowen Jiang Yao Zhu Shancheng Ren Zhengdong Zhang Changjun Yin Xu Gao Bo Dai Zhibin Hu Yajun Yang Qijun Wu Hongyan Chen Peng Peng Ying Zheng Xiaodong Zheng Yongbing Xiang Jirong Long Jian Gong Rong Na Xiaoling Lin Hongjie Yu Sha Tao Junjie Feng Jishan Sun Wennuan Liu Ann Hsing Jianyu Rao Qiang Ding Fredirik Wiklund Henrik Gronberg Xiao-Ou Shu Wei Zheng Hongbing Shen Li Jin Rong Shi Daru Lu Xuejun Zhang Jielin Sun S Lilly Zheng Yinghao Sun | 2013 | 第二军医大学学报2013，34，4： | 0 |
| 17 | Real-world effectiveness and safety of goserelin 10.8-mg depot in Chinese patients with localized or locally advanced prostate cancer显示文摘Objective:Real-word data on long-acting luteinizing hormone-releasing hormone(LHRH)agonists in Chinese patients with prostate cancer are limited.This study aimed to determine the real-world effectiveness and safety of the LHRH agonist,goserelin,particularly the long-acting 10.8-mg depot formulation,and the follow-up patterns among Chinese prostate cancer patients.Methods:This was a multicenter,prospective,observational study in hormone treatment-na?ve patients with localized or locally advanced prostate cancer who were prescribed goserelin 10.8-mg depot every 12 weeks or 3.6-mg depot every 4 weeks with or without an anti-androgen.The patients had follow-up evaluations for 26 weeks.The primary outcome was the effectiveness of goserelin in reducing serum testosterone and prostate-specific antigen(PSA)levels.The secondary outcomes included testosterone and PSA levels,attainment of chemical castration(serum testosterone<50 ng/d L),and goserelin safety.The exploratory outcome was the monitoring pattern for serum testosterone and PSA.All analyses were descriptive.Results:Between September 2017 and December 2019,a total of 294 eligible patients received≥1 dose of goserelin;287 patients(97.6%)were treated with goserelin 10.8-mg depot.At week 24±2,the changes from baseline[standard deviation(95%confidence interval)]in serum testosterone(n=99)and PSA(n=131)were-401.0 ng/d L[308.4 ng/d L(-462.5,-339.5 ng/d L)]and-35.4 ng/m L[104.4 ng/m L(-53.5,-17.4 ng/m L)],respectively.Of 112 evaluable patients,100(90.2%)achieved a serum testosterone level<50 ng/d L.Treatment-emergent adverse events(TEAEs)and severe TEAEs occurred in 37.1%and 10.2%of patients,respectively.The mean testing frequency(standard deviation)was 1.6(1.5)for testosterone and 2.2(1.6)for PSA.Conclusions:Goserelin 10.8-mg depot effectively achieved and maintained castration and was well-tolerated in Chinese patients with localized and locally advanced prostate cancer. | Nanhui Chen Zengjun Wang Ming Chen Qi Ma Yi He Yujie Wang Xin Li Mingxing Qiu Lei Shi Shaoxing Zhu Qun Xie Xiuheng Liu Benkang Shi Guowen Lin Weizhong Yang Yongbin Liao Haibin Zhang Shusheng Wang Jiexian Li Shaogang Wang Lijun Dong Hui Chen Jiaju Lu YongyiCheng Xiaoping Zhang Lulin Ma Liqun Zhou He Wang Shen Li Dingwei Ye | 2023 | Cancer Biology & Medicine2023，20，12： | 0 |
| 18 | Proppant transport law in multi-branched fractures induced by volume fracturing显示文摘To further clarify the proppant transport and placement law in multi-branched fractures induced by volume fracturing, proppant transport simulation experiments were performed with different fracture shapes, sand ratios, branched fracture opening time and injection sequence of proppants in varied particle sizes. The results show that the settled proppant height increases and the placement length decreases in main fractures as the fracturing fluid diverts gradually to the branched fractures at different positions. The flow rate in branched fractures is the main factor affecting their filling. The diverion to branched fractures leads to low flow rate and poor filling of far-wellbore branched fractures. The inclined fracture wall exerts a frictional force on the proppant to slow its settlement, thus enhancing the vertical proppant distribution in the fracture. The increase of sand ratio can improve the filling of near-wellbore main fracture and far-wellbore branched fracture and also increase the settled proppant height in main fracture. Due to the limitation of fracture height, when the sand ratio increases to a certain level, the increment of fracture filling decreases. When branched fracture is always open(or extends continuously), the supporting effect on the branched fractures is the best, but the proppant placement length within the main fractures is shorter. The fractures support effect is better when it is first closed and then opened(or extends in late stage) than when it is first opened and then closed(or extends in early stage). Injecting proppants with different particle sizes in a specific sequence can improve the placement lengths of main fracture and branched fracture. Injection of proppants in an ascending order of particle size improves the near-wellbore fracture filling, to a better extent than that in a descending order of particle size. | GUO Tiankui LYU Mingkun CHEN Ming XU Yun WENG Dingwei QU Zhanqing DAI Caili HOU Jian LIU Xiaoqiang | 2023 | Petroleum Exploration and Development2023，50，4： | 0 |
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