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| 1 | ThePsyehological Treatment of Obsessive--Compulsive Disorder显示文摘 | Jonathan S Abramowitz PhD | 2006 | Can JPsychiatry2006,51,: | 1 |
| 2 | Misoprostol reduces indomethacin-induced changes in human small intestinal permeability显示文摘 | Ingvar Bjarnason MD Paul Smethurst MBiol Christopher G. Fenn PhD Carole E. Lee BSc Ian S. Menzies FRCPath A. Jonathan Levi FRCP | 1989 | Digestive Diseases and Sciences1989,,3: | 1 |
| 3 | Rehospitalization rates of chronically schizophrenic patients discharged on a regimen of risperidlane,olanzapine or conventional antipsychotics显示文摘 | Jonathan PHD Pesath MD Zeev MD | 2001 | Am J Psychiatry2001,158,2: | 1 |
| 4 | Rehospitalization rates of chronically schizophrenic patients discharged on a regimen of risperidone,olanzapine,or conventional antipsychotics显示文摘 | Pesath MD Zeev MD | 2001 | Am J Psychiatry2001,158,2: | 1 |
| 5 | The current situation in human pancreatic islet transplantation: problems and prospects显示文摘 | Naoya Kobayashi MD PhD Teru Okitsu MD PhD Jonathan R.T. Lakey PhD Noriaki Tanaka MD PhD | 2004 | Journal of Artificial Organs2004,,1: | 1 |
| 6 | Gastrointestinal Stromal Tumors and Leiomyosarcoma of the Abdomen and Retroperitoneum: A Clinical Comparison显示文摘 | Bryan M. Clary MD Ronald P. DeMatteo MD Jonathan J. Lewis MD Denis Leung PhD Murray F. Brennan MD | 2001 | Annals of Surgical Oncology2001,,4: | 1 |
| 7 | Rehospitalization rates of chronically schizophrenic patients discharged on a regimen of risperi- done,olanzapine Or conventional anti -psychotics 显示文摘 | Jonathan PHD Pesath MD Zeev MD | 2001 | Am J Psychia- try2001,158,: | 1 |
| 8 | Rehospitalization rates of chmically schizophrenic-patients discharged on a regimen of risperidone,olanzapine,or conventional antipsychoties显示文摘 | Pesath MD Zeev MD | 2001 | Am J Psychiatry2001,158,2: | 1 |
| 9 | Rehospitalization rates of chronically schizophrenic patients discharged on a regimen of risperidlane, olanzapine or conventional antipsychotics显示文摘 | Jonathan PHD Pesath MD Zeev MD | 2001 | Am J Psychiatry2001,158,2: | 1 |
| 10 | Gastrointestinal Stromal Tumors and Leiomyosarcoma of the Abdomen and Retroperitoneum: A Clinical Comparison显示文摘 | Bryan M. Clary MD Ronald P. DeMatteo MD Jonathan J. Lewis MD Denis Leung PhD Murray F. Brennan MD | 2001 | Annals of Surgical Oncology2001,,4: | 1 |
| 11 | Inability to detect hepatitis B surface antigen (HBsAg) in the duodenum of HBsAg-positive persons显示文摘 | Dr. S. Victor Feinman MD Barnet Berris MD Jonathan C. Sinclair MD Strathearn Wilson PhD Damiana Wrobel MD | 1981 | Digestive Diseases and Sciences1981,,4: | 1 |
| 12 | 年轻发病2型糖尿病对中青年比马印第安人终末期肾病发病率和死亡率的影响显示文摘背景:年轻发病2型糖尿病患者的长期结局尚未被阐明。目的:在年轻与年长发生糖尿病的比马印第安人中比较糖尿病性终末期肾病(end-stagerenal disease,ESRD)的发病率和死亡率。设计、地点及参试者:于1965~2002年在Arizona比马印第安人中进行人群纵向研究。参试者分为两组:年轻发病2型糖尿病(发病年龄〈20岁)和年长发病2型糖尿病(发病年龄20~55岁)。随访事件和人年按时间依赖方式以每10岁进行分层。终末期肾病的定义为因糖尿病肾病而接受透析治疗或者死于糖尿病肾病。主要观测指标:根据2型糖尿病的发病年龄,计算25至55岁之间糖尿病ESRD的发病率和死亡率。结果:在1856例糖尿病参试者中,96例为年轻发病。校正年龄及性别后,年轻发病2型糖尿病者ESRD的发生率为每1000人年25.0例(95%可信区间[confidence interval,CI],6.7~43.1),年长发病者ESRD的发病率为每10130人年5.4例(95%CI,4.4~6.4)(发病率比,4.6;95%CI,2.2~9.8)。在所有年龄段中,年轻发病参试者的年龄别ESRD发生率均较高。在校正年龄及性别后,年轻发病2型糖尿病参试者的自然原因死亡率为每10130人年15.4例(95%CI,0.2~30.5),年长发病2型糖尿病个体为每10130人年7.3例(95%CI,5.9~8.7)(死亡率比,2.1;95%CI,0.8~5.7)。与无糖尿病的参试者相比,年轻发病2型糖尿病个体的死亡率为前者的3倍(95%CI,1.1~1.8),年长发病2型糖尿病个体的死亡率是其1.4倍(95%CI,1.1~1.8)。在1386例具有所有协变量完整数据的亚组中(从糖尿病发病开始即进行观察),在校正性别、平均动脉压、体重指数(kg/m^2)、血浆葡萄糖浓度、吸烟、降糖药以及降压药后,Cox比例风险模型显示糖尿病发病年龄与ESRD发病率并不相关(风险比,1.0;95%CI,0.9~1.2)。结论:2型糖尿病较早发病与中年时ESRD发病率和死亡率显著升高相关。其主要原因是20岁以下诊断糖尿病的个体在中年时已有较长的糖尿病病程。 | Meda E. Pavkov, MD, PhD Peter H. Bennett, MB, FRCP William C. Knowler, MD, DrPH Jonathan Krakoff, MD Maurice L Sievers, MD Robert G. Nelson, MD, PhD 蔡润策(译) 贾伟平(校) | 2007 | 美国医学会杂志(中文版)2007,26,3: | 1 |
