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| 1 | Introgression of qPE9-1 allele,conferring the panicle erectness,leads to the decrease of grain yield per plant in japonica rice(Oryza sativa L.)显示文摘圆锥花序建筑学是仔细与产量有关形成。qPE9-1 基因被证明了广泛地在产量很高的米饭栽培变种开发被过去常,授与在装饰用的梨树米饭的直立的圆锥花序特性。最近, qPE9-1 成功地被克隆;然而,谷物产量上的基因效果还每直立的圆锥花序等位基因 qPE9-1 的植物是争论的。在现在的学习,低垂的圆锥花序父母 Nongken 57,带 qpe9-1 等位基因,被用作周期性父母到连续地回交到从双 haploid (DH ) 的一根典型直立的圆锥花序线人口(Wuyunjing 8/Nongken 57 ) ,它以前被显示带 qPE9-1 等位基因。因此,一双 near-isogenic 线(无) 被开发。在无之间的农学的特点的比较证明当 qpe9-1 被 qPE9-1 代替时,圆锥花序建筑学从低垂树立被改变;而且,圆锥花序长度,植物高度, 1000 谷物重量和 tillers 显著地被减少,因而在 30% 每植物导致谷物产量的戏剧的减少。因此,我们断定 qPE9-1 是控制圆锥花序建筑学的一个主要因素,并且 qPE9-1 有多种的自然,与每植物的谷物产量上的否定效果。这结果强烈建议直立的圆锥花序等位基因 qPE9-1 应该在产量很高的繁殖实践和另外的有利基因被使用。另外,吃并且煮质量上的 qPE9-1 的效果也在现在的学习被讨论。 | Xiuhua Yi Zujian Zhang Shengyuan Zeng Chunyan Tian Juncheng Peng Min Li Yue Lu Qingcai Meng Minghong Gu Changjie Yan | 2011 | Journal of Genetics and Genomics2011，38，5： | 20 |
| 2 | New microbiota found in sputum from patients with community-acquired pneumonia显示文摘获得社区的肺病(帽子) 是医院和哪个还全身地没被讨论的细菌的社区里的一颗主要担心。从在尖锐阶段的病人的唾沫是反映它的特征的一种可存取的样品。在我们的学习,我们与帽子从 45 个病人分析了 45 件唾沫样品。从健康的人的十八件唾沫样品被选择为控制。在唾沫包含的所有细菌的 16 年代 rDNA V3 hypervariable 区域的 Pyrosequencing 被用作一个文化无关的方法揭示社区体质。另外,我们为在唾沫的获得医院的肺病(幸运) 的出版数据被用于比较。由 pyrosequencing, > 90,000 DNA 读被检测。在被工具在 Ribosomal 数据库工程分析以后, reads 被分类进五个主要的数并且 > 100 个类。在数水平,读的帽子的分发类似于健康的人并且在类水平的,每个类的出现在三个范畴拥有他们的特征。象链球菌和 Neisseria 那样的类在他们的百分比显示出稳定性,显示如此的类被外长的细菌或抗菌素很少影响。象在帽子的 Moraxella 和 Rothia 那样的另外的类的角色应该被强调。根据我们的分析,当时,帽子的细菌的社区与细微变化与那些相比健康的人,但是有在幸运之间的大差距。同时, Rothia 可能是一个重要内长的引起肺病的因素。 | Chunyan Chen Tian Shen Fei Tian Ping Lin Qingtian Li Zelin Cui Yajuan Zhang Min Xue Jing Ye Xiaokui Guo YuhuaZhou | 2013 | Acta Biochimica et Biophysica Sinica2013，45，12： | 3 |
| 3 | Serum uric acid and risk of incident diabetes in middle-aged and elderly Chinese adults: prospective cohort study显示文摘The association between serum uric acid and the risk of incident diabetes in Chinese adults remains unknown.This study aimed to investigate this association in a community-dwelling population aged≥40 years in Shanghai,China.Oral glucose tole3rance test was conducted during baseline and follow-up visits.Relative risk regression was utilized to examine the associations between baseline gender-specific serum uric acid levels and incident diabetes risk.A total of 613(10.3%)incident diabetes cases were identified during the follow-up visit after 4.5 years.Fasting plasma glucose,postload glucose,and glycated hemoglobin A1c during the follow-up visit progressively increased across the sex-specific quartiles of serum uric acid(all Ps<0.05).The incidence rate of diabetes increased across the quartiles of serum uric acid(7.43%,8.77%,11.47%,and 13.43%).Multivariate adjusted regression analysis revealed that individuals in the highest quartile had 1.36-fold increased risk of diabetes compared with those in the lowest quartile of serum uric acid(odds ratio(95%confidence interval)=1.36(1.06−1.73)).Stratified analysis indicated that the association was only observed in women.Accordingly,serum uric acid was associated with the increased risk of incident diabetes among middle-aged and elderly Chinese women. | Di Cheng Chunyan Hu Rui Du Hongyan Qi Lin Lin Xueyan Wu Lina Ma Kui Peng Mian Li Min Xu Yu Xu Yufang Bi Weiqing Wang Yuhong Chen Jieli Lu | 2020 | Frontiers of Medicine2020，14，6： | 3 |
