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| 1 | Nationwide trends and predictors of inpatient mortality in 83884 transjugular intrahepatic portosystemic shunt显示文摘AIM: To evaluate and validate the national trends and predictors of in-patient mortality of transjugular intrahepatic portosystemic shunt(TIPS) in 15 years.METHODS: Using the National Inpatient Sample which is a part of Health Cost and Utilization Project, we identified a discharge-weighted national estimate of 83884 TIPS procedures performed in the United States from 1998 to 2012 using international classification of diseases-9 procedural code 39.1. The demographic, hospital and co-morbility data were analyzed using a multivariant analysis. Using multi-nominal logistic regression analysis, we determined predictive factors related to increases in-hospital mortality. Comorbidity measures are in accordance to the Comorbidity Software designed by the Agency for Healthcare Research and Quality.RESULTS: Overall, 12.3% of patients died during hospitalization with downward trend in-hospitalmortality with the mean length of stay of 10.8 ± 13.1 d. Notable, African American patients(OR = 1.809 vs Caucasian patients, P < 0.001), transferred patients(OR = 1.347 vs non-transferred, P < 0.001), emergency admissions(OR = 3.032 vs elective cases, P < 0.001), patients in the Northeast region(OR = 1.449 vs West, P < 0.001) had significantly higher odds of inhospital mortality. Number of diagnoses and number of procedures showed positive correlations with in-hospital death(OR = 1.249 per one increase in number of procedures). Patients diagnosed with acute respiratory failure(OR = 8.246), acute kidney failure(OR = 4.359), hepatic encephalopathy(OR = 2.217) and esophageal variceal bleeding(OR = 2.187) were at considerably higher odds of in-hospital death compared with ascites(OR = 0.136, P < 0.001). Comorbidity measures with the highest odds of in-hospital death were fluid and electrolyte disorders(OR = 2.823), coagulopathy(OR = 2.016), and lymphoma(OR = 1.842).CONCLUSION: The overall mortality of the TIPS procedure is steadily decreasing, though the length of stay has remained relatively constant. Specific patient ethnicity, location, transfer status, primary diagnosis and comorbidities correlate with increased odds of TIPS in-hospital death. | Edward Wolfgang Lee Andrew Kuei Sammy Saab Ronald W Busuttil Francisco Durazo Steven-Huy Han Mohamed M El-Kabany Justin P Mc Williams Stephen T Kee | 2016 | World Journal of Gastroenterology2016，22，25： | 7 |
| 2 | Computation of flow through the oesophagogastric junction显示文摘Whilst methods exist to indirectly measure the effects of increased flow or gastro-oesophageal refluxing, they cannot quantitatively measure the amount of acid travelling back up into the oesophagus during reflux, nor can they indicate the flow rate through the oesophagogastric junction (OGJ). Since OGJ dysfunction affects flow it seems most appropriate to describe the geometry of the OGJ and its effect on the flow. A device known as the functional lumen imaging probe (FLIP) has been shown to reliably measure the geometry of and pressure changes in the OGJ. FLIP cannot directly measure flow but the data gathered from the probe can be used to model flow through the junction by using computational flow dynamics (CFD). CFD uses a set of equations known as the Navier-Stokes equations to predict flow patterns and is a technique widely used in engineering. These equations are complex and require appropriate assumptions to provide simplifications before useful data can be obtained. With the assumption that the cross-sectional areas obtained via FLIP are circular, the radii of these circles can be