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| 1 | Inhibition of angiogenesis and HCT-116 xenograft tumor growth in mice by kallistatin显示文摘AIM: To investigate the inhibitory effect of kallistatin (KAL) on angiogenesis and HCT-116 xenograft tumor growth. METHODS: Heterotopic tumors were induced by subcutaneous injection of 2 × 106 HCT-11 cells in mice. Seven days later, 2 × 1011 rAAV-GFP or rAAV-KAL was injected intratumorally (n = 5 for each group). The mice were sacrificed at d 28, by which time the tumors in the rAAV-GFP group had grown to beyond 5% of the total body weight. Tumor growth was measured by calipers in two dimensions. Tumor angiogenesis was determined with tumor microvessel density (MVD) by immunohistology. Tumor cell proliferation was assessed by Ki-67 staining. RESULTS: Intratumor injection of rAAV-KAL inhibited tumor growth in the treatment group by 78% (171 ± 52 mm3) at d 21 after virus infection compared to the control group (776 ± 241 mm3). Microvessel density was significantly inhibited in tumor tissues treated with rAAV-KAL. rAAV-KAL also decreased the proportion of proliferating cells (Ki-67 positive cells) in tumors compared with the control group.CONCLUSION: rAAV-mediated expression of KAL inhibits the growth of colon cancer by reducing angiogenesis and proliferation of tumor cells, and may provide a promising anti-angiogenesis-based approach to the treatment of metastatic colorectal cancer. | Yong Diao Jian Ma Wei-Dong Xiao Jia Luo Xin-Yan Li Kin-Wah Chu Peter WC Fung Nagy Habib Farzin Farzaneh Rui-An Xu | 2007 | World Journal of Gastroenterology2007，13，34： | 15 |
| 2 | Acute ankle sprain in athletes:Clinical aspects and algorithmic approach显示文摘Acute ankle sprain is the most common lower limb injury in athletes and accounts for 16%-40%of all sports-related injuries.It is especially common in basketball,American football,and soccer.The majority of sprains affect the lateral ligaments,particularly the anterior talofibular ligament.Despite its high prevalence,a high proportion of patients experience persistent residual symptoms and injury recurrence.A detailed history and proper physical examination are diagnostic cornerstones.Imaging is not indicated for the majority of ankle sprain cases and should be requested according to the Ottawa ankle rules.Several interventions have been recommended in the management of acute ankle sprains including rest,ice,compression,and elevation,analgesic and anti-inflammatory medications,bracing and immobilization,early weight-bearing and walking aids,foot orthoses,manual therapy,exercise therapy,electrophysical modalities and surgery(only in selected refractory cases).Among these interventions,exercise and bracing have been recommended with a higher level of evidence and should be incorporated in the rehabilitation process.An exercise program should be comprehensive and progressive including the range of motion,stretching,strengthening,neuromuscular,proprioceptive,and sport-specific exercises.Decision-making regarding return to the sport in athletes may be challenging and a sports physician should determine this based on the self-reported variables,manual tests for stability,and functional performance testing.There are some common myths and mistakes in the management of ankle sprains,which all clinicians should be aware of and avoid.These include excessive imaging,unwarranted non-weightbearing,unjustified immobilization,delay in functional movements,and inadequate rehabilitation.The application of an evidence-based algorithmic approach considering the individual characteristics is helpful and should be recommended. | Farzin Halabchi Mohammad Hassabi | 2020 | World Journal of Orthopedics2020，11，12： | 14 |
| 3 | 压水堆一回路主管道316L不锈钢的电化学腐蚀行为显示文摘通过中心复合设计试验法设计试验,结合动电位极化曲线和电化学阻抗谱的测量以及氧化膜形貌观察和成分测量,研究了温度(30~350℃)、Cl^-质量浓度(10~1000μg·L-1)和溶解氧质量浓度(0~200μg·L-1)3种因素对压水堆一回路主管道316L不锈钢电化学腐蚀性能的影响.结果表明:温度是影响316L不锈钢电化学腐蚀性能最显著的因素,温度越高,腐蚀电流密度越大,点蚀电位越低;Cl^-浓度和溶解氧浓度对316L不锈钢电化学腐蚀性能的影响与温度密切相关,温度较低时(T<150℃),Cl^-浓度和溶解氧浓度均对316L腐蚀电流密度几乎无影响,但点蚀电位却随Cl^-浓度增加和溶解氧浓度的降低而降低;温度较高时,分别为T>130℃和T>150℃,Cl^-浓度和溶解氧浓度均对316L点蚀电位几乎无影响,但腐蚀电流密度却随Cl^-和溶解氧的浓度增加而显著增加,腐蚀加剧.电化学阻抗谱的测量和氧化膜形貌的观察也进一步验证了上述试验结果. | 汪家梅 Farzin Arjmand 杜东海 陈凯 赖平 高文华 张浩 郭相龙 张乐福 | 2017 | 工程科学学报2017，39，9： | 10 |
