|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Type 2 diabetes mellitus:From a metabolic disorder to an inflammatory condition显示文摘Diabetes mellitus is increasing at an alarming rate and has become a global challenge.Insulin resistance intarget tissues and a relative deficiency of insulin secretion from pancreatic β-cells are the major features of type 2 diabetes(T2D).Chronic low-grade inflammation in T2 D has given an impetus to the field of immuno-metabolism linking inflammation to insulin resistance and β-cell dysfunction.Many factors advocate a causal link between metabolic stress and inflammation.Numerous cellular factors trigger inflammatory signalling cascades,and as a result T2 D is at the moment considered an inflammatory disorder triggered by disordered metabolism.Cellular mechanisms like activation of Tolllike receptors,Endoplasmic Reticulum stress,and inflammasome activation are related to the nutrient excess linking pathogenesis and progression of T2 D with inflammation.This paper aims to systematically review the metabolic profile and role of various inflammatory pathways in T2 D by capturing relevant evidence from various sources.The perspectives include suggestions for the development of therapies involving the shift from metabolic stress to homeostasis that would favour insulin sensitivity and survival of pancreatic β-cells in T2 D. | Iqra Hameed Shariq R Masoodi Shahnaz A Mir Mudasar Nabi Khalid Ghazanfar Bashir A Ganai | 2015 | World Journal of Diabetes2015，6，4： | 36 |
| 2 | Cytokine- and chemokine-induced inflammatory colorectal tumor microenvironment: Emerging avenue for targeted therapy显示文摘Colorectal cancer(CRC)is a predominant life-threatening cancer,with liver and peritoneal metastases as the primary causes of death.Intestinal inflammation,a known CRC risk factor,nurtures a local inflammatory environment enriched with tumor cells,endothelial cells,immune cells,cancer-associated fibroblasts,immunosuppressive cells,and secretory growth factors.The complex interactions of aberrantly expressed cytokines,chemokines,growth factors,and matrix-remodeling enzymes promote CRC pathogenesis and evoke systemic responses that affect disease outcomes.Mounting evidence suggests that these cytokines and chemokines play a role in the progression of CRC through immunosuppression and modulation of the tumor microenvironment,which is partly achieved by the recruitment of immunosuppressive cells.These cells impart features such as cancer stem cell-like properties,drug resistance,invasion,and formation of the premetastatic niche in distant organs,promoting metastasis and aggressive CRC growth.A deeper understanding of the cytokineand chemokine-mediated signaling networks that link tumor progression and metastasis will provide insights into the mechanistic details of disease aggressiveness and facilitate the development of novel therapeutics for CRC.Here,we summarized the current knowledge of cytokine-and chemokine-mediated crosstalk in the inflammatory tumor microenvironment,which drives immunosuppression,resistance to therapeutics,and metastasis during CRC progression.We also outlined the potential of this crosstalk as a novel therapeutic target for CRC.The major cytokine/chemokine pathways involved in cancer immunotherapy are also discussed in this review. | Ajaz A.Bhat Sabah Nisar Mayank Singh Bazella Ashraf Tariq Masoodi Chandra P.Prasad Atul Sharma Selma Maacha Thasni Karedath Sheema Hashem Syed Besina Yasin Puneet Bagga Ravinder Reddy Michael P.Frennaux Shahab Uddin Punita Dhawan Mohammad Haris Muzafar A.Macha | 2022 | Cancer Communications2022，42，8： | 8 |