| 13 | High rates of adverse drug events in a highly computerized hospital 显示文摘 | Jonathan R Nebeker MS MD Jennifer M Hoffman Pharm D Ch-arlene R Weir RN PhD | 2005 | Arch Intern Med2005,165,10: | 1 |
| 14 | Rehospital-ization rates of chronically schizophrenic patients dischargedon a regimen of risperidone,olanzapine or conventional anti-Psychotics显示文摘 | Jonathan PHD Pesath MD Zeev MD et a1 | 2001 | Am J Psychiatry2001,158,2: | 1 |
| 15 | Rehospitalization rates of chronically schizophrenic patients discharged on a regimen of risperidone, olanzapine Or conventional anti-psychotics 显示文摘 | Jonathan PHD Pesath MD Zeev MD | 2001 | Am J Psychiatry2001,158,: | 1 |
| 16 | rehospitalization rates of chronically schizophrenic patients discharged on a regimen of rispefidlane, olanzapine or conventional antipsychotics 显示文摘 | Jonathan PHD Pesath MD Zeev MD | 2001 | Am J Psychiatry2001,158,2: | 1 |
| 17 | Nipah virus: Impact, origins, and causes of emergence显示文摘 | Jonathan H. Epstein DVM MPH Hume E. Field PhD MSc MACVS Stephen Luby MD Juliet R.C. Pulliam MS Peter Daszak PhD | 2006 | Current Infectious Disease Reports2006,,1: | 1 |
| 18 | Surgical Resection of Gastrointestinal Stromal Tumors After Treatment with Imatinib显示文摘 | Robert H. I. Andtbacka MD CM Chaan S. Ng MD Courtney L. Scaife MD Janice N. Cormier MD MPH Kelly K. Hunt MD Peter W. T. Pisters MD Raphael E. Pollock MD PhD Robert S. Benjamin MD Michael A. Burgess MD Lei L. Chen MD PhD Jonathan Trent MD Shreyaskumar | 2007 | Annals of Surgical Oncology2007,,1: | 1 |
| 19 | Surgical Resection of Gastrointestinal Stromal Tumors After Treatment with Imatinib显示文摘 | Robert H. I. Andtbacka MD CM Chaan S. Ng MD Courtney L. Scaife MD Janice N. Cormier MD MPH Kelly K. Hunt MD Peter W. T. Pisters MD Raphael E. Pollock MD PhD Robert S. Benjamin MD Michael A. Burgess MD Lei L. Chen MD PhD Jonathan Trent MD Shreyaskumar | 2007 | Annals of Surgical Oncology2007,,1: | 1 |
| 20 | 奥利司他对肥胖青少年体重和机体组分的影响——随机对照试验显示文摘背景:儿童和青少年超重和肥胖正迅速增加。在该人群,单纯行为疗法减肥及维持体重下降的效果有限,但是对药物治疗尚未进行广泛的研究。
目的:确定奥利州他(Orlistat)在青少年体重治疗方面的效果及其安个性。
设计、地点和病例:于美国和加拿大32个中心、539例肥胖青少年(12—16岁;体重指数[body mass index,BMI]在第95百分化之上≥2单位)进行的多ln0、54剧(2000年8月至2002年10月)随机双盲研究。
干预:给予奥利司他(n=357)或安慰剂(n=182)120mg,每口3次,持续1年;加适度低热卡饮食(脂肪占30%)、运动和行为治疗。
主要观察指标:BMI变化;二级指标包括腰围和髋用、体重下降、脂质测量以及机体对口服葡萄糖的血糖和胰岛素反心。
结果:至12周时,两组BMI均有下降;此后,奥利司他组体重维持稳定而安慰剂组则超过基线。研究结束时,奥利司他组BMI下降0.55。而安慰剂组则增加0.31(P=0.001)。与安慰剂组的15.7%相比,奥利司他组26.5%的病例BMI下降≥5%(P=0.005);BMI下降≥10%者分别为4.5%和13.3%(P=0.002)。在研究结束时,奥利司他组体重增加0.53kg,安慰剂组增加3.14kg(P〈0.001)。双能X线吸收测量娃示,这种差异可用脂肪体再的变化解释。奥利司他组腰围下降,安慰剂组腰围上升(-1.33cm比+0.12cm;P〈0.05)。奥利司他组发生轻至中度胃肠道不良事件者为9%-50%,安慰剂组为1%~13%。
结论:与安慰剂比较,奥利司他与饮食、运动和行为改善联合可显著改善肥胖青少年体重的治疗。在这个青少年人群,连续使用奥利司他1年并无重要安全问题,尽管奥利司他组胃肠道不良事件较为常见。 | Jean-Pierre Chanoine, MD, PhD Sarah Hampl, MD, FAAP Craig Jensen, MD Mark Boldrin, MS Jonathan Hauptman, MD 李呈亿(译) | 2006 | 美国医学会杂志(中文版)2006,25,1: | 0 |