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| 1 | eGPS 1.0: comprehensive software for multi-omic and evolutionary analyses显示文摘It has become increasingly challenging for researchers to analyze the exponentially expanding amount of multi-omic data.Here,we describe multi-functional software named evolutionary GenotypePhenotype Systems(eGPS)that enables users to perform comprehensive multiomic and evolutionary analyses.The eGPS combines the power of cloud computing and the advantage of desktop application,has a user-friendly graphic interface and is highly interactive. | Dalang Yu Lili Dong Fangqi Yan Hailong Mu Bixia Tang Xiao Yang Tao Zeng Qing Zhou Feng Gao Zhonghuang Wang Ziqian Hao Hongen Kang Yi Zheng Hongwei Huang Yuzhang Wei Wei Pan Yaochen Xu Junwei Zhu Shilei Zhao Ciran Wang Pengyu Wang Long Dai Mushan Li Li Lan Yiwei Wang Hua Chen Yi-Xue Li Yun-Xin Fu Zhen Shao Yiming Bao Fangqing Zhao Luo-Nan Chen Guo-Qing Zhang Wenming Zhao Haipeng Li | 2019 | National Science Review2019，6，5： | 4 |
| 2 | First experimental constraints on WIMP couplings in the effective field theory framework from CDEX显示文摘We present weakly interacting massive particles(WIMPs) search results performed using two approaches of effective field theory from the China Dark Matter Experiment(CDEX), based on the data from both CDEX-1B and CDEX-10 stages. In the nonrelativistic effective field theory approach, both time-integrated and annual modulation analyses were used to set new limits for the coupling of WIMP-nucleon effective operators at 90% confidence level(C.L.) and improve over the current bounds in the low mχregion. In the chiral effective field theory approach, data from CDEX-10 were used to set an upper limit on WIMP-pion coupling at 90% C.L. We for the first time extended the limit to the m_(χ)<6 GeV/c^(2) region. | Yi Wang Zhi Zeng Qian Yue LiTao Yang KeJun Kang YuanJing Li Mehment Agartioglu HaiPeng An JianPing Chang JingHan Chen YunHua Chen JianPing Cheng Cheng Yi Chiang WenHan Dai Zhi Deng ChangHao Fang XinPing Geng Hui Gong QiuJu Guo XuYuan Guo HongJian He Li He ShengMing He JinWei Hu TuChen Huang HanXiong Huang HaiTao Jia LiPing Jia Xi Jiang HauBin Li JianMin Li Jin Li MingXuan Li RenMingJie Li Xia Li YuLan Li Bin Liao FongKay Lin ShinTed Lin ShuKui Liu YanDong Liu Yu Liu YuanYuan Liu ZhongZhi Liu Hao Ma YuCai Mao QiYuan Nie JinHua Ning Hui Pan NingChun Qi Jie Ren XiChao Ruan ChangSong Shang Vivek Sharma Ze She Lakhwinder Singh Monoj Kumar Singh TianXi Sun ChangJian Tang WeiYou Tang Yang Tian GuangFu Wang Li Wang Qing Wang Yu Chen Wang YunXiang Wang Zhen Wang Henry Tsz-King Wong ShiYong Wu YuCheng Wu HaoYang Xing Yin Xu Tao Xue YuLu Yan Nan Yi ChunXu Yu HaiJun Yu JianFeng Yue Ming Zeng BingTao Zhang Lei Zhang FengShou Zhang ZhenYu Zhang KangKang Zhao MingGang Zhao JiFang Zhou ZuYing Zhou JingJun Zhu | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，8： | 3 |
| 3 | Prediction method for nutritional quality of Korla pear during storage显示文摘It is difficult to control the quality of Korla pear with different degrees of maturity during storage.Here,a method was proposed for predicting the effects of harvest maturity and cold storage time on the quality indices(soluble solid content(SSC)and Vitamin C(Vc)content)of Korla pear.The generalized regression neural network(GRNN)and adaptive neuro-fuzzy inference system(ANFIS)were employed to predict the quality changes of Korla fragrant pear fruit during storage.The results demonstrated that during cold storage the SSC in pears with 10%-70%harvest maturity showed continuous increases in the first 90 d of storage and then a slight decline thereafter,while that in pears with 80%and 90%harvest maturity exhibited slow decreases throughout the storage process.With the extension of storage time,the Vc content of pears with 10%-90%harvest maturity showed continuous decreases.The harvest maturity of Korla pear was extremely positively correlated with SSC and Vc content(p<0.01)in a given storage period.Storage time showed an extremely significant negative correlation with the Vc content(p<0.01)at the 40%-90%harvest maturity and an significant negative