| 3 | Esophagitis dissecans superficialis presenting with massive haematemesis in a patient with bullous pemphig- oid显示文摘 | Tijjani BM Masoodi 1 Hassan SN | 2013 | Niger J Med2013，22，4： | 1 |
| 4 | Epidemiologic aspects of postpartum pituitary hypofunction (Sheehan’s syndrome)显示文摘 | Abdul Hamid Zargar Bikram Singh Bashir Ahmad Laway Shariq Rashid Masoodi Arshad Iqbal Wani Mir Iftikhar Bashir | 2005 | Fertility and Sterility2005，，2： | 1 |
| 5 | Applications of metabolomics for understanding the action of peroxisome proliferator-activated receptors (PPARs) in diabetes,obesity and cancer显示文摘 | Ament Z Masoodi M Griffin JL | | 0，，： | 1 |
| 6 | Quality of care of vascular access in hemodialysis patients in a hemodialysis center in Iran显示文摘 | Mohsen Adib-Hajbaghery Narjes Molavizadeh Negin Masoodi Alavi | 2012 | Journal of Vascular Nursing2012，，： | 1 |
| 7 | Exploration of deleterious single nucleotide polymorphisms in late-onset Alzheimer disease susceptibility genes显示文摘 | Masoodi TA Al Shammari SA Al-Muammar MN | | 0，，02： | 1 |
| 8 | Omeprazole as adjuvant therapy to endoscopic combination injection sclerotherapy for treating bleeding peptic ulcer显示文摘 | Javid G Masoodi I Zargar SA | 2001 | Am J Med2001，111，4： | 1 |
| 9 | Clinical factors associated with hyperkalemia in patients with congestive heart failure显示文摘 | RAMADAN FH MASOODI N EL-SOLH AA | 2005 | J Clin Pharm Ther2005，30，3： | 1 |
| 10 | Physico-chemical, morphological and pasting properties of starches extracted from water chestnuts (Trapa natans) from three lakes of Kashmir, India显示文摘 | GANI A HAQ S S MASOODI F A | 2010 | Brazilian Archives of Biology and Technology2010，53，3： | 1 |
| 11 | Use of apple pomace as a source o{ dietary fiber cakes显示文摘 | Masoodi F A Sharma B Chauhan G S | 2002 | Plant Foods {or Human Nutrition2002，57，2： | 1 |
| 12 | Comparative study of the physico-chemical properties of rice and corn starches grown in Indian temperate climate显示文摘 | Abida Ali Touseef Ahmed Wani Idrees Ahmed Wani Farooq Ahmad Masoodi | 2014 | Journal of the Saudi Society of Agricultural Sciences2014，，： | 1 |
| 13 | Functional genomics based prioritization of potential nsSNPs in EPHX1, GSTT1, GSTM1 and GSTP1 genes for breast cancer susceptibility studies 显示文摘 | Masoodi TA Rao Talluri V Shaik NA | 2012 | Genom- ics2012，99，6： | 1 |
| 14 | Copper,Zinc and magnesium levels in type Ⅰ diabetesmellitus显示文摘 | Zaryar AH Bashiu MI Masoodi SR | 2002 | SaudiMed2002，23，： | 1 |
| 15 | Effect of particle size on surface properties of apple pomace显示文摘 | Ss Grover Gs Chauhan Fa Masoodi | | 0，，1： | 1 |
| 16 | Use of apple pomace sa a source of dietary fiber in cakes 显示文摘 | Masoodi F A Bhawana Sharma Chauhan G S | 2002 | Plant Foods for Human Nutrition2002，57，2： | 1 |
| 17 | Prevalence and pattern of sick euthyroid syndrome in acute and chronic non-thyroidal illness-its relationship with severity and outcome of the disorder 显示文摘 | Zargar AH Ganie MA Masoodi SR | 2004 | J Assoc Physicians India2004，52，： | 1 |
| 18 | Infusing teaching thinking skills into subject-area instruction显示文摘 | Su W M Masoodi J Kopp M | 1998 | Nurse Educator1998，23，4： | 1 |
| 19 | Use of apple pom-ace as a source of dietary fiber cakes 显示文摘 | Masoodi F A Sharma B Chauhan G S | 2002 | Plant Foods forHuman Nutrition2002，57，2： | 1 |
| 20 | Lipid signaling in adipose tissue: Connecting inflammation & metabolism显示文摘 | Masoodi M Kuda O Rossmeisl M | 2015 | Biochim Biophys Acta2015，1851，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员