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| 1 | The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus. | Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang | 2016 | Science China(Life Sciences)2016，59，9： | 5 |
| 2 | Leaf gas exchange and photosynthesis curves of Elymus nutans and Potentilla anserina under fencing and grazing conditions in the Qilian Mountains, Northwest China显示文摘Potentilla anserina L.and Elymus nutans Griseb.are dominant species in the subalpine meadows of China.Grazing is one of the most important factors that influence community structure and productivity of subalpine meadows.Understanding how grazing changes photosynthetic capability is essential for preservation and restoration of grasslands.However,information about the effects of grazing on photosynthetic capability remains inadequate.Experiments were conducted in fencing and grazing areas in the Qilian Mountains,Northwest China.The leaf gas exchange and photosynthetic curves of P.anserina and E.nutans were measured at different growth stages.Results showed that grazing decreased the values of leaf gas exchange parameters,such as net photosynthetic rate,stomatal conductance,transpiration rate,and intercellular CO2 concentration of P.anserina and E.nutans.In addition,grazing decreased the values of net photosynthetic rate-photosynthetically active radiation(PN-PAR)curve parameters,such as light-saturated net photosynthetic rate,apparent quantum efficiency,light compensation point,light saturation point,and dark respiration rate.Our results demonstrated that grazing was the primary limiting factor for photosynthesis of dominant grassland species in the study area. | LIU Junjie WANG Xiaoping GAO Yunfei RONG Zhanlei ZHANG Guangde WANG Wenbin GE Lijuan MAO Yahua GUO Zhaoxia ZHAO Chuanyan | 2019 | Journal of Arid Land2019，11，3： | 3 |
| 3 | Potential recoverable natural gas resources in China显示文摘在中国的天然气资源是丰富的。在中国的未被发现的可重获的天然气资源被估计是 19.27 敳瀠獯瑩吗? | Liu Chenglin Zhu Jie Che Changbo Liu Guangd | 2008 | Petroleum Science2008，5，1： | 3 |
| 4 | Modified non-rectangular hyperbola equation with plant height for photosynthetic light-response curves of Potentilla anserina and Elymus nutans at various growth phases in the Heihe River Basin, Northwest China显示文摘The non-rectangular hyperbola(NRH)equation is the most popular method that plots the photosynthetic light-response(PLR)curve and helps to identify plant photosynthetic capability.However,the PLR curve can't be plotted well by the NRH equation at different plant growth phases due to the variations of plant development.Recently,plant physiological parameters have been considered into the NRH equation to establish the modified NRH equation,but plant height(H),an important parameter in plant growth phases,is not taken into account.In this study,H was incorporated into the NRH equation to establish the modified NRH equation,which could be used to estimate photosynthetic capability of herbage at different growth phases.To explore photosynthetic capability of herbage,we selected the dominant herbage species Potentilla anserina L.and Elymus nutans Griseb.in the Heihe River Basin,Northwest China as the research materials.Totally,twenty-four PLR curves and H at different growth phases were measured during the growing season in 2016.Results showed that the maximum net photosynthetic rate and the initial slope of PLR curve linearly increased with H.The modified NRH equation,which is established by introducing H and an H-based adjustment factor into the NRH equation,described better the PLR curves of P.anserina and E.nutans than the original ones.The results may provide an effective method to estimate the net primary productivity of grasslands in the study area. | LIU Junjie WANG Xiaoping RONG Zhanlei GAO Yunfei ZHANG Guangde WANGWenbin GE Lijuan MAO Yahua GUO Zhaoxia WANG Qingtao ZHAO Chuanyan | 2019 | Journal of Arid Land2019，11，5： | 1 |
| 5 | The geology and hy- drocarbon potential of petroliferous basins in China 显示文摘 | Li Desheng Liu Guangding Fu Jiamo | 1995 | Epi- sodes1995，18，12： | 1 |
| 6 | Geophysical and geological exploration and hydrocarbon prospects of the East China Sea显示文摘 | Liu Guangding | 1989 | China Earth Sciences1989，1，1： | 1 |
| 7 | The geology and hydrocarbon potential of petroliferous basins in China显示文摘 | Li Desheng Liu Guangding Fu Jiamo | 1995 | Episodes1995，18，12： | 1 |
| 8 | Nonlinear inversion of potential-field data using a hybrid-encoding genetic algorithm显示文摘 | Chao Chen Jianghai Xia Jiangping Liu Guangding Feng | | 0，，02： | 1 |
| 9 | Comparison of Acoustic Radiation Force Impulse Imaging and Transient Elastography for Non-invasive Assessment of Liver Fibrosis in Patients with Chronic Hepatitis B显示文摘 | Dakun Zhang Min Chen Ruifang Wang Yang Liu Dedong Zhang Liping Liu Guangde Zhou | 2014 | Ultrasound in Medicine & Biology2014，，： | 1 |
| 10 | Preparation of nano-porous AlN micro-rods显示文摘In this paper,nano-porous AlN micro-rods were prepared and characterized by X-ray diffraction(XRD),scanning electron microscopy(SEM),transmission electron microscopy(TEM),Brunauer-Emett-Teller(BET) method of nitrogen adsorption at low temperature,UV-via absorption spectrometry and Raman spectrometry.The SEM images and TEM images showed that the AlN samples were micro-size rods with pores in their surfaces evenly.The length of the rod was in the range of a few microns to tens of micron,the diameter of the rods was about one micron,the diameter of the pore was about hundreds of nanometer and the wall thickness of the pore about tens of nanometer.The BET surface area of the sample was 41.424 m 2 /g.The optical spectra showed that the optical properties of the AlN samples almost agreed with that of AlN bulk or film. | YAN GuoJun LIU XiaoLi CHEN GuangDe JIANG BaiLing LI Feng LIU HanCh-en | 2012 | Science China(Technological Sciences)2012，55，6： | 0 |
| 11 | Treatment of 86 Cases of Auditory Vertigo with Acupuncture显示文摘Treatmentof86CasesofAuditoryVertigowithAcupuncture￥WangGuangding;WangHen;LiuJia(AttachedHospitalofYunnanTCMCollegeRedCrossofC... | Wang Guangding Wang Hen Liu Jia(Attached Hospital of Yunnan TCM College Red Cross of China,Yunnan Simao) | 1995 | 中国针灸1995，15，S2： | 0 |
| 12 | Features of Geophysical Fields and Geodynamics of the China Sea显示文摘During 1960—1990, an extensive geological-geophysical investigation was carried out in the marine areas of China. According to the materials obtained, the 'Geological—Geophysical Serial Maps of the China Seas and the Adjacent Areas (1:2,000,000)' was compiled. In fact, it is a systematic summary of the geological and geophysical work of the China Seas in the past 30 years.In this paper, the author explains the guiding thought and methodology of the compilation of the serial maps, and then briefly discusses the characteristics of geophysical fields and geodynamics, stratigraphy, tectonics and magmatism. | Liu Guangding Institute of Geophysics, Academia Sinica, Beijing Sun Sheping | 1993 | Acta Geologica Sinica(English Edition)1993，67，2： | 0 |
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