correlation with the Vc content(p<0.05)at the 10%-30%harvest maturity.At the 10%-70%harvest maturity,storage time showed a significant positive correlation with the SSC(p<0.05).The trained model could well predict the variation trend of quality indices of pear fruit during storage.The ANFIS with the input membership function of gbellmf had the best performance in predicting the SSC(RMSE=0.175;R2=0.98),and that with the input membership function of trimf exhibited the best performance in predicting Vc content(RMSE=0.075;R2=0.99).The research findings can provide reference for predicting the fruit nutritional quality at delivery and decision-making on the storage time of Korla fragrant pear. | Yang Liu Qiang Zhang Hao Niu Hong Zhang Haipeng Lan Yong Zeng Fuguo Jia | 2021 | International Journal of Agricultural and Biological Engineering2021，14，3： | 1 |
| 4 | Insights into a novel nitrogen removal process based on simultaneous anammox and denitrification(SAD) following nitritation with in-situ NOB elimination显示文摘Simultaneous anammox and denitrification(SAD) is an efficient approach to treat wastewater having a low C/N ratio;however, few studies have investigated a combination of SAD and partial nitritation(PN). In this study, a lab-scale up-flow blanket filter(UBF) and zeolite sequence batch reactor(ZSBR) were continuously operated to implement SAD and PN advantages, respectively. The UBF achieved a high total nitrogen(TN) removal efficiency of over 70% during the start-up stage(days 1–50), and reached a TN removal efficiency of 96%in the following 90 days(days 51–140) at COD/NH_(4)^(+)-N ratio of 2.5. The absolute abundance of anammox bateria increased to the highest value of 1.58 × 107copies/μL DNA;Comamonadaceae was predominant in the UBF at the optimal ratio. Meanwhile, ZSBR was initiated on day 115 as fast nitritation process to satisfy the influent requirement for the UBF. The combined process was started on day 140 and then lasted for 30 days, during the combined process, between the two reactors, the UBF was the main contributor for TN(66.5% ± 4.5%)and COD(71.8% ± 4.9%) removal. These results demonstrated that strong SAD occurred in the UBF when following a ZSBR with in-situ NOB elimination. This research presents insights into a novel biological nitrogen removal process for low C/N ratio wastewater treatment. | Jing Chen Jia Zeng Yiran He Shiquan Sun Haipeng Wu Yaoyu Zhou Zhenguo Chen Jianhui Wang Hong Chen | 2023 | Journal of Environmental Sciences2023，，3： | 1 |
| 5 | Effects of landscape structure, habitat and human disturbance on birds: A case study in East Dongting Lake wetland显示文摘 | Yujie Yuan Guangming Zeng Jie Liang Xiaodong Li Zhongwu Li Chang Zhang Lu Huang Xu Lai Lunhui Lu Haipeng Wu Xun Yu | 2014 | Ecological Engineering2014，，： | 1 |
| 6 | Engineering organoid microfluidic system for biomedical and health engineering:A review显示文摘In recent years,organoid technology,i.e.,in vitro three-dimensional(3D)tissue culture,has attracted increasing attention in biomedical engineering.Organoids are cell complexes induced by differentiation of stem cells or organ-progenitor cells in vitro using 3D culture technology.They can replicate the key structural and functional characteristics of the target organs in vivo.With the opening up of this new field of health engineering,there is a need for engineering-system approaches to the production,control,and quantitative analysis of organoids and their microenvironment.Traditional organoid technology has limitations,including lack of physical and chemical microenvironment control,high heterogeneity,complex manual operation,imperfect nutritional supply system,and lack of feasible online analytical technology for the organoids.The introduction of microfluidic chip technology into organoids has overcome many of these limitations and greatly expanded the scope of applications.Engineering organoid microfluidic system has become an interdisciplinary field in biomedical and health engineering.In this review,we summarize the development and culture system of organoids,discuss how microfluidic technology has been used to solve the main technical challenges in organoid research and development,and point out new opportunities and prospects for applications of organoid microfluidic system in drug development and screening,food safety,precision medicine,and other biomedical and health engineering fields. | Yifan Xing Junyu Liu Xiaojie Guo Haipeng Liu Wen Zeng Yi Wang Chong Zhang Yuan Lu Dong He Shaohua Ma Yonghong He Xin-Hui Xing | 2021 | Chinese Journal of Chemical Engineering2021，34，2： | 1 |