| 4 | Baicalin attenuates global cerebral ischemia/reperfusion injury in gerbils via anti-oxidative and anti-apoptotic pathways显示文摘 | Yonggang Cao Xiaoyuan Mao Chunyan Sun Ping Zheng Jingquan Gao Xiaorui Wang Dongyu Min Hongli Sun Ni Xie Jiqun Cai | 2011 | Brain Research Bulletin2011，，6： | 2 |
| 5 | Influence of Chromatogram Baseline Shifts and Exogenous Metabolite Signals on Metabolic Profiles of Traditional Chinese Medicine Chaihu and Its Liver Toxicity Metabonomics显示文摘 | ZENG Qi FENG Jiangjiang LU Tian XU Liangyu MIN Chunyan XIE Hongping | 2017 | Chemical Research in Chinese Universities2017，33，1： | 2 |
| 6 | Synthesis of 1,2 - aceanthrylenedione catalyzed by anhydrous AlCl3 显示文摘 | Zhang Chunyan Chen Min Yuan Xinhua | 2007 | Materials Science Forum2007，561，： | 1 |
| 7 | Effects of mineral salts on the growth, sporulation and virulence of Esteya vermico- salts eodoparasitic fungus of the pinewood nematode ,Bursaphe- lenchus xylophilus显示文摘 | Wang Zhen Wang Chunyan Liu Min | 2011 | BioContro12011，21，12： | 1 |
| 8 | microRNA - 124 negatively regulates TLR signaling in alveolar macrophages in response to mycobacterial infection显示文摘 | Chunyan Ma Yong L Min Li | 2014 | Molecular immunology2014，62，： | 1 |
| 9 | Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis显示文摘 | Tatiana Kisseleva Min Cong YongHan Paik David Scholten Chunyan Jiang Chris Benner Keiko Iwaisako Thomas Moore-Morris Brian Scott Hidekazu Tsukamoto Sylvia M. Evans Wolfgang Dillmann Christopher K. Glass David A. Brenner | 2012 | Proceedings of the National Academy of Sciences2012，，24： | 1 |
| 10 | NAT10 promotes cell proliferation by acetylating CEP170 mRNA to enhance translation efficiency in multiple myeloma显示文摘Multiple myeloma(MM) is still an incurable hematologic malignancy, which is eagerly to the discovery of novel therapeutic targets and methods. N-acetyltransferase 10(NAT10) is the first reported regulator of mRNA acetylation that is activated in many cancers. However, the function of NAT10 in MM remains unclear. We found significant upregulation of NAT10 in MM patients compared to normal plasma cells, which was also highly correlated with MM poor outcome. Further enforced NAT10 expression promoted MM growth in vitro and in vivo, while knockdown of NAT10 reversed those effects. The correlation analysis of acetylated RNA immunoprecipitation sequencing(ac RIP-seq) and ribosome profiling sequencing(Ribo-seq) combined with RIP-PCR tests identified centrosomal protein 170(CEP170) as an important downstream target of NAT10. Interfering CEP170 expression in NAT10-OE cells attenuated the acceleration of cellular growth caused by elevated NAT10. Moreover,CEP170 overexpression promoted cellular proliferation and chromosomal instability(CIN) in MM.Intriguingly, remodelin, a selective NAT10 inhibitor, suppressed MM cellular growth, induced cellular apoptosis in vitro and prolonged the survival of 5TMM3VT mice in vivo. Collectively, our data indicate that NAT10 acetylates CEP170 mRNA to enhance CEP170 translation efficiency, which suggests that NAT10 may serve as a promising therapeutic target in MM. | Rongfang Wei Xing Cui Jie Min Zigen Lin Yanyan Zhou Mengjie Guo Xiaojuan An Hao Liu Siegfried Janz Chunyan Gu Hongbo Wang Ye Yang | 2022 | Acta Pharmaceutica Sinica B2022，12，8： | 1 |
| 11 | Baicalin attenuates global cerebral ischemia/reperfusion injury in gerbils via anti-oxidative and anti-apoptotic pathways显示文摘 | Yonggang Cao Xiaoyuan Mao Chunyan Sun Ping Zheng Jingquan Gao Xiaorui Wang Dongyu Min Hongli Sun Ni Xie Jiqun Cai | 2011 | Brain Research Bulletin2011，，6： | 1 |
