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| 1 | C-reactive protein and radiographic findings of lower respiratory tract infection in infants显示文摘AIM To evaluate the association between C-reactive protein(CRP) and radiological evidence of lower respiratory tract infection(LRTI) in infants.METHODS All patients aged less than 4 years who presented with suspected lower respiratory tract infection,who received a peri-presentation chest radiograph and CRP blood measurement over an 18-mo period were included in the study.Age,gender,source of referral,CRP,white cell count,neutrophil count along with the patients' symptoms and radiologist's report were recorded.RESULTS Three hundred and eleven patients met the inclusioncriteria.Abnormal chest radiographs were more common in patients with elevated CRP levels(P < 0.01).Radiologic signs of LRTI were identified in 73.7% of chest radiographs when a patient had a CRP level between 50-99 mg/L.CRP levels were a better predictor of positive chest radiograph findings for those aged greater than I year compared to those 1 year or less.CONCLUSION CRP may be used in patients with suspected LRTI diagnosis to select those who are likely to have positive findings on chest radiograph,thus reducing unnecessary chest radiographs. | Maria Twomey Hannah Fleming Fiachra Moloney Kevin P Murphy Lee Crush Siobhan B O’Neill Oisin Flanagan Karl James Conor Bogue Owen J O’Connor Michael M Maher | 2017 | World Journal of Radiology2017，9，4： | 2 |
| 2 | Intraarterial Adjuvant Chemotherapy after Pancreaticoduodenectomy for Pancreatic Cancer: Significant Reduction in Occurrence of Liver Metastasis显示文摘 | Hans G. Beger Frank Gansauge Markus W. Büchler Karl Heinz Link | 1999 | World Journal of Surgery1999，，9： | 2 |
| 3 | Erythropoietin therapy after out-of-hospital cardiac arrest:A systematic review and meta-analysis显示文摘AIM To assess safety and efficacy of early erythropoietin(Epo) administration in patients with out-of-hospital cardiac arrest(OHCA).METHODS A systematic literature search was performed using PubM ed,MEDLINE,EMBASE,EBSCO,CINAHL,Web of Science and Cochrane databases,of all studies published from the inception through October 10,2016.Inclusion criteria included:(1) Adult humans with OHCA and successful sustained return of spontaneous circulation;and(2) studies including mortality/brain death,acute thrombotic events as their end points.Primary efficacyoutcome was 'brain death or Cerebral Performance Category(CPC) score of 5'.Secondary outcomes were 'CPC score 1,and 2-4','overall thrombotic events' and 'acute coronary stent thrombosis'.RESULTS We analyzed a total of 606 participants(n = 276 received Epo and n = 330 with standard of care alone) who experienced OHCA enrolled in 3 clinical trials.No significant difference was observed between the Epo and no Epo group in brain death or CPC score 5(OR = 0.77;95%CI:0.42-1.39),CPC score 1(OR = 1.16,95%CI:0.82-1.64),and CPC score 2-4(OR = 0.77,95%CI:0.44-1.36).Epo group was associated with increased thrombotic complications(OR = 2.41,95%CI:1.26-4.62) and acute coronary stent thrombosis(OR = 8.16,95%CI:1.39-47.99).No publication bias was observed.CONCLUSION Our study demonstrates no improvement in neurological outcomes and increased incidence of thrombotic events and acute coronary stent thrombosis in OHCA patients who were treated with Epo in addition to standard therapy. | Rahul Chaudhary Jalaj Garg Parasuram Krishnamoorthy Kevin Bliden Neeraj Shah Nayan Agarwal Rahul Gupta Abhishek Sharma Karl B Kern Nainesh C Patel Paul Gurbel | 2017 | World Journal of Cardiology2017，9，12： | 2 |
| 4 | Bcl-2 acts in a proangiogenic signaling pathway through nuclear factor-kappa B and CXC chemokines 显示文摘 | Karl E Warner K Zeitlin B | 2005 | Cancer Res2005，65，： | 1 |
| 5 | Regulation of gult-4 phosphorylation by intracellular calcium in adipocytes 显示文摘 | Reusch JE Njama B Karl E | 1991 | Endocrinology1991，29，6： | 1 |
| 6 | Ethanol and mitotic inhibi tors promote differentiation of trophoblastic cells 显示文摘 | Harvey B Fisher SE | 1996 | Alcohol Clin Exp Res1996，20，7： | 1 |
| 7 | A variable force binder for a draw press显示文摘 | Zhang S L Karl B O | 1998 | Journal of Materials Processing Technology1998，73，： | 1 |
| 8 | 3D visualization of tomographic volume data using the generalized voxel model显示文摘 | Karl H H Michale B Andreas P | 1990 | The Visual Computer1990，6，1： | 1 |
| 9 | Improved pharmacokinetics of recombinant bispecific antibody molecules by fusion to human serum albumin显示文摘 | Muller D Karle A Meissburger B | 2007 | J Biol Chem2007，282，12： | 1 |
| 10 | Excitation-emission matrix fluorescence based determination of carbamate pesticides and polycyclic aromatic hydrocarbons显示文摘 | Renee D J Gary A C Karl S B | 1999 | Analytica Chimica Acta1999，，397： | 1 |
| 11 | Dinitrogen fixa- tion in the worlds oceans显示文摘 | KARL D MICHAELS A BERGMAN B | 2002 | Biogeochemistry2002，57，1： | 1 |
| 12 | Dinitrogen fixa- tion in the world's oceans 显示文摘 | KARL D MICHAELS B BERGMAN D | 2002 | Biogeochemistry2002，57，1： | 1 |
| 13 | Archaeal dominance in the mesopelagic zone of the Pacific Ocean显示文摘 | KARNER M B DEI ONG E F KARL D M | 2001 | Nature2001，409，： | 1 |
| 14 | Archaeal dominance in the mesopelagic zone of the Pacific Ocean显示文摘 | KARNER M B DELONG E F KARL D M | 2001 | Nature2001，409，： | 1 |
| 15 | Promising practices in understaing andTreating child neglect 显示文摘 | Marianne B Renae C Karl D | 2003 | Child and Family Soc Work2003，8，1： | 1 |
| 16 | Acomparative study of ASOS And USCRN temperature measurements显示文摘 | Sun B Baker C B Karl T R | 2005 | J Atmos Oceanic Technol2005，22，： | 1 |
| 17 | Community genomics among stratified microbial assemblages in the ocean's interior显示文摘 | DeLong E F Preston C M Mincer T Rich V Hallam S J Frigaard N U Martinez A Sullivan M B Edwards R Brito B R Chisholm S W Karl D M | | 0，，5760： | 1 |
| 18 | Progress report: A randomized multicenter European stydy comparing adjuvant radiotherapy, 6 Mo chemotherapy, and combination therapy vs No-adjuvant treatment in resectable pancreatic cancer (ESPAC-1)显示文摘 | John P. Neoptolemos Pat Baker Hans Beger Karl Link Paolo Pederzoli Claudio Bassi Christos Dervenis Helmut Friess Markus Büchler | 1997 | International Journal of Pancreatology1997，，2： | 1 |
| 19 | Treatment of age-related macular de- generation : focus on ranibizumab 显示文摘 | Martin S Focke Z Karl B | 2008 | Clin Ophthalmol2008，2，1： | 1 |
| 20 | Effect of various fixation parameters on strain development of screw- and cement-retained implant-supported restorations 显示文摘 | Schittenhelm B Karl M Graef F | 2013 | Qui- ntessence Int2013，44，6： | 1 |
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