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| 1 | Geochemical Characteristics and Genetic Types of Natural Gas in the Xinchang Gas Field, Sichuan Basin, SW China显示文摘The molecular compositions and stable carbon and hydrogen isotopic compositions of natural gas from the Xinchang gas field in the Sichuan Basin were investigated to determine the genetic types. The natural gas is mainly composed of methane (88.99%–98.01%), and the dryness coefficient varies between 0.908 and 0.997. The gas generally displays positive alkane carbon and hydrogen isotopic series. The geochemical characteristics and gas-source correlation indicate that the gases stored in the 5^(th) member of the Upper Triassic Xujiahe Formation are coal-type gases which are derived from source rocks in the stratum itself. The gases reservoired in the 4^(th) member of the Xujiahe Formation and Jurassic strata in the Xinchang gas field are also coal-type gases that are derived from source rocks in the 3^(rd) and 4^(th) members of the Xujiahe Formation. The gases reservoired in the 2^(nd) member of the Upper Triassic Xujiahe Formation are mainly coal-type gases with small amounts of oil-type gas that is derived from source rocks in the stratum itself. This is accompanied by a small amount of contribution brought by source rocks in the Upper Triassic Ma'antang and Xiaotangzi formations. The gases reservoired in the 4^(th) member of the Middle Triassic Leikoupo Formation are oil-type gases and are believed to be derived from the secondary cracking of oil which is most likely to be generated from the Upper Permian source rocks. | WU Xiaoqi LIU Quanyou LIU Guangxiang WANG Ping LI Huaji MENG Qingqiang CHEN Yingbin ZENG Huasheng | 2017 | Acta Geologica Sinica(English Edition)2017，91，6： | 9 |
| 2 | Differential Characteristics of the Upper Ordovician-Lower Silurian Wufeng-Longmaxi Shale Reservoir and its Implications for Exploration and Development of Shale Gas in/around the Sichuan Basin显示文摘The Upper Ordovician Wufeng-Lower Silurian Longmaxi shale is widely distributed in the Sichuan Basin and its periphery,which is the key stratum for marine shale gas exploration and development(E&D)in China.Based on sedimentary environment,material basis,storage space,fracability and reservoir evolution data,the reservoir characteristics of the Wufeng-Longmaxi shale and their significance for shale gas E&D are systematically compared and analyzed in this paper.The results show that(1)the depocenter of the Wufeng(WF)-Longmaxi(LM)shale gradually migrates from east to west.The high-quality shale reservoirs in the eastern Sichuan Basin are mainly siliceous shales,which are primarily distributed in the graptolite shale interval of WF2-LM5.The high-quality reservoirs in the southern Sichuan Basin are mainly calcareous-siliceous and organic-rich argillaceous shales,which are distributed in the graptolite shale interval of WF2-LM7.(2)Deep shale gas(the burial depth>3500 m)in the Sichuan Basin has high-ultrahigh pressure and superior physical properties.The organic-rich siliceous,calcareous-siliceous and organic-rich argillaceous shales have suitable reservoir properties.The marginal area of the Sichuan Basin has a higher degree of pressure relief,which leads to the argillaceous and silty shales evolving into direct cap rocks with poor reservoir/good sealing capacity.(3)Combining shale gas exploration practices and impacts of lithofacies,depth,pressure coefficient and brittle-ductile transition on the reservoir properties,it is concluded that the favorable depth interval of the Wufeng-Longmaxi shale gas is 2200~4000 m under current technical conditions.(4)Aiming at the differential reservoir properties of the Wufeng-Longmaxi shale in the Sichuan Basin and its periphery,several suggestions for future research directions and E&D of shale gas are formulated. | WANG Ruyue HU Zongquan LONG Shengxiang LIU Guangxiang ZHAO Jianhua DONG Li DU Wei WANG Pengwei YIN Shuai | 2019 | Acta Geologica Sinica(English Edition)2019，93，3： | 8 |