| 12 | Hypoallergenic formula with Lactobacillus rhamnosus GGfor babies with colic:A pilot study of recruitment,retention,and fecal biomarkers显示文摘AIM To investigate recruitment, retention, and estimatesfor effects of formula supplementation withLactobacillus rhamnosus GG (LGG) on inflammatorybiomarkers and fecal microbial community in infants withcolic.METHODS: A prospective, double-blind, placebocontrolledtrial was conducted in otherwise healthyinfants with colic. We screened 74 infants and randomizedand analyzed results in 20 infants [9 receivingLGG (LGG+) and 11 not receiving LGG (LGG-)]. LGG wasincorporated in the formula (Nutramigen?) (minimum of3 × 10^7 CFU/d) in the LGG+ group. Fecal microbiota andinflammatory biomarkers, including fecal calprotectin(FC), plasma cytokines, circulating regulatory T cells(Tregs), and crying + fussing time were analyzed todetermine optimal time points and effect sizes for alarger trial.RESULTS: Recruitment in this population was slow, withabout 66% of eligible infants willing to enroll; subjectretention was better (75%). These rates were influencedby parents' reluctance to volunteer their infant for aclinical trial and by their tendency to change formulas.The maximal difference of crying + fussing time wasobserved at day 14, comparing the 2 groups, with amean difference of -91 (95%CI: -76, 259) min (P = NS).FC showed no significant difference, but the optimaltime to determine a potential effect was at day 90 [witha mean difference of 121 (95%CI: -48, 291) μg/g stool],observing a lower level of FC in the LGG+ group. Thefecal microbial communities were chaotic, as determinedby Shannon's diversity index and not apparently influencedby the probiotic. No significant change wasobserved in plasma inflammatory cytokines or Tregs,comparing LGG+ to LGG- groups.CONCLUSION: Designing future colic trials involving aprobiotic-supplemented formula for infants in the UnitedStates will require consideration for difficult enrollment.Infants with colic have major variations in feal microbiotaand calprotectin, both of which improve with time, withoptimal time points for measurement at days 14 and 90after treatment. | Nicole Y Fatheree Yuying Liu Michael Ferris Melissa Van Arsdall Valarie McMurtry Marcela Zozaya Chunyan Cai Mohammad H Rahbar Manouchehr Hessabi Ta Vu Christine Wong Juleen Min Dat Q Tran Fernando Navarro Wallace Gleason Sara Gonzalez J Marc Rhoads | 2016 | World Journal of Gastrointestinal Pathophysiology2016，7，1： | 1 |
| 13 | Metabolic features of the tumor microenvironment of gastric cancer and the link to the systemic macroenvironment显示文摘 | Jiye Aa Lianzhen Yu Min Sun Linsheng Liu Mengjie Li Bei Cao Jan Shi Jin Xu Liping Cheng Jun Zhou Tian Zheng Xinwen Wang Chunyan Zhao Rongrong Gu Fengyi Zhang Ruihua Shi Guangji Wang | 2012 | Metabolomics2012，，1： | 1 |
| 14 | SYNTHESIS OF FUNCTIONAL MACROMOLECULE INTERMEDIATE THROUGH ACYLATION CATALYZED BY [Emim]Cl-AlCl_3 IONIC LIQUID显示文摘Acylation reaction of anthracene with oxalyl chloride in the presence of [Emim]C1-A1C13 ionic liquid has been investigated. Pure 1,2-aceanthryenedione, which is used as intermediate of functional aromatic polymer material, was obtained by recrystalling the reaction mixture with aether and was determined by GC/MS, 1HNMR and FTIR analysis. The influences of various parameters, such as the contents of AlCl3 in [Emim]C1-A1C13, the amount of acylation agent, amount of [Emim]C1-A1C13, reaction temperature and reaction time were investigated. The optimum conditions were as follows: the molar fraction