| 7 | A monoclonal antibody targeting neuropilin-1 inhibits adhesion of MCF7 breast cancer cells to fibronectin by suppressing the FAK/p130cas signaling pathway显示文摘 | Fanwei Zeng Fanghong Luo Sha Lv Haipeng Zhang Chang Cao Xiaoli Chen Shengyu Wang Zhe Li Xianjiang Wang Xiaofeng Dou Yujuan Dai Mingjun He Yafei Zhang Haiyan Lv Jianghua Yan Yuqiang Chen | 2014 | Anti-Cancer Drugs2014，，： | 1 |
| 8 | Comparative study of the structure, mechanical and thermomechanical properties of cellulose nanopapers with different thickness显示文摘 | Li Qiang Ohen Wenshuai Li Yanna Guo Xiaoyu Song Shan Wang Qingwen Liu Yixing Li Jian Yu Haipeng Zeng Jie | 2016 | Cellulose2016，23，2： | 1 |
| 9 | An Iron-Based High-Entropy Alloy with Highly Efficient Degradation for p-Nitrophenol显示文摘High-entropy alloys(HEAs)have attracted widespread attention due to their excellent mechanical properties.However,their functional properties arising from the supersaturated solid solution state can be improved.Advanced oxidation processes(AOPs)are considered to be an effective method for decomposing organic pollutants,and HEAs are proposed as effective candidates for AOP catalysts.Currently,several HEAs used for organic pollutant degradation are prepared through mechanical alloying.In this work,FeAlCoNi and FeAlCoNiB Fenton-like catalysts were prepared by single roll melt spinning and subsequent ball milling techniques.We found that the FeAlCoNiB HEA exhibits highly efficient degradation for p-nitrophenol(p-NP).The degradation efficiency of FeAlCoNiB is 120 times higher than that of FeAlCoNi,which confirms that boron functions effectively during the degradation process.FeAlCoNiB has a better degradation efficiency than pure iron powder and a degradation efficiency comparable to that of the amorphous Fe_(78)Si_(11)B_(11) alloy.Additionally,the degradation efficiency of FeAlCoNiB_(X) increases(k values from 0.13 to 0.55 min^(−1))when the boron content increases from an X value of 0.25 to 1.25.We speculate that Fe_(2)B favors the degradation process and promotes zero-valent iron to decompose organic pollutants through a galvanic cell effect.Possible p-NP degradation pathways are proposed after LC–MS analysis.This study provides a new series of HEA Fenton-like catalysts,which have the potential to be prepared into bulk devices for industrial applications. | Shenghui Xie Xiang Liao Xierong Zeng Haipeng Yang Liang He | 2022 | Acta Metallurgica Sinica(English Letters)2022，35，10： | 0 |
| 10 | Free-space beam shaping and steering based on a silicon optical phased array显示文摘In this study,we present a method for free-space beam shaping and steering based on a silicon optical phased array,which addresses the theoretical limitation of traditional bulk optics.We theoretically analyze the beam propagation properties with changes in the applied phase.Different beam profiles can be shaped by varying the phase combination,while a high-order quasi-Bessel beam can be generated with a cubic change to the phase modulation.The simulated results are validated further experimentally,and they match one another well.Beam steering can be achieved with a field of view as large as 140°,which has potential benefits for practical applications.The presented method is expected to have broad application prospects for optical communications,free-space optical interconnects,and light detection and ranging. | WENBO REN QINGQING LIANG JIJUN FENG HAIPENG LIU JIANHUA HU SHUO YUAN XINCHENG XIA WEI JIANG QIWEN ZHAN HEPING ZENG | 2023 | Photonics Research2023，11，12： | 0 |
