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| 1 | YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA显示文摘 | Hailing Shi Xiao Wang Zhike Lu Boxuan S Zhao Honghui Ma Phillip J HSU Chang Liu Chuan He | 2017 | Cell Research2017，27，3： | 156 |
| 2 | Numerical analysis and simulation of Czochralski growth processes for large diameter silicon crystals显示文摘Numerical analysis and simulation have been an effective means to develop the advanced growth technology and to control the defects type, size and density for silicon crystals of 300 mm and beyond. In the present paper, numerical analysis of the melt flow in the Czochralski (CZ) crystal growth configuration, the three dimensional (3D) modeling, the simulation of melt flow under the magnetic field, the inverse modeling and the time-dependent simulation are reviewed. Fi nally, comparison of numerical analysis with experimental measurements is discussed. | TU Hailing XIAO Qinghua GAO Yu ZHOU Qigang ZHANG Guohu CHANG Qing | 2007 | Rare Metals2007，26，6： | 5 |
| 3 | Comparison of Clinical and Epidemiological Characteristics of Asymptomatic and Symptomatic SARS-CoV-2 Infection in Children显示文摘To understand the epidemiological and clinical features of the symptomatic and asymptomatic pediatric cases of COVID-19,we carried out a prospective study in Shanghai during the period of January 19 to April 30,2020.A total of 49 children(mean age 11.5±5.12 years)confirmed with SARS-CoV-2 infection were enrolled in the study,including 11(22.4%)domestic cases and 38(77.6%)imported cases.Nine(81.8%)local cases and 12(31.6%)imported cases had a definitive epidemiological exposure.Twenty-eight(57.1%)were symptomatic and 21(42.9%)were asymptomatic.Neither asymptomatic nor symptomatic cases progressed to severe diseases.The mean duration of viral shedding for SARS-CoV-2 in upper respiratory tract was 14.1±6.4 days in asymptomatic cases and 14.8±8.4 days in symptomatic cases(P>0.05).Forty-five(91.8%)cases had viral RNA detected in stool.The mean duration of viral shedding in stool was 28.1±13.3 days in asymptomatic cases and 30.8±18.6 days in symptomatic participants(P>0.05).Children<7 years shed viral RNA in stool for a longer duration than school-aged children(P<0.05).Forty-three(87.8%)cases had seropositivity for antibodies against SARS-CoV-2 within 1–3 weeks after confirmation with infection.In conclusion,asymptomatic SARS-CoV-2 infection may be common in children in the community during the COVID-19 pandemic wave.Asymptomatic cases shed viral RNA in a similar pattern as symptomatic cases do.It is of particular concern that asymptomatic individuals are potentially seed transmission of SARS-CoV-2 and pose a challenge to disease control. | Jiehao Cai Xiangshi Wang Jun Zhao Yanling Ge Jin Xu He Tian Hailing Chang Aimei Xia Jiali Wang Jinqiang Zhang Zhongqiu Wei Jingjing Li Chuning Wang Jianshe Wang Qirong Zhu Xiaowen Zhai Mei Zeng | 2020 | Virologica Sinica2020，35，6： | 4 |
| 4 | Nimbus-7 SMMR de- rived global snow cover parameters显示文摘 | Chang A T C Foster J L Hail D K | 1987 | Annals of Glaciology1987，9，： | 1 |
| 5 | Mild Cytokine Elevation, Moderate CD4^+ T Cell Response and Abundant Antibody Production in Children with COVID-19显示文摘Children with Coronavirus Disease 2019(COVID-19) were reported to show milder symptoms and better prognosis than their adult counterparts, but the difference of immune response against SARS-CoV-2 between children and adults hasn’t been reported. Therefore we initiated this study to figure out the features of immune response in children with COVID-19.Sera and whole blood cells from 19 children with COVID-19 during different phases after disease onset were collected.The cytokine concentrations, SARS-CoV-2 S-RBD or N-specific antibodies and T cell immune responses were detected respectively. In children with COVID-19, only 3 of 12 cytokines were increased in acute sera, including interferon(IFN)-cinduced protein 10(IP10), interleukin(IL)-10 and IL-16. We observed an increase in T helper(Th)-2 cells and a suppression in regulatory T cells(Treg) in patients during acute phase, but no significant response was found in the IFN-cproducing or tumor necrosis factor(TNF)-a-producing CD8?T cells in patients. S-RBD and N IgM showed an early induction, while S-RBD and N IgG were prominently induced later in convalescent phase. Potent S-RBD IgA response was observed but N IgA seemed to be inconspicuous. Children with COVID-19 displayed an immunophenotype that is less inflammatory than adults, including unremarkable cytokine elevation, moderate CD4?T cell response and inactive CD8?T cell response, but their humoral immunity against SARS-CoV-2 were as strong as adults. Our finding presented immunological characteristics of children with COVID-19 and might give some clues as to why children develop less severe disease than adults. | Ran Jia Xiangshi Wang Pengcheng Liu Xiaozhen Liang Yanling Ge He Tian Hailing Chang Hao Zhou Mei Zeng Jin Xu | 2020 | Virologica Sinica2020，35，6： | 1 |