| 3 | Machine Learning−based Weather Support for the 2022 Winter Olympics显示文摘1.A key support for the 2022 Winter Olympics The XXIV Olympic Winter Games are scheduled to take place from 4 to 22 February 2022,followed by the Paralympic Games from 4 to 13 March,in Beijing and towns in the neighboring Hebei Province,China.Weather plays an extremely important role in the outcome of the games(Chen et al.,2018).It can not only cause a difference between a medal or not,but affect the safety of athletes.Success of the Winter Olympics will greatly depend on weather conditions at the outdoor competition venues,dealing with many weather elements including the snow surface temperature,apparent temperature,gust wind speed,snow,visibility,etc.To ensure that the scheduled games go smoothly,it is imperative to have hourly or even every 10-minutely forecasts as well as updated weather-related risk assessments at the venues for the next 240 hours.So far,the Beijing/Hebei Meteorological Observatory has already started intelligent weather forecasting at 3-km resolution based on the results of numerical weather prediction(NWP)models.However,these experiments have suggested that the current forecasting techniques are incapable of capturing the complex mountain weather variations around some venues.The forecasting capability of NWP is constrained partly by limited knowledge of the local weather mechanisms. | Jiangjiang XIA Haochen LI Yanyan KANG Chen YU Lei JI Lve WU Xiao LOU Guangxiang ZHU Zaiwen Wang Zhongwei YAN Lizhi WANG Jiang ZHU Pingwen ZHANG Min CHEN Yingxin ZHANG Lihao GAO Jiarui HAN | 2020 | Advances in Atmospheric Sciences2020，37，9： | 6 |
| 4 | CFD simulation of gas–liquid flow in a high-pressure bubble column with a modified population balance model显示文摘In this study,based on the Luo bubble coalescence model,a model correction factor C_e for pressures according to the literature experimental results was introduced in the bubble coalescence efficiency term.Then,a coupled modified population balance model(PBM) with computational fluid dynamics(CFD) was used to simulate a high-pressure bubble column.The simulation results with and without C_e were compared with the experimental data.The modified CFD-PBM coupled model was used to investigate its applicability to broader experimental conditions.These results showed that the modified CFD-PBM coupled model can predict the hydrodynamic behaviors under various operating conditions. | Bo Zhang Lingtong Kong Haibo Jin Guangxiang He Suohe Yang Xiaoyan Guo | 2018 | Chinese Journal of Chemical Engineering2018，26，6： | 5 |
| 5 | Two novel interpenetrated zinc(Ⅱ) and cadmium(Ⅱ) coordination polymers based on 4-imidazole-benzoate:Syntheses,crystal structures and properties显示文摘Two novel interpenetrated coordination polymers,[Zn(IBA)2]n (1) and {[Cd(IBA)2(H2O)].4H2O}n (2),have been synthesized by using 4-imidazole-benzoic acid (HIBA) as ligand under hydrothermal con-ditions. Complex 1 crystallizes in a chiral space group and has a two-fold interpenetrated 2D network structure with (4,4) topology,while complex 2 is a 3D porous dia network with four nets interpene-trating each other. The SHG activity of 1 and the photoluminescent property of 2 have been investi-gated. | BAI ZhengShuai,CHEN ShuiSheng,ZHANG ZhengHua,CHEN ManSheng,LIU GuangXiang & SUN WeiYin State Key Laboratory of Coordination Chemistry,Institute of Coordination Chemistry,School of Chemistry and Chemical Engineering,Nanjing University,Nanjing 210093,China | 2009 | Science China Chemistry2009，52，4： | 5 |
| 6 | Hepatitis C Virus Attachment Mediated by Apolipoprotein E Binding to Cell Surface Heparan Sulfate显示文摘 | Jieyun Jiang Wei Cun Xianfang Wu Qing Shi Hengli Tang Guangxiang Luo | 2012 | Journal of Virology2012，，13： | 4 |
