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| 1 | Transcranial direct current stimulation in psychiatric disorders显示文摘The interest in non-invasive brain stimulation techniques is increasing in recent years. Among these techniques, transcranial direct current stimulation(t DCS) has been the subject of great interest among researchers because of its easiness to use, low cost, benign profile of side effects and encouraging results of research in the field. This interest has generated several studies and randomized clinical trials, particularly in psychiatry. In this review, we provide a summary of the development of the technique and its mechanism of action as well as a review of the methodological aspects of randomized clinical trials in psychiatry, including studies in affective disorders, schizophrenia, obsessive compulsive disorder, child psychiatry and substance use disorder. Finally,we provide an overview of t DCS use in cognitive enhancement as well as a discussion regarding its clinical use and regulatory and ethical issues. Although many promising results regarding t DCS efficacy were described, the total number of studies is still low, highlighting the need of further studies aiming to replicate these findings in larger samples as to provide a definite picture regarding t DCS efficacy in psychiatry. | Gabriel Tortella Roberta Casati Luana V M Aparicio Antonio Mantovani Natasha Senco Giordano D’Urso Jerome Brunelin Fabiana Guarienti Priscila Mara Lorencini Selingardi Débora Muszkat Bernardo de Sampaio Pereira Junior Leandro Valiengo Adriano H Moffa Marcel Simis Lucas Borrione André R Brunoni | 2015 | World Journal of Psychiatry2015，5，1： | 6 |
| 2 | Model combining pre-transplant tumor biomarkers and tumor size shows more utility in predicting hepatocellular carcinoma recurrence and survival than the BALAD models显示文摘AIM To assess the performance of BALAD, BALAD-2 and their component biomarkers in predicting outcome of hepatocellular carcinoma(HCC) patients after liver transplant.METHODS BALAD score and BALAD-2 class are derived from bilirubin, albumin, alpha-fetoprotein(AFP), Lens culinaris agglutinin-reactive AFP(AFP-L3), and des-gammacarboxyprothrombin(DCP). Pre-transplant AFP, AFP-L3 and DCP were measured in 113 patients transplanted for HCC from 2000 to 2008. Hazard ratios(HR) for recurrence and death were calculated. Univariate and multivariate regression analyses were conducted. C-statistics were used to compare biomarker-based to predictive models. RESULTS During a median follow-up of 12.2 years, 38 patients recurred and 87 died. The HRs for recurrence in patients with elevated AFP, AFP-L3, and DCP defined by BALAD cut-off values were 2.42(1.18-5.00), 1.86(0.98-3.52), and 2.83(1.42-5.61), respectively. For BALAD, the HRs for recurrence and death per unit increased score were 1.48(1.15-1.91) and 1.59(1.28-1.97). For BALAD-2, the HRs for recurrence and death per unit increased class were 1.45(1.06-1.98) and 1.38(1.09-1.76). For recurrence prediction, the combination of three biomarkers had the highest c-statistic of 0.66 vs. 0.64, 0.61, 0.53, and 0.53 for BALAD, BALAD-2, Milan, and UCSF, respectively. Similarly, for death prediction, the combination of three biomarkers had the highest c-statistic of 0.66 vs 0.65,0.61, 0.52, and 0.50 for BALAD, BALAD-2, Milan, and UCSF. A new model combining biomarkers with tumor size at the time of transplant(S-LAD) demonstrated the highest predictive capability with c-statistics of 0.71 and 0.69 for recurrence and death. CONCLUSION BALAD and BALAD-2 are valid in transplant HCC patients, but less predictive than the three biomarkers in combination or the three biomarkers in combination with maximal tumor diameter(S-LAD). | Nicha Wongjarupong Gabriela M Negron-Ocasio Roongruedee Chaiteerakij Benyam D Addissie Essa A Mohamed Kristin C Mara William S Harmsen J Paul Theobald Brian E Peters Joseph G Balsanek Melissa M Ward Nasra H Giama Sudhakar K Venkatesh Denise M Harnois Michael R Charlton Hiroyuki Yamada Alicia Algeciras-Schimnich Melissa R Snyder Terry M Therneau Lewis R Roberts | 2018 | World Journal of Gastroenterology2018，24，12： | 5 |