of A1C13 in ionic liquid [x(AlCl3)] being 0.67 , molar ratio of ionic liquid to anthracene being 2:1 , molar ratio of oxalyl chloride to anthracene being 2:1, reaction temperature being 40℃ and reaction time being 6h. Under above conditions, the yield and selectivity of 1,2-aceanthrylenedione can reach 91.5% and 98.3% respectively. Further more, [Emim]C1-A1C13 ionic liquid, compared with metal halides such as AlCl3, was found to catalyze the reaction as a novel environmental friendly catalyst and solvent and can be reused. | CHEN Min JIANG Deli ZHANG Chunyan YU Long YAN Yongsheng | 2007 | Chinese Journal of Reactive Polymers2007，16，1： | 1 |
| 15 | Enrichment and antioxidant properties of flavone C -glycosides from trollflowers using macroporous resin显示文摘 | Yan Sun Hongyan Yuan Lili Hao Chunyan Min Jinna Cai Jiangyun Liu Peilie Cai Shilin Yang | 2013 | Food Chemistry2013，，： | 1 |
| 16 | Genome sequence and evolution of Betula platyphylla显示文摘Betula L.(birch)is a pioneer hardwood tree species with ecological,economic,and evolutionary importance in the Northern Hemisphere.We sequenced the Betula platyphylla genome and assembled the sequences into 14 chromosomes.The Betula genome lacks evidence of recent whole-genome duplication and has the same paleoploidy level as Vitis vinifera and Prunus mume.Phylogenetic analysis of lignin pathway genes coupled with tissue-specific expression patterns provided clues for understanding the formation of higher ratios of syringyl to guaiacyl lignin observed in Betula species.Our transcriptome analysis of leaf tissues under a time-series cold stress experiment revealed the presence of the MEKK1–MKK2–MPK4 cascade and six additional mitogen-activated protein kinases that can be linked to a gene regulatory network involving many transcription factors and cold tolerance genes.Our genomic and transcriptome analyses provide insight into the structures,features,and evolution of the B.platyphylla genome.The chromosome-level genome and gene resources of B.platyphylla obtained in this study will facilitate the identification of important and essential genes governing important traits of trees and genetic improvement of B.platyphylla. | Su Chen Yucheng Wang Lili Yu Tao Zheng Sui Wang Zhen Yue Jing Jiang Sapna Kumari Chunfang Zheng Haibao Tang Jun Li Yuqi Li Jiongjiong Chen Wenbo Zhang Hanhui Kuang Jon SRobertson Patrick XZhao Huiyu Li Shengqiang Shu Yordan SYordanov Haijiao Huang David MGoodstein Ying Gai Qi Qi JiuMeng Min ChunYan Xu SongBo Wang Guan-Zheng Qu Andrew HPaterson David Sankoff Hairong Wei Guifeng Liu Chuanping Yang | 2021 | Horticulture Research2021，8，1： | 1 |
| 17 | SYNTHESIS OF FUNCTIONAL MACROMOLECULE INTERMEDIATE THROUGH COUPLING REACTION CATALYZED BY [bmim]Cl/FeCl_3 IONIC LIQUID显示文摘To obtain new functional aromatic polymer material, 3,3’-biacenaphthene, which is used as macromolecule intermediate of function aromatic polymer material, was synthesized through the coupling reaction of acenaphthene catalyzing by ionic liquid ([bmim]Cl/FeCl3) at mild reaction condition. Pure 3,3’-biacenaphthene was obtained by recrystalling and column chromatography from the reaction mixture and was determined by GC/MS, 1HNMR and FTIR analysis. The influence of various reaction conditions on the yield of 3,3’-biacenaphthene were studied by GC analysis. The result shows that the optimum synthesis conditions of the coupling reaction are as following: the molar ratio of FeCl3 to [Bmim]Cl being 3, the mole ratio of FeCl3 in [Bmim]Cl/FeCl3 to acenaphthene being 4, the reaction temperature being 20 ℃, the reaction time being 4h and the solvent of the reaction system being PhNO2. Under those conditions, the yield of the 3,3’-biacenaphthene will be 48.71 % and selectivity of that will be 78.56 %. Further more, [bmim]Cl/FeCl3 has no pollution to environments and can be reused. | CHEN Min CHEN Xiaonong YUAN Xinhua ZHANG Yan ZHANG Chunyan LIU Hua DAI Qixun | 2006 | Chinese Journal of Reactive Polymers2006，15，2： | 0 |