| 4 | Effects of rainfall patterns on runoff and rainfall-induced erosion显示文摘Rainfall-induced erosion involves the detachment of soil particles by raindrop impact and their transport by the combined action of the shallow surface runoff and raindrop impact.Although temporal variation in rainfall intensity(pattern)during natural rainstorms is a common phenomenon,the available information is inadequate to understand its effects on runoff and rainfall-induced erosion processes.To address this issue,four simulated rainfall patterns(constant,increasing,decreasing,and increasing-decreasing)with the same total kinetic energy were designed.Two soil types(sandy and sandy loam)were subjected to simulated rainfall using 15 cm×30 cm long detachment trays under infiltration conditions.For each simulation,runoff and sediment concentration were sampled at regular intervals.No obvious difference was observed in runoff across the two soil types,but there were significant differences in soil losses among the different rainfall patterns and stages.For varying-intensity rainfall patterns,the dominant sediment transport mechanism was not only influenced by raindrop detachment but also was affected by raindrop-induced shallow flow transport.Moreover,the efficiency of equations that predict the interrill erosion rate increased when the integrated raindrop impact and surface runoff rate were applied.Although the processes of interrill erosion are complex,the findings in this study may provide useful insight for developing models that predict the effects of rainfall pattern on runoff and erosion. | Morteza Alavinia Farzin Nasiri Saleh Hossain Asadi | 2019 | International Journal of Sediment Research2019，34，3： | 9 |
| 5 | Development of minimally invasive techniques for management of medically-complicated obesity显示文摘The field of bariatric surgery has been rapidly growing and evolving over the past several decades. During the period that obesity has become a worldwide epidemic, new interventions have been developed to combat this complex disorder. The development of new laparoscopic and minimally invasive treatments for medically-complicated obesity has made it essential that gastrointestinal physicians obtain a thorough understanding of past developments and possible future directions in bariatrics. New laparoscopic advancements provide patients and practitioners with a variety of options that have an improved safety profile and better efficacy without open, invasive surgery. The mechanisms of weight loss after bariatric surgery are complex and may in part be related to altered release of regulatory peptide hormones from the gut. Endoscopic techniques designed to mimic the effects of bariatric surgery and endolumenal inter-ventions performed entirely through the gastrointestinal tract offer potential advantages. Several of these new techniques have demonstrated promising, preliminary results. We outline herein historical and current trends in the development of bariatric surgery and its transition to safer and more minimally invasive procedures designed to induce weight loss. | Farzin Rashti Ekta Gupta Suzan Ebrahimi Timothy R Shope Timothy R Koch Christopher J Gostout | 2014 | World Journal of Gastroenterology2014，20，37： | 4 |
| 6 | A simplified method for collapse capacity assessment of moment-resisting frame and shear wall structural systems显示文摘 | Behrouz Shafei Farzin Zareian Dimitrios G. Lignos | 2010 | Engineering Structures2010，，4： | 3 |
| 7 | NUMERICAL PREDICTIONS AND EXPERIMENTAL VALIDATIONS OF DUCTILE DAMAGE EVOLUTION IN SHEET METAL FORMING PROCESSES显示文摘Prediction of forming limit in sheet metal forming is among the most important challenges confronting researchers. In this paper, a fully coupled elastic-plastic-damage model has been developed and implemented into an explicit code. Due to the adoption of the plane stress and finite strain theories, model can predict deformation and damage of parts quickly and accurately. Also, damage initiation, propagation, and fracture in some operations are predicted and validated with experiments. It is concluded that finite strain combined with continuum damage mechanics can be used as a quick tool to predict ductile damage, fracture, and forming limits in sheet metal forming processes. | Farhad Haji Aboutalebi Mahmoud Farzin Mohammad Mashayekhi | 2012 | Acta Mechanica Solida Sinica2012，25，6： | 3 |
