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18篇 您的检索式:作者名="Ian Wright"
    题名 作者 年代 出处 被引量
1Progress in carbon dioxide separation and capture: A review显示文摘这篇文章考察在 CO2 分离和俘获研究和工程取得的进步。各种各样的技术例如吸收,吸附,和膜分离,彻底地被讨论。象化学循环的燃烧和基于水合物的分离那样的新概念也简短被介绍。未来方向被建议。隐遁方法海洋授精和矿物质碳酸饱和技术例如造林,也被盖住。地下的注射和直接海洋垃圾场没被盖住。Hongqun Yang Zhenghe Xu Maohong Fan Rajender Gupta Rachid B Slimane Alan E Bland Ian Wright 2008Journal of Environmental Sciences2008,20,1:89
2肺癌全基因组测序显示文摘肺癌是全球肿瘤发病率和病死率的主因,且预后很差。加强对肿瘤生物学的认识对肺癌研究至关重要。被誉为'下一代测序技术'的NGS技术(next-generation sequencing)是一种针对全基因组鉴定的有力工具,可以对致癌体细胞突变进行全面检测。大多数的NGS技术是基于平台特异性DNA文库进行多重聚合酶链反应(polymerase chain reaction,PCR),从而对目的基因扩增后测序。这种技术适用于高通量测序,可以检测出肿瘤中出现的全部基因组变异。缺点是这种技术需要在时间、实验设备、计算机数据分析、生物信息技术等各方面的大量投入。NGS技术已广泛应用于全基因组、外显子组、转录组和表观基因组的研究中,为肺癌研究和医疗模式带来改变。这项新技术的开展将转变当前对致癌信号通路的认识,可为癌症诊疗提供新的分子靶点。肺癌体细胞突变已有NGS技术的分析报道,但大规模基因组研究仍在进行中。个体化治疗策略将改善那些潜在获益患者的治疗方式,避免'无辜'患者受无效治疗带来的高额费用和不良反应。NGS的组织化、计算机化和生物信息化技术推动了科技的进步,同时,患者知情权和数据发布的相关伦理问题也浮现出来。信号通路中,驱动基因(driver gene)突变和传递基因(passenger gene)突变的区别,需要对测序结果进行细致解读。解读准确与否取决于DNA提取的样本类型、样本处理技术和样本含量。肿瘤异质性也会降低肿瘤基因突变的检测效能。NGS技术将推动对肿瘤基因突变的基础和临床研究,而且,也可应用于单细胞和游离的循环DNA,未来还将用于从体液和肿瘤亚群中获取的DNA样本。如果能进一步降低费用、提高检验速度和精度,NGS技术无疑将会成为肺癌研究的绝佳选择。Marissa Daniels Felicia Goh Casey M. Wright Krishna B. Sriram Vandana Relan Belinda E. Clarke Edwina E. Duhig Rayleen V. Bowman Ian A Yang Kwun M. Fong 孙岚 何建行 2013国际病理科学与临床杂志2013,33,4:2
3The worldwide leaf economics spectrum显示文摘Wright Ian J Reich Peter B Westoby Mark 2004Nature2004,428,6985:1
4PLANT ECOLOGICAL STRATEGIES: Some Leading Dimensions of Variation Between Species显示文摘Mark Westoby Daniel S. Falster Angela T. Moles Peter A. Vesk Ian J. Wright 2002Annual Review of Ecology and Systematics2002,,:1
5Inhomogeneous substrate analysis using EM300 backscatter imagery显示文摘Yves Le Gonidec Geoffroy Lamarche Ian C. Wright 2003Marine Geophysical Researches (-)2003,,3:1
6Reich Photosynthetic differences contribute to competitive advantage of evergreen angiosperm trees over evergreen conifers in productive habitats显示文摘Christopher H Lusk Ian Wright Peter B 2003New Phytologist2003,160,:1
7Land-plant ecology on the basis of functional traits显示文摘Mark Westoby Ian J. Wright 2006Trends in Ecology & Evolution2006,,5:1
8The leaf size-twig size spectrum and its relationship to other important spectra of variation among species显示文摘Westoby M Wright Ian J 2003Oecologia2003,135,4:1
9PLANT ECOLOGICAL STRATEGIES: Some Leading Dimensions of Variation Between Species显示文摘Mark Westoby Daniel S. Falster Angela T. Moles Peter A. Vesk Ian J. Wright 2002Annual Review of Ecology and Systematics2002,,:1
10A Comprehensive Mutation Analysis of RP2 and RPGR in a North American Cohort of Families with X-Linked Retinitis Pigmentosa显示文摘Debra K. Breuer Beverly M. Yashar Elena Filippova Suja Hiriyanna Robert H. Lyons Alan J. Mears Bersabell Asaye Ceren Acar Raf Vervoort Alan F. Wright Maria A. Musarella Patricia Wheeler Ian MacDonald Alessandro Iannaccone David Birch Dennis R. Hoffman Ger 2002The American Journal of Human Genetics2002,,6:1
11Common pathogenic mechanisms and pathways in the development of COPD and lung cancer显示文摘Ian A Yang Vandana Relan Casey M Wright Morgan R Davidson Krishna B Sriram Santiyagu M Savarimuthu Francis Belinda E Clarke Edwina E Duhig Rayleen V Bowman Kwun M Fong 2011Expert Opinion on Therapeutic Targets2011,,4:1
12Influence of Oxide Growth and Metal Creep on Strain Development in the Steam-Side Oxide in Boiler Tubes显示文摘Adrian S. Sabau Ian G. Wright 2010Oxidation of Metals2010,,5:1
13Current systemic management of metastatic renal cell carcinoma – first line and second line therapy显示文摘Ian Wright Anil Kapoor 2011Current Opinion in Supportive and Palliative2011,,3:1
14The execution kernel of rc++:Rete*,a faster rete with treat as special case显示文摘Ian Wright James Marshall 2003International Journalof Intelligent Games and Simulation February2003,2,1:1
15‘Carbon footprinting’: towards a universally accepted definition显示文摘Laurence A Wright Simon Kemp Ian Williams 2011Carbon Management2011,,:1
16Differential scanning calorimetric studies of muscle and its constituent proteins显示文摘David J Wright Ian B Leach 1977Journal of the Science of Food and Agriculture1977,28,6:1
17A Review of the Oxidation Behaviour of Structural Alloys in Steam 显示文摘WRIGHT IAN G DOOLEY R B 2010International Materials Reviews2010,55,3:1
18塔塔需备总资本豢养“虎豹”显示文摘经济状况和未来的排放要求可能对这两个品牌不利,塔塔应为此做好准备,并具有足够的资本,才能安全渡过这场经济风暴。Ian Fletcher Rebecca Wright 2008汽车与配件2008,,15:0
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