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7篇 您的检索式:作者名="Maria Piques"
    题名 作者 年代 出处 被引量
1New genes emerging for colorectal cancer predisposition显示文摘Colorectal cancer(CRC)is one of the most frequent neoplasms and an important cause of mortality in the developed world.This cancer is caused by both genetic and environmental factors although 35%of the variation in CRC susceptibility involves inherited genetic differences.Mendelian syndromes account for about5%of the total burden of CRC,with Lynch syndrome and familial adenomatous polyposis the most common forms.Excluding hereditary forms,there is an important fraction of CRC cases that present familial aggregation for the disease with an unknown germline genetic cause.CRC can be also considered as a complex disease taking into account the common diseasecommom variant hypothesis with a polygenic model of inheritance where the genetic components of common complex diseases correspond mostly to variants of low/moderate effect.So far,30 common,low-penetrance susceptibility variants have been identified for CRC.Recently,new sequencing technologies including exomeand whole-genome sequencing have permitted to add a new approach to facilitate the identification of new genes responsible for human disease predisposition.By using whole-genome sequencing,germline mutations in the POLE and POLD1 genes have been found to be responsible for a new form of CRC genetic predisposition called polymerase proofreading-associated polyposis.Clara Esteban-Jurado Pilar Garre Maria Vila Juan José Lozano Anna Pristoupilova Sergi Beltrán Anna Abulí Jenifer Muoz Francesc Balaguer Teresa Ocaa Antoni Castells Josep M Piqué Angel Carracedo Clara Ruiz-Ponte Xavier Bessa Montserrat Andreu Luis Bujanda Trinidad Caldés Sergi Castellví-Bel 2014World Journal of Gastroenterology2014,20,8:3
2Anemia Worsens Hyperdynamic Circulation of Patients with Cirrhosis and Portal Hypertension显示文摘Isabel Cirera Josep I. Elizalde Josep M. Pique Faust Feu Maria Casadevall Eran Goldin Josep Teres Jaume Bosch Juan Rodes 1997Digestive Diseases and Sciences1997,,8:1
3Endoscopic ultrasound-guided fine needle aspiration: predictive factors of accurate diagnosis and cost-minimization analysis of on-site pathologist显示文摘Maria Pellisé Urquiza Glòria Fernández-Esparrach Manel Solé Lluís Colomo Antoni Castells Josep Llach Alfredo Mata Josep M. Bordas Josep M. Piqué àngels Ginès 2007Gastroenterologia y Hepatologia2007,,6:1
4Laparoscopic-assisted vs. open colectomy for colorectal cancer: Influence on neoplastic cell mobilization显示文摘Xavier Bessa M.D. Dr. Antoni Castells M.D. Antonio M. Lacy M.D. J. Ignasi Elizalde M.D. Salvadora Delgado M.D. Loreto Boix Ph.D. Virginia Pi?ol M.D. Maria Pellisé M.D. Juan C. García-Valdecasas M.D. Josep M. Piqué M.D 2001Journal of Gastrointestinal Surgery2001,,1:1
5Aspirin induces apoptosis in human leukemia cells independently of NF-κB and MAPKs through alteration of the Mcl-1/Noxa balance显示文摘Daniel Iglesias-Serret Maria Piqué Montserrat Barragán Ana M. Cosialls Antonio F. Santidrián Diana M. González-Gironès Lloren? Coll-Mulet Mercè Frias Gabriel Pons Joan Gil 2010Apoptosis2010,,2:1
6Impact of Wide-Angle, High-Definition Endoscopy in the Diagnosis of Colorectal Neoplasia: A Randomized Controlled Trial显示文摘Maria Pellisé Glòria Fernández–Esparrach Andrés Cárdenas Oriol Sendino Elena Ricart Eva Vaquero Antonio Z. Gimeno–García Cristina Rodríguez de Miguel Michel Zabalza Angels Ginès Josep M. Piqué Josep Llach Antoni Castells 2008Gastroenterology2008,,4:1
7Arabidopsis thaliana plants acclimate to water deficit at low cost through changes of C usage; an integrated perspective using growth, metabolite, enzyme and gene expression analysis显示文摘Irene Hummel Florent Pantin Ronan Sulpice Maria Piques Ga? lie Rolland Myriam Dauzat Ang61ique Christophe Marjorie Per- vent Marie Bouteill6 Mark Stitt Yves Gibon Bertrand Muller 2010Plant Physiolo- gy2010,154,:1
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