| 3 | Laparoscopy in chronic Pelvicpain-a retrospective cllnical study显示文摘 | Mara M Fucikova Z kuzel D | | Ceska Gynekol0，67，1： | 1 |
| 4 | Validating the Migraine-Specific Quality of Life Questionnaire v2.1 (MSQ) in Italian inpatients with chronic migraine with a history of medication overuse显示文摘 | Alberto Raggi Ambra Mara Giovannetti Silvia Schiavolin Matilde Leonardi Gennaro Bussone Licia Grazzi Susanna Usai Marcella Curone Paola Fiore Domenico D’Amico | 2014 | Quality of Life Research2014，，4： | 1 |
| 5 | Water stabilization ponds past present and fu- ture显示文摘 | Mara D | 2009 | Desalination and Water Treatment2009，，4： | 1 |
| 6 | Extending shelf-life and nutritive value of green beans(Phaseolus Vulgaris L ),by controlled atmosphere storage:macronutrients显示文摘 | Sánchez-Mata MC Cámara M D | | 0，，03： | 1 |
| 7 | Application of athree-dimensional network model to the coke formation in FAU,MFI and BEA zeolites 显示文摘 | Ca^mara L D T Cerqueira H S Aranda DAG | 2004 | Catalysis Today2004，，98： | 1 |
| 8 | Frequency and fracture morphology of the posteromedial fragment in bicondylar tibial plateau fracture patterns显示文摘 | Barei D P O’Mara T J Taitsman L A | 2008 | Jrthop Trauma2008，22，3： | 1 |
| 9 | Sorbitol-fermenting bifidobacteria as specific in- dicators of human faecal pollution显示文摘 | Mara D D Oragui J I | 1983 | Journal of Applied Bacteriology1983，55，2： | 1 |
| 10 | Good quality sheep embryos produced by superovulation treatment without the use of progesterone devices显示文摘 | MAYORGA I MARA L SANNA D | 2011 | Theri-ogenology2011，75，9： | 1 |
| 11 | Occurrence of Rhodococcus coprophilus and as- sociated aetinomycetes in feces, sewage, and freshwater显示文摘 | Mara D D Oragui J I | 1981 | Applied & Envirouraental Microbiology1981，42，6： | 1 |
| 12 | Covered stent-graft treatment of traumatic internal carotid artery pseudoaneurysms:a review显示文摘 | Maras D Lioupis C Magoufis G | 2006 | Cardiovasc Intervent Radiol2006，29，： | 1 |
| 13 | Laparoscopyinchronic-pelVic pain-aretrospeclinicalstudy显示文摘 | Mara M Fucikova Z Kuzel D | 2002 | Ceska Gynekol2002，67，1： | 1 |
| 14 | In vivo synthesis of complex N-glycans by expression of human N-acetylglu-cosaminyltransferaseⅠin the filamentous fungus Trichoderma reesei显示文摘 | Maras M Bruyn A D Vervecken W | 1999 | FEBS Letters1999，452，： | 1 |
| 15 | Low cost controlled comp- osting of refuse and sewage sludge显示文摘 | PEREIA J T STENTIFORD E I MARA D D | 1987 | Water Science and Technology1987，，19： | 1 |
| 16 | Management of domestic wastewater for reuse in irrigation显示文摘 | Vazquezmontiel O Horan N J Mara D D | 1996 | Water Sci Technol1996，33，1011： | 1 |
| 17 | Thyroid hormones and methylmercury toxicity显示文摘 | SOLDIN O P O'MARA D M ASCHNER M | 2008 | Biol Trace Elem Res2008，126，13： | 1 |
| 18 | Comparative outcomes of hystero- scopic examinations performed after uterine artery embolization or laparoscopic uterine artery occlusion to treat leiomyomas显示文摘 | Kuzel D Mara M Horak P | 2011 | Fertil Steri12011，95，6： | 1 |
| 19 | Frequency and fracture morphology of lh posleromedial fi'agment in bicondylar tibial plateau fracture pallerns显示文摘 | Barei D P 0' Mara T J Taitsman L A at al | 2008 | J Orlhop Trauma2008，22，2： | 1 |
| 20 | Postprandial hypotension显示文摘 | Lyons D | 2002 | Clin Geriatr Med2002，18，2： | 1 |
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