| 18 | SYNTHESIS OF 1,2-ACEANTHRYLENEDIONE THROUGH ACYLATION OF ANTHRACENE WITH OXALYL CHLORIDE显示文摘Acylation of anthracene and oxalyl chloride in the presence of anhydrous AlCl3 was investigated. Pure 1,2-aceanthrylenedione, which is used as new functional macromolecule, was prepared by extraction and recrystallation. The structure of 1,2-aceanthrylenedione was identified by measure of melting point, GC/MS, FTIR and 1HNMR analyses. The influences of various parameters, such as solvent, dosage of catalyst, molar ratio of anthracene to oxalyl chloride, reaction temperature, and reaction time were studied. The anhydrous AlCl3 was found to catalyze the reaction with high yeild and good selectivity. When the reaction temperature is 303K, reaction time is 5h and molar ratio of anthracene to oxalyl chloride is 1:2, the yield and selectivity of 1,2-aceanthrylenedione is 83.8 % and 92.3% respectively. | ZHANG Chunyan CHEN Min YU Long JIANG Deli YAN Yongsheng | 2007 | Chinese Journal of Reactive Polymers2007，16，1： | 0 |
| 19 | Formaldehyde accelerates cellular senescence in HT22 cells: possible involvement of the leptin pathway显示文摘甲醛(FA ) ,一种著名环境污染物质,是在民族生活的广泛地使用的化学混合物。深刻研究证明了 FA 在中央神经系统上有有毒的效果[1 ] 。然而,位于导致 FA 的 neurotoxicity 下面的机制充分没被调查。发现一个方法阻止并且慢下来引起 FA 的 neurotoxicity 的前进也是必要的。细胞的老朽,导致永久房间周期拘捕的规划房间回答,能被象 oncogene 激活,照耀, DNA 损坏和氧化应力那样的各种各样的细胞的压力导致[2 ] 。最近的研究建议了在大脑的衰老的房间可以贡献 neurodegenerative 变化[3 ] 。有趣地,积累了 FA 在使个人变老的大脑被报导了并且贡献年龄相关的 neurodegenerative 症状[4 ] 。因此, FA 能加速细胞的老朽,这被假设并且它可以接着贡献得到 FA 的 neurotoxicity。 | Kebin Zhan Min Ning Chunyan Wang Yonghong Tang Hongfeng Gu Canqun Yan Xiaoqing Tang | 2016 | Acta Biochimica et Biophysica Sinica2016，48，8： | 0 |
| 20 | Review on herbal tea as a functional food:classification,active compounds,biological activity,and industrial status显示文摘Most herbal tea infusions use edible medicinal plants as raw material and are consumed daily.Although herbal tea has a long history of health care applications worldwide,there is a lack of systematic research on the classification and functional nutritional value of various herbal teas.In recent years,the discovery of the rich biological activities and health benefits of herbal tea has become a driving force for researchers interested in its development as a functional food.However,the shortcomings of herbal tea products are not fully known.In particular,the quality evaluation system is not perfect,and there is insufficient data on the mechanism of action of herbal teas in their traditional uses.To better understand the functions and mechanisms of various herbal teas,this article reviews the classification,effective chemical composition,main biological activities,and mechanism of action of herbal teas.Finally,the current advantages,limitations,and direction of future development of herbal tea are determined and discussed. | Yuchao Liu Chunyan Guo Erhuan Zang Ruyu Shi Qian Liu Min Zhang Keyong Zhang Minhui Li | 2023 | Journal of Future Foods2023，3，3： | 0 |
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