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| 1 | No difference in mortality among ALPPS,two-staged hepatectomy,and portal vein embolization/ligation:A systematic review by updated traditional and network meta-analyses显示文摘Background:There is an ongoing debate on the feasibility,safety,and oncological efficacy of the associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)technique.The aim of this study was to compare ALPPS,two-staged hepatectomy(TSH),and portal vein embolization(PVE)/ligation(PVL)using updated traditional meta-analysis and network meta-analysis(NMA).Data sources:Electronic databases were used in a systematic literature search.Updated traditional metaanalysis and NMA were performed and compared.Mortality and major morbidity were selected as primary outcomes.Results:Nineteen studies including 1200 patients were selected from the pool of 436 studies.Of these patients,315(31%)and 702(69%)underwent ALPPS and portal vein occlusion(PVO),respectively.Ninetyday mortality based on updated traditional meta-analysis,subgroup analysis of the randomized controlled trials(RCTs),and both Bayesian and frequentist NMA did not demonstrate significant differences between the ALPPS cohort and the PVE,PVL,and TSH cohorts.Moreover,analysis of RCTs did not demonstrate significant differences of major morbidity between the ALPPS and PVO cohorts.The ALPPS cohort demonstrated significantly more favorable outcomes in hypertrophy parameters,time to operation,definitive hepatectomy,and R0 margins rates compared with the PVO cohort.In contrast,1-year disease-free survival was significantly higher in the PVO cohort compared to the ALPPS cohort.Conclusions:This study is the first to use updated traditional meta-analysis and both Bayesian and frequentist NMA and demonstrated no significant differences in 90-day mortality between the ALPPS and other hepatic hypertrophy approaches.Furthermore,two high quality RCTs including 147 patients demonstrated no significant differences in major morbidity between the ALPPS and PVO cohorts. | Paschalis Gavriilidis Robert P Sutcliffe Keith J Roberts Madhava Pai Duncan Spalding Nagy Habib Long R Jiao Mikael H Sodergren | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，5： | 6 |
| 2 | The combination of intravitreal triamcinolone and phacoemulsification surgery in patients with diabeticfoveal oedema and cataract 显示文摘 | HABIB M S CANNON P S STEEL D H | 2005 | BMC Ophthalmol2005，5，： | 1 |
| 3 | Characterisitcs of flow field and water concentration in a horizontal dedleg 显示文摘 | Habib M A Badr H M Said S A M | 2005 | Heal Mass Transfer2005，41，： | 1 |
| 4 | Opposite clear corneal incisions on the steep meridian in phacoemulsification:early effects on the cornea显示文摘 | Tadros A Habib M Tejwani D von Lany H Thomas P | 2004 | J Cataract Refract Surg2004，30，2： | 1 |
| 5 | Effect of planting tlmes,maturlty stages and iba in stem cuttings of bougainvillea (Bougainvilleas spectabilis ) 显示文摘 | Habib M A Alam K H Khanam M H A etal | 2007 | International Journal of Sustainable Agricultural Technology2007，3，4： | 1 |
| 6 | Motor blocking mini- mum local anesthetic concentrations of bupivacaine, levobupiva caine, and ropivacaine in labor显示文摘 | Lacassie H J Habib AS Lacassie HP | 2007 | Reg Anesth Pain Med2007，32，4： | 1 |
| 7 | Pro- duction and response of human prostate cancer cell lines to granulocyte macrophage-eolony stimulating factor显示文摘 | Lang S H Miller W R Duncan W Habib F K | 1994 | Int J Cancer1994，59，： | 1 |
| 8 | Effect of geometry on flow fiehl and oil/water separation in vertical deadlegs 显示文摘 | Habib M A Said S A M Badr H M | 2005 | International Journal for Numerical Meth- ods in Heat & Fluid Flow2005，15，4： | 1 |
| 9 | Plant protease inhibitors: a defense strategy in plants 显示文摘 | HABIB H FAZILI K M | 2007 | Biotechnology and Molecular Biology2007，2，3： | 1 |
| 10 | Cyanidin 3-glucoside modulated cell cycle progression in liver precancerous lesion,in vivo study显示文摘BACKGROUND Cyanidin-3-O-glucoside(cyan)exhibits antioxidant and anticancer properties.The cell cycle proteins and antimitotic drugs might be promising therapeutic targets in hepatocellular carcinoma.AIM To investigate the effect of cyan administration on cell cycle in hepatic precancerous lesion(PCL)induced by diethylnitrosamine/2-acetylaminofluorene(DEN/2-AAF)in Wistar rats.METHODS In vivo,DEN/2-AAF-induced hepatic PCL,rats were treated with three doses of cyan(10,15,and 20 mg/kg/d,for four consecutive days per week for 16 wk).Blood and liver tissue samples were collected for measurement of the followings;alpha fetoprotein(AFP)liver function and RNA panel differential expression was evaluated via real time polymerase chain reaction.Histopathological examination of liver sections stained with H&E and immunohistochemical study using glutathione S-transferase placental(GSTP)and proliferating cell nuclear antigen(PCNA)antibodies were assessed.RESULTS Cyan administration mitigated the effect of DEN/2-AFF induced PCL,decreased AFP levels,and improved liver function.Remarkably,treatment with cyan dose dependently decreased the long non-coding RNA MALAT1 and tubulin gamma 1 mRNA expressions and increased the levels of miR-125b,all of which are involved in cell cycle and mitotic spindle assembly.Of note,cyan decreased GSTP foci percent area and PCNA positively stained nuclei.CONCLUSION Our results indicated that cyan could be used as a potential therapeutic agent to inhibit liver carcinogenesis in rat model via modulation of cell cycle. | Marwa Matboli Amany H Hasanin Reham Hussein Sarah El-Nakeep Eman K Habib Rawan Ellackany Lobna A Saleh | 2021 | World Journal of Gastroenterology2021，27，14： | 1 |
| 11 | Efficient oil palm total RNA extraction with a total RNA extraction kit 显示文摘 | Habib SH Saud HM Kausar H | 2014 | Genet Mol Res2014，13，2： | 1 |
| 12 | 显示文摘 | Habib A H Tomy C V Nigam A K | 2005 | Physica B2005，362，14： | 1 |
| 13 | Cement leakage and filling pattern study of low viscous vertebroplastic versus high viscous confidence cement显示文摘 | HABIB M SERHAN H MARCHEK C et at | 2010 | SAS J2010，4，1： | 1 |
| 14 | Biological control of the tick fowl Argas persicargas persicus 显示文摘 | Habib S M | | J Pest Science0，74，12： | 1 |
| 15 | Using smartphones and sensor technologies to automate collection of travel data显示文摘 | Abdulazim T Abdelgawad H Habib K | 2013 | Transportation Research Board2013，，2383： | 1 |
| 16 | Regulation of cycloogenases by protein kinase C. Evidence agaist the importance of direct enzyme phosphorylation显示文摘 | Vezza R Habib A Li H | | 0，，： | 1 |
| 17 | Mag- netic nanoparticle-based solder composites for electronic packaging applications 显示文摘 | Xu S Habib A H Pickel A D McHenry M E | 2015 | Progress in Materials Sci- ence2015，67，： | 1 |
| 18 | 'The honeymoon phase' in children with type 1 diabetes mellitus: frequency, duration, and influential factors显示文摘 | Abdul-Rasoul M Habib H A1-Khouly M | 2006 | Pediatr Diabetes2006，7，2： | 1 |
| 19 | Plant growth inhibitory activity of Lycoris radiate Herb and the possible involvement of lycorine as an allelochemical显示文摘 | ZAHIDA I HABIB N SYUNTARO H | 2006 | Weed Biology and Management2006，6，4： | 1 |
| 20 | Numerical investigation of erosion threshold ve- locity in a pipe with sudden contraction显示文摘 | BADR H M HABIB M A BEN-MANSOUR R | 2005 | Comput- ers & Fluids2005，34，6： | 1 |
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