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| 1 | Differing coping mechanisms, stress level and anorectal physiology in patients with functional constipation显示文摘AIM: To investigate coping mechanisms, constipation symptoms and anorectal physiology in 80 constipated subjects and 18 controls.METHODS: Constipation was diagnosed by Rome Ⅱ criteria.Coping ability and anxiety/depression were assessed by validated questionnaires. Transit time and balloon distension test were performed.RESULTS: 34.5% patients were classified as slow transit type of constipation. The total colonic transit time (56 h vs 10 h, P<0.0001) and rectal sensation including urge sensation (79 mL vs 63 mL, P = 0.019) and maximum tolerable volume (110 mL vs95 mL, P = 0.03) differed in patients and controls. Constipated subjects had significantly higher anxiety and depression scores and lower SF-36 scores in all categories. They also demonstrated higher scores of'monitoring' coping strategy (14+6 vs9+3, P = 0.001),which correlated with the rectal distension sensation (P = 0.005), urge sensation (P=0.002), and maximum tolerable volume (P = 0.035). The less use of blunting strategy predicted slow transit constipation in both univariate (P = 0.01) and multivariate analysis (P = 0.03).CONCLUSION: Defective or ineffective use of coping strategies may be an important etiology in functional constipation and subsequently reflected in abnormal anorectal physiology. | Annie OO Chan Cecilia Cheng Wai Mo Hui Wayne HC Hu Nina YH Wong KF Lam Wai Man Wong Kam Chuen Lai Shiu Kum Lam Benjamin CY Wong | 2005 | World Journal of Gastroenterology2005，11，34： | 92 |
| 2 | Genetic polymorphisms of phase II metabolic enzymes and lung cancer susceptibility in a population of Central South China显示文摘 | Chen HC Cao YF Hu WX | 2006 | Dis Markers2006，22，3： | 1 |
| 3 | Prediction of fluid responsiveness in acute respiratory distress syndrome patients ventilated with low tidal volume and high positive end-expiratory pressure显示文摘 | Huang CC Fu JY Hu HC | 2008 | Crit Care Med2008，36，10： | 1 |
| 4 | Genetic polymorphisms of phase II metabolic enzymes and lung cancer susceptibility in a population of Central South China显示文摘 | Chen HC Cao YF Hu WX | 2006 | Dis Markers2006，22，3： | 1 |
| 5 | Spiral CT of bronchial arteries in chronic thromboembolism 显示文摘 | Kauczor HU Schwickert HC Mayer E | 1994 | J Comput Assist Tomogr1994，18，6： | 1 |
| 6 | Expression of class I and class I I major histocompatibility antigens on human epatocel-lular carcinoma 显示文摘 | Sung CH Hu CP Hsu HC | 1998 | J Clin Invest1998，83，2： | 1 |
| 7 | Pulmonary hypertension in patients with chronic pulmonary thromboembolism: chest radiograph and CT evaluation before and after surgery显示文摘 | Schmidt HC Kauczor HU Schild HH | 1996 | European Radiology1996，6，6： | 1 |
| 8 | Procalcitonin and C-reactive protein cannot differentiate bacterial or viral infection in COPDex- acerbation requiting emergency department visits显示文摘 | Chang CH Tsao KC Hu HC | 2015 | Int J Chron Obstruct Pulman Dis2015，10，4： | 1 |
| 9 | Polymorptfisms of the parkin gene in sporadic Parkinson's disease among Chinese in Taiwan显示文摘 | Hu CJ Sung SM Liu HC | 2000 | Eur Neurol2000，44，2： | 1 |
| 10 | High expression of periostin is dra- matically associated with metastatic potential and poor prognosis of patients with osteosarcoma 显示文摘 | Hu F Wang W Zhou HC | 2014 | World J Surg Oncol2014，12，： | 1 |
| 11 | Thymosin beta4 triggers an epi- thelial- mesenchymal transition in colorectal carcinoma by upregulating integrin-linked kinase 显示文摘 | Huang HC Hu CH Tang MC | 2007 | Oncogene2007，26，19： | 1 |
| 12 | S-adenosylhomocysteine promotes the invasion of C6 glioma cells via increased secretion of matrix metalloproteinase 2 in murine microglial BV2 cells显示文摘 | Lin HC Song TY Hu ML | 2009 | ToxicolSci2009，112，： | 1 |
| 13 | Genetic polymorphisms of metabolic enzymes CYP1 A1, CYP2D6, GSTM1 and GSTTI and leukemia susceptibility 显示文摘 | Chen HC Hu WX Liu QX | 2008 | European Journal of Cancer Prevention2008，17，3： | 1 |
| 14 | Thymosin beta4 triggers an epithelial-mesenchymal transition in colorectal carcinoma by upregulating integrin-linked kinase显示文摘 | Huang HC Hu CH Tang MC | 2007 | Oncogene2007，26，： | 1 |
| 15 | Prediction of fluid responsiveness in acute respiratory distress syndrome patients ventilated with low tidal volume and high positive end-expiratory pressure 显示文摘 | Huang CC Fu JY Hu HC etal | 2008 | Crit Care Med2008，36，10： | 1 |
| 16 | Obstrctive sleep apnea and increased risk of glaucoma: a population-based matched-co- hort study 显示文摘 | Lin CC Hu CC Ho JD Chin HW Lin HC | 2013 | Ophthalmology2013，120，8： | 1 |
| 17 | Phosphorylation of the Arabidopsis AtrbohF NADPH oxidase by OST1 protein kinase显示文摘 | Sirichandm C Gu D Hu HC Davanture M Lee S Djaoui M Valot B Zivy M Leung J Medrlt S Kwak JM | | 0，，18： | 1 |
| 18 | The caries-inhibiting effect of a fluoride drop program: a 3-year study on Chinese kindergarten children显示文摘 | Hu DY Wan HC Li SM | 1998 | Chin J Dent Res1998，1，3： | 1 |
| 19 | Responses of antioxidant gene,protein and enzymes to salinity stress in two genotypes of perennial ryegrass (Lolium perenne) differing in salt tolerance显示文摘 | Hu LX Li HY Pang HC Fu JM | | 0，，02： | 1 |
| 20 | The effect of statins in chronic heart failure : beyond its cholesterol-lowering effect 显示文摘 | Hu T Wang HC | 2012 | Heart2012，98，2： | 1 |
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