| 8 | Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study显示文摘 | Jean-Philippe Collet Jean-Sébastien Hulot Anna Pena Eric Villard Jean-Baptiste Esteve Johanne Silvain Laurent Payot Delphine Brugier Guillaume Cayla Farzin Beygui Gilbert Bensimon Christian Funck-Brentano Gilles Montalescot | 2009 | The Lancet . 2009 (9660)2009，，： | 2 |
| 9 | Eliciting cytotoxic T lymphocytes against acute myeloid leukemia-derived antigens: evaluation of dendritic cell–leukemia cell hybrids and other antigen-loading strategies for dendritic cell-based vaccination显示文摘 | Joanna Galea-Lauri David Darling Ghulam Mufti Phillip Harrison Farzin Farzaneh | 2002 | Cancer Immunology, Immunotherapy2002，，6： | 2 |
| 10 | Facies Analysis and Sequence Stratigraphy of Silurian Carbonate Ramps in the Turan(Kopeh-Dagh) and Central Iran Plates with Emphasis on Gondwana Tectonic Event显示文摘Two sections from the Silurian deposits in the Central Iran Micro and Turan Plates were measured and sampled. These deposits are mostly composed of submarine volcanic rocks, skeletal and non-skeletal limestone, shale and sandstone that were deposited in low to high energy conditions(from tidal flat to deep open marine). According to gradual deepening trend, wide lateral distribution of facies as well as absence of resedimentation deposits, a depositional model of a homoclinal ramp was proposed for these deposits. Field observations and facies distribution indicate that, two depositional sequences were recognized in both sections. These sections show similarities in facies and depositional sequence during the Early Silurian in the area. Although there are some opinions and evidences that demonstrated Paleo-Tethys rifting phase started at the Late Ordovician-Early Silurian, similarities suggest that the Turan and Iran Plates were not completely detached tectonic block during this time, and that their depositional conditions were affected by global sea level changes and tectonic events. | Zohreh NOWROUZI Asadollah MAHBOUBI Reza MOUSSAVI-HARAMI Mohammad Hossein MAHMUDY GHARAIE Farzin GHAEMI | 2015 | Acta Geologica Sinica(English Edition)2015，89，4： | 2 |
| 11 | Nonpoint souree pollution control under incomplete and costly information 显示文摘 | Farzin Y H Kaplan J D | 2004 | Environmental and Resource Economics2004，28，： | 1 |
| 12 | Determination of buckling limit of strain in cold forming by the finite element analysis 显示文摘 | Farzin M Salmani Tehrani M Shameli E | 2002 | Journal of Materials Processing Technology2002，，： | 1 |
| 13 | Optimal timing of technology adoption 显示文摘 | Farzin Y H Huisman KJ M | 1998 | Journal of Economic Dynamics and Control1998，22，5： | 1 |
| 14 | Effect of Surface Treatment on Diffusion and Domain Formation in Supported Lipid Bilayers显示文摘 | Kalani J. Seu Anjan P. Pandey Farzin Haque Elizabeth A. Proctor Alexander E. Ribbe Jennifer S. Hovis | 2007 | Biophysical Journal2007，，7： | 1 |
| 15 | Fuzzy Adaptive Modified PSO-Algorithm Assisted to Design of Photonic Crystal Fiber Raman Amplifier 显示文摘 | Majid Akhlaghi Farzin Emami | 2013 | Journal of the Optical Society of Korea2013，17，3： | 1 |
| 16 | Remifentanil Added to Propofol for Induction of Anesthesia Can Reduce Reorientation Time After Electroconvulsive Therapy in Patients With Severe Mania显示文摘 | Farzin Rezaei Karim Nasseri Gholam Reza Esfandiari Sayed Mohammad Hossein Sadeghi Mohammad Fathie Fardin Gharibi | 2012 | The Journal of Electroconvulsive Therapy2012，，2： | 1 |
| 17 | Fluore- containing Poly (amide-imide) s with Sterically Hindered Pendants: Synthesis and Characterization 显示文摘 | Hossein Behniafar Farzin Zardoozi Ali Rastkar | 2012 | Journal of Fluorine Chemistry2012，138，： | 1 |
| 18 | A high sensitive electro- chemical aptasensor for the determination of VEGFl 65 in serum of lung cancer patient显示文摘 | Amouzadeh TM Shamsipur M Farzin L | 2015 | Biosens Bioelectron2015，74，： | 1 |
| 19 | Analysis of blanking process using various damage criteria显示文摘 | Farzin M Javani H R Mashayekhi M | 2006 | Journal of Materials Processing Technology2006，177，13： | 1 |
| 20 | Analysis of blanking process using various damage criteria 显示文摘 | FARZIN M JAVANI H R MASHAYEKHI M | 2006 | Journal of Materials Processing Technology2006，177，： | 1 |
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