| 11 | One-Pot Protolignin Extraction by Targeted Unlocking Lignin-Carbohydrate Esters via Nucleophilic Addition-Elimination Strategy显示文摘Protolignin extraction can facilitate structure elucidation and valorization of lignin in biorefinery,but is rather challenging due to the complex chemical bonds present.Here,we developed the in situ generated NH3-reline(IGNR)system to realize one-pot protolignin extraction from lignocellulose.In the IGNR system,reline consisting of choline chloride and urea acted as both a solvent and a nucleophile generator,and the nucleophilic addition-elimination mechanism was verified by model compound studies.The in situ generated NH3 could precisely cleave the lignin-carbohydrate esters in lignocellulose with a near-quantitative retention of carbohydrates.The extracted IGNR-Protolignin exhibited native lignin substructure with high molecular weight and highβ-O-4′content(41.5 per 100 aromatic units).In addition,the up-scaled kilogram reaction demonstrated the feasibility of the IGNR system for potential industrial application in a green and sustainable pathway.This work represents a breakthrough toward protolignin extraction in practice with the future goal of achieving total biorefinery. | Yuhan Lou Xinyue Sun Yanyan Yu Suqing Zeng Yilin Li Yongzhuang Liu Haipeng Yu | 2023 | Research2023，，4： | 0 |
| 12 | Construction method of quantitative evaluation model for the maturity of Korla fragrant pear显示文摘The maturity variation laws of Korla fragrant pears were explored for a quantitative evaluation of harvest maturity to solve the reasonable matching between harvest maturity of Korla fragrant pears and market quality demands.Korla fragrant pears from different harvesting periods were chosen as the research objects.Some quality indexes were chosen as the evaluation indexes per industry standards,including hardness,soluble solid content(SSC),single-fruit weight,fruit longitudinal diameter,fruit equatorial diameter,pericarp color parameters(L*,a*,and b*),and titratable acid.Variation data of these quality indexes with accumulated temperature were collected.Scores of several quality indexes were gained through principal component analysis.A mathematical model of scores and accumulated temperatures was constructed.On this basis,a quantitative maturity model of Korla fragrant pears was constructed.Results demonstrate that SSC,single-fruit weight,fruit longitudinal diameter,fruit equatorial diameter,L*,a*,and b*are significantly and positively correlated with the accumulated temperature.Meanwhile,hardness and titratable acid showed significant negative correlations with the accumulated temperature.Relations between scores of principal components and accumulated temperature conform to the Sigmoidal model.The constructed quantitative maturity model of Korla fragrant pears can quantify the maturity of pears.Research conclusions can provide insight into the harvest periods,evaluate Korla fragrant pears’maturity,and lay a theoretical foundation for quantitative research on fruit maturity. | Shihui Yu Yurong Tang Haipeng Lan Xiaolong Li Hong Zhang Yong Zeng Hao Niu Xiaozhen Jin Yang Liu | 2022 | International Journal of Agricultural and Biological Engineering2022，15，4： | 0 |
| 13 | Morphological, physiological and molecular characteristics of the seedless 'Hongjiangcheng' sweet orange显示文摘Seedless citrus has become one of the breeding goals due to its high edible ratio and convenience in fresh consumption and processing.In this study, the ‘Hongjiangcheng' sweet orange(WT) and its seedless mutant(MT) after cobalt-60 radiation were selected to study the formation metabolism of citrus seedless phenotype. Compared with WT, the MT had altered primary metabolite contents, as indicated by GC-MS analysis. The mature pollen of the MT was mostly distorted and shrunken, and the orange mutant exhibited significantly lower fertility than the WT. Through pollination experiments and paraffin sectioning of the MT, we observed self-compatibility during pollen tube germination in situ, in combination with the absence of natural parthenocarpy and arrested zygotic embryo development at the fourth week after pollination. From transcriptomic analyses of ovules in the fourth week, 815 differentially expressed genes(DEGs) were