obtained. A cubic interpolation scheme can then be applied to give a high-resolution geometry for the OGJ. In the case of modelling a reflux scenario, it can be seen that at the narrowest section a jet of fluid squirts into the oesophagus at a higher velocity than the fluid surrounding it. This jet has a maximum velocity of almost 2 ms-1 that occurs where the OGJ is at its narrowest. This simple prediction of acid ‘squirting’ into the oesophagusillustrates how the use of numerical methods can be used to develop a better understanding of the OGJ. This initial work using CFD shows some considerable promise for the future. | Barry P McMahon Karl D Odie Kenneth W Moloney Hans Gregersen | 2007 | World Journal of Gastroenterology2007，13，9： | 2 |
| 3 | Data mining:an overview from a data base perspective显示文摘 | Chen M S Han J W Yu P S | 1996 | IEEE Transactions on Knowledge and Data Engineering1996，8，6： | 1 |
| 4 | Predictive and prognostic impact of epidermal growth factor receptor mutation in non-small-cell lung cancer patients treated with Gefitinib显示文摘 | HAN S W KIM T Y HWANG P G | 2005 | J Clin Oncol2005，23，11： | 1 |
| 5 | 显示文摘 | Li K Wu P P Han Z W | 2002 | Polymer2002，43，14： | 1 |
| 6 | Identification of eight genes encoding chemokine-like factor super family member 1-8(CKLFSF1-8) by in silico cloning and experimental validation显示文摘 | Han W Ding P Xu M | 2003 | Genomics2003，81，： | 1 |
| 7 | A method for color image seg- mentation based on color similarity coefficient显示文摘 | Han X W Yang Z Li Y P | 2004 | Journal of Shenyang University2004，16，6： | 1 |
| 8 | Total factor carbon e-mission performance; a malmquist index analysis显示文摘 | ZHOU P ANG B W HAN J Y | 2010 | En-ergy Economics2010，32，1： | 1 |
| 9 | Clinical outcomes after lumbar discectomy for sciatica: the effects of fragment type and anular competence显示文摘 | Carragee E J Han M Y Suen P W | 2003 | J Bone Joint Surg Am2003，85，1： | 1 |
| 10 | Total factor carbon emission performance: a malmquist index analysis显示文摘 | Zhou P Ang B W Han J Y | 2010 | Energy Economics2010，32，1： | 1 |
| 11 | Design of high power permanent magnet motor with segment rectangular copper wire and closed slot opening on electric vehicles显示文摘 | Choi J H Chtm Y D Han P W | 2010 | IEEE Transactions on Magnetics2010，46，6： | 1 |
| 12 | Total Factor Carbon Emission Performance: A Malmquist Index Analysis 显示文摘 | Zhou P Ang ]3 W Han J Y | 2010 | Energy Economics2010，32，1： | 1 |
| 13 | 查看详情显示文摘 | Zhang J P Yang H P Han K L Deng W Q He G Z Lou N Q | | 0，，： | 1 |
| 14 | Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental valida- tion显示文摘 | Han W Ding P Xu M | 2003 | Genomics2003，81，： | 1 |
| 15 | Controlling eutrophication: Nitrogen and phosphorus显示文摘 | Daniel J C Hans W P Robert W H | 2009 | Science2009，323，20： | 1 |
| 16 | Total Factor Carbon Emission Per-formance :A Malmquist Index Analysis 显示文摘 | Zhou P Ang B W Han J Y | 2010 | Enei^y Economics2010，32，1： | 1 |
| 17 | Palladium-catalyzed dehydrogenative cross-couplings of benzazoles with azoles显示文摘 | Han W Mayer P Ofial A R | 2011 | Angew Chem Int Ed2011，50，9： | 1 |
| 18 | XPS and XRD investigation of Co/Pd/TiO2catalysts by different preparation methods 显示文摘 | Huang W Zuo Z J Han P D | 2009 | Journal of Electron Spectroscopy and Related Phenomena2009，173，23： | 1 |
| 19 | Data Mining: An Overviewfrom a Data base Perspective 显示文摘 | Chen M S Han J W Yu P S | 1996 | IEKK Transactions on Knowledge and Data Engineering1996，8，86： | 1 |
| 20 | The Study of Intelligent Vehicle Navigation Path Based on Behavior Coordination of Particle Swarm 显示文摘 | HAN G N FU W P WANG W | 2016 | Computational Intelligence and Neuroseienee2016，，65： | 1 |
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