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| 1 | Near-infrared fluorescence sentinel lymph node detection in gastric cancer: A pilot study显示文摘AIM: To investigate feasibility and accuracy of nearinfrared fluorescence imaging using indocyanine green: nanocolloid for sentinel lymph node(SLN) detection in gastric cancer.METHODS: A prospective, single-institution, phaseI feasibility trial was conducted. Patients suffering from gastric cancer and planned for gastrectomy were included. During surgery, a subserosal injection of 1.6 m L ICG:Nanocoll was administered around the tumor. NIR fluorescence imaging of the abdominal cavity was performed using the Mini-FLARE? NIR fluorescence imaging system. Lymphatic pathways and SLNs were visualized. Of every detected SLN, the corresponding lymph node station, signal-to-background ratio and histopathological diagnosis was determined. Patients underwent standard-of-care gastrectomy. Detected SLNs outside the standard dissection planes were also resected and evaluated.RESULTS: Twenty-six patients were enrolled. Four patients were excluded because distant metastases were found during surgery or due to technical failure of the injection. In 21 of the remaining 22 patients, at least 1 SLN was detected by NIR Fluorescence imaging(mean 3.1 SLNs; range 1-6). In 8 of the 21 patients, tumor-positive LNs were found. Overall accuracy of the technique was 90%(70%-99%; 95%CI), which decreased by higher p T-stage(100%, 100%, 100%, 90%, 0% for respectively Tx, T1, T2, T3, T4 tumors). All NIR-negative SLNs were completely effaced by tumor. Mean fluorescence signal-to-background ratio of SLNs was 4.4(range 1.4-19.8). In 8 of the 21 patients, SLNs outside the standard resection plane were identified, that contained malignant cells in 2 patients.CONCLUSION: This study shows successful use of ICG:Nanocoll as lymphatic tracer for SLN detection in gastric cancer. Moreover, tumor-containing LNs outside the standard dissection planes were identified. | Quirijn RJG Tummers Leonora SF Boogerd Wobbe O de Steur Floris PR Verbeek Martin C Boonstra Henricus JM Handgraaf John V Frangioni Cornelis JH van de Velde Henk H Hartgrink Alexander L Vahrmeijer | 2016 | World Journal of Gastroenterology2016，22，13： | 9 |
| 2 | First Experience in Humans Using Adipose Tissue–Derived Regenerative Cells in the Treatment of Patients With ST-Segment Elevation Myocardial Infarction显示文摘 | Jaco H. Houtgraaf Wijnand K. den Dekker Bas M. van Dalen Tirza Springeling Renate de Jong Robert J. van Geuns Marcel L. Geleijnse Francisco Fernandez-Aviles Felix Zijlsta Patrick W. Serruys Henricus J. Duckers | 2012 | Journal of the American College of Cardiology2012，，5： | 1 |
| 3 | A dedicated applicator for light delivery and monitoring of PDT of intra-anal intraepithelial neoplasia显示文摘 | Bastiaan Kruijt Eric M. van der Snoek Henricus J.C.M. Sterenborg Arjen Amelink Dominic J. Robinson | 2010 | Photodiagnosis and Photodynamic Therapy2010，，1： | 1 |
| 4 | Extrapulmonary Small Cell Carcinoma显示文摘 | Henricus F.M. van der Heijden Yvonne F. Heijdra | 2005 | Southern Medical Journal2005，，3： | 1 |
| 5 | CCBE1 Is Essential for Mammalian Lymphatic Vascular Development and Enhances the Lymphangiogenic Effect of Vascular Endothelial Growth Factor-C In Vivo显示文摘 | Frank L. Bos Maresa Caunt Josi Peterson-Maduro Lara Planas-Paz Joe Kowalski Terhi Karpanen Andreas van Impel Raymond Tong James A. Ernst Jeroen Korving Johan H. van Es Eckhard Lammert Henricus J. Duckers Stefan Schulte-Merker | 2011 | Circulation Research2011，，5： | 1 |
| 6 | Correction of patient results for Beckman Coulter LX-20 assays affected by interference due to hemoglobin, bilirubin or lipids: a practical approach显示文摘 | Henricus J. Vermeer Gerard Steen André J.M. Naus Berrie Goevaerts Pauline T. Agricola Christian H.H. Schoenmakers | 2007 | Clinical Chemical Laboratory Medicine2007，，1： | 1 |
| 7 | Detection of theβ2-toxin gene of clostridium perfringens in diarrhoeic piglets in the Netherlands and Switzerland显示文摘 | Henricus L B Mklaasen Marc J C | 1999 | FEMS Immunology and Medical Microbiology1999，24，： | 1 |
