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| 1 | Receptor-interacting protein (RIP) kinase family显示文摘Receptor-interacting protein(RIP)kinases are a group of threonine/serine protein kinases with a relatively conserved kinase domain but distinct non-kinase regions.A number of different domain structures,such as death and caspase activation and recruitment domain(CARD)domains,were found in different RIP family members,and these domains should be keys in determining the specific function of each RIP kinase.It is known that RIP kinases participate in different biological processes,including those in innate immunity,but their downstream substrates are largely unknown.This review will give an overview of the structures and functions of RIP family members,and an update of recent progress in RIP kinase research. | Duanwu Zhang Juan Lin Jiahuai Han | 2010 | Cellular & Molecular Immunology2010，7，4： | 23 |
| 2 | Emerging roles of spliceosome in cancer and immunity显示文摘Precursor messenger RNA(pre-mRNA)splicing is cat-alyzed by an intricate ribonucleoprotein complex called the spliceosome.Although the spliceosome is consid-ered to be general cell'housekeeping'machinery,mutations in core components of the spliceosome fre-quently correlate with cell-or tissue-specific pheno-types and diseases.In this review,we expound the links between spliceosome mutations,aberrant splicing,and human cancers.Remarkably,spliceosome-targeted therapios(STTs)have become efficient anti-cancer strategies for cancer patients with splicing defects.We also highlight the links between spliceosome and immune signaling.Recent studies have shown that some spliceosome gene mutations can result in immune dysregulation and notable phenotypes due to mis-splicing of immune-related genes.Furthermore,several core spliceosome components harbor splicing-inde-pendent immune functions within the cell,expanding the functional repertoire of these diverse proteins. | Hui Yang Bruce Beutler Duanwu Zhang | 2022 | Protein & Cell2022，13，8： | 1 |
| 3 | Effects of Bio-organic Selenium on Agronomic Economic Traits and Selenium Absorption and Distribution in Rice显示文摘Under the same conditions of selenium application and application period,different application concentration treatments were set carry out the field plot experiments. The results showed that different treatments had no effect on the growth and development of rice plants;different treatments had an effect on the economic traits of rice; selenium treatment increased the number of filled grains per panicle,seed setting rate and 1 000-grain weight,thus increasing yield; the level of yield was Se4 > Se3 > Se2 > Se1 > Se0; different treatments had a greater effect on the milled rice rate; selenium treatment increased the milled rice rate; the milled rice rate of Se3 and Se4 treatments were 65% and 64%,respectively,which was significantly higher than that of the control group; the general law of selenium absorption of rice was leaf > stem> rice; the selenium content in leaves,stems and rice of different treatments was the highest in Se3 treatment; both the selenium content of rice( total selenium and organic selenium) and the ratio of organic selenium to total selenium in the selenium treatment met the local food safety standard of Hubei Province Selenium content of Selenium-enriched Foods( DBS42/002-2014); selenium-treated rice plants had a high selenium utilization rate,in the range of 51. 26%-64. 12%,exceeding 50%. | Xiaoling LONG Duanwu CAI Jinlong LIU Wei ZHENG | 2018 | Asian Agricultural Research2018，10，12： | 1 |
| 4 | A Role of RIP3-Mediated Macrophage Necrosis in Atherosclerosis Development显示文摘 | Juan Lin Hanjie Li Min Yang Junming Ren Zhe Huang Felicia Han Jian Huang Jianhui Ma Duanwu Zhang Zhirong Zhang Jianfeng Wu Deli Huang Muzhen Qiao Guanghui Jin Qiao Wu Yinghui Huang Jie Du Jiahuai Han | 2013 | Cell Reports2013，，1： | 1 |
| 5 | Ontology- based similarity measure for text clustering 显示文摘 | Yan Duanwu Li Xiaopeng Wang L e I Cheng X iao | 2006 | Journal of Southeast University2006，22，3： | 1 |
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