identified.Furthermore, according to the annotation of gene function and qRT-PCR analysis, Cs4g10930, Cs5g21900 and orange1.1t02243 were identified as candidate genes that may govern the mechanism of seedlessness. Finally, Agrobacterium-mediated transformation verified that the overexpression of Cs4g10930 and Cs5g21900 in Newhall navel orange calli inhibited embryoid production. This study provides a better understanding of seedless formation in citrus and two key genes that may play an important role in the early selection of seedless lines in citrus breeding programs. | Pei Yin Wenyu Ding Haipeng Zhang Xiao Liu Hongyan Zhang Jiwu Zeng Juan Xu | 2023 | Horticultural Plant Journal2023，9，3： | 0 |
| 14 | Performances of a prototype point-contact germanium detector immersed in liquid nitrogen for light dark matter search显示文摘The CDEX-10 experiment searches for light weakly interacting massive particles, a form of dark matter, at the China Jinping Underground Laboratory, where approximately 10 kg of germanium detectors are arranged in an array and immersed in liquid nitrogen. Herein, we report on the experimental apparatus, detector characterization, and spectrum analysis of one prototype detector. Owing to the higher rise-time resolution of the CDEX-10 prototype detector as compared with CDEX-1 B, we identified the origin of an observed category of extremely fast events. For data analysis of the CDEX-10 prototype detector, we introduced and applied an improved bulk/surface event discrimination method. The results of the new method were compared to those of the CDEX-1 B spectrum. Both sets of results showed good consistency in the 0-12 ke Vee energy range, except for the 8.0 keV K-shell X-ray peak from the external copper. | Hao Jiang LiTao Yang Qian Yue KeJun Kang JianPing Cheng YuanJing Li Henry Tsz-King Wong M.A?artio?lu HaiPeng An JianPing Chang JingHan Chen YunHua Chen Zhi Deng Qiang Du Hui Gong Li He Jin Wei Hu QingDong Hu HanXiong Huang LiPing Jia HauBin Li Hong Li Jian Min Li Jin Li Xia Li XueQian Li YuLan Li Bin Liao FongKay Lin ShinTed Lin ShuKui Liu YanDong Liu YuanYuan Liu ZhongZhi Liu Hao Ma JingLu Ma Hui Pan Jie Ren XiChao Ruan B.Sevda Vivek Sharma ManBin Shen Lakhwinder Singh Monoj Kumar Singh TianXi Sun ChangJian Tang WeiYou Tang Yang Tian GuangFu Wang JiMin Wang Li Wang Qing Wang Yi Wang ShiYong Wu YuCheng Wu HaoYang Xing Yin Xu Tao Xue SongWei Yang Nan Yi ChunXu Yu HaiJun Yu JianFeng Yue XiongHui Zeng Ming Zeng Zhi Zeng FengShou Zhang YunHua Zhang MingGang Zhao JiFang Zhou ZuYing Zhou JingJun Zhu ZhongHua Zhu | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，3： | 0 |
| 15 | Enhancement and recovery of photoluminescence and stability by multifunctional etching ligands treatment for perovskite nanocrystals显示文摘Perovskite nanocrystals(PNCs)have recently become promising optoelectronic materials due to their excellent photophysical properties.However,the highly dynamic binding state between ligands and the surface of PNCs has severely restricted their luminescent properties and stabilities.In this work,1,3-bisbenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid(cycle acid,CA)is introduced as both an etchant and a ligand upon post-synthetic surface treatment of PNCs.By removing the imperfect octahedrons[Pb X_(6)]^(4-)and passivating the surface defects synergistically,this treatment improves photoluminescence quantum yields from 76%to 95%and enhances the stability of PNCs against polar solvent,moisture,heat,and illumination.Meanwhile,CA can effectively and instantly recover the luminescence emission for aged PNCs.As a result,the CA-Cs Pb Br_(3)PNCs and CA-Cs Pb IxBr_(3-x)PNCs are applied as color-converting layers on a blue LED chip for warm white light-emitting diodes(WLEDs)with a color coordinate of(0.41,0.40).Importantly,the CA-based WLED device exhibits superior stability in operational conditions. | Yang Zhao Haipeng Zeng Xueqing Cai Yingshan Zhou Yangming Jiang Xin Zheng Lin Li Shujing Zhang Long Luo Weixi Li Xiaoru Zhang Ranran Liu Wenxi Liang Rui Guo Xiong Li | 2023 | Journal of Energy Chemistry2023，，1： | 0 |
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