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6篇 您的检索式：作者名="Marschall S Runge"

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		题名	作者	年代	出处	被引量
	1	Genetics of coronary artery disease and myocardial infarction显示文摘Atherosclerotic coronary artery disease(CAD) comprises a broad spectrum of clinical entities that include asymptomatic subclinical atherosclerosis and its clinical complications, such as angina pectoris, myocardial infarction(MI) and sudden cardiac death. CAD continues to be the leading cause of death in industrialized society. The long-recognized familial clustering of CAD suggests that genetics plays a central role in its development, with the heritability of CAD and MI estimated at approximately 50% to 60%. Understanding the genetic architecture of CAD and MI has proven to be difficult and costly due to the heterogeneity of clinical CAD and the underlying multi-decade complex pathophysiological processes that involve both genetic and environmental interactions. This review describes the clinical heterogeneity of CAD and MI to clarify the disease spectrum in genetic studies, provides a brief overview of the historical understanding and estimation of the heritability of CAD and MI, recounts major gene discoveries of potential causal mutations in familial CAD and MI, summarizes CAD and MIassociated genetic variants identified using candidate gene approaches and genome-wide association studies(GWAS), and summarizes the current status of the construction and validations of genetic risk scores for lifetime risk prediction and guidance for preventive strategies. Potential protective genetic factors against the development of CAD and MI are also discussed. Finally, GWAS have identified multiple genetic factors associated with an increased risk of in-stent restenosis following stent placement for obstructive CAD. This review will also address genetic factors associated with in-stent restenosis, which may ultimately guide clinical decision-making regarding revascularization strategies for patients with CAD and MI.	Xuming Dai Szymon Wiernek James P Evans Marschall S Runge	2016	World Journal of Cardiology2016，8，1：	15
	2	Cardiac troponin T in chest pain unit patients without ischemic electrocardiographic changes: angiographic correlates and long-term clinical outcomes显示文摘	Christopher R deFilippi Monica Tocchi Rohit J Parmar Salvatore Rosanio Gerard Abreo Marjorie A Potter Marschall S Runge Barry F Uretsky	2000	Journal of the American College of Cardiology2000，，7：	1
	3	Angiotensin induces interleukin-6 transcription in vascular smooth muscle cells through pleiotropic activation of nuclear factor-κB transcription factors显示文摘	Youqi Han Marschall S Runge	1999	Circulation1999，84，：	1
	4	Randomized comparison of a strategy of predischarge coronary angiography versus exercise testing in low-risk patients in a chest pain unit: in-hospital and long-term outcomes显示文摘	Christopher R deFilippi Salvatore Rosanio Monica Tocchi Rohit J Parmar Marjorie A Potter Barry F Uretsky Marschall S Runge	2001	Journal of the American College of Cardiology2001，，8：	1
	5	Sudden cardiac death in a teenager:a review of Kawasaki Disease显示文摘	Rung E Marschall S	1998	Am J Med Sci1998，315，：	1
	6	Role of monocyte chemoattractant protein-1 (MCP-1) as an immune-diagnostic biomarker in the pathogenesis of chronic periodontal disease显示文摘	Youqi H an Marschall S Runge		0，，：	1

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