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468篇 您的检索式:作者名="Hamilton J C"
    题名 作者 年代 出处 被引量
1Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease显示文摘The onset of alcoholic liver disease (ALD) is initiated by different cell types in the liver and a number of different factors including: products derived from ethanol-induced inflammation, ethanol metabolites, and the indirect reactions from those metabolites. Ethanol oxidation results in the production of metabolites that have been shown to bind and form protein adducts, and to increase inflammatory, fibrotic and cirrhotic responses. Lipopolysaccharide (LPS) has many deleterious effects and plays a significant role in a number of disease processes by increasing inflammatory cytokine release. In ALD, LPS is thought to be derived from a breakdown in the intestinal wall enabling LPS from resident gut bacterial cell walls to leak into the blood stream. The ability of adducts and LPS to independently stimulate the various cells of the liver provides for a two-hit mechanism by which various biological responses are induced and result in liver injury. Therefore, the purpose of this article is to evaluate the effects of a two-hit combination of ethanol metabolites and LPS on the cells of the liver to increase inflamma-tion and fi brosis, and play a role in the development and/or progression of ALD.Courtney S Schaffert Michael J Duryee Carlos D Hunter Bartlett C Hamilton 3rd Amy L DeVeney Mary M Huerter Lynell W Klassen Geoffrey M Thiele 2009World Journal of Gastroenterology2009,15,10:20
2An integrated anal ytical approach for determining the origin of solid bitumens in the McArthur Basin,Northern Australia显示文摘George S C Llorca S M Hamilton P J 1994Org Geochem1994,21,:1
3Phytoremediation of soil contaminated with low concentrations of radionuclides显示文摘Entry J A Vance N C Hamilton M A 1996Water Air Soil Pollution1996,88,:1
4C-2 neurec-tomy during atlantoaxial instrumented fusion in the elderly: patient satisfaction and surgical outcome 显示文摘Hamilton D K Smith J S Sansur C A 2011J Neurosurg Spine2011,15,1:1
5Effect of pH on glucose and starch fermentation in batch and sequenced batch mode with a recently isolated strain of hydrogen-producing Clostridium butyricum CWBI1009 显示文摘Masset J Hiligsmann S Hamilton C 2010International Journal of Hydrogen Energy2010,35,8:1
6Evidence for a male-produced sex pheromone in the western flower thrips Frankliniella occidentals显示文摘Kirk W D J Hamilton J G C 0,,01:1
7A species of small antisense RNA in post transcriptional gene silencing in plants显示文摘HAMILTON A J BAULCOMBE D C 1999Science1999,286,5441:1
8The nitrogen budget of a pine forest under free air CO2 enrichment显示文摘 Delucia E H Hamilton J G 2002Oecologia2002,132,:1
9An investigation of the route and progression of encephalitozoon cuniculi infection in adult rabbits显示文摘Cox J C Hamilton R C Attwood H D 1979J Protozool1979,26,1:1
10Efficient attribute-oriented generalization for knowledge discovery from large databases 显示文摘Carter C L Hamilton H J 1998IEEE Transactions on Knowledge and Data Engineering1998,10,2:1
11Directed evolution of ionizing radiation resistance in Escherichia coli 显示文摘Harris D R Pollock S V Wood E A Goiffon R J Klingele A J Cabot E L Schackwitz W Martin J Eggington J Durfee T J Middle C M Norton J E Popelars M C Li H Klugman S A Hamilton L L Bane L B Pennacchio L A Albert T J Perna N T Cox M M Battista J R 2009Journal of Bacteriology2009,191,16:1
12The production and emission of nitrous oxide from headwater streams in the midwestern United States显示文摘Beaulieu J J Arango C P Hamilton S K 2008Global Change Biology2008,14,4:1
13Organic polymer thin-film transistor photosensors 显示文摘Hamilton M C Kanicki J 2004IEEE J Sel Top Quantum Electron2004,10,4:1
14Effect of nitroglycerin ointment on bone density and strength in postmenopausal women: a randomized trial显示文摘Jamal SA Hamilton C J Eastell R 2011JAMA2011,305,8:1
15Acousticand other physical properties of shallow-water sediments offSan Diego显示文摘HAMILTON E L MENARD H W SHIPEX C J 1956 1956The Journal of the Acoustical Society ofAmerica1956,28,:1
16Use of a ramp velocity test to measure critical swimming speed in Rainbow trout (Oncorhynchus mykiss) 显示文摘Jain K E Hamilton J C Farrell A P 1997Comparative Biochemistry Physiology1997,117,:1
17A species of small antisens RNA in post transcriptional gene silencing in plants显示文摘Hamilton A J Baulcombe D C 1999Science1999,286,5441:1
18Continental-scale magmatic carbon dioxide seepage recorded by dawsonite in the Bowen-Gunnedah-Sydney basin system,eastern Australia 显示文摘Baker J C Bai G P Hamilton P J 1995Journal of Sedimentary Research1995,65,3:1
19Excess of nonparental bands in offspring from known pedigrees assayed using RAPD PCR显示文摘Reidy M F Hamilton W J Aquadro C F 1992Nucleic Acids Res1992,20,:1
20Dislocation nucleation and defect structure during surface indentation 显示文摘Kelchner C L Plimpton S J Hamilton J C 1998Phys Rev B1998,58,11:1
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