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| 1 | Transcriptional and signaling regulation in neural crest stem cell-derived melanocyte development: do all roads lead to Mitf?显示文摘人的 neurocristopathies 包括神经的冠(NC ) 的很多症候群,肿瘤,和 dysmorphologies 干细胞衍生物。在最近的年里,许多白看到基因在源于 NC 茎的 neurocristopathies 与 hypopigmentary 混乱和聋被联系了导出房间的 melanocyte 缺乏在开发期间。这些包括 PAX3, SOX10, MITF, SNAI2, EDNRB, EDN3,工具包,和 KITL。最近的研究在 melanocyte 开发在交往的基因的复杂网络揭示了令人吃惊的新卓见进 MITF 的一个中央角色。在这个观点,我们提供一些当前的调查结果的概述并且在 NC 茎期间探索这些基因的复杂功能的角色导出房间的 melanocyte 开发。 | Ling Hou William J Pavan | 2008 | Cell Research2008，18，12： | 30 |
| 2 | Intracellular HMGB1 as a novel tumor suppressor of pancreatic cancer显示文摘尽管有最近的进展, oncogenic K 地岬驾驶的胰腺的 ductal 腺癌(PDAC ) 在最致命的人的癌症之中留在现代医学。PDAC 的致病对内在的染色体不稳定性和外来的发炎激活部分可归因。然而,在在胰腺的 tumorigenesis 的这二个事件之间的分子的连接充分还没被建立了。这里,我们证明(HMGB1 ) 细胞内部的高活动性组盒子 1 显著地压制 oncogenic 由禁止染色体的 K-Ras-driven 胰腺的 tumorigenesis 调停不稳定性的支持 inflammatory nucleosome 版本。任何一个单身者的有条件的基因脱离或在胰的 HMGB1 的两等位基因在出生使老鼠变为极其敏感到先锋损害的 oncogenic K-Ras-driven 开始,包括胰腺的 intraepithelial 瘤, intraductal 乳突的 mucinous 瘤,和 mucinous 膀胱的瘤。在胰的 HMGB1 的损失与染色体重新整理和 telomere 畸形描绘的氧化 DNA 损坏和 chromosomal 不稳定性被联系。这些导致煽动性的 nucleosome 版本并且宣传 K-Ras-driven 胰腺的 tumorigenesis。细胞外的 nucleosomes 支持 interleukin 6 (IL-6 ) 由渗入 macrophages/neutrophils 的分泌物并且提高在胰腺的损害表明激活的 oncogenic K 地岬。到 IL-6 或 histone H3 或为先进 glycation 的受体的大美人的抵销的抗体结束产品都限制表明激活的 K 地岬,阻止癌症开发和转移 / 侵略,并且延长在 Pdx1-Cre 的动物幸存; K 地岬 G12D/+;Hmgb1/ 鼠标。由 glycyrrhizin 的 HMGB1 损失的药理学抑制在煽动性的条件下面在老鼠限制 oncogenic K-Ras-driven tumorigenesis。减少在 PDAC 病人的 HMGB1 的原子、全部的细胞的表示与差的全面幸存相关,在 PDAC 与预示、治疗学的关联作为新奇肿瘤 suppressor 支持细胞内部的 HMGB1。 | Rui Kang Yangchun Xie Qiuhong Zhang Wen Hou Qingping Jiang Shan Zhu Jinbao Liu Dexing Zeng Haichao Wang David L Bartlet Timothy R Billiar Herbert J Zeh III Michael T Lotze Daolin Tang | 2017 | Cell Research2017，27，7： | 22 |
| 3 | Metabolic syndrome and coronary artery calcification: a community-based natural population study显示文摘 | CAO Hui-li CHEN Xiong-biao LU Jin-guo HOU Zhi-hui TANG Xiang GAO Yang YU Fang-fang JIANG Shi-liang ZHAO Lian-cheng LI Ying Matthew J Budoff Robert Detrano LU Bin | 2013 | Chinese Medical Journal2013，，24： | 4 |
| 4 | P-wave velocities of alkaline olivine basalt at high pressure and temperature and its controlling factors显示文摘SEISMIC wave inversion is one of the most important means for us to recognize the compositionand structure of the Earth’s interior.Although the experimental techniques of elastic wave ve-locity measurement at in situ high pressure and temperature develop very fast in recent | Song, MS Xie, HS Zhang, YM Hou, W Xu, J Xu, YS | 1997 | Chinese Science Bulletin1997，42，9： | 3 |
| 5 | Variations in Wool Growth with Nutrient Supply in Northern China显示文摘Field studies on essessment of nutritional status of the grazing sheep were carried out in each of the three major grassland regions, the eastern Inner Mongolia and beyond grassland, the Inner Mongolia - Ningxia - Gansu grassland and the Xinjiang grassland, in northern China. The results obtained showed that the wool production of fine wool sheep in these regions varied between regions and seasons, with similar seasonal patterns in all regions and that reducing the seasonal variations in nutrient supply would enhance wool production substantially. Nutritional limitations to wool growth of the grazing sheep in these regions were suggested, those were: the shortage of protein supply in winter and early spring; the poor quality of much of the pasture and the hay used as supplements, the low energy intake during winter which probably necessitated the