| 7 | Recovery of infectious foot-and-mouth disease virus from full-length genomic cDNA clones using an RNA polymerase I system显示文摘prototypic foot-and-mouth 疾病病毒(FMDV ) 超过一个世纪以前被显示出是能够引起 FMD 的第一个可滤过的代理人,并且它为学习 Aphthovirus 分子的生物学的基本原则担任了一个重要模型。然而,复杂结构和 FMDV 的 antigenic 差异在由反向的基因技术操作传染病毒形成了一个主要障碍到尝试。这里,我们从 cDNAs 报导传染 FMDV 的恢复基于一在 vivo RNA 有效聚合酶吗?(pol ?) 抄写系统。从 pol 的全身的病毒的染色体的细胞内部的抄写 ? 基于的向量导致了传染病毒显示的有效形成一个基因标记。与野类型的病毒相比,许多 genomic mRNA 和病毒的抗原的提高的表示层次在整个在抄写,复制,和翻译层次的这个导出 cDNA 的病毒的生命周期的功能亢进是指示的。这里描述的技术能是为学习 FMDV 复杂传染特征的一个极其珍贵的分子的生物学工具。它是为学习 FMDV 功能的 genomics 的一个操作平台,致病力和变化的分子的机制,并且向一支遗传上设计的疫苗的前景为病毒的怪物的开发打一个稳固的基础。 | Yanyan Chang Haixue Zheng Youjun Shang Ye Jin Guangxiang Wang Xiaoyan Shen Xiangtao Liu | 2009 | Acta Biochimica et Biophysica Sinica2009，41，12： | 3 |
| 8 | The effect of operating conditions on acylation of 2-methylnaphthalene in a microchannel reactor显示文摘Acylation of 2-methylnaphthalene(2-MN) is a very important reaction in organic synthesis,and the effiency of the continuous reactor is more than one of the batch reactor.Considering that the Friedel–Crafts acylation is a rapid exothermic reaction,in this study,we perform the acylation of 2-MN in a stainless steel microchannel flow reactor,which is characterized by high mass and heat transfer rates.The effect of reactant ratio,mixing temperature,reaction temperature,and reaction time on product yield and selectivity were investigated.Under the optimal conditions,2-methyl-6-propionylnaphthalene(2,6-MPN) was obtained in 85.8% yield with 87.5% selectivity.Compared with the conventional batch system,the continuous flow microchannel reactor provides a more efficient method for the synthesis of 2,6-MPN. | Wenpeng Li Suohe Yang Xiaoyan Guo Guangxiang He Haibo Jin | 2018 | Chinese Journal of Chemical Engineering2018，26，6： | 3 |
| 9 | Expression and responses to dehydration and salinity stresses of V-PPase gene members in wheat显示文摘Vacuolar H+-translocating pyrophosphatase(V-PPase) is a key enzyme related to plant growth as well as abiotic stress tolerance.In this work,wheat V-PPase genes TaVP1,TaVP2 and TaVP3 were identified.TaVP1 and TaVP2 are more similar to each other than to TaVP3.Their deduced polypeptide sequences preserve the topological structure and essential residues of V-PPases.Phylogenetic studies suggested that monocot plants,at least monocot grasses,have three VP paralogs.TaVP3 transcripts were only detected in developing seeds,and no TaVP2 transcripts were found in germinating seeds.TaVP2 was mainly expressed in shoot tissues and down-regulated in leaves under dehydration.Its expression was up-regulated in roots under high salinity.TaVP1 was relatively more ubiquitously and evenly expressed than TaVP2.Its expression level in roots was highest among the tissues examined,and was inducible by salinity stress.These results indicated that the V-PPase gene paralogs in wheat are differentially regulated spatially and in response to dehydration and salinity stresses. | Yuezhi Wang Haibin Xu Guangxiang Zhang Huilan Zhu Lixia Zhang Zhengzhi Zhang Caiqin Zhang Zhengqiang Ma | 2009 | Journal of Genetics and Genomics2009，36，12： | 3 |
| 10 | Characteristics of sedimentation and channel adjustment linked to the Three Gorges Reservoir显示文摘Construction of large dams is attractive because of their great benefits in flood control,hydropower generation,water resources utilization,navigation improvement,etc.However,dam construction may bring some negative impacts on sediment transport and channel dynamics adjustments.Due to the effects of recent water and soil conservation projects,sediment retention in the newly constructed large upstream reservoirs,and other factors,the sedimentation in the Three Gorges Reservoir(TGR)is quite different from the amount previously predicted in the demonstration stage.Consequently,based on the measured data,characteristics of sedimentation and the related channel deformation in the TGR were analyzed.The results imply that sediment transport tended to be reduced after the Three Gorges Project(TGP).Sedimentation slowed dramatically after 2013 and indicated obvious seasonal characteristics.Due to the rising water level in the TGR in