| 8 | Cervical osteotomy in ankylosing spondylitis:evaluation of new developments显示文摘 | Langeloo DD Henricus LJ Paul WP | 2006 | Eur Spine2006，15，4： | 1 |
| 9 | Nonmuscle Myosin Heavy Chain IIA Mutation Predicts Severity and Progression of Sensorineural Hearing Loss in Patients With MYH9-Related Disease显示文摘 | Eva J. J. Verver Vedat Topsakal Henricus P. M. Kunst Patrick L. M. Huygen Paula G. Heller Nuria Pujol-Moix Anna Savoia Marco Benazzo Tiziana Fierro Wilko Grolman Paolo Gresele Alessandro Pecci | 2016 | Ear and Hearing2016，，： | 1 |
| 10 | Automated Processing of Serum Indices Used for Interference Detection by the Laboratory Information System 显示文摘 | Henricus J | 2005 | Clin Chem2005，51，1： | 1 |
| 11 | Exttracorporesl perfusion for the treatment of acute liver failure显示文摘 | Henricus BAC Stockman MD Coen A | 1999 | Ann Surg1999，231，4： | 1 |
| 12 | Tidal breathing analysis as a measure of airway obstruction in children three years of age and older显示文摘 | Cornelis K Van der Ent Henricus J L | 1996 | Am J RespirCrit Care Med1996，153，： | 1 |
| 13 | Differences in metabolism between adeno- and squamous cell non-small cell lung carcinomas: Spatial distribution and prognostic value of GLUT1 and MCT4显示文摘 | Tineke W.H. Meijer Olga C.J. Schuurbiers Johannes H.A.M. Kaanders Monika G. Looijen-Salamon Lioe-Fee de Geus-Oei Ad F.T.M. Verhagen Jasper Lok Henricus F.M. van der Heijden Saskia E. Rademakers Paul N. Span Johan Bussink | 2011 | Lung Cancer2011，，3： | 1 |
| 14 | Detection of the β2 toxin gene of Clostridium perfringens in diarrhoeic pig- lets in the Netherlands and Switzerland显示文摘 | Henricus L Klaasen B M Molkenboer J C H | 1999 | FEMS Immunology and Medical Microbiology1999，24，： | 1 |
| 15 | Oxidative Stress and Pathological Changes After Coronary Artery Interventions显示文摘 | Rio P. Juni Henricus J. Duckers Paul M. Vanhoutte Renu Virmani An L. Moens | 2013 | Journal of the American College of Cardiology2013，，14： | 1 |
| 16 | Fatty acid profiles ofalgae mark the development and composition of harpacticoid cope-pods显示文摘 | CARAMUJO M J HENRICUS T S B WIM A | 2008 | Freshwater Biology2008，53，1： | 1 |
| 17 | Hospital specific as- pects predominantly determine primary failure of hemodialysis arte- riovenous fistulas 显示文摘 | Henricus JIAM Jbregts H Michiel LB | 2007 | Vas G $urg2007，45，5： | 1 |
| 18 | Tidal breathing analysis as a measure of airway obstruction in children three years of age and older显示文摘 | Cornelis K Vander Ent Henricus JL | 1996 | Am J Respir Crit Care Med1996，153，： | 1 |
| 19 | Serotonin uptake by blood platelets of acute schizophrenic patients显示文摘 | Ilan Modai Avner Rotman Hanan Munitz Shmuel Tjano Henricus Wijsenbeek | 1979 | Psychopharmacology1979，，2： | 1 |
| 20 | Surgical treatment of a rare complication after endoscopic stent placement for anastomotic leakage after esophageal resection显示文摘The best approach to achieve cure in esophageal cancer is a combination of chemo-radiation and surgery. However, complications occur in half of patients. The current report, reports a rare but severe complication: Complete obstruction of the esophagus, induced by preoperative chemo-radiation therapy. Normally, strictures are treated by repeated dilatations, however, in case of complete obstruction, the perforation rate of standard blind anterograde wire access and dilation is severely increased. In order to minimize the risk of perforations, the rendezvous technique was introduced. This technique involves an anterograde approach in combination with a retrograde approach in order to open and dilatate the esophagus. While technical success rates between 83% and 100% have been reported in literature, data on clinical outcomes are scarcer. The limited amount of studies available claim that success was achieved in almost half of patients. The patient in our case currently has an oral diet without restrictions and rates his quality of life with a VAS-score ten out of ten. | Marjan Klinkert Mechteld C de Jong Meindert N Sosef Annick B van Nunen Henricus J Belgers | 2017 | World Journal of Surgical Procedures2017，7，1： | 1 |
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