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317篇 您的检索式:作者名="Lander D"
    题名 作者 年代 出处 被引量
1胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
2A meta- analysis on the anxiety - reducing effects of acute and chronic exercise 显示文摘Petruzzello S J Landers D M Hatfield B D 1991Sports Medicine1991,11,3:1
3Hydrogenation in vitro of α-linoleic acid to stearic acid by mixed cuhures of pure strains of rumen bacteria显示文摘KEMP P LANDER D J 1984J Gen Microbiol1984,130,3:1
4Prevalence and causes of visual impairment in rural Myan- mar: the Meiktila Eye Study 显示文摘Gupta A Casson R J Newland HS Muecke J Landers J Selva D 2007Ophthalmology2007,114,12:1
5A real options approach to valuing strategic flexibility in uncertain construction projects 显示文摘Ford D N Lander D M Voyer J J 2002Construction Management and Economics2002,,20:1
6A meta-analysis on the anxiety-reducing effects of acute and chronic exercise显示文摘PETRUZZELLO S J LANDERS D M HATFIELD B D 1991Sports Med1991,11,3:1
7Reactive oxygen species have a causal role in muhiple forms of insulin resistance 显示文摘Houstis N Rosen E D Lander E S 2006Nature2006,440,7086:1
8A m eta-analysis on the anxiety-reducing effects of acuteandchronic exercise 显示文摘Petruzzello S J Landers D H atfield B D 1991Sports M edicine1991,,11:1
9Resolution of quantitative traits into Mendelian factors by using a comp lete linkagemap of restriction fragment length polymorphisms 显示文摘Paterson A H Lander E S Hewitt J D 1988Nature1988,335,:1
10A comparison of modeling and imaginary in the acqui- sition and retention of motor skills 显示文摘Ram N Riggs S M Landers D M McCullagh P 2007Journal of Sports Sciences2007,25,5:1
11Riparian restoration:current status and the reach to the future显示文摘LANDERS D H 0,,4:1
12Mercury concentrations in salmouids from western US national parks and relationships with age and macrophage aggregates 显示文摘Schwindt A R Fournie J W Landers D H 2008Environmental Science and Technology2008,42,4:1
13Resolution of quanti- tative traits into Mendelian factors by using a complete linkage map of restriction fragment length poiyrnorphisms 显示文摘Paterson A H Lander E S Hewitt J D 1988Nature1988,335,:1
14Reactive oxygen species have a causal role in multiple forms of insulin resistance 显示文摘N Houstis E D Rosen E S Lander 2006Nature2006,440,7086:1
15Association of tumour necrosis factor alpha and its receptors with thymidine phospho- rylase expression in invasive breast carcinoma显示文摘Leek R D Landers R Fox S B 1998Br J Cancer1998,77,12:1
16Mapping mendelian factors underlying quantitative traits using RFLP inkage maps显示文摘LANDER E S BOTSTEIN D 1989Genetics1989,12,1:1
17Hydrogenation in vitro of alpha-linoleic acid to stearic acid by mixed cultures of pure strains of rumen bacteria显示文摘Kemp P Lander D J 1984Journal of Genetic Microbiology1984,130,:1
18Enhanced glypican 3 expression differentiates the majority of bepatoeellular carcinomas from benign hepatic disorders显示文摘Zhu Z W Friess H Wang L Abou Shady M Zimmermann A Lander A D 2001Gut2001,48,:1
19Mappingmendelian factors underlying quantitative traits using RFLP inkage maps显示文摘Lander E S Botstein D 1989Genetics1989,12,1:1
20VB of bacteria fungi protozoa and yeast as analytical tools in food analysis显示文摘Landers R E Gierhart D L 1984Food Anal1984,,3:1
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