the flood season,the yearly sediment export ratio(Eratio)was prone to decrease.The water level near the dam site should be reasonably regulated according to the flow discharge to improve the sediment delivery capacity and reduce sedimentation in the TGR,and to try to avoid situations where the flood retention time is close to 444 h.The depositional belt was discontinuous in the TGR and was mainly distributed in the broad reaches,and only slight erosion or deposition occurred in the gorge reaches.Sedimentation in the broad and gorge reaches accounted for 93.8% and 6.2% of the total sedimentation,respectively.The estuarine reach located in the fluctuating backwater area experienced alternate erosion-deposition,with a slight accumulative deposition in the curved reach.Sedimentation mainly occurred in the perennial backwater area.The insight gained in this study can be conducive to directly understanding of large reservoir sedimentation and mechanism of channel adjustment in the reservoir region in the main channel of large river. | Xiaoya Tang Sichen Tong Guoxian Huang Guangxiang Xu Xinghua Li Kun Lei Shiming Yao | 2021 | International Journal of Sediment Research2021，36，2： | 3 |
| 11 | Oncogenic viruses and cancer显示文摘This special issue of the journal is dedicated to the important topic of oncogenic viruses and cancer.It contains seven review articles covering all known oncogenic viruses except for human T-lymphotropic virus type1(HTLV-1).These review articles are contributed by experts on specific viruses and their associated human cancers.Viruses account for about 20%of total human cancer cases.Although many viruses can cause various tumors in animals,only seven of | Guangxiang George Luo Jing-hsiung James Ou | 2015 | Virologica Sinica2015，30，2： | 3 |
| 12 | Temporal trends of cirrhosis associated conditions显示文摘BACKGROUND Chronic liver disease and cirrhosis is the 12^(th) leading cause of death in the United States. Patients with decompensated-cirrhosis, especially with hepatic encephalopathy/coma(HC), have a higher rate of early readmission and contribute to higher healthcare cost.AIM To evaluate the national inpatient trends of discharges, mortalities and financial impacts associated with four common conditions of cirrhosis.METHODS The publicly available Healthcare Cost and Utilization Project National Inpatient Sample database was utilized to examine the temporal trends of total number of discharges, mortalities and inpatient costs related to hospitalization with a primary diagnosis of HC, transjugular intrahepatic portosystemic shunt(TIPS),esophageal varices with bleeding(EV) and spontaneous bacterial peritonitis(SBP) from 2005 to 2014. The ten-year temporal trends were assessed using simple linear regressions and multiple regression analysis. Two-sided P < 0.05 was considered statistically significant.RESULTS From 2005 to 2014, the total number of discharges with cirrhosis-associated complications trended up for HC, SBP and EV(HC by 70% increase, P < 0.0001;SBP by 819% increase, P = 0.0002; EV by 9% increase, P = 0.016), but not for TIPS(P = 0.90). HC related to viral hepatitis showed faster increase by 357%(P <0.0001) in comparison to HC not related to viral hepatitis by 33 %(P = 0.0006).Overall, in-hospital mortality rates for each condition decreased from 2005 to2014(HC by 29% reduction, P = 0.0024; SBP by 26% reduction, P = 0.0038; TIPS by 32% reduction, P = 0.021) except for EV(P = 0.34). After adjustment for inflation, aggregate cost of hospitalization for EV, HC, and SBP significantly increased by 20%, 86%, and 980%, respectively, from 2005 to 2014(all P < 0.02),while TIPS had trend toward decreasing cost by 3%(P = 0.95).CONCLUSION The number of hospitalizations and costs for some of the cirrhosis-associated conditions increased. However, the inpatient mortality rates for most of these conditions decreased. | Tomoki Sempokuya Guangxiang Zhang Kazuma Nakagawa | 2019 | World Journal of Hepatology2019，11，1： | 2 |
| 13 | Hepatitis C Virus Infects the Endothelial Cells of the Blood-Brain Barrier显示文摘 | Nicola F. Fletcher Garrick K. Wilson Jacinta Murray Ke Hu Andrew Lewis Gary M. Reynolds Zania Stamataki Luke W. Meredith Ian A. Rowe Guangxiang Luo Miguel A. Lopez–Ramirez Thomas F. Baumert Babette Weksler Pierre–Olivier Couraud Kwang Sik Kim Ignacio A. R | 2012 | Gastroenterology2012，，3： | 2 |
| 14 | A Cheeger-Mller Theorem for Symmetric Bilinear Torsions显示文摘作者为 Burghelea 和 Haller 为带非退化的对称的双线性的形式的扁平的向量捆介绍的复杂珍视的分析扭转建立一条 Cheeger-M ü l ler 类型定理。作为后果,他们证明 Burghelea 大厅在完整的概论推测,它给分析解释(平方) Turaev 扭转。 | Guangxiang SU Weiping ZHANG | 2008 | Chinese Annals of Mathematics,Series B2008，29，4： | 2 |
| 15 | Protective Effects of Ciliary Neurotrophic Factor on Denervated Skeletal Muscle显示文摘Summary: To study the effects of ciliary neurotrophic factor (CNTF) on denervated skeletal muscle atrophy and to find a new approach to ameliorate atrophy of denervated muscle, a model was established by cutting the right sciatic nerve in 36 Wistar mice, with the left side serving as control. Then they were divided into two groups randomly. CNTF (1 U/ml) 0.1 ml was injected into the right tibial muscle every day in experimental group, and saline was used into another group for comparison. The muscle wet weight, muscle total protein, Ca 2+, physiological response and morphology were analyzed on the 7th, 14th and 28th day after operation. Our results showed that compared to control group, there was a significant increase in muscle wet weight, total protein, Ca 2+, muscle fiber cross-section area in CNTF group (P<0.05). CNTF could ameliorate the decrease of tetanic tension (PO), post-tetanic twitch potentiation (PTP), and the prolonged muscle relaxation time (RT) caused by denervation (P<0.05). The motor end-plate areas 7 days and 14 days after denervation was similar (P>0.05), but significantly larger 28 days after the denervation (P<0.05). Our results suggest that CNTF exerts myotrophic effects by attenuating the morphological and functional changes associated with denervation of rat muscles and has protective effects on denervated muscle and motor end plate. | HUANG Shilong(黄仕龙) WANG Fabin(王发斌) HONG Guangxiang(洪光祥) WAN Shengxiang(万圣祥) KANG Hao(康皓) | 2002 | Journal of Huazhong University of Science and Technology(Medical Sciences)2002，22，2： | 2 |
| 16 | Study on Supporting of Seam Roadways in Deeply Inclined Coal Seams显示文摘Based on the present problems of the support method of gateways in complex surrounding rock in steeply inclined seams, this paper discusses the support selection of lasting gateways in steeply inclined seams, and evaluates the support effects. It draws the conclusion that the support of bolt-mesh-anchor is the most effective support of this sort of gateways by using scale model simulation in lab and practice application.The support effects of practice application are satisfactory. It will give a beneficial reference to other analogical mine and has an extensive application prospect. | Luo Yong Shen Zhaowu Xie Guangxiang Liu Quanming | 2006 | 工程科学(英文版)2006，4，1： | 2 |
| 17 | The effects of carbonization time on the properties and structure of PAN-based activated carbon hollow fiber显示文摘 | JUNFEN SUN GUANGXIANG WU QINGRUI WANG | 2005 | Journal of Materials Science2005，40，3： | 1 |
| 18 | Two-way amplify- and-forward relaying with carrier offsets in the absence of CSI : differential modulation-based schemes 显示文摘 | Wu Zhuo Li Guangxiang Wang Tao | 2014 | EUR- ASIP Journal on Wireless Communications and Networ- king2014，2014，： | 1 |
| 19 | Bipolar hemiarthroplasty compared with internal fixation for unstable intertroehanterie fracture in elderly patients 显示文摘 | Shen Jun Wang Donglai Chen Guangxiang | 2012 | J Orthop Sci2012，17，6： | 1 |
| 20 | Wnt-5a regulates proliferation in lung cancer cells显示文摘 | Ying Huang Guangxiang Liu Bo Zhang Gang Xu Wei Xiong Heping Yang | 2010 | Oncology Reports2010，，1： | 1 |
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