use of body stores to maintain body temperature. | D X Lu,Iner(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)Z C Feng,(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)H R Wang,(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)R Z Yang,(Xinjiang Institute of Animal Science.Xinjiang Academy of Animal Science.Yiu Hou Road.Urumqi.Xinjiang Uygur Autonomous Region PRC)C T Ma,(Chinese Academy of Agricultural Sciences.Lanzhou.Gansu.PRC)D B Purser,(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014)J R Lindsay(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014)D W Peter(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014) | 1997 | 畜牧与饲料科学1997，22，S1： | 3 |
| 6 | Cyclic rapid warming on centennial-scale revealed by a 2650-year stalagmite record of warm season temperature 显示文摘 | Tan M Liu T S Hou J | 2003 | Geophysical Research Letters2003，30，： | 2 |
| 7 | 查看详情显示文摘 | Zhao C T Hou J N Zhang X Zhu W.Xu M | | 高分子科学(英文版)0，，： | 2 |
| 8 | Benign Congenital Muscular Dystrophy with Autosomal Dominant Heredity显示文摘Benign congenital muscular dystrophy with autsomal dominant heredity of a pedigree is reported.The grandfather. | Hou Huiguang, et al. Dept Neuro Ganquan Hospital, Shanghai Railway Med Col. Changhai 200061. Chin J Neuro Psych 1994 | 1995 | Chinese Medical Journal1995，，2： | 2 |
| 9 | Integration of Pricing with Call Admission Control to Meet QoS requirements in Cellular Networks显示文摘 | HOU J YANG J | 2002 | IEEE Transactions on Parallel and Distributed Systems2002，13，9： | 2 |
| 10 | Hepatology Research|预测慢性乙型肝炎患者何时停用核苷(酸)类似物及停药后乙型肝炎复发的生物标志物显示文摘HBV感染是一个严重的全球健康问题。目前有两大类药物被推荐用于治疗HBV感染,包括核苷(酸)类似物和干扰素。由于接受核苷(酸)类似物治疗的患者较难实现停药后功能性治愈,需要长期的核苷(酸)类似物治疗;并且一旦过早停药,复发和肝炎恶化的可能性会增加。近年研究表明,HBeAg阴性患者停止长期核苷(酸)类似物治疗后,相对较高比例的患者保持了无治疗缓解状态,甚至实现了HBsAg清除。这些发现对终身服用核苷(酸)类似物的必要性提出了挑战。南方医科大学南方医院的Luo等对可以预测核苷(酸)类似物停药的病毒学指标进行了综述。检索的数据库为PubMed,使用慢性乙型肝炎、预测、停药等关键词按条件进行检索,最终对84篇文章进行了综述。 | 蒋德科 LUO M ZHOU B HOU J | 2022 | 临床肝胆病杂志2022，38，6： | 2 |
| 11 | Prediction of impact damage in composite plates显示文摘 | Hou J P Petrinic N Ruiz C Hallett S R | 2006 | Composites Science and Technology2006，60，： | 1 |
| 12 | Atomic bonding of precipitate and phase transformation of Al-Cu-Mg alloy 显示文摘 | CAO Y J HOU X H MO Q F | 2007 | J Alloys Compd2007，441，： | 1 |
| 13 | A Survey on Multicast Routing and Its QoS Extensions: Problems, Algorithms and Protocols显示文摘 | Wang B Hou C J | 2000 | IEEE Network Magazine2000，14，1： | 1 |
| 14 | Maintaining Sensing Coverage and Connectivity in Large Sensor Networks 显示文摘 | Zhang H Hou J C | 2005 | Ad Hoc & Sensor Networks2005，1，： | 1 |
| 15 | A Extended Class of Time-Continuous Branching Processes显示文摘 | Zhang H J and Hou Z T | 1999 | Submitted,19991999，1999，： | 1 |
| 16 | A new approach to edge detection显示文摘 | Wei G W | 2002 | Pattern Recognition2002，35，7： | 1 |
| 17 | The effect of excess Zn on mineral nutrition and antioxidative response in rapeseed seedlings显示文摘 | WANG CH ZHANG S H WANG P F HOU J ZHANG W J LI W LIN ZH P | 2009 | Chemosphere2009，75，： | 1 |
| 18 | Enhanced adhesion of diamond-like carbon films with a compositional-graded intermediate layer显示文摘 | Hou Q R Gao J | 1999 | Applied Physics A:Materials Science & Processing1999，680，： | 1 |
| 19 | Toward secure distributed spectrum sensing in cognitive radio networks 显示文摘 | Chen R Park J M Hou Y T | 2008 | IEEE Commu- nication Magazine2008，4，： | 1 |
| 20 | Effect of SO2 on V2O5/ ACF catalysts for NO reduction with NH3 at Low temperature显示文摘 | Hou Y Q Huang Z G Guo S J | 2009 | Catal Commun2009，10，11： | 1 |
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