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| 1 | Visual impairment in Parkinson's disease treated with amantadine: case report and review of the literature 显示文摘 | Kubo S Iwatake A Ebihara N | 2008 | Parkinsonism Relat Disord2008，14，2： | 1 |
| 2 | Cellulose nanofiber-reinforced polylacitic acid 显示文摘 | IWATAKE A NOGI M YANO H | 2008 | Composites Science and Technology2008，68，9： | 1 |
| 3 | A case report of acquired ehoanal atresia显示文摘 | MIHO H KATO I IWATAKE H | 1996 | Acta Otolaryngol Suppl1996，522，： | 1 |
| 4 | Cellulose Nanofiber-rein- forced Polylactic Acid显示文摘 | IWATAKE A NOGI M YANO H | 2008 | Composites Science and Technolo- gy2008，68，9： | 1 |
| 5 | A case of relapsing polychondritis involving placement of an expandable metallic stent显示文摘 | Nobukiyo S Iwatake H Watanabe S | 2003 | Anris Nasus Larynx2003，30，： | 1 |
| 6 | ARTS: Accelerated Ray-Tracing System 显示文摘 | TanakaT IwataK | 1985 | IEEE CG&A1985，5，： | 1 |
| 7 | NOX1/NADPHoxi-daseisinvolvedinendotoxin-inducedcardiomyocyteapoptosis显示文摘 | MatsunoK IwataK MatsumotoM etal | 2012 | FreeRadicBiolMed2012，53，9： | 1 |
| 8 | Coupling of ocean bottom seismometers to soft bottoms 显示文摘 | SUTTON G H DUENNEBIER F K IWATAKE B | 1981 | Marine Geophysical Researches1981，，5： | 1 |
| 9 | AModelingandSimulationArechitectureforVirtualManufacturingSystems显示文摘 | IWATAK | 1995 | AnnalsoftheCIRP1995，44，： | 1 |
| 10 | Longtermeffectofepalrestatoncardiacautonomicneuropathyinsubjectswithnoninsulindependentdiabetesmellitus显示文摘 | IkedaT IwataK TanakaY | 2010 | DiabetesResClinPraex2010，43，3： | 1 |
| 11 | New highly heat-resistantpolymers containing silicon : poiy(silyleneethynylenephenylenee-thynylene) s显示文摘 | Itoh M Inoue K IwataK 过 a/ | 1997 | Macromolecules1997，30，： | 1 |
| 12 | Effect of insulin, proinsulin, and amylin on rennin release from perfused ratkidney 显示文摘 | Ikeda T IwataK OchiH | 2001 | Metabolism2001，50，7： | 1 |
| 13 | Comparison of the S/N ratios of low-frequency hydrophones and geophones as a function of ocean depth显示文摘 | BROCHER T M IWATAKE B T GETTBUST JF | 1981 | Bulletin of the Seismological Society of America1981，71，5： | 1 |
| 14 | The management of possible fishbone ingestion显示文摘 | Yoshihiro Akazawa Shoji Watanabe Shigenori Nobukiyo Hiroya Iwatake Yoshitake Seki Tsuyoshi Umehara Kouichiro Tsutsumi Izumi Koizuka | 2004 | Auris Nasus Larynx2004，，4： | 1 |
| 15 | A case of relapsing polychondritis involving placement of an expandable metallic stent显示文摘 | Nobukiyo S Iwatake H Watanabe S | | 0，，： | 1 |
| 16 | Cellulose nanofibre-reinforced polylactic acid 显示文摘 | Iwatake A Nogim Yano H | 2008 | Composites Science and Technology2008，68，9： | 1 |
| 17 | Gene-activated matrix harboring a miR20a-expressing plasmid promotes rat cranial bone augmentation显示文摘Gene-activated matrix(GAM)has a potential usefulness in bone engineering as an alternate strategy for the lasting release of osteogenic proteins but efficient methods to generate non-viral GAM remain to be established.In this study,we investigated whether an atelocollagen-based GAM containing naked-plasmid(p)DNAs encoding microRNA(miR)20a,which may promote osteogenesis in vivo via multiple pathways associated with the osteogenic differentiation of mesenchymal stem/progenitor cells(MSCs),facilitates rat cranial bone augmentation.First,we confirmed the osteoblastic differentiation functions of generated pDNA encoding miR20a(pmiR20a)in vitro,and its transfection regulated the expression of several of target genes,such as Bambi1 and PPARc,in rat bone marrow MSCs and induced the increased expression of BMP4.Then,when GAMs fabricated by mixing 100 ll of 2%bovine atelocollagen,20mg b-TCP granules and 0.5mg(3.3 lg/ll)AcGFP plasmid-vectors encoding miR20a were transplanted to rat cranial bone surface,the promoted vertical bone augmentation was clearly recognized up to 8 weeks after transplantation,as were upregulation of VEGFs and BMP4 expressions at the early stages of transplantation.Thus,GAM-based miR delivery may provide an alternative non-viral approach by improving transgene efficacy via a small sequence that can regulate the multiple pathways. | Rena Shido Yoshinori Sumita Masahito Hara Mayumi Iwatake Shun Narahara Mayumi Umebayashi Kei-ichiro Miura Yukinobu Kodama Izumi Asahina | 2021 | Regenerative Biomaterials2021，8，2： | 0 |
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