| 6 | Evaluation of potential reference genes for qRT-PCR studies in human hepatoma cell lines treated with TNF-α显示文摘在这研究,八候选人引用基因的表达式, B2M , ACTB , GAPDH , HMBS , HPRT1 , TBP , UBC ,和 YWHAZ ,被检验鉴别由量的反向的抄写聚合酶的最佳的引用基因锁住在二个人的 hepatoma 房间的分析衬里的反应( qRT-PCR ), BEL-7402 和 SMMC-7721 ,与肿瘤坏死因素对待--(TNF-)为不同时间时期。这些基因的表示稳定性被三个独立算法分析:geNorm, NormFinder,和 BestKeeper。结果证明 TBP 是在在当前的试验性的条件下面的 BEL-7402 和 SMMC-7721 房间线的最稳定地表示的基因,并且参考基因的最佳的集合为精确正规化要求了,这是 TBP 和 HMBS,基于与 geNorm 决定的 pairwise 变化价值。UBC 和 ACTB 被一样的算法作为最不稳定的基因评价。我们的调查结果提供与 HMBS 同样内长的控制独自或在联合使用 TBP 能是为在与 TNF- 对待的人的 hepatoma 房间线使 qRT-PCR 数据正常化的一个可靠方法的证据。 | Chang Wu Xiang Wang Ming Zhong Hailing Liu Qiongqiong He Xiaojing Yang Jifang Wen Deyun Feng | 2013 | Acta Biochimica et Biophysica Sinica2013，45，9： | 1 |
| 7 | Stress relaxation of Si/Si_(1-x)Ge_x/Si structure prepared by ion implantation and subsequent annealing process显示文摘The stress relaxation of 74Ge+-implanted (100) silicon wafers was investigated. The implantation energy as a function of Si/Si1-xGex/Si struc-ture fluence and two kinds of thermal annealing were reported. The stress and stress relaxation after thermal annealing were calculated on the basis of Raman analysis, and were compared with those obtained from the calculation of virgin Si. | XU Wenting TU Hailing CHANG Qing XIAO Qinghua | 2011 | Rare Metals2011，30，3： | 0 |
| 8 | Detection and classification of pesticide residues in dandelion(Taraxacum officinale L.)by electronic nose combined with chemometric approaches显示文摘In this study,for the first time a suitable pesticide residue detection system for dandelion(Taraxacum officinale L.)was established based on electronic nose to determine and study the concentration of pesticide residue in dandelion.Dandelions were sprayed with different concentrations of pesticides(avermectin,trichlorfon,deltamethrin,and acetamiprid),respectively.Data collection was performed by application of an electronic nose equipped with 12 metal oxide semiconductor(MOS)sensors.Data analysis was conducted using different methods including BP neural network and random forest(RF)as well as the support vector machine(SVM).The results showed the superior effectiveness of SVM in discrimination and classification of non-exceeding maximum residue limits(MRLs)and exceeding MRLs standards.Moreover,the model trained by SVM has the best performance for the classification of pesticide categories in dandelion,and the classification accuracy was 91.7%.The results of this study can provide reference for further development and construction of efficient detection technology of pesticide residues based on electronic nose for agricultural products. | Jianlei Qiao Xinmei Jiang Xiaohui Weng Hongbo Cui Chang Liu Yuanjun Zou Hailing Yu Yucai Feng Zhiyong Chang | 2023 | International Journal of Agricultural and Biological Engineering2023，16，5： | 0 |
| 9 | Production profile and comparison analysis of main toxin components of Fusarium oxysporum f.sp.sesami isolates with different pathogenicity levels显示文摘Fusarium wilt is a common fungal disease in sesame caused by Fusarium oxysporum f.sp.sesami(FOS).To determine the toxin production profiles of the FOS isolates with different pathogenicity levels under various culture conditions,we assessed the content variation of fusaric acid(FA)and 9,10-dehydrofusaric acid(9,10-DFA)produced by the four representative FOS isolates.Results indicated that the concentration of FA reached to a maximum of 2848.66μg/mL in Czapek medium,while 9,10-DFA was mainly produced in Richard and Lowcarbon Richard medium.The concentration of 9,10-DFA on Richard culture medium varied from 0μg/mL to 716.89μg/mL.Of the five culture media used in this study,Czapek culture medium was the most conductive to produce FA.FA production was significantly affected by culture medium,culture time,and their interactions.Results suggest that there is no correlation between toxin production and pathogenicity level of FOS isolates.These findings provide key information for the mechanism analysis of FOS-sesame interaction and pathogen control. | Hailing Li Yinghui Duan Guizhen Xu Shuxian Chang Ming Ju Yin Wu Wenen Qu Hengchun Cao Haiyang Zhang Hongmei Miao | 2023 | Oil Crop Science